Experiment set1IT007 for Pseudomonas fluorescens FW300-N2E2

Compare to:

a-Ketoglutaric acid disodium salt hydrate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4596 -6.7 -4.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4826 -6.6 -4.6 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_64 -6.6 -4.5 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4597 -6.5 -6.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3842 -6.3 -4.4 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3751 -6.2 -9.4 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3630 -6.0 -5.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4825 -5.9 -7.1 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_71 -5.8 -5.7 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3839 -5.6 -3.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3610 -5.5 -6.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_5252 -5.5 -3.8 FIG00956396: hypothetical protein compare
Pf6N2E2_5175 -5.4 -13.1 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3763 -5.4 -3.7 hypothetical protein compare
Pf6N2E2_3752 -5.4 -19.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3841 -5.3 -3.7 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3253 -5.3 -6.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4564 -5.2 -10.6 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3782 -5.1 -5.0 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4047 -5.0 -3.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_2277 -4.8 -3.3 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5488 -4.7 -15.7 C4-dicarboxylate transport sensor protein conserved
Pf6N2E2_4048 -4.7 -8.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_77 -4.7 -5.5 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3783 -4.7 -6.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3932 -4.6 -6.8 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_5486 -4.6 -17.2 Alpha-ketoglutarate permease (from data) conserved
Pf6N2E2_5487 -4.5 -4.8 Nitrogen regulation protein NR(I) conserved
Pf6N2E2_5177 -4.5 -11.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_5176 -4.4 -10.9 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_50 -4.3 -8.6 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_66 -4.3 -9.8 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_2073 -4.3 -6.5 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_2074 -4.1 -2.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3762 -4.1 -7.3 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_302 -4.1 -7.8 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3252 -4.0 -9.2 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3251 -4.0 -11.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_127 -3.9 -2.7 AttE component of AttEFGH ABC transport system compare
Pf6N2E2_3940 -3.8 -10.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4638 -3.8 -3.6 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_4204 -3.4 -2.3 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_5156 -3.4 -3.3 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2465 -3.3 -7.6 Cys regulon transcriptional activator CysB compare
Pf6N2E2_63 -3.2 -4.7 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_5006 -3.0 -8.1 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_5676 -3.0 -5.0 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5579 -2.9 -7.7 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4759 -2.8 -13.6 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3170 -2.7 -6.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_3248 -2.7 -5.7 Probable transmembrane protein compare
Pf6N2E2_2514 -2.6 -5.0 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_4009 -2.6 -8.9 GGDEF domain protein compare
Pf6N2E2_5728 -2.6 -3.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_5527 -2.5 -3.0 Cold shock protein CspC compare
Pf6N2E2_5666 -2.3 -8.6 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_51 -2.2 -6.9 hypothetical protein compare
Pf6N2E2_3349 -2.1 -3.6 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_4764 -2.1 -5.1 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_3984 -2.0 -9.5 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_3835 -2.0 -3.7 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5667 -2.0 -5.1 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_4454 -1.9 -5.5 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_2753 -1.9 -3.8 HtrA protease/chaperone protein compare
Pf6N2E2_2286 -1.9 -2.5 FIG00953287: hypothetical protein compare
