Experiment set1IT007 for Sinorhizobium meliloti 1021

Compare to:

D-Xylose carbon source

200 most important genes:

  gene name fitness t score description  
SMc02572 -10.1 -6.6 imidazole glycerol phosphate synthase subunit HisH compare
SMc02899 -8.6 -6.0 prephenate dehydratase compare
SMc01726 -8.6 -6.0 acetylglutamate kinase compare
SMc01843 -8.6 -5.9 5,10-methylenetetrahydrofolate reductase compare
SMc02767 -8.6 -5.9 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc02245 -8.1 -5.6 dihydroorotate dehydrogenase 2 compare
SMc00235 -8.1 -5.6 anthranilate phosphoribosyltransferase compare
SMc01494 -8.0 -9.5 phosphoserine phosphatase compare
SMc00236 -8.0 -5.5 Indole-3-glycerol phosphate synthase compare
SMc02766 -8.0 -10.9 tryptophan synthase subunit beta compare
SMc03797 -8.0 -7.8 homoserine O-succinyltransferase compare
SMc01054 -7.8 -5.4 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc02569 -7.7 -5.3 imidazole glycerol phosphate synthase subunit HisF compare
SMc02717 -7.7 -5.3 2-isopropylmalate synthase compare
SMc01801 -7.7 -5.1 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc04405 -7.7 -9.1 3-isopropylmalate dehydrogenase compare
SMc00640 -7.6 -7.4 phosphoserine aminotransferase compare
SMc02725 -7.5 -9.0 anthranilate synthase compare
SMc04045 -7.4 -5.1 dihydroxy-acid dehydratase compare
SMc04026 -7.4 -8.8 glutamate synthase compare
SMc03823 -7.3 -12.7 isopropylmalate isomerase large subunit compare
SMc02765 -7.2 -13.3 tryptophan synthase subunit alpha compare
SMc02137 -7.1 -4.9 ornithine carbamoyltransferase compare
SMc02123 -7.1 -3.9 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc01431 -7.0 -9.6 acetolactate synthase 3 catalytic subunit compare
SMc04028 -7.0 -13.4 glutamate synthase compare
SMc00993 -6.9 -9.4 phosphoribosylamine--glycine ligase compare
SMc00711 -6.7 -6.6 cyclohexadienyl dehydrogenase compare
SM_b21176 -6.7 -4.6 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc00918 -6.6 -10.2 ATP phosphoribosyltransferase regulatory subunit compare
SM_b21175 -6.6 -5.1 phosphate uptake ABC transporter permease compare
SMc00493 -6.6 -6.5 phosphoribosylformylglycinamidine synthase I compare
SMc02217 -6.6 -6.4 O-succinylhomoserine sulfhydrylase compare
SMc00488 -6.6 -19.0 phosphoribosylformylglycinamidine synthase II compare
SMa1635 -6.5 -2.5 hypothetical protein compare
SMc03112 -6.4 -18.0 B12-dependent methionine synthase compare
SMc03776 -6.4 -4.4 gamma-glutamyl kinase compare
SMc00495 -6.4 -5.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc03070 -6.3 -7.5 glucose-6-phosphate 1-dehydrogenase compare
SMc00293 -6.3 -14.0 homoserine dehydrogenase compare
SMc01360 -6.1 -4.2 aspartate carbamoyltransferase catalytic subunit compare
SMc02165 -6.0 -8.3 orotate phosphoribosyltransferase compare
SMc00554 -6.0 -9.2 amidophosphoribosyltransferase compare
SMc01004 -6.0 -9.0 phosphoribosyl-AMP cyclohydrolase compare
SMc00917 -6.0 -6.1 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc00412 -5.8 -5.7 orotidine 5'-phosphate decarboxylase compare
SMc00615 -5.8 -9.7 phosphoribosylaminoimidazole synthetase compare
SMc04002 -5.8 -5.8 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc03777 -5.7 -9.6 gamma-glutamyl phosphate reductase compare
SMc00090 -5.7 -13.9 sulfate adenylyltransferase compare
SMc02755 -5.7 -6.8 S-adenosyl-L-homocysteine hydrolase compare
SMc01361 -5.7 -6.5 dihydroorotase compare
SMc02707 -5.6 -6.3 hypothetical protein compare
SM_b21177 -5.5 -9.2 phosphate uptake ABC transporter ATP-binding protein compare
SMc00815 -5.5 -3.6 inosine 5'-monophosphate dehydrogenase compare
SMc03229 -5.5 -3.7 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc03895 -5.5 -19.9 pyruvate carboxylase compare
SMc00131 -5.4 -15.2 transcriptional regulator compare
SMc03979 -5.2 -3.6 glyceraldehyde-3-phosphate dehydrogenase compare
SMc02124 -5.2 -15.1 nitrite reductase compare
SMc04088 -5.1 -8.2 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc00092 -5.0 -13.1 phosphoadenosine phosphosulfate reductase compare
