Experiment set1H29 for Shewanella sp. ANA-3

Compare to:

L-Alanine carbon source

200 most detrimental genes:

  gene name fitness t score description  
Shewana3_0576 +5.5 20.7 multi-sensor hybrid histidine kinase (RefSeq) compare
Shewana3_0650 +5.3 19.5 two-component response regulator (RefSeq) compare
Shewana3_1655 +4.1 15.1 glycine cleavage system transcriptional repressor, putative (RefSeq) compare
Shewana3_0599 +3.9 8.4 HflK protein (RefSeq) compare
Shewana3_1785 +3.1 18.0 glutamate dehydrogenase (NAD) (RefSeq) compare
Shewana3_3812 +3.1 10.0 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shewana3_0716 +3.0 15.4 TonB-dependent siderophore receptor (RefSeq) compare
Shewana3_2782 +3.0 7.9 UDP-glucose pyrophosphorylase (RefSeq) compare
Shewana3_0717 +3.0 9.6 putative hydroxylase (RefSeq) compare
Shewana3_4041 +2.9 15.2 LemA family protein (RefSeq) compare
Shewana3_2295 +2.8 11.4 L-serine ammonia-lyase (RefSeq) compare
Shewana3_1375 +2.7 4.1 polysaccharide export protein (RefSeq) compare
Shewana3_1604 +2.7 10.1 hypothetical protein (RefSeq) compare
Shewana3_1376 +2.4 5.1 lipopolysaccharide biosynthesis (RefSeq) compare
Shewana3_1582 +2.4 2.4 GntR family transcriptional regulator (RefSeq) compare
Shewana3_1426 +2.4 10.4 serine/threonine transporter SstT (RefSeq) compare
Shewana3_0156 +2.3 4.1 general secretion pathway protein I (RefSeq) compare
Shewana3_2783 +2.3 9.1 UDP-galactose 4-epimerase (RefSeq) compare
Shewana3_0197 +2.2 4.6 elongation factor Tu (RefSeq) compare
Shewana3_0417 +2.2 6.6 type 4 prepilin peptidase 1. Aspartic peptidase. MEROPS family A24A (RefSeq) compare
Shewana3_2654 +2.2 4.6 ABC transporter related (RefSeq) compare
Shewana3_1349 fliM +2.1 4.5 flagellar motor switch protein FliM (RefSeq) compare
Shewana3_0681 +2.1 9.5 toluene tolerance family protein (RefSeq) compare
Shewana3_0996 +2.1 2.1 rRNA large subunit methyltransferase (RefSeq) compare
Shewana3_0399 +2.1 5.9 nifR3 family TIM-barrel protein (RefSeq) compare
Shewana3_1342 fliF +2.0 11.2 flagellar MS-ring protein (RefSeq) compare
Shewana3_1350 fliN +2.0 7.6 flagellar motor switch protein (RefSeq) compare
Shewana3_0160 +2.0 11.5 general secretion pathway M protein (RefSeq) compare
Shewana3_3439 +2.0 5.3 LysR family transcriptional regulator (RefSeq) compare
Shewana3_0157 +1.9 9.7 general secretion pathway protein J (RefSeq) compare
Shewana3_0696 +1.9 4.2 Sel1 domain-containing protein (RefSeq) compare
Shewana3_1354 fliR +1.9 10.5 flagellar biosynthesis protein FliR (RefSeq) compare
Shewana3_1351 +1.9 5.0 flagellar biosynthesis protein, FliO (RefSeq) compare
Shewana3_3487 +1.9 1.5 hypothetical protein (RefSeq) compare
Shewana3_3882 +1.9 5.7 phosphoheptose isomerase (RefSeq) compare
Shewana3_0154 +1.9 2.7 general secretion pathway protein G (RefSeq) compare
Shewana3_1345 fliI +1.9 10.5 flagellum-specific ATP synthase (RefSeq) compare
Shewana3_4174 +1.8 3.2 hypothetical protein (RefSeq) compare