Pf6N2E2_2217 -1.9 -5.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4631 -1.9 -7.7 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_2473 -1.8 -1.8 Major outer membrane lipoprotein I compare
Pf6N2E2_5258 -1.8 -7.1 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4372 -1.8 -4.9 FIG00460773: hypothetical protein compare
Pf6N2E2_5316 -1.8 -1.7 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_178 -1.7 -1.5 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_4761 -1.7 -6.8 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_2258 -1.7 -6.9 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_2064 -1.6 -3.3 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_3326 -1.6 -2.5 hypothetical protein compare
Pf6N2E2_5936 -1.6 -2.5 Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) compare
Pf6N2E2_5950 -1.6 -4.0 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2218 -1.6 -4.2 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_5219 -1.6 -7.6 FIG140336: TPR domain protein compare
Pf6N2E2_2312 -1.6 -2.3 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_4763 -1.5 -6.4 Biotin synthesis protein BioC compare
Pf6N2E2_3938 -1.5 -7.3 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3134 -1.5 -1.3 hypothetical protein compare
Pf6N2E2_5669 -1.5 -5.5 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_5014 -1.5 -1.5 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3346 -1.5 -4.4 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_5257 -1.4 -6.3 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_4624 -1.4 -1.3 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf6N2E2_5553 -1.4 -6.4 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_5081 -1.4 -3.2 hypothetical protein compare
Pf6N2E2_3198 -1.4 -2.0 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_4153 -1.4 -1.3 Sensory box histidine kinase compare
Pf6N2E2_5001 -1.4 -2.4 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_3062 -1.4 -2.4 Membrane-associated zinc metalloprotease compare
Pf6N2E2_248 -1.4 -5.7 hypothetical protein compare
Pf6N2E2_1705 -1.4 -1.9 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_5841 -1.3 -1.5 GlcG protein compare
Pf6N2E2_3534 -1.3 -1.8 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_3461 -1.3 -1.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_4562 -1.3 -3.1 L-cystine uptake protein TcyP compare
Pf6N2E2_4416 -1.3 -1.9 Tyrosine recombinase XerC compare
Pf6N2E2_5584 -1.3 -2.1 Bacterioferritin-associated ferredoxin compare
Pf6N2E2_4317 -1.3 -2.5 FIG00964469: hypothetical protein compare
Pf6N2E2_5671 -1.3 -3.4 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_579 -1.3 -2.1 FIG00962753: hypothetical protein compare
Pf6N2E2_4762 -1.2 -2.0 Biotin synthesis protein BioH compare
Pf6N2E2_3696 -1.2 -1.2 hypothetical protein compare
Pf6N2E2_5207 -1.2 -1.8 hypothetical protein compare
Pf6N2E2_3899 -1.2 -4.9 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_2390 -1.2 -3.0 FIG00959101: hypothetical protein compare
Pf6N2E2_3537 -1.2 -2.9 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_4417 -1.2 -2.3 Protein of unknown function DUF484 compare
Pf6N2E2_4205 -1.1 -2.8 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_2367 -1.1 -1.8 hypothetical protein compare
Pf6N2E2_1173 -1.1 -1.8 hypothetical protein compare
Pf6N2E2_5520 -1.1 -4.0 Sensory box histidine kinase compare
Pf6N2E2_4710 -1.0 -1.1 hypothetical protein compare
Pf6N2E2_3255 -1.0 -2.1 YrbA protein compare
Pf6N2E2_2574 -1.0 -2.0 Flagellar synthesis regulator FleN compare
Pf6N2E2_5468 -1.0 -2.6 Nudix hydrolase family protein PA3470 compare
Pf6N2E2_5331 -1.0 -4.1 ATPase, AFG1 family compare
Pf6N2E2_3226 -1.0 -2.3 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_613 -1.0 -1.5 lipoprotein, putative compare
Pf6N2E2_4797 -1.0 -1.3 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_2013 -0.9 -1.1 hypothetical protein compare
Pf6N2E2_70 -0.9 -2.5 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_1792 -0.9 -2.4 Hydroxypyruvate isomerase (EC 5.3.1.22) compare
Pf6N2E2_2984 -0.9 -1.6 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_1667 -0.9 -1.3 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_4039 -0.9 -3.7 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf6N2E2_5665 -0.9 -3.8 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_1691 -0.9 -1.2 hypothetical protein compare
Pf6N2E2_5342 -0.9 -1.7 21 kDa hemolysin precursor compare
Pf6N2E2_3557 -0.9 -2.3 Chaperone-modulator protein CbpM compare
Pf6N2E2_5806 -0.9 -1.1 hypothetical protein compare
