Experiment set1H37 for Shewanella loihica PV-4

Compare to:

a-Ketoglutaric acid disodium salt hydrate carbon source

200 most detrimental genes:

  gene name fitness t score description  
Shew_1362 +6.1 21.8 sigma-54 dependent trancsriptional regulator (RefSeq) compare
Shew_1521 +5.8 10.4 OmpA/MotB domain-containing protein (RefSeq) compare
Shew_2767 motB +5.7 17.6 flagellar motor protein MotB (RefSeq) compare
Shew_2768 +5.7 30.1 flagellar motor protein PomA (RefSeq) compare
Shew_1370 +5.6 9.2 flagellar export protein FliJ (RefSeq) compare
Shew_1365 +5.5 14.8 flagellar hook-basal body complex subunit FliE (RefSeq) compare
Shew_1369 fliI +5.5 18.8 flagellum-specific ATP synthase (RefSeq) compare
Shew_1379 flhB +5.4 20.4 flagellar biosynthesis protein FlhB (RefSeq) compare
Shew_1350 flgG +5.4 27.0 flagellar basal body rod protein FlgG (RefSeq) compare
Shew_1349 flgF +5.4 29.0 flagellar basal body rod protein FlgF (RefSeq) compare
Shew_3290 +5.3 10.5 Sel1 domain-containing protein (RefSeq) compare
Shew_1348 flgE +5.3 31.4 flagellar hook protein FlgE (RefSeq) compare
Shew_1376 fliP +5.1 18.9 flagellar biosynthesis protein FliP (RefSeq) compare
Shew_1383 fliA +5.1 25.7 flagellar biosynthesis sigma factor (RefSeq) compare
Shew_1375 +5.1 36.6 flagellar biosynthesis protein, FliO (RefSeq) compare
Shew_1328 +4.9 22.6 acylneuraminate cytidylyltransferase (RefSeq) compare
Shew_1380 flhA +4.9 34.9 flagellar biosynthesis protein FlhA (RefSeq) compare
Shew_1347 flgD +4.8 15.9 flagellar basal body rod modification protein (RefSeq) compare
Shew_1352 flgI +4.8 20.9 flagellar basal body P-ring protein (RefSeq) compare
Shew_1371 +4.8 34.9 flagellar hook-length control protein (RefSeq) compare
Shew_1353 flgJ +4.7 6.7 peptidoglycan hydrolase (RefSeq) compare
Shew_1327 +4.7 25.3 hypothetical protein (RefSeq) compare
Shew_1361 fliS +4.7 28.2 flagellar protein FliS (RefSeq) compare
Shew_1319 +4.6 29.3 DegT/DnrJ/EryC1/StrS aminotransferase (RefSeq) compare
Shew_1354 +4.6 22.7 flagellar hook-associated protein FlgK (RefSeq) compare
Shew_1331 +4.6 22.4 spore coat polysaccharide biosynthesis protein glycosyltransferase-like (RefSeq) compare
Shew_1323 +4.6 15.3 acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II-like protein (RefSeq) compare
Shew_1318 +4.6 37.6 polysaccharide biosynthesis protein CapD (RefSeq) compare
Shew_1367 fliG +4.5 11.9 flagellar motor switch protein G (RefSeq) compare
Shew_1374 fliN +4.5 15.7 flagellar motor switch protein (RefSeq) compare
Shew_1366 fliF +4.5 21.0 flagellar MS-ring protein (RefSeq) compare
Shew_1340 +4.5 28.0 FlgN family protein (RefSeq) compare
Shew_1325 +4.4 31.2 acetyltransferase-like protein (RefSeq) compare
Shew_1329 +4.4 30.5 N-acylneuraminate-9-phosphate synthase (RefSeq) compare
Shew_1322 +4.4 21.9 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_1359 +4.3 22.3 flagellar hook-associated 2 domain-containing protein (RefSeq) compare
Shew_1334 +4.3 9.9 3-oxoacyl-(acyl-carrier-protein) synthase (RefSeq) compare
Shew_1355 flgL +4.3 19.8 flagellar hook-associated protein FlgL (RefSeq) compare
Shew_1368 +4.3 5.7 flagellar assembly protein FliH (RefSeq) compare
Shew_1324 +4.2 28.4 hypothetical protein (RefSeq) compare
Shew_1363 +4.0 26.7 PAS/PAC sensor signal transduction histidine kinase (RefSeq) compare
Shew_1332 +4.0 18.2 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_1372 fliL +3.9 12.8 flagellar basal body-associated protein FliL (RefSeq) compare
Shew_1333 +3.6 14.4 3-oxoacyl-(acyl-carrier-protein) synthase (RefSeq) compare