Shewana3_1328 flgI +1.8 8.1 flagellar basal body P-ring protein (RefSeq) compare
Shewana3_2898 +1.8 8.2 flagellar motor protein PomA (RefSeq) compare
Shewana3_1368 +1.8 3.9 hypothetical protein (RefSeq) compare
Shewana3_1329 flgJ +1.8 5.4 flagellar rod assembly protein/muramidase FlgJ (RefSeq) compare
Shewana3_1316 +1.8 4.2 FlgN family protein (RefSeq) compare
Shewana3_1890 +1.8 1.6 hypothetical protein (RefSeq) compare
Shewana3_0159 +1.8 10.0 general secretion pathway protein L (RefSeq) compare
Shewana3_1344 fliH +1.8 8.7 flagellar assembly protein H (RefSeq) compare
Shewana3_1371 +1.7 7.3 VacJ family lipoprotein (RefSeq) compare
Shewana3_1324 flgE +1.7 11.0 flagellar hook protein FlgE (RefSeq) compare
Shewana3_3424 +1.7 1.3 methylation site containing protein (RefSeq) compare
Shewana3_1326 flgG +1.7 9.4 flagellar basal body rod protein FlgG (RefSeq) compare
Shewana3_1657 +1.7 5.3 NlpB/DapX family lipoprotein (RefSeq) compare
Shewana3_1356 flhA +1.7 9.7 flagellar biosynthesis protein FlhA (RefSeq) compare
Shewana3_0679 +1.7 4.9 hypothetical protein (RefSeq) compare
Shewana3_1338 +1.6 6.1 sigma-54 dependent trancsriptional regulator (RefSeq) compare
Shewana3_0600 +1.6 2.8 HflC protein (RefSeq) compare
Shewana3_1343 fliG +1.6 6.4 flagellar motor switch protein G (RefSeq) compare
Shewana3_1231 +1.6 2.8 hypothetical protein (RefSeq) compare
Shewana3_0151 +1.6 10.9 general secretion pathway protein D (RefSeq) compare
Shewana3_0153 +1.6 6.9 general secretion pathway protein F (RefSeq) compare
Shewana3_1325 flgF +1.6 7.8 flagellar basal body rod protein FlgF (RefSeq) compare
Shewana3_3182 +1.6 5.9 MltA-interacting MipA family protein (RefSeq) compare
Shewana3_2897 motB +1.6 7.9 flagellar motor protein MotB (RefSeq) compare
Shewana3_0682 +1.6 3.6 SpoIIAA family protein (RefSeq) compare
Shewana3_0150 +1.6 5.7 general secretion pathway protein C (RefSeq) compare
Shewana3_1318 flgA +1.6 6.0 flagellar basal body P-ring biosynthesis protein FlgA (RefSeq) compare
Shewana3_1738 +1.6 1.6 hypothetical protein (RefSeq) compare
Shewana3_0680 +1.6 6.0 hypothetical protein (RefSeq) compare
Shewana3_0027 +1.6 7.5 TrkH family potassium uptake protein (RefSeq) compare
Shewana3_1341 +1.6 5.7 flagellar hook-basal body complex subunit FliE (RefSeq) compare
Shewana3_3569 +1.5 5.7 MATE efflux family protein (RefSeq) compare
Shewana3_1378 +1.5 11.8 glycosyl transferase family protein (RefSeq) compare
Shewana3_0152 +1.5 7.3 type II secretion system protein E (GspE) (RefSeq) compare
Shewana3_3037 +1.5 1.7 hypothetical protein (RefSeq) compare
Shewana3_1355 flhB +1.5 5.6 flagellar biosynthesis protein FlhB (RefSeq) compare
Shewana3_1335 +1.5 3.2 flagellar hook-associated 2 domain-containing protein (RefSeq) compare
Shewana3_1583 +1.5 4.4 D,D-heptose 1,7-bisphosphate phosphatase (RefSeq) compare
Shewana3_3006 +1.4 8.4 leucyl aminopeptidase (RefSeq) compare
Shewana3_1333 +1.4 4.2 flagellin domain-containing protein (RefSeq) compare