SMc00494 -5.0 -2.7 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc03978 -4.9 -3.4 transketolase compare
SMc03826 -4.8 -5.7 argininosuccinate synthase compare
SMc01215 -4.8 -3.3 carbamoyl phosphate synthase large subunit compare
SMc02166 -4.8 -11.4 dihydroorotase compare
SMc01881 -4.8 -4.6 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc01569 -4.7 -2.5 carbamoyl phosphate synthase small subunit compare
SMc00614 -4.7 -6.7 phosphoribosylglycinamide formyltransferase compare
SMc01880 -4.6 -4.5 pantoate--beta-alanine ligase compare
SMc03763 -4.5 -4.4 cytosine-specific methyltransferase compare
SMc02574 -4.5 -6.2 imidazoleglycerol-phosphate dehydratase compare
SMc00294 -4.5 -10.0 aminotransferase compare
SMc01053 -4.5 -5.9 siroheme synthase compare
SMc00091 -4.4 -14.5 sulfate adenylyltransferase compare
SMc04001 -4.4 -1.7 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc01770 -4.4 -2.0 serine hydroxymethyltransferase compare
SMc02138 -4.4 -5.4 acetylornithine transaminase compare
SMc02570 -4.3 -4.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc02495 -4.3 -2.2 translaldolase compare
SMc00876 -4.3 -8.2 ATP-binding MRP protein compare
SMc00017 -4.3 -2.3 homoserine kinase compare
SMc02246 -4.2 -1.6 hypothetical protein compare
SMc00511 -4.2 -6.3 D-ribulose-5-phosphate 3-epimerase compare
SMc03795 -4.2 -2.3 isopropylmalate isomerase small subunit compare
SMc02307 -4.1 -10.2 histidinol dehydrogenase compare
SMc00334 -4.1 -3.4 cytidylate kinase compare
SMc03164 -3.9 -13.6 Xylulose kinase (EC 2.7.1.17) (from data) conserved
SMc00641 -3.9 -6.3 D-3-phosphoglycerate dehydrogenase compare
SMc03981 -3.7 -3.5 phosphoglycerate kinase compare
SM_b21174 -3.6 -5.4 phosphate uptake ABC transporter permease compare
SMc03163 -3.5 -12.1 Xylose isomerase (EC 5.3.1.5) (from data) conserved
SMc03165 -3.5 -7.3 Novel Xylose regulator from LacI family (from data) conserved
SMc00414 -3.4 -11.3 hypothetical protein compare
SMc04346 -3.3 -4.6 ketol-acid reductoisomerase compare
SMc04330 -3.3 -3.0 trimethylamine methyltransferase compare
SMc04005 -3.2 -9.1 pyruvate kinase compare
SMc01028 -3.2 -15.2 phosphopyruvate hydratase compare
SMc02833 -3.2 -3.7 penicillin-insensitive murein endopeptidase compare
SMc02425 -3.1 -6.2 transcriptional regulator compare
SMc01206 -3.0 -3.2 queuine tRNA-ribosyltransferase compare
SMc02058 -2.9 -4.1 YAJC protein compare
SMc03068 -2.8 -11.4 phosphogluconate dehydratase compare
SMc02983 -2.7 -8.4 ornithine, DAP, or arginine decarboxylase compare
SMc01124 -2.7 -7.9 PII uridylyl-transferase compare
SMc00982 -2.7 -6.9 dioxygenase compare
SMc00963 -2.7 -4.0 hypothetical protein compare
SMc01578 -2.6 -13.3 aspartate aminotransferase compare
SMc01147 -2.6 -4.2 coproporphyrinogen III oxidase compare
SMc02838 -2.2 -6.7 phosphoglyceromutase compare
SM_b20902 -2.2 -12.8 sugar uptake ABC transporter substrate-binding protein precursor compare
SMc01440 -2.1 -4.7 hydrolase serine protease transmembrane protein compare
SM_b20903 -2.1 -7.7 sugar uptake ABC transporter permease compare
SMc01430 -2.0 -4.0 acetolactate synthase 3 regulatory subunit compare
SM_b20904 -2.0 -4.5 sugar uptake ABC transporter ATP-binding protein compare
SMc02640 -1.9 -5.5 UDP-glucuronic acid epimerase compare
SMc02719 -1.9 -1.4 transposase compare
SMc03100 -1.9 -1.7 hypothetical protein compare
SM_b20086 -1.9 -1.6 hypothetical protein compare
SMc00295 -1.8 -1.2 hypothetical protein compare
SMc01441 -1.7 -5.6 membrane bound protease compare
SMc04296 -1.7 -1.0 cell division protein FtsZ compare
SMc03053 -1.6 -2.1 flagellar biosynthesis protein FliQ compare
SMc02505 -1.6 -2.1 hypothetical protein compare
SMc02451 -1.5 -2.3 hypothetical protein compare
SMc02659 -1.5 -5.7 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc00838 -1.4 -5.0 hypothetical protein compare
SMc02753 -1.4 -1.7 PTS system transporter subunit IIA compare
SMc01119 -1.4 -2.6 hypothetical protein compare
SMc02685 -1.4 -3.5 hypothetical protein compare