Shew_1364 +3.6 11.7 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_1357 +3.5 22.8 flagellin domain-containing protein (RefSeq) compare
Shew_1317 +3.4 22.1 TPR repeat-containing protein (RefSeq) compare
Shew_2480 +3.3 16.3 TonB-dependent receptor (RefSeq) compare
Shew_1373 fliM +3.2 11.1 flagellar motor switch protein FliM (RefSeq) compare
Shew_3689 +3.2 6.6 hypothetical protein (RefSeq) compare
Shew_1625 +2.5 6.4 L-serine dehydratase 1 (RefSeq) compare
Shew_2110 +2.5 14.7 hypothetical protein (RefSeq) compare
Shew_1058 +2.2 9.2 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_3440 +2.2 8.5 prepilin peptidase (RefSeq) compare
Shew_0395 +2.0 6.4 methylation site containing protein (RefSeq) compare
Shew_1341 +2.0 4.8 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_2421 +2.0 18.8 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) (RefSeq) compare
Shew_1337 +1.9 12.3 hypothetical protein (RefSeq) compare
Shew_3742 +1.9 15.6 flagellar basal body-associated protein FliL-like protein (RefSeq) compare
Shew_2010 +1.9 2.9 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_1326 +1.8 11.4 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_3682 +1.8 13.3 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_2837 +1.8 1.4 transcription elongation factor GreA (RefSeq) compare
Shew_1330 +1.7 4.8 Rieske (2Fe-2S) domain-containing protein (RefSeq) compare
Shew_2476 +1.6 2.6 MotA/TolQ/ExbB proton channel (RefSeq) compare
Shew_0777 +1.6 3.3 two-component response regulator (RefSeq) compare
Shew_3054 +1.5 2.6 hypothetical protein (RefSeq) compare
Shew_1078 +1.4 9.1 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_0330 +1.4 1.4 nifR3 family TIM-barrel protein (RefSeq) compare
Shew_3611 +1.4 2.7 general secretion pathway protein L (RefSeq) compare
Shew_0364 +1.4 1.6 MshA, mannose-sensitive haemaglutinin (RefSeq) compare
Shew_2459 +1.4 1.1 hypothetical protein (RefSeq) compare
Shew_0459 +1.4 4.2 PAS/PAC sensor hybrid histidine kinase (RefSeq) compare
Shew_3610 +1.3 1.5 general secretion pathway M protein (RefSeq) compare
Shew_3681 +1.3 4.8 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_0848 +1.2 1.2 hypothetical protein (RefSeq) compare
Shew_0470 +1.2 1.0 MATE efflux family protein (RefSeq) compare
Shew_1437 +1.2 5.5 transcriptional regulator, TyrR (RefSeq) compare
Shew_1925 +1.2 5.8 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (RefSeq) compare
Shew_1960 +1.2 1.1 hypothetical protein (RefSeq) compare
Shew_3063 +1.2 1.7 glycine cleavage system protein H (RefSeq) compare
Shew_2892 +1.1 3.5 major facilitator transporter (RefSeq) compare
Shew_1606 +1.1 1.0 hypothetical protein (RefSeq) compare
Shew_2409 +1.1 2.8 short chain dehydrogenase (RefSeq) compare
Shew_3612 +1.1 2.1 general secretion pathway protein K (RefSeq) compare
Shew_1392 +1.1 4.2 hypothetical protein (RefSeq) compare
Shew_3569 +1.0 2.2 protein of unknown function, Spy-related (RefSeq) compare
Shew_0618 +1.0 1.0 hypothetical protein (RefSeq) compare
Shew_1657 sucC +1.0 1.2 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_3710 tdh +1.0 7.2 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_1200 +1.0 3.1 hybrid sensory histidine kinase BarA (RefSeq) compare
Shew_0827 +1.0 1.0 peptidyl-prolyl cis-trans isomerase, cyclophilin type (RefSeq) compare
Shew_1397 +1.0 3.4 amino acid/peptide transporter (RefSeq) compare
Shew_1898 +1.0 1.5 ApbE family lipoprotein (RefSeq) compare
Shew_3696 +1.0 4.3 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase (RefSeq) compare