Shewana3_1498 +1.4 2.3 hypothetical protein (RefSeq) compare
Shewana3_1348 fliL +1.4 6.6 flagellar basal body-associated protein FliL (RefSeq) compare
Shewana3_1670 +1.4 3.5 methylglutaconyl-CoA hydratase (RefSeq) compare
Shewana3_3041 +1.4 4.9 hypothetical protein (RefSeq) compare
Shewana3_1322 flgC +1.4 7.0 flagellar basal body rod protein FlgC (RefSeq) compare
Shewana3_1323 flgD +1.4 8.0 flagellar basal body rod modification protein (RefSeq) compare
Shewana3_1724 +1.4 3.9 two component transcriptional regulator (RefSeq) compare
Shewana3_2519 +1.4 2.3 biotin synthase (RefSeq) compare
Shewana3_0991 +1.4 1.3 penicillin-binding protein 6 (RefSeq) compare
Shewana3_1330 +1.3 6.5 flagellar hook-associated protein FlgK (RefSeq) compare
Shewana3_0126 +1.3 6.5 flagellar basal body-associated protein FliL-like protein (RefSeq) compare
Shewana3_3073 +1.3 5.3 citrate transporter (RefSeq) compare
Shewana3_1307 +1.3 9.1 hypothetical protein (RefSeq) compare
Shewana3_1347 +1.3 5.3 flagellar hook-length control protein (RefSeq) compare
Shewana3_1377 +1.2 9.1 sugar transferase (RefSeq) compare
Shewana3_1751 +1.2 5.4 cold-shock DNA-binding protein family protein (RefSeq) compare
Shewana3_4105 tdh +1.2 3.9 L-threonine 3-dehydrogenase (RefSeq) compare
Shewana3_1339 +1.2 5.2 PAS/PAC sensor signal transduction histidine kinase (RefSeq) compare
Shewana3_3030 +1.2 1.8 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shewana3_1946 +1.2 4.2 response regulator receiver protein (RefSeq) compare
Shewana3_3811 rpoZ +1.2 3.0 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shewana3_0779 +1.2 5.1 nitrogen regulatory protein P-II (RefSeq) compare
Shewana3_0678 +1.2 3.7 ABC transporter related (RefSeq) compare
Shewana3_0155 +1.2 2.9 general secretion pathway protein H (RefSeq) compare
Shewana3_0445 +1.2 1.5 hypothetical protein (RefSeq) compare
Shewana3_0411 +1.2 8.9 Ppx/GppA phosphatase (RefSeq) compare
Shewana3_2949 +1.2 2.2 SmpA/OmlA domain-containing protein (RefSeq) compare
Shewana3_0158 +1.2 4.7 general secretion pathway protein K (RefSeq) compare
Shewana3_2027 +1.1 2.0 N-6 DNA methylase (RefSeq) compare
Shewana3_3575 +1.1 2.4 CutA1 divalent ion tolerance protein (RefSeq) compare
Shewana3_4373 +1.1 1.7 hypothetical protein (RefSeq) compare
Shewana3_1359 fliA +1.1 2.2 flagellar biosynthesis sigma factor (RefSeq) compare
Shewana3_1331 flgL +1.1 3.8 flagellar hook-associated protein FlgL (RefSeq) compare
Shewana3_1963 ansA +1.1 3.2 cytoplasmic asparaginase I (RefSeq) compare
Shewana3_0148 hslO +1.1 5.0 Hsp33-like chaperonin (RefSeq) compare
Shewana3_0849 +1.1 7.1 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) compare
Shewana3_2288 +1.1 3.1 hypothetical protein (RefSeq) compare
Shewana3_2117 +1.1 1.7 PP-loop domain-containing protein (RefSeq) compare
Shewana3_4083 +1.1 6.0 hypothetical protein (RefSeq) compare
Shewana3_0377 +1.1 2.8 hypothetical protein (RefSeq) compare