SMc03069 -1.3 -2.4 6-phosphogluconolactonase compare
SMc01501 -1.3 -1.8 mannitol 2-dehydrogenase compare
SMa1052 -1.3 -1.9 hypothetical protein compare
SMc00914 -1.3 -3.0 oxidoreductase compare
SMc01208 -1.3 -2.5 peptidyl-prolyl cis-trans isomerase B protein compare
SMa0326 -1.3 -1.8 short chain alcohol dehydrogenase-related dehydrogenase compare
SM_b20897 -1.3 -2.3 hypothetical protein compare
SMc04348 -1.2 -1.3 transcriptional regulator compare
SMc01850 -1.2 -3.0 hypothetical protein compare
SMc02227 -1.2 -5.4 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMa0789 -1.2 -2.7 GntR family transcriptional regulator compare
SMc00928 -1.2 -1.4 signal peptide protein compare
SM_b20323 -1.2 -1.2 transcriptional regulator compare
SMc03153 -1.1 -3.3 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase compare
SMa1101 -1.1 -1.4 hypothetical protein compare
SMc00012 -1.1 -1.1 cytochrome C oxidase assembly protein compare
SM_b20728 -1.1 -1.6 hypothetical protein compare
SMc00821 -1.1 -1.6 hypothetical protein compare
SMc01368 -1.1 -4.3 transport transmembrane protein compare
SMc02724 -1.1 -2.6 hypothetical protein compare
SMc01207 -1.1 -2.3 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc02121 -1.1 -1.8 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component (from data) compare
SMc00361 -1.1 -2.2 hypothetical protein compare
SMc03980 -1.1 -3.3 hypothetical protein compare
SMc00981 -1.1 -4.8 ferredoxin protein compare
SM_b20955 -1.0 -3.7 endo-beta-1,3-1,4-glycanase compare
SMc02147 -1.0 -4.6 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc01495 -1.0 -3.3 transcriptional regulator compare
SMc01845 -1.0 -1.8 transglycosylase transmembrane protein compare
SMc02641 -1.0 -3.1 UDP-glucose 6-dehydrogenase compare
SMc00450 -1.0 -1.7 protoheme IX farnesyltransferase compare
SMc02149 -1.0 -1.8 hypothetical protein compare
SMc04242 -1.0 -1.8 zinc uptake regulation protein compare
SMa5033 -1.0 -1.0 hypothetical protein compare
SMc02886 -1.0 -2.1 signal peptide protein compare
SMc00302 -1.0 -2.8 hypothetical protein compare
SM_b21035 -0.9 -4.4 hypothetical protein compare
SMa2020 -0.9 -3.1 Transcriptional regulator compare
SM_b20258 -0.9 -2.0 transcriptional regulator compare
SMc00053 -0.9 -0.8 monovalent cation/H+ antiporter subunit C compare
SMc04000 -0.9 -0.7 hypothetical protein compare
SMc03140 -0.9 -3.4 transcriptional regulator compare
SM_b21112 -0.9 -4.3 L-2,4-diketo-3-deoxyrhamnonate hydrolase; 2,4-dioxopentanoate hydrolase (from data) compare
SMc00288 -0.9 -4.7 signal peptide protein compare
SMc02856 -0.9 -5.6 penicillin-binding protein compare
SM_b20953 -0.9 -1.0 hypothetical protein compare
SMc00709 -0.9 -2.4 hypothetical protein compare
SMc01842 -0.9 -0.9 methyltransferase transcription regulator protein compare
SM_b20294 -0.9 -1.1 transcriptional regulator NanR compare
SMc00060 -0.9 -5.2 hypothetical protein compare
SMc02308 -0.9 -2.3 hypothetical protein compare
SM_b22001 -0.9 -1.3 hypothetical protein compare
SM_b20413 -0.9 -1.0 hypothetical protein compare
SMc02362 -0.9 -2.6 cytochrome c-type biogenesis protein CcmE compare
SMc00405 -0.9 -4.5 hypothetical protein compare
SMc04357 -0.9 -1.5 hypothetical protein compare
SMa0112 -0.9 -1.6 hypothetical protein compare
SMc00689 -0.9 -3.1 lipoprotein compare
SMc03774 -0.9 -2.0 hypothetical protein compare
SMc01216 -0.9 -2.1 hypothetical protein compare
SMc01858 -0.8 -1.2 S-adenosyl-methyltransferase MraW compare
SMc02812 -0.8 -2.2 hypothetical protein compare
SMc01622 -0.8 -4.4 oxidoreductase compare
SM_b21131 -0.8 -5.1 sulfate ABC transporter permease compare
SM_b20226 -0.8 -1.5 hypothetical protein compare
SMc01709 -0.8 -1.7 signal peptide protein compare
SM_b20148 -0.8 -3.7 transcriptional regulator compare
SMc02385 -0.8 -2.0 hypothetical protein compare
SMc02229 -0.8 -5.8 acyl-CoA dehydrogenase compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source D-Xylose in Sinorhizobium meliloti 1021

For carbon source D-Xylose across organisms