Experiment set1H25 for Pseudomonas stutzeri RCH2

Compare to:

L-Proline carbon source

200 most important genes:

  gene name fitness t score description  
Psest_3648 -8.0 -5.6 anthranilate phosphoribosyltransferase compare
Psest_2584 -7.2 -9.9 Phosphoribosylanthranilate isomerase compare
Psest_3650 -6.7 -18.5 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_3810 -6.2 -4.3 orotate phosphoribosyltransferase compare
Psest_3647 -6.2 -10.3 Indole-3-glycerol phosphate synthase compare
Psest_3299 -6.0 -18.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_1947 -6.0 -4.2 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_0279 -6.0 -10.0 methionine biosynthesis protein MetW compare
Psest_2590 -6.0 -2.7 3-isopropylmalate dehydratase, small subunit compare
Psest_3866 -5.8 -23.7 threonine ammonia-lyase, biosynthetic, long form compare
Psest_2589 -5.8 -15.1 3-isopropylmalate dehydrogenase compare
Psest_3298 -5.8 -13.3 histidinol dehydrogenase compare
Psest_2591 -5.7 -4.7 3-isopropylmalate dehydratase, large subunit compare
Psest_0155 -5.6 -10.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_0152 -5.6 -6.8 Imidazoleglycerol-phosphate dehydratase compare
Psest_1474 -5.5 -3.8 phosphoribosylaminoimidazole synthetase compare
Psest_2578 -5.5 -17.4 O-succinylhomoserine sulfhydrylase compare
Psest_0280 -5.4 -16.7 homoserine O-acetyltransferase compare
Psest_2579 -5.1 -9.7 amidophosphoribosyltransferase compare
Psest_0153 -4.9 -19.7 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_0687 -4.8 -11.6 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_0325 -4.7 -18.2 Putative threonine efflux protein compare
Psest_3864 -4.6 -20.2 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0062 -4.6 -13.5 tryptophan synthase, alpha subunit compare
Psest_3944 -4.6 -3.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_1814 -4.6 -26.6 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_1473 -4.5 -16.6 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_1772 -4.3 -10.7 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0063 -4.1 -11.7 tryptophan synthase, beta subunit compare
Psest_3123 -4.1 -6.2 dihydroorotase, homodimeric type compare
Psest_0313 -4.1 -8.6 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_1013 -4.0 -7.6 phosphoribosylamine--glycine ligase compare
Psest_3226 -3.9 -2.1 Predicted membrane protein compare
Psest_1037 -3.8 -5.7 acetolactate synthase, small subunit compare
Psest_1452 -3.8 -15.2 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_1704 -3.8 -4.8 Dehydrogenases (flavoproteins) compare
Psest_1295 -3.8 -13.3 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0489 -3.8 -6.2 phosphoserine phosphatase SerB compare
Psest_3159 -3.7 -9.8 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0412 -3.6 -17.5 8-amino-7-oxononanoate synthase compare
Psest_3943 -3.4 -5.2 Phosphoribosyl-AMP cyclohydrolase compare
Psest_0306 -3.4 -22.6 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_0414 -3.4 -10.1 biotin biosynthesis protein BioC compare
Psest_0285 -3.0 -12.9 pilus retraction protein PilT compare
Psest_0411 -3.0 -13.5 biotin synthetase compare
Psest_0413 -2.8 -8.7 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_0415 -2.8 -7.6 dethiobiotin synthase compare
Psest_1496 -2.7 -4.1 Holliday junction DNA helicase, RuvA subunit compare
Psest_2967 -2.7 -6.4 flagellar basal-body rod protein FlgC compare
Psest_0417 -2.6 -7.4 Acyl-CoA dehydrogenases compare
Psest_3649 -2.5 -12.4 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0999 -2.4 -4.4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3721 -2.4 -11.4 Malic enzyme compare
Psest_2968 -2.4 -11.0 flagellar basal-body rod protein FlgB compare
Psest_3720 -2.4 -18.0 penicillin-binding protein, 1A family compare
Psest_2232 -2.4 -15.3 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_3129 -2.3 -3.3 tyrosine recombinase XerD compare
Psest_0466 -2.3 -7.3 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_1765 -2.3 -8.7 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0771 -2.3 -14.0 Acyl-CoA hydrolase compare