Shewana3_2539 +1.1 5.2 OmpA/MotB domain-containing protein (RefSeq) compare
Shewana3_3737 +1.1 1.2 hypothetical protein (RefSeq) compare
Shewana3_3531 +1.0 6.2 Rh family protein/ammonium transporter (RefSeq) compare
Shewana3_3821 +1.0 2.1 putative acyltransferase (RefSeq) compare
Shewana3_2131 +1.0 3.4 dehydrogenase, E1 component (RefSeq) compare
Shewana3_0050 +1.0 2.0 peptidase M23B (RefSeq) compare
Shewana3_3711 +1.0 1.4 hypothetical protein (RefSeq) compare
Shewana3_4100 +1.0 4.1 glycosyl transferase family protein (RefSeq) compare
Shewana3_2544 upp +1.0 3.2 uracil phosphoribosyltransferase (RefSeq) compare
Shewana3_0778 +1.0 6.5 ammonium transporter (RefSeq) compare
Shewana3_1313 +1.0 4.5 hypothetical protein (RefSeq) compare
Shewana3_1466 +1.0 3.8 phosphohistidine phosphatase, SixA (RefSeq) compare
Shewana3_1606 +1.0 3.5 3-hydroxydecanoyl-(acyl carrier protein) dehydratase (RefSeq) compare
Shewana3_2138 +1.0 2.9 LexA regulated protein (RefSeq) compare
Shewana3_4119 +1.0 1.1 alpha/beta hydrolase fold (RefSeq) compare
Shewana3_2009 +1.0 1.3 hypothetical protein (RefSeq) compare
Shewana3_1337 fliS +1.0 3.5 flagellar protein FliS (RefSeq) compare
Shewana3_2943 +0.9 2.0 malate synthase (RefSeq) compare
Shewana3_2821 purU +0.9 5.6 formyltetrahydrofolate deformylase (RefSeq) compare
Shewana3_1689 +0.9 1.8 hypothetical protein (RefSeq) compare
Shewana3_1327 flgH +0.9 1.8 flagellar basal body L-ring protein (RefSeq) compare
Shewana3_3764 +0.9 1.7 hypothetical protein (RefSeq) compare
Shewana3_2746 +0.9 1.3 hypothetical protein (RefSeq) compare
Shewana3_1357 flhF +0.9 4.4 flagellar biosynthesis regulator FlhF (RefSeq) compare
Shewana3_2121 +0.9 2.2 aromatic amino acid aminotransferase (RefSeq) compare
Shewana3_0267 +0.9 7.1 hypothetical protein (RefSeq) compare
Shewana3_0181 +0.9 1.8 RNP-1-like RNA-binding protein (RefSeq) compare
Shewana3_1664 +0.9 1.7 ThiJ/PfpI domain-containing protein (RefSeq) compare
Shewana3_3332 +0.9 4.7 branched-chain amino acid transport system II carrier protein (RefSeq) compare
Shewana3_3022 acpS +0.9 1.8 4'-phosphopantetheinyl transferase (RefSeq) compare
Shewana3_3433 +0.9 1.7 periplasmic nitrate reductase subunit NapB (RefSeq) compare
Shewana3_3340 +0.9 5.9 putative PAS/PAC sensor protein (RefSeq) compare
Shewana3_0798 +0.9 5.3 DNA-binding transcriptional regulator AsnC (RefSeq) compare
Shewana3_0690 +0.9 1.2 peptidase Do (RefSeq) compare
Shewana3_0285 +0.9 1.1 hypothetical protein (RefSeq) compare
Shewana3_1954 +0.9 1.6 hypothetical protein (RefSeq) compare
Shewana3_1778 +0.9 3.8 carboxy-terminal protease (RefSeq) compare
Shewana3_0670 +0.9 1.8 PTS IIA-like nitrogen-regulatory protein PtsN (RefSeq) compare
Shewana3_0410 +0.9 4.5 ATP-dependent RNA helicase RhlB (RefSeq) compare
Shewana3_0710 +0.9 1.9 iron hydrogenase, small subunit (RefSeq) compare
Shewana3_0605 +0.9 2.1 ClpXP protease specificity-enhancing factor (RefSeq) compare