Pf6N2E2_4824 -0.9 -2.4 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_939 -0.9 -2.6 hypothetical protein compare
Pf6N2E2_3883 -0.9 -2.8 C4-dicarboxylate transport transcriptional regulatory protein compare
Pf6N2E2_2012 -0.9 -2.0 hypothetical protein compare
Pf6N2E2_1932 -0.9 -3.4 Transcriptional regulator, IclR family compare
Pf6N2E2_1400 -0.9 -5.7 Sensory box histidine kinase/response regulator compare
Pf6N2E2_1886 -0.9 -1.3 hypothetical protein compare
Pf6N2E2_4181 -0.9 -1.1 Organic hydroperoxide resistance protein compare
Pf6N2E2_2282 -0.9 -2.4 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_5738 -0.9 -4.4 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_5111 -0.9 -1.9 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_3039 -0.9 -3.0 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_624 -0.9 -3.1 hypothetical protein PA3071 compare
Pf6N2E2_5345 -0.8 -4.3 LppC putative lipoprotein compare
Pf6N2E2_3869 -0.8 -4.2 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_3535 -0.8 -3.0 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
Pf6N2E2_3505 -0.8 -1.1 Translation initiation factor SUI1-related protein compare
Pf6N2E2_2065 -0.8 -2.0 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_1718 -0.8 -2.1 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_4072 -0.8 -2.3 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_2081 -0.8 -1.3 putative exported protein compare
Pf6N2E2_4747 -0.8 -1.2 Transmembrane sensor compare
Pf6N2E2_3271 -0.8 -2.0 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_2758 -0.8 -6.0 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_3466 -0.8 -1.8 FIG000605: protein co-occurring with transport systems (COG1739) compare
Pf6N2E2_971 -0.8 -1.8 hypothetical protein compare
Pf6N2E2_199 -0.8 -2.1 hypothetical protein compare
Pf6N2E2_4392 -0.8 -1.7 Translation initiation inhibitor compare
Pf6N2E2_2646 -0.8 -1.2 FIG00953416: hypothetical protein compare
Pf6N2E2_2488 -0.8 -1.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4038 -0.8 -4.2 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf6N2E2_65 -0.8 -1.9 SAM-dependent methyltransferase YafE (UbiE paralog) compare
Pf6N2E2_2886 -0.8 -5.8 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_5157 -0.8 -4.8 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_122 -0.8 -1.3 Tyrosine-protein kinase Wzc (EC 2.7.10.2) compare
Pf6N2E2_1313 -0.8 -1.7 2-oxo-hepta-3-ene-1,7-dioic acid hydratase (EC 4.2.-.-) compare
Pf6N2E2_3533 -0.8 -2.4 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_495 -0.8 -1.9 YD repeat protein compare
Pf6N2E2_5406 -0.8 -1.4 FIG00958224: hypothetical protein compare
Pf6N2E2_3027 -0.8 -1.1 Baseplate assembly protein V compare
Pf6N2E2_1325 -0.8 -1.7 FIG00954773: hypothetical protein compare
Pf6N2E2_374 -0.7 -2.4 FIG00953249: hypothetical protein compare
Pf6N2E2_2794 -0.7 -1.2 putative membrane protein compare
Pf6N2E2_5425 -0.7 -1.0 hypothetical protein compare
Pf6N2E2_99 -0.7 -2.4 hypothetical protein compare
Pf6N2E2_2061 -0.7 -2.0 CobW GTPase involved in cobalt insertion for B12 biosynthesis compare
Pf6N2E2_4040 -0.7 -5.7 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) compare
Pf6N2E2_4364 -0.7 -1.2 Protein YicC compare
Pf6N2E2_2068 -0.7 -3.7 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_432 -0.7 -3.7 Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1) compare
Pf6N2E2_311 -0.7 -2.4 hypothetical protein compare
Pf6N2E2_1839 -0.7 -1.9 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase (EC 1.1.1.-) compare
Pf6N2E2_1456 -0.7 -3.0 D-xylose transport ATP-binding protein XylG compare
Pf6N2E2_2693 -0.7 -1.2 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_4071 -0.7 -1.8 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4273 -0.7 -3.3 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_3826 -0.7 -2.6 Nitrogen regulation protein NR(I) compare
Pf6N2E2_5723 -0.7 -4.2 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_1709 -0.7 -1.8 multidrug resistance transporter, Bcr/CflA family compare
Pf6N2E2_1834 -0.7 -1.1 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_4749 -0.7 -1.7 DNA polymerase III epsilon subunit (EC 2.7.7.7) compare
Pf6N2E2_5242 -0.7 -1.1 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_3199 -0.7 -3.3 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
Pf6N2E2_1339 -0.7 -1.8 Acetylornithine deacetylase (EC 3.5.1.16) compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source a-Ketoglutaric acid disodium salt hydrate in Pseudomonas fluorescens FW300-N2E2

For carbon source a-Ketoglutaric acid disodium salt hydrate across organisms