Psest_3862 -2.2 -15.7 phosphoenolpyruvate-protein phosphotransferase compare
Psest_4191 -2.2 -3.9 Transcriptional regulator compare
Psest_1144 -2.1 -7.2 AmpG-related permease compare
Psest_0326 -2.0 -6.4 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_1486 -2.0 -4.5 hypothetical protein compare
Psest_2088 -2.0 -3.2 Uncharacterized protein conserved in bacteria compare
Psest_1686 -2.0 -6.2 fatty acid/phospholipid synthesis protein PlsX compare
Psest_2719 -2.0 -6.3 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_3637 -2.0 -7.2 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases compare
Psest_2312 -1.9 -9.1 Small-conductance mechanosensitive channel compare
Psest_0969 -1.9 -4.0 transcription elongation factor GreA compare
Psest_3768 -1.9 -5.7 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED/haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E compare
Psest_2944 -1.8 -5.9 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_0442 -1.8 -9.9 ATPases of the AAA+ class compare
Psest_3998 -1.8 -7.8 glutamate--cysteine ligase compare
Psest_4075 -1.8 -11.3 symporter for L-glutamate, L-glutamine, and L-proline (from data) compare
Psest_3700 -1.8 -0.7 hypothetical protein compare
Psest_2585 -1.8 -2.3 pseudouridylate synthase I compare
Psest_2001 -1.8 -3.7 2-phosphoglycolate phosphatase, prokaryotic compare
Psest_3079 -1.8 -9.7 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) conserved
Psest_0136 -1.8 -12.4 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_1994 -1.7 -6.4 Amidases related to nicotinamidase compare
Psest_3317 -1.7 -5.7 Phosphotransferase System HPr (HPr) Family compare
Psest_2963 -1.7 -10.0 flagellar basal-body rod protein FlgG, Gram-negative bacteria compare
Psest_2965 -1.7 -14.5 fagellar hook-basal body proteins compare
Psest_0139 -1.7 -8.3 ABC-type histidine transport system, ATPase component compare
Psest_0993 -1.7 -9.6 Glucose-6-phosphate isomerase compare
Psest_2971 -1.7 -8.3 flagella basal body P-ring formation protein FlgA compare
Psest_0137 -1.7 -10.0 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_1516 -1.6 -2.5 Uncharacterized lipoprotein compare
Psest_2964 -1.6 -7.1 flagellar basal-body rod protein FlgF compare
Psest_1721 -1.6 -4.1 Flagellar biosynthesis/type III secretory pathway protein compare
Psest_2961 -1.6 -5.7 Flagellar basal-body P-ring protein compare
Psest_0292 -1.6 -3.4 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_4077 -1.6 -10.5 amino acid carrier protein compare
Psest_0138 -1.6 -11.1 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_3732 -1.6 -9.7 polyphosphate kinase 1 compare
Psest_1260 -1.6 -8.0 type IV pilus biogenesis/stability protein PilW compare
Psest_2090 -1.6 -5.0 Protein of unknown function (DUF2970). compare
Psest_1054 -1.6 -5.1 Diaminopimelate decarboxylase compare
Psest_3084 -1.6 -2.9 methyltransferase, putative compare
Psest_2946 -1.6 -5.9 septum site-determining protein MinD compare
Psest_3307 -1.6 -8.5 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_3289 -1.6 -9.6 prepilin-type N-terminal cleavage/methylation domain compare
Psest_1489 -1.5 -5.9 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases compare
Psest_3697 -1.5 -2.0 Outer membrane lipoprotein carrier protein LolA. compare
Psest_2958 -1.5 -12.4 flagellar hook-associated protein 3 compare
Psest_0198 -1.5 -8.4 TRAP transporter solute receptor, TAXI family compare
Psest_2962 -1.5 -9.4 Flagellar basal body L-ring protein compare
Psest_3719 -1.5 -10.7 type IV pilus assembly protein PilM compare
Psest_1292 -1.5 -9.5 monothiol glutaredoxin, Grx4 family compare
Psest_2960 -1.5 -10.4 flagellar rod assembly protein/muramidase FlgJ compare
Psest_0393 -1.5 -6.7 Methylase of chemotaxis methyl-accepting proteins compare
Psest_3717 -1.5 -6.6 Tfp pilus assembly protein PilO compare
Psest_1723 -1.4 -7.5 flagellar export protein FliJ compare
Psest_1729 -1.4 -6.7 flagellar motor switch protein FliM compare
Psest_0715 -1.4 -10.9 NADH dehydrogenase, FAD-containing subunit conserved