Shewana3_3394 +0.9 1.1 hypothetical protein (RefSeq) compare
Shewana3_1018 +0.9 1.5 hypothetical protein (RefSeq) compare
Shewana3_2724 +0.9 0.9 GCN5-related N-acetyltransferase (RefSeq) compare
Shewana3_2816 +0.9 5.2 methionine aminopeptidase (RefSeq) compare
Shewana3_1303 +0.9 4.0 polysaccharide biosynthesis protein (RefSeq) compare
Shewana3_1364 +0.9 3.3 hypothetical protein (RefSeq) compare
Shewana3_1701 +0.9 1.3 hypothetical protein (RefSeq) compare
Shewana3_2941 +0.9 3.9 thioesterase superfamily protein (RefSeq) compare
Shewana3_1126 recA +0.8 1.9 recombinase A (RefSeq) compare
Shewana3_1868 +0.8 1.7 hydrogenase expression/formation protein HypE (RefSeq) compare
Shewana3_1744 +0.8 1.8 cupin 4 family protein (RefSeq) compare
Shewana3_1016 +0.8 1.3 hypothetical protein (RefSeq) compare
Shewana3_1029 nusA +0.8 0.7 transcription elongation factor NusA (RefSeq) compare
Shewana3_3570 +0.8 1.1 LysR family transcriptional regulator (RefSeq) compare
Shewana3_4355 +0.8 2.0 hypothetical protein (RefSeq) compare
Shewana3_2335 +0.8 1.0 ArsR family transcriptional regulator (RefSeq) compare
Shewana3_2509 +0.8 1.6 LuxR family transcriptional regulator (RefSeq) compare
Shewana3_1608 +0.8 1.8 response regulator (RefSeq) compare
Shewana3_2364 +0.8 4.9 hypothetical protein (RefSeq) compare
Shewana3_3699 +0.8 2.2 ATP-dependent protease peptidase subunit (RefSeq) compare
Shewana3_1308 +0.8 3.2 GCN5-related N-acetyltransferase (RefSeq) compare
Shewana3_1174 +0.8 1.5 hypothetical protein (RefSeq) compare
Shewana3_0838 +0.8 1.4 MerR family transcriptional regulator (RefSeq) compare
Shewana3_1774 +0.8 1.8 paraquat-inducible protein A (RefSeq) compare
Shewana3_0086 +0.8 1.5 MerR family transcriptional regulator (RefSeq) compare
Shewana3_0477 +0.8 1.6 hypothetical protein (RefSeq) compare
Shewana3_0505 fre +0.8 1.6 FMN reductase (RefSeq) compare
Shewana3_3361 +0.8 1.7 protein of unknown function DUF306, Meta and HslJ (RefSeq) compare
Shewana3_0035 def +0.7 3.4 peptide deformylase (RefSeq) compare
Shewana3_2891 +0.7 1.5 putative RNA 2'-O-ribose methyltransferase (RefSeq) compare
Shewana3_1816 +0.7 1.4 hypothetical protein (RefSeq) compare
Shewana3_1723 +0.7 2.5 ATPase domain-containing protein (RefSeq) compare
Shewana3_0750 +0.7 3.0 malate dehydrogenase (RefSeq) compare
Shewana3_0161 +0.7 2.6 type II secretion system protein N (RefSeq) compare
Shewana3_0921 +0.7 1.4 ApbE family protein, putative (RefSeq) compare
Shewana3_3159 +0.7 2.5 hypothetical protein (RefSeq) compare
Shewana3_1374 +0.7 2.5 transcription antitermination protein nusG (RefSeq) compare
Shewana3_3618 +0.7 0.6 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shewana3_2324 +0.7 2.4 sodium/hydrogen exchanger (RefSeq) compare
Shewana3_1367 +0.7 1.3 CheW protein (RefSeq) compare
Shewana3_0452 +0.7 1.3 thioredoxin (RefSeq) compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source L-Alanine in Shewanella sp. ANA-3

For carbon source L-Alanine across organisms