Experiment set1IT010 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Sodium L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4596 -6.6 -11.1 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3783 -6.5 -6.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3630 -6.4 -7.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4826 -6.4 -7.6 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3842 -6.3 -6.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4597 -6.0 -12.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_77 -6.0 -7.1 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3839 -5.9 -5.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_71 -5.8 -8.0 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4825 -5.7 -10.9 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3782 -5.7 -6.7 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4762 -5.6 -5.1 Biotin synthesis protein BioH compare
Pf6N2E2_3248 -5.4 -6.3 Probable transmembrane protein compare
Pf6N2E2_5175 -5.4 -18.4 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4047 -5.3 -7.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3384 -5.2 -7.4 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_3751 -5.2 -16.1 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_5176 -5.1 -13.7 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3382 -5.1 -10.4 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3752 -4.7 -24.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3253 -4.7 -9.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3610 -4.6 -5.3 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4279 -4.6 -15.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3383 -4.6 -7.0 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_2074 -4.6 -2.9 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4278 -4.6 -13.4 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_2277 -4.5 -4.4 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_64 -4.5 -6.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4564 -4.5 -9.5 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3932 -4.4 -5.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4759 -4.4 -18.2 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_2073 -4.4 -10.5 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4277 -4.3 -11.2 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_3940 -4.2 -12.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3841 -4.2 -6.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_5666 -4.0 -13.0 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_5177 -4.0 -10.7 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4638 -4.0 -5.4 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3381 -4.0 -9.1 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_4764 -3.8 -7.7 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_3252 -3.7 -7.2 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_4763 -3.6 -10.8 Biotin synthesis protein BioC compare
Pf6N2E2_5014 -3.6 -2.3 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3251 -3.6 -14.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_66 -3.6 -7.5 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4761 -3.6 -12.1 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_4048 -3.6 -6.7 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3380 -3.4 -9.4 L-lactate permease compare
Pf6N2E2_5527 -3.4 -4.5 Cold shock protein CspC compare
Pf6N2E2_4797 -3.2 -2.6 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_302 -3.1 -7.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5006 -3.1 -10.6 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_5728 -3.1 -5.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_63 -3.1 -6.9 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_5579 -3.0 -7.0 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4631 -3.0 -8.8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_5156 -2.9 -4.8 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4987 -2.7 -2.1 MaoC-like domain protein compare
Pf6N2E2_50 -2.7 -10.4 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_2465 -2.7 -6.2 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3170 -2.7 -6.5 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5667 -2.6 -10.5 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_2534 -2.3 -6.9 Cell division protein BolA compare
Pf6N2E2_248 -2.1 -10.2 hypothetical protein compare
Pf6N2E2_3984 -2.0 -10.9 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_6140 -2.0 -1.7 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_5001 -2.0 -3.3 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_2753 -2.0 -3.5 HtrA protease/chaperone protein compare
Pf6N2E2_2586 -2.0 -2.9 Hpt domain protein compare
Pf6N2E2_2473 -1.7 -2.0 Major outer membrane lipoprotein I compare
Pf6N2E2_4009 -1.7 -7.2 GGDEF domain protein compare
Pf6N2E2_3938 -1.7 -11.2 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3533 -1.7 -6.3 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_5950 -1.7 -5.1 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2313 -1.7 -4.6 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_5103 -1.7 -1.5 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_2514 -1.6 -4.1 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_178 -1.6 -1.6 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_3349 -1.6 -3.6 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2549 -1.6 -2.7 hypothetical protein compare
Pf6N2E2_2217 -1.5 -6.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_2286 -1.5 -3.7 FIG00953287: hypothetical protein compare
Pf6N2E2_5190 -1.4 -8.6 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_4206 -1.4 -2.6 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_5258 -1.4 -6.7 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_3095 -1.4 -1.7 hypothetical protein compare
Pf6N2E2_4579 -1.3 -2.4 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_2186 -1.3 -4.1 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_2317 -1.3 -5.0 Putative analog of CcoH, COG3198 compare
Pf6N2E2_3461 -1.3 -1.4 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_2318 -1.3 -7.5 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_5257 -1.3 -7.3 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_5553 -1.2 -6.7 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_4372 -1.2 -3.7 FIG00460773: hypothetical protein compare
Pf6N2E2_5676 -1.2 -4.6 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_3198 -1.2 -2.4 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_4803 -1.2 -1.8 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_3899 -1.2 -6.3 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_5155 -1.2 -2.3 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_2200 -1.2 -2.1 RNA polymerase sigma-54 factor RpoN compare