Psest_0197 -1.4 -10.6 TRAP transporter, 4TM/12TM fusion protein compare
Psest_1718 -1.4 -5.9 flagellar hook-basal body complex protein FliE compare
Psest_3304 -1.4 -7.3 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_2959 -1.4 -11.8 flagellar hook-associated protein FlgK compare
Psest_1737 -1.4 -7.7 flagellar biosynthesis protein FlhA compare
Psest_2973 -1.4 -8.8 Flagellar biosynthesis/type III secretory pathway chaperone compare
Psest_1735 -1.4 -7.9 flagellar biosynthetic protein FlhB compare
Psest_2863 -1.3 -6.8 Transcriptional regulator compare
Psest_1734 -1.3 -8.5 flagellar biosynthetic protein FliR compare
Psest_1719 -1.3 -6.5 flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF) compare
Psest_3305 -1.3 -7.8 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_1724 -1.3 -4.8 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_0514 -1.3 -7.3 lytic murein transglycosylase B compare
Psest_0445 -1.3 -10.5 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_0066 -1.3 -1.6 Protein of unknown function (DUF3060). compare
Psest_1722 -1.3 -8.4 flagellar protein export ATPase FliI compare
Psest_2379 -1.3 -9.5 PAS domain S-box compare
Psest_3716 -1.3 -8.9 Tfp pilus assembly protein PilP compare
Psest_1031 -1.3 -6.8 Uncharacterized protein conserved in bacteria compare
Psest_3872 -1.3 -8.4 FAD/FMN-containing dehydrogenases compare
Psest_1740 -1.3 -7.0 RNA polymerase sigma factor, FliA/WhiG family compare
Psest_1738 -1.3 -5.5 flagellar biosynthetic protein FlhF compare
Psest_1957 -1.3 -9.6 outer membrane porin, OprD family. compare
Psest_0496 -1.3 -7.6 flagellar motor stator protein MotA compare
Psest_1463 -1.3 -2.0 SufE protein probably involved in Fe-S center assembly compare
Psest_2966 -1.3 -6.7 Flagellar hook capping protein compare
Psest_3447 -1.3 -0.9 Uncharacterized MobA-related protein compare
Psest_3664 -1.3 -2.5 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_2712 -1.2 -6.8 Surface lipoprotein compare
Psest_1720 -1.2 -8.6 flagellar motor switch protein FliG compare
Psest_3306 -1.2 -3.7 conserved hypothetical integral membrane protein compare
Psest_4221 -1.2 -4.3 homoserine kinase, Neisseria type compare
Psest_1813 -1.2 -4.6 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_4280 -1.2 -4.4 ABC-type spermidine/putrescine transport system, permease component II compare
Psest_4273 -1.2 -7.8 Lysophospholipase compare
Psest_2643 -1.2 -3.9 Beta-glucosidase-related glycosidases compare
Psest_0259 -1.2 -1.7 cell division ATP-binding protein FtsE compare
Psest_4310 -1.2 -2.2 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_2322 -1.2 -3.0 Transcriptional regulators compare
Psest_1732 -1.2 -5.0 flagellar biosynthetic protein FliP compare
Psest_2507 -1.2 -9.6 Flagellin and related hook-associated proteins compare
Psest_3715 -1.1 -9.7 type IV pilus secretin (or competence protein) PilQ compare
Psest_3373 -1.1 -4.4 Tfp pilus assembly protein PilX compare
Psest_2083 -1.1 -7.1 Putative sterol carrier protein compare
Psest_3896 -1.1 -1.3 arsenite-activated ATPase ArsA compare
Psest_3303 -1.1 -4.9 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_1819 -1.1 -9.8 Nucleoside-diphosphate-sugar epimerases compare
Psest_1733 -1.1 -2.7 flagellar biosynthetic protein FliQ compare
Psest_0497 -1.1 -5.0 Flagellar motor protein compare
Psest_1812 -1.1 -8.1 pseudaminic acid CMP-transferase compare
Psest_0515 -1.1 -3.5 rare lipoprotein A compare
Psest_3718 -1.0 -5.3 Tfp pilus assembly protein PilN compare
Psest_3288 -1.0 -8.4 type IV-A pilus assembly ATPase PilB compare
Psest_2357 -1.0 -2.0 Short-chain dehydrogenases of various substrate specificities compare
Psest_4303 -1.0 -0.7 HEAT repeat. compare
Psest_3406 -1.0 -8.4 Restriction endonuclease S subunits compare
Psest_4363 -1.0 -6.9 ATPases involved in chromosome partitioning compare
Psest_2862 -1.0 -7.0 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Psest_0551 -1.0 -4.8 PEP phosphonomutase and related enzymes compare
Psest_2775 -1.0 -4.2 Glycerol-3-phosphate dehydrogenase compare