Experiment set1H31 for Shewanella loihica PV-4

Compare to:

LB with sodium fluoride 100 mM

200 most detrimental genes:

  gene name fitness t score description  
Shew_2895 +4.2 13.2 2-dehydropantoate 2-reductase (RefSeq) compare
Shew_1058 +3.2 8.4 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_2000 +3.1 3.3 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_1657 sucC +2.3 2.6 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_0296 +2.2 2.0 heat shock protein Hsp20 (RefSeq) compare
Shew_1822 +2.2 9.3 aconitate hydratase (RefSeq) compare
Shew_1224 +2.1 12.5 sodium:dicarboxylate symporter (RefSeq) compare
Shew_2476 +2.0 3.4 MotA/TolQ/ExbB proton channel (RefSeq) compare
Shew_1820 prpB +1.9 2.2 2-methylisocitrate lyase (RefSeq) compare
Shew_1823 +1.9 3.5 putative AcnD-accessory protein PrpF (RefSeq) compare
Shew_2642 +1.8 4.5 flavodoxin (RefSeq) compare
Shew_1809 +1.8 7.9 NAD-glutamate dehydrogenase (RefSeq) compare
Shew_1437 +1.8 11.2 transcriptional regulator, TyrR (RefSeq) compare
Shew_1819 +1.7 4.6 GntR family transcriptional regulator (RefSeq) compare
Shew_3660 +1.7 14.1 glutathione reductase (RefSeq) compare
Shew_2890 +1.6 1.6 peptidyl-prolyl cis-trans isomerase, cyclophilin type (RefSeq) compare
Shew_2572 +1.6 6.3 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_1601 +1.5 2.3 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_0618 +1.5 1.4 hypothetical protein (RefSeq) compare
Shew_3225 +1.4 4.9 glutathione synthetase (RefSeq) compare
Shew_2049 +1.4 3.8 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_2320 +1.4 6.8 RNA methyltransferase (RefSeq) compare
Shew_3432 pdhR +1.4 2.5 transcriptional regulator PdhR (RefSeq) compare
Shew_0421 +1.3 1.8 phage shock protein C, PspC (RefSeq) compare
Shew_2473 +1.3 2.5 tetratricopeptide domain-containing protein (RefSeq) compare
Shew_2459 +1.3 1.1 hypothetical protein (RefSeq) compare
Shew_3682 +1.3 9.7 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_3431 aceE +1.3 9.0 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_2571 +1.3 5.6 propionyl-CoA carboxylase (RefSeq) compare
Shew_3223 +1.3 2.2 deoxyribonuclease I (RefSeq) compare
Shew_1602 +1.2 5.2 malonyl CoA-acyl carrier protein transacylase (RefSeq) compare
Shew_1273 +1.2 1.3 hypothetical protein (RefSeq) compare
Shew_1298 guaA +1.2 7.6 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_1202 +1.2 3.8 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) compare
Shew_3709 +1.2 9.5 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_3681 +1.2 7.9 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_3710 tdh +1.2 6.3 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_2558 +1.2 1.4 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_0755 +1.2 3.8 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_3267 +1.1 4.8 sodium/hydrogen exchanger (RefSeq) compare
Shew_0827 +1.1 1.3 peptidyl-prolyl cis-trans isomerase, cyclophilin type (RefSeq) compare
Shew_1810 +1.1 1.9 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_1646 +1.1 1.1 beta-lactamase domain-containing protein (RefSeq) compare
Shew_3063 +1.1 1.6 glycine cleavage system protein H (RefSeq) compare
Shew_2667 +1.0 7.2 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) compare
Shew_1487 +1.0 2.0 hypothetical protein (RefSeq) compare
Shew_1078 +1.0 6.1 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_0537 +1.0 1.3 hypothetical protein (RefSeq) compare