Pf6N2E2_2693 -1.2 -2.0 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_623 -1.2 -1.6 FIG00954674: hypothetical protein compare
Pf6N2E2_3346 -1.2 -4.7 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_5520 -1.1 -4.5 Sensory box histidine kinase compare
Pf6N2E2_2646 -1.1 -1.4 FIG00953416: hypothetical protein compare
Pf6N2E2_4039 -1.1 -4.1 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf6N2E2_5739 -1.1 -1.3 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_3460 -1.1 -1.8 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2068 -1.1 -6.3 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_3835 -1.1 -4.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5452 -1.1 -2.1 hypothetical protein compare
Pf6N2E2_3534 -1.1 -2.8 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_6085 -1.1 -2.7 Aha1 domain superfamily compare
Pf6N2E2_4040 -1.1 -8.3 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) compare
Pf6N2E2_156 -1.0 -2.7 Carbon storage regulator compare
Pf6N2E2_2447 -1.0 -3.7 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_2065 -1.0 -2.6 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_4928 -1.0 -1.9 Permeases of the major facilitator superfamily compare
Pf6N2E2_3282 -1.0 -2.3 FIG005080: Possible exported protein compare
Pf6N2E2_1718 -1.0 -3.2 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_2218 -1.0 -3.8 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_51 -1.0 -4.9 hypothetical protein compare
Pf6N2E2_4038 -1.0 -6.2 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf6N2E2_5316 -1.0 -1.4 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_5252 -1.0 -1.0 FIG00956396: hypothetical protein compare
Pf6N2E2_2389 -1.0 -6.9 Phosphoenolpyruvate synthase (EC 2.7.9.2) compare
Pf6N2E2_5030 -1.0 -4.4 Transcriptional regulator, AsnC family compare
Pf6N2E2_5669 -1.0 -4.0 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_3770 -0.9 -1.6 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_2420 -0.9 -1.8 hypothetical protein compare
Pf6N2E2_4476 -0.9 -5.1 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_4417 -0.9 -3.8 Protein of unknown function DUF484 compare
Pf6N2E2_5219 -0.9 -5.9 FIG140336: TPR domain protein compare
Pf6N2E2_2310 -0.9 -6.5 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_5714 -0.9 -2.7 Flavoprotein WrbA compare
Pf6N2E2_3901 -0.9 -2.2 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
Pf6N2E2_2496 -0.9 -1.6 FIG00956575: hypothetical protein compare
Pf6N2E2_2756 -0.9 -5.4 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_2640 -0.9 -1.4 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_5665 -0.9 -3.7 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_2320 -0.9 -2.5 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_2080 -0.9 -1.3 hypothetical protein compare
Pf6N2E2_5746 -0.9 -2.7 Cobalamin synthase compare
Pf6N2E2_2258 -0.9 -5.0 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_88 -0.9 -1.4 hypothetical protein compare
Pf6N2E2_3122 -0.8 -1.4 Chemotaxis signal transduction protein compare
Pf6N2E2_3607 -0.8 -4.5 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_1636 -0.8 -5.5 Ferrichrome-iron receptor compare
Pf6N2E2_4205 -0.8 -2.7 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_4454 -0.8 -3.0 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_746 -0.8 -1.5 FIG00958097: hypothetical protein compare
Pf6N2E2_2311 -0.8 -4.4 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_2285 -0.8 -1.5 FIG00954079: hypothetical protein compare
Pf6N2E2_622 -0.8 -3.9 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_2223 -0.8 -1.8 hypothetical protein compare
Pf6N2E2_3027 -0.8 -1.3 Baseplate assembly protein V compare
Pf6N2E2_5111 -0.8 -2.5 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_631 -0.8 -4.0 2-ketogluconate utilization repressor PtxS compare
Pf6N2E2_4418 -0.8 -0.7 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_3840 -0.8 -2.0 FIG00956267: hypothetical protein compare
Pf6N2E2_5425 -0.8 -1.4 hypothetical protein compare
Pf6N2E2_1717 -0.8 -4.8 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_2367 -0.8 -1.7 hypothetical protein compare
Pf6N2E2_3661 -0.8 -2.1 hypothetical protein compare
Pf6N2E2_3535 -0.8 -3.9 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
Pf6N2E2_4307 -0.8 -3.0 Type VI secretion lipoprotein/VasD compare
Pf6N2E2_5877 -0.8 -1.9 Phosphohistidine phosphatase SixA compare
Pf6N2E2_5243 -0.8 -1.6 hypothetical protein compare
Pf6N2E2_1705 -0.7 -1.4 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_3206 -0.7 -1.3 hypothetical protein compare
Pf6N2E2_5573 -0.7 -3.0 Glycerol-3-phosphate regulon repressor, DeoR family compare
Pf6N2E2_3847 -0.7 -2.2 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_4824 -0.7 -2.0 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_5848 -0.7 -2.4 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf6N2E2_290 -0.7 -2.1 Cold shock protein CspD compare
Pf6N2E2_3040 -0.7 -3.9 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_1838 -0.7 -2.5 6-hexanolactone hydrolase compare
Pf6N2E2_4636 -0.7 -4.3 periplasmic binding protein, putative compare
Pf6N2E2_3039 -0.7 -4.2 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_3807 -0.7 -2.4 Histidine utilization repressor compare
Pf6N2E2_961 -0.7 -2.1 FIG00954712: hypothetical protein compare
Pf6N2E2_70 -0.7 -2.7 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_3532 -0.7 -3.9 Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) compare
Pf6N2E2_2373 -0.7 -1.8 Type III secretion thermoregulatory protein (LcrF,VirF,transcription regulation of virulence plasmid) compare
Pf6N2E2_3062 -0.7 -2.9 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2309 -0.7 -2.2 hypothetical protein compare
Pf6N2E2_2390 -0.7 -1.1 FIG00959101: hypothetical protein compare
Pf6N2E2_2156 -0.7 -1.6 Putative polyketide synthase (Fragment) compare
Pf6N2E2_4359 -0.7 -2.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_893 -0.7 -1.8 hypothetical protein compare
Pf6N2E2_5328 -0.7 -2.9 FIG00958649: hypothetical protein compare
Pf6N2E2_3255 -0.7 -2.3 YrbA protein compare
Pf6N2E2_3762 -0.7 -3.7 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_2061 -0.7 -2.2 CobW GTPase involved in cobalt insertion for B12 biosynthesis compare
Pf6N2E2_4742 -0.7 -1.7 Glutathione S-transferase family protein compare
Pf6N2E2_4360 -0.7 -4.5 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_5738 -0.7 -4.1 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_1543 -0.7 -2.8 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_5679 -0.7 -2.7 hypothetical protein compare
Pf6N2E2_3077 -0.6 -1.6 FIG138056: a glutathione-dependent thiol reductase compare


Specific Phenotypes

None in this experiment

For Pseudomonas fluorescens FW300-N2E2 in carbon source experiments

For carbon source Sodium L-Lactate across organisms