Shew_1011 +0.9 2.6 citrate transporter (RefSeq) compare
Shew_1391 +0.9 1.2 CheW protein (RefSeq) compare
Shew_1631 +0.9 2.1 hypothetical protein (RefSeq) compare
Shew_3434 +0.9 7.1 N-acetyl-anhydromuranmyl-L-alanine amidase (RefSeq) compare
Shew_2509 tig +0.9 4.4 trigger factor (RefSeq) compare
Shew_3436 +0.9 5.6 methylation site containing protein (RefSeq) compare
Shew_2890 +0.9 0.9 peptidyl-prolyl cis-trans isomerase, cyclophilin type (RefSeq) compare
Shew_3617 +0.9 0.8 general secretion pathway protein F (RefSeq) compare
Shew_2481 +0.9 2.5 porin (RefSeq) compare
Shew_2090 +0.8 1.3 methyl-accepting chemotaxis protein (RefSeq) compare
Shew_0914 +0.8 2.1 NADPH-dependent FMN reductase (RefSeq) compare
Shew_2528 +0.8 1.7 transcriptional regulator, CdaR (RefSeq) compare
Shew_2392 +0.8 1.7 hypothetical protein (RefSeq) compare
Shew_1864 +0.8 3.1 glucose-specific PTS system component (RefSeq) compare
Shew_0199 +0.8 2.5 hypothetical protein (RefSeq) compare
Shew_2643 +0.8 1.0 pseudouridylate synthase (RefSeq) compare
Shew_0121 +0.8 0.9 hypothetical protein (RefSeq) compare
Shew_0952 +0.8 1.3 peptidase M24 (RefSeq) compare
Shew_1223 +0.8 0.7 hypothetical protein (RefSeq) compare
Shew_2473 +0.8 1.3 tetratricopeptide domain-containing protein (RefSeq) compare
Shew_0730 +0.8 1.0 protein of unknown function DUF395, YeeE/YedE (RefSeq) compare
Shew_0102 +0.8 1.3 hypothetical protein (RefSeq) compare
Shew_1998 +0.8 2.0 protein of unknown function UPF0052 and CofD (RefSeq) compare
Shew_3275 +0.8 1.5 CheC domain-containing protein (RefSeq) compare
Shew_2407 +0.8 2.3 putative periplasmic protease (RefSeq) compare
Shew_1295 +0.8 1.4 hypothetical protein (RefSeq) compare
Shew_1927 +0.8 1.0 dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_2232 +0.8 1.8 heat shock protein 90 (RefSeq) compare
Shew_2754 +0.8 1.0 diguanylate cyclase (RefSeq) compare
Shew_3267 +0.8 2.3 sodium/hydrogen exchanger (RefSeq) compare
Shew_1386 +0.8 3.6 CheA signal transduction histidine kinase (RefSeq) compare
Shew_3049 +0.7 1.5 major facilitator transporter (RefSeq) compare
Shew_1048 +0.7 0.7 RNA polymerase sigma factor RpoE (RefSeq) compare
Shew_2906 +0.7 1.6 hypothetical protein (RefSeq) compare
Shew_1214 +0.7 2.9 DNA mismatch repair protein (RefSeq) compare
Shew_2246 +0.7 1.8 pseudouridine synthase (RefSeq) compare
Shew_2359 +0.7 0.6 uracil-DNA glycosylase superfamily protein (RefSeq) compare
Shew_2444 +0.7 1.0 hypothetical protein (RefSeq) compare
Shew_2520 +0.7 1.8 outer membrane protein, putative (RefSeq) compare
Shew_2795 +0.7 3.1 xanthine/uracil/vitamin C permease (RefSeq) compare
Shew_3622 hslO +0.7 2.7 Hsp33-like chaperonin (RefSeq) compare
Shew_0226 +0.7 1.0 hypothetical protein (RefSeq) compare
Shew_0319 cyaA +0.7 4.7 adenylate cyclase (RefSeq) compare
Shew_2219 +0.7 2.7 hypothetical protein (RefSeq) compare
Shew_2564 +0.7 1.9 MltA-interacting MipA family protein (RefSeq) compare
Shew_1035 +0.7 0.9 LysR family transcriptional regulator (RefSeq) compare
Shew_0564 +0.7 4.8 DNA mismatch repair protein MutL (RefSeq) compare
Shew_3423 +0.7 0.9 anti-RNA polymerase sigma 70 factor (RefSeq) compare
Shew_1076 +0.7 1.9 Trp operon repressor (RefSeq) compare
Shew_2450 +0.7 1.6 hypothetical protein (RefSeq) compare
Shew_2266 +0.7 2.0 2Fe-2S iron-sulfur cluster binding domain-containing protein (RefSeq) compare
Shew_1014 +0.7 0.6 XRE family transcriptional regulator (RefSeq) compare
Shew_0439 +0.7 1.7 CheD, stimulates methylation of MCP proteins (RefSeq) compare
Shew_1082 +0.7 1.0 hypothetical protein (RefSeq) compare
Shew_1439 +0.7 3.1 maleylacetoacetate isomerase (RefSeq) compare
Shew_2779 +0.7 1.9 amino acid ABC transporter (RefSeq) compare
Shew_0904 +0.7 1.4 GPR1/FUN34/yaaH family protein (RefSeq) compare
Shew_0584 +0.6 0.6 hypothetical protein (RefSeq) compare
Shew_0737 +0.6 3.6 MarR family transcriptional regulator (RefSeq) compare
Shew_0648 +0.6 1.6 hypothetical protein (RefSeq) compare
Shew_1773 +0.6 0.9 LysR family transcriptional regulator (RefSeq) compare
Shew_0383 +0.6 3.0 malate dehydrogenase (RefSeq) compare
Shew_2147 +0.6 0.8 hypothetical protein (RefSeq) compare
Shew_2011 +0.6 1.4 acriflavin resistance protein (RefSeq) compare
Shew_3709 +0.6 4.0 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_1432 +0.6 0.9 ferredoxin-type protein NapF (RefSeq) compare
Shew_0822 +0.6 2.0 lysine exporter protein LysE/YggA (RefSeq) compare
Shew_2456 +0.6 1.1 SMC domain-containing protein (RefSeq) compare
Shew_2403 +0.6 1.1 arylesterase (RefSeq) compare
Shew_2588 +0.6 1.3 putative lipoprotein (RefSeq) compare
Shew_0911 +0.6 1.0 hypothetical protein (RefSeq) compare
Shew_3618 +0.6 1.5 general secretory pathway protein E (RefSeq) compare
Shew_1903 +0.6 0.8 para-aminobenzoate synthase, subunit I (RefSeq) compare
Shew_2287 +0.6 1.8 galactokinase (RefSeq) compare
Shew_2243 +0.6 1.1 TraR/DksA family transcriptional regulator (RefSeq) compare
Shew_3528 +0.6 2.0 rhodanese domain-containing protein (RefSeq) compare
Shew_1694 +0.6 3.0 hypothetical protein (RefSeq) compare
Shew_2710 +0.6 2.6 O-acetylhomoserine/O-acetylserine sulfhydrylase (RefSeq) compare
Shew_0684 +0.6 1.4 hypothetical protein (RefSeq) compare
Shew_1083 +0.6 1.6 apurinic endonuclease Apn1 (RefSeq) compare
Shew_3786 +0.6 0.6 hypothetical protein (RefSeq) compare
Shew_3527 +0.6 1.2 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_1555 +0.6 1.0 Glu/Leu/Phe/Val dehydrogenase, dimerisation region (RefSeq) compare
Shew_1859 +0.6 0.6 carbonate dehydratase (RefSeq) compare
Shew_1077 +0.6 1.9 hypothetical protein (RefSeq) compare
Shew_0805 +0.6 1.2 hypothetical protein (RefSeq) compare
Shew_1978 +0.6 0.4 hypothetical protein (RefSeq) compare
Shew_1981 +0.6 1.6 AraC family transcriptional regulator (RefSeq) compare
Shew_2033 +0.6 1.0 hypothetical protein (RefSeq) compare
Shew_3246 +0.6 2.2 hypothetical protein (RefSeq) compare
Shew_1018 +0.6 1.1 hypothetical protein (RefSeq) compare
Shew_1686 +0.6 1.2 hypothetical protein (RefSeq) compare
Shew_0224 +0.6 2.0 transport-associated (RefSeq) compare
Shew_0097 +0.6 1.2 two component transcriptional regulator (RefSeq) compare
Shew_3201 +0.6 1.6 ABC transporter-related protein (RefSeq) compare
Shew_2860 +0.5 2.0 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_3483 dut +0.5 0.7 deoxyuridine 5'-triphosphate nucleotidohydrolase (RefSeq) compare
Shew_1815 +0.5 1.4 hypothetical protein (RefSeq) compare
Shew_0661 +0.5 0.5 hypothetical protein (RefSeq) compare
Shew_2270 +0.5 2.6 alpha/beta hydrolase fold (RefSeq) compare
Shew_1711 +0.5 0.8 methyl-accepting chemotaxis protein (RefSeq) compare
Shew_3064 gcvT +0.5 2.1 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_3718 +0.5 0.5 hypothetical protein (RefSeq) compare
Shew_3378 +0.5 0.4 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_0256 +0.5 1.2 hypothetical protein (RefSeq) compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source a-Ketoglutaric acid disodium salt hydrate in Shewanella loihica PV-4

For carbon source a-Ketoglutaric acid disodium salt hydrate across organisms