Shew_1050 +1.0 5.1 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_1563 +1.0 6.9 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_1295 +1.0 2.2 hypothetical protein (RefSeq) compare
Shew_2175 nhaB +1.0 4.1 sodium/proton antiporter (RefSeq) compare
Shew_2656 +1.0 4.1 4'-phosphopantetheinyl transferase (RefSeq) compare
Shew_2918 +1.0 1.0 hypothetical protein (RefSeq) compare
Shew_1925 +1.0 4.9 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (RefSeq) compare
Shew_1865 +1.0 4.2 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_1665 +1.0 1.3 peptidase S51, dipeptidase E (RefSeq) compare
Shew_2252 +1.0 0.7 anthranilate synthase component II (RefSeq) compare
Shew_1092 +0.9 5.0 amino acid carrier protein (RefSeq) compare
Shew_3423 +0.9 1.4 anti-RNA polymerase sigma 70 factor (RefSeq) compare
Shew_1867 +0.9 2.9 hypothetical protein (RefSeq) compare
Shew_2803 +0.9 2.0 DNA-binding transcriptional regulator TorR (RefSeq) compare
Shew_0462 +0.9 1.1 hypothetical protein (RefSeq) compare
Shew_2013 +0.9 1.3 putative DNA-binding transcriptional regulator (RefSeq) compare
Shew_2664 +0.9 4.4 transcriptional regulator, putative (RefSeq) compare
Shew_2910 +0.9 1.0 hypothetical protein (RefSeq) compare
Shew_1163 +0.9 1.6 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_0220 +0.9 2.9 phosphoglycolate phosphatase (RefSeq) compare
Shew_1391 +0.9 1.1 CheW protein (RefSeq) compare
Shew_2565 +0.9 1.8 hypothetical protein (RefSeq) compare
Shew_1927 +0.9 1.2 dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_0086 +0.9 6.6 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_2157 +0.8 1.2 hypothetical protein (RefSeq) compare
Shew_0383 +0.8 2.2 malate dehydrogenase (RefSeq) compare
Shew_2665 +0.8 6.0 beta-ketoacyl synthase (RefSeq) compare
Shew_3500 +0.8 1.7 putative endoribonuclease L-PSP (RefSeq) compare
Shew_2584 +0.8 2.7 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_2637 +0.8 2.2 PII uridylyl-transferase (RefSeq) compare
Shew_1514 upp +0.8 2.1 uracil phosphoribosyltransferase (RefSeq) compare
Shew_2324 +0.8 1.4 type IV pilus assembly PilZ (RefSeq) compare
Shew_2481 +0.8 2.4 porin (RefSeq) compare
Shew_1546 +0.8 1.8 thioesterase superfamily protein (RefSeq) compare
Shew_3271 +0.8 3.5 galactokinase (RefSeq) compare
Shew_2666 +0.8 3.3 omega-3 polyunsaturated fatty acid synthase PfaB (RefSeq) compare
Shew_1244 +0.8 1.0 OsmC family protein (RefSeq) compare
Shew_1010 +0.8 1.7 general secretion pathway protein B (RefSeq) compare
Shew_3311 +0.8 4.4 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_3054 +0.8 1.2 hypothetical protein (RefSeq) compare
Shew_0858 +0.8 1.3 oxidoreductase FAD/NAD(P)-binding subunit (RefSeq) compare
Shew_0620 +0.8 1.3 ion transport 2 domain-containing protein (RefSeq) compare
Shew_1886 +0.8 2.3 alpha amylase, catalytic region (RefSeq) compare
Shew_0091 +0.8 5.2 molybdopterin biosynthesis MoaE (RefSeq) compare
Shew_1574 +0.8 2.4 ATP-binding Mrp/Nbp35 family protein (RefSeq) compare
Shew_1313 +0.8 1.3 TetR family transcriptional regulator (RefSeq) compare
Shew_0197 +0.7 1.1 hypothetical protein (RefSeq) compare
Shew_2460 +0.7 1.8 hypothetical protein (RefSeq) compare
Shew_1920 +0.7 3.3 alpha/beta hydrolase fold (RefSeq) compare
Shew_1970 +0.7 3.2 histidine kinase (RefSeq) compare
Shew_0950 +0.7 2.5 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_3664 +0.7 5.9 alpha-L-glutamate ligase (RefSeq) compare
Shew_0661 +0.7 0.8 hypothetical protein (RefSeq) compare
Shew_2573 +0.7 3.2 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_0799 +0.7 1.4 MarR family transcriptional regulator (RefSeq) compare
Shew_2236 +0.7 1.1 adenine phosphoribosyltransferase (RefSeq) compare
Shew_3351 +0.7 1.4 hypothetical protein (RefSeq) compare
Shew_2740 +0.7 0.5 YfaZ family protein (RefSeq) compare
Shew_1018 +0.7 0.8 hypothetical protein (RefSeq) compare
Shew_0794 +0.7 2.7 diguanylate cyclase (RefSeq) compare
Shew_2223 +0.7 0.8 YceI family protein (RefSeq) compare
Shew_1059 +0.7 1.1 hypothetical protein (RefSeq) compare
Shew_1951 +0.7 2.3 aromatic amino acid aminotransferase (RefSeq) compare
Shew_3064 gcvT +0.7 3.2 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_2090 +0.7 1.0 methyl-accepting chemotaxis protein (RefSeq) compare
Shew_2372 +0.7 0.9 small component of L-lactate and L-malate uptake system (from data) compare
Shew_3295 +0.6 1.9 AFG1 family ATPase (RefSeq) compare
Shew_3442 +0.6 1.3 hypothetical protein (RefSeq) compare
Shew_0586 +0.6 1.4 TPR repeat-containing protein (RefSeq) compare
Shew_2570 +0.6 5.3 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_1881 +0.6 0.8 hypothetical protein (RefSeq) compare
Shew_2204 +0.6 1.0 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) compare
Shew_3537 +0.6 1.1 hypothetical protein (RefSeq) compare
Shew_0054 +0.6 3.9 hypothetical protein (RefSeq) compare
Shew_1341 +0.6 1.3 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_0495 +0.6 0.8 hypothetical protein (RefSeq) compare
Shew_0756 +0.6 1.1 hypothetical protein (RefSeq) compare
Shew_1131 +0.6 1.5 putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) compare
Shew_2128 +0.6 2.0 transglutaminase domain-containing protein (RefSeq) compare
Shew_0484 +0.6 2.0 hypothetical protein (RefSeq) compare
Shew_3549 +0.6 1.3 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_3487 pyrE +0.6 2.2 orotate phosphoribosyltransferase (RefSeq) compare
Shew_3305 +0.6 1.1 CaCA family Na(+)/Ca(+) antiporter (RefSeq) compare
Shew_3495 +0.6 1.0 hypothetical protein (RefSeq) compare
Shew_3598 +0.6 0.5 AsnC family transcriptional regulator (RefSeq) compare
Shew_2544 +0.6 1.3 phosphoglucomutase/phosphomannomutase alpha/beta/subunit (RefSeq) compare
Shew_3131 +0.6 3.3 poly(A) polymerase (RefSeq) compare
Shew_0788 +0.6 1.8 dienelactone hydrolase (RefSeq) compare
Shew_3605 +0.6 0.6 cell division ATP-binding protein FtsE (RefSeq) compare
Shew_3513 +0.6 1.0 hypothetical protein (RefSeq) compare
Shew_3273 +0.6 3.1 hypothetical protein (RefSeq) compare
Shew_0126 +0.6 1.3 hypothetical protein (RefSeq) compare
Shew_1348 flgE +0.6 1.9 flagellar hook protein FlgE (RefSeq) compare
Shew_2668 +0.6 3.7 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_2072 +0.6 0.5 endonuclease III (RefSeq) compare
Shew_1083 +0.6 2.0 apurinic endonuclease Apn1 (RefSeq) compare
Shew_3799 +0.6 0.9 hypothetical protein (RefSeq) compare
Shew_1577 +0.6 0.5 aminotransferase, class IV (RefSeq) compare
Shew_1439 +0.6 3.2 maleylacetoacetate isomerase (RefSeq) compare
Shew_3488 +0.6 0.9 ribonuclease PH (RefSeq) compare
Shew_3377 +0.6 0.4 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_2779 +0.6 0.9 amino acid ABC transporter (RefSeq) compare
Shew_1999 +0.6 0.9 aromatic amino acid aminotransferase (RefSeq) compare
Shew_3655 +0.6 1.4 LysR family transcriptional regulator (RefSeq) compare
Shew_3629 +0.6 1.9 competence protein ComF (RefSeq) compare
Shew_0768 +0.6 1.9 methyltransferase small (RefSeq) compare
Shew_0545 +0.6 2.0 ADP-ribose diphosphatase (RefSeq) compare
Shew_2789 +0.6 2.2 hypothetical protein (RefSeq) compare
Shew_1422 +0.6 0.5 sulfate adenylyltransferase subunit 2 (RefSeq) compare
Shew_3687 +0.5 3.4 molybdopterin-guanine dinucleotide biosynthesis protein B (RefSeq) compare
Shew_1323 +0.5 1.2 acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II-like protein (RefSeq) compare
Shew_2259 +0.5 2.3 metal dependent phosphohydrolase (RefSeq) compare
Shew_3265 +0.5 0.8 CutA1 divalent ion tolerance protein (RefSeq) compare
Shew_1330 +0.5 0.9 Rieske (2Fe-2S) domain-containing protein (RefSeq) compare
Shew_2445 +0.5 1.5 hypothetical protein (RefSeq) compare
Shew_1731 +0.5 0.4 histidine triad (HIT) protein (RefSeq) compare
Shew_2300 +0.5 1.5 hypothetical protein (RefSeq) compare
Shew_1209 +0.5 1.3 pseudouridylate synthase (RefSeq) compare
Shew_1793 +0.5 2.6 vault protein inter-alpha-trypsin subunit (RefSeq) compare
Shew_1146 +0.5 2.1 hypothetical protein (RefSeq) compare
Shew_3430 +0.5 1.0 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_1773 +0.5 0.6 LysR family transcriptional regulator (RefSeq) compare
Shew_2110 +0.5 2.7 hypothetical protein (RefSeq) compare
Shew_0529 +0.5 0.9 Sel1 domain-containing protein (RefSeq) compare
Shew_1425 +0.5 1.1 adenylyl-sulfate kinase (RefSeq) compare
Shew_3201 +0.5 1.5 ABC transporter-related protein (RefSeq) compare
Shew_0053 +0.5 3.4 formate dehydrogenase, subunit FdhD (RefSeq) compare
Shew_1213 +0.5 0.4 RpoD family RNA polymerase sigma factor (RefSeq) compare
Shew_1926 +0.5 1.1 transketolase, central region (RefSeq) compare
Shew_1812 +0.5 2.1 23S rRNA m(2)G2445 methyltransferase (RefSeq) compare
Shew_0938 +0.5 1.1 TonB-dependent receptor (RefSeq) compare
Shew_0046 +0.5 3.1 molybdenum cofactor synthesis domain-containing protein (RefSeq) compare
Shew_1714 +0.5 1.0 alpha/beta hydrolase fold (RefSeq) compare
Shew_0047 +0.5 2.4 molybdopterin biosynthesis protein MoeB (RefSeq) compare
Shew_2561 +0.5 2.3 6-phosphogluconate dehydrogenase (RefSeq) compare
Shew_2167 +0.5 1.1 hypothetical protein (RefSeq) compare
Shew_2451 +0.5 2.1 patatin (RefSeq) compare
Shew_2096 +0.5 1.1 thiamine biosynthesis protein ThiC (RefSeq) compare
Shew_1893 +0.5 2.2 hypothetical protein (RefSeq) compare
Shew_2947 +0.5 2.1 hypothetical protein (RefSeq) compare
Shew_1590 +0.5 0.4 2OG-Fe(II) oxygenase (RefSeq) compare
Shew_2418 +0.5 1.1 hypothetical protein (RefSeq) compare
Shew_0438 +0.5 0.4 GumN family protein (RefSeq) compare
Shew_1550 +0.5 3.0 FAD linked oxidase domain-containing protein (RefSeq) compare
Shew_0448 +0.5 1.7 periplasmic solute binding protein (RefSeq) compare
Shew_2282 +0.5 0.7 Fis family transcriptional regulator (RefSeq) compare
Shew_2429 +0.5 0.4 hypothetical protein (RefSeq) compare
Shew_3718 +0.5 0.5 hypothetical protein (RefSeq) compare
Shew_2198 +0.5 0.9 histidinol dehydrogenase (RefSeq) compare
Shew_0782 +0.5 1.3 DNA-binding transcriptional regulator AsnC (RefSeq) compare
Shew_3622 hslO +0.5 1.3 Hsp33-like chaperonin (RefSeq) compare
Shew_1713 +0.5 1.1 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare


Specific Phenotypes

None in this experiment

For Shewanella loihica PV-4 in stress experiments

For stress sodium fluoride across organisms