Experiment set1IT001 for Pseudomonas fluorescens FW300-N2E2

Compare to:

D-Glucose carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3248 -7.0 -4.9 Probable transmembrane protein compare
Pf6N2E2_5006 -6.6 -4.6 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_64 -6.4 -4.4 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3842 -6.2 -4.3 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4597 -6.1 -7.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_71 -6.1 -4.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_5177 -5.8 -8.0 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3630 -5.8 -5.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5175 -5.8 -8.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4596 -5.8 -8.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3839 -5.4 -3.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_5150 -5.4 -3.7 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_4826 -5.4 -7.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3751 -5.4 -12.0 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3782 -5.3 -5.2 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3783 -5.2 -6.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_77 -5.1 -5.0 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3253 -5.1 -6.1 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_2885 -5.1 -3.5 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_5176 -5.0 -9.1 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4048 -4.9 -7.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_2258 -4.9 -8.8 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4825 -4.9 -8.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3610 -4.8 -6.4 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_2863 -4.8 -7.3 Gluconate permease compare
Pf6N2E2_3841 -4.7 -4.6 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3940 -4.7 -10.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5527 -4.6 -3.1 Cold shock protein CspC compare
Pf6N2E2_302 -4.5 -6.9 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4762 -4.5 -4.2 Biotin synthesis protein BioH compare
Pf6N2E2_3752 -4.5 -20.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4564 -4.4 -9.2 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_66 -4.3 -9.2 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4279 -4.3 -12.8 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4362 -4.3 -5.1 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_4764 -4.2 -6.2 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_4278 -4.2 -10.6 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_2073 -4.2 -7.0 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_2753 -4.0 -3.8 HtrA protease/chaperone protein compare
Pf6N2E2_4759 -3.8 -15.1 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_5728 -3.7 -5.6 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_3461 -3.7 -2.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_3252 -3.6 -8.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3460 -3.6 -2.5 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3932 -3.6 -6.1 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_2899 -3.6 -5.5 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_4047 -3.5 -6.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4277 -3.5 -9.5 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_5579 -3.5 -9.6 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4276 -3.5 -5.3 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_3346 -3.4 -6.8 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_50 -3.2 -8.1 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_63 -3.1 -5.7 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4638 -3.1 -4.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2693 -3.1 -1.5 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_3534 -3.0 -2.8 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_5156 -2.9 -3.4 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2465 -2.8 -5.7 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3170 -2.8 -7.1 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_4761 -2.8 -8.7 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_4763 -2.8 -8.1 Biotin synthesis protein BioC compare
Pf6N2E2_3251 -2.8 -9.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_5316 -2.6 -2.9 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_2588 -2.5 -3.8 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_4631 -2.5 -9.6 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_4187 -2.5 -2.9 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3984 -2.4 -9.9 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_2261 -2.3 -7.5 VacJ-like lipoprotein precursor compare
Pf6N2E2_3260 -2.3 -5.8 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_3264 -2.2 -3.0 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4009 -2.2 -7.1 GGDEF domain protein compare
Pf6N2E2_2938 -2.2 -5.2 Outer membrane lipoprotein compare
Pf6N2E2_4071 -2.1 -3.8 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_3835 -2.0 -3.0 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3505 -2.0 -2.3 Translation initiation factor SUI1-related protein compare
Pf6N2E2_3825 -2.0 -4.9 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_4416 -2.0 -2.9 Tyrosine recombinase XerC compare
Pf6N2E2_5086 -2.0 -1.7 hypothetical protein compare
Pf6N2E2_3770 -2.0 -2.9 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_3171 -1.9 -1.7 hypothetical protein compare
Pf6N2E2_3257 -1.9 -3.9 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_4372 -1.9 -4.8 FIG00460773: hypothetical protein compare
Pf6N2E2_3258 -1.8 -4.7 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_3826 -1.8 -4.8 Nitrogen regulation protein NR(I) compare
Pf6N2E2_5553 -1.8 -5.8 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_1396 -1.8 -3.1 ABC transporter, ATP-binding protein compare
Pf6N2E2_4453 -1.8 -11.8 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_3198 -1.8 -2.4 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_2758 -1.8 -9.9 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_5494 -1.8 -4.3 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_4803 -1.8 -1.5 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_51 -1.8 -4.7 hypothetical protein compare
Pf6N2E2_2218 -1.7 -4.2 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2574 -1.7 -2.3 Flagellar synthesis regulator FleN compare
Pf6N2E2_248 -1.7 -6.3 hypothetical protein compare
Pf6N2E2_1652 -1.7 -2.6 Transcriptional regulator, TetR family compare
Pf6N2E2_5103 -1.7 -1.9 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_5524 -1.7 -9.6 Outer membrane porin, OprD family compare
Pf6N2E2_3271 -1.6 -2.9 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_2217 -1.6 -4.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4611 -1.6 -3.4 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_5780 -1.6 -7.6 Periplasmic protease compare
Pf6N2E2_4797 -1.6 -1.9 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_4987 -1.6 -1.4 MaoC-like domain protein compare
Pf6N2E2_2074 -1.6 -1.2 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3060 -1.6 -2.7 Outer membrane protein H precursor compare
Pf6N2E2_4077 -1.6 -1.9 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_2186 -1.5 -4.5 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_4049 -1.5 -5.9 Glycine cleavage system transcriptional activator compare
Pf6N2E2_2897 -1.5 -7.0 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_2274 -1.5 -3.8 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_5676 -1.5 -3.7 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_658 -1.5 -6.0 sensor histidine kinase compare
Pf6N2E2_5001 -1.5 -2.3 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_546 -1.5 -1.6 FIG00966904: hypothetical protein compare
Pf6N2E2_1717 -1.5 -6.6 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_5219 -1.4 -5.4 FIG140336: TPR domain protein compare
Pf6N2E2_5520 -1.4 -4.4 Sensory box histidine kinase compare
Pf6N2E2_5160 -1.4 -1.9 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_2507 -1.4 -4.8 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_2852 -1.3 -6.7 GGDEF domain/EAL domain protein compare
Pf6N2E2_2518 -1.3 -1.4 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_2527 -1.3 -3.0 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_663 -1.3 -3.1 Transcriptional activator of acetoin dehydrogenase operon AcoR compare
Pf6N2E2_5723 -1.3 -7.0 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_5666 -1.3 -4.9 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_2891 -1.3 -6.7 Glucose ABC transport system, inner membrane component 1 compare
Pf6N2E2_3677 -1.2 -8.0 Sensory box/GGDEF family protein compare
Pf6N2E2_5667 -1.2 -4.2 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_4414 -1.2 -2.7 FIG00953808: hypothetical protein compare
Pf6N2E2_3938 -1.2 -6.6 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3072 -1.2 -6.8 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_939 -1.2 -2.1 hypothetical protein compare
Pf6N2E2_2473 -1.2 -1.3 Major outer membrane lipoprotein I compare
Pf6N2E2_2508 -1.2 -2.7 hypothetical protein compare
Pf6N2E2_1673 -1.2 -2.2 Transcriptional regulator, TetR family compare
Pf6N2E2_4579 -1.2 -1.4 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_5242 -1.2 -1.6 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2896 -1.2 -2.6 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
Pf6N2E2_1783 -1.2 -2.4 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_5078 -1.2 -2.3 Carbon starvation protein A compare
Pf6N2E2_1352 -1.2 -2.1 Cation transport ATPase compare
Pf6N2E2_4153 -1.2 -1.1 Sensory box histidine kinase compare
Pf6N2E2_2889 -1.2 -5.7 Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-) compare
Pf6N2E2_3847 -1.2 -2.9 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_4204 -1.2 -1.3 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_3568 -1.2 -1.5 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_3351 -1.2 -2.5 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_2111 -1.1 -2.6 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit A (from data) compare
Pf6N2E2_1611 -1.1 -3.6 Phosphonate ABC transporter permease protein phnE2 (TC 3.A.1.9.1) compare
Pf6N2E2_2155 -1.1 -3.1 hypothetical protein compare
Pf6N2E2_4417 -1.1 -2.4 Protein of unknown function DUF484 compare
Pf6N2E2_3338 -1.1 -1.8 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_97 -1.1 -3.5 putataive branched-chain amino acid transport protein AzlC compare
Pf6N2E2_2181 -1.1 -1.4 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_2702 -1.1 -3.7 FIG00962464: hypothetical protein compare
Pf6N2E2_4305 -1.1 -1.1 FIG00959590: hypothetical protein compare
Pf6N2E2_288 -1.1 -1.9 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_4205 -1.1 -2.8 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_1400 -1.1 -6.6 Sensory box histidine kinase/response regulator compare
Pf6N2E2_6100 -1.1 -1.8 tRNA-Val-TAC compare
Pf6N2E2_55 -1.0 -1.4 Probable hydrolase compare
Pf6N2E2_384 -1.0 -1.9 Glycine cleavage system transcriptional activator compare
Pf6N2E2_1859 -1.0 -1.6 hypothetical protein compare
Pf6N2E2_330 -1.0 -3.1 Mesenchymal stem cell protein DSCD75 compare
Pf6N2E2_1691 -1.0 -1.9 hypothetical protein compare
Pf6N2E2_178 -1.0 -1.0 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_4454 -1.0 -3.4 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_942 -1.0 -1.4 Mll6465 protein compare
Pf6N2E2_3373 -1.0 -1.0 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_504 -1.0 -1.6 DNA-binding response regulator compare
Pf6N2E2_2282 -1.0 -2.3 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_2973 -1.0 -3.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3638 -1.0 -1.6 hypothetical protein compare
Pf6N2E2_4352 -1.0 -2.0 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_2864 -1.0 -1.2 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_2681 -1.0 -3.1 3-phosphoglycerate kinase compare
Pf6N2E2_2367 -1.0 -1.9 hypothetical protein compare
Pf6N2E2_1625 -1.0 -2.2 Ferric reductase (1.6.99.14) compare
Pf6N2E2_3533 -1.0 -3.2 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_3349 -1.0 -1.4 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_625 -1.0 -2.3 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_622 -1.0 -3.1 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_2514 -1.0 -2.7 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_2252 -0.9 -2.4 NreA-like protein compare
Pf6N2E2_5584 -0.9 -1.4 Bacterioferritin-associated ferredoxin compare
Pf6N2E2_4545 -0.9 -1.5 hypothetical protein compare
Pf6N2E2_1718 -0.9 -2.2 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_5027 -0.9 -5.8 AMP nucleosidase (EC 3.2.2.4) compare
Pf6N2E2_5073 -0.9 -1.8 Large-conductance mechanosensitive channel compare
Pf6N2E2_5155 -0.9 -1.8 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_3833 -0.9 -3.5 hypothetical protein compare
Pf6N2E2_623 -0.9 -1.1 FIG00954674: hypothetical protein compare
Pf6N2E2_2285 -0.9 -1.4 FIG00954079: hypothetical protein compare
Pf6N2E2_5391 -0.9 -4.9 Predicted ATPase related to phosphate starvation-inducible protein PhoH compare
Pf6N2E2_3204 -0.9 -1.9 Rho-specific inhibitor of transcription termination (YaeO) compare
Pf6N2E2_1966 -0.9 -1.3 SAM-dependent methyltransferases compare
Pf6N2E2_2399 -0.9 -4.0 Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase compare
Pf6N2E2_1744 -0.9 -2.7 ABC transporter, periplasmic spermidine putrescine-binding protein PotD (TC 3.A.1.11.1) compare
Pf6N2E2_2166 -0.9 -4.3 protein of unknown function DUF6, transmembrane compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source D-Glucose in Pseudomonas fluorescens FW300-N2E2

For carbon source D-Glucose across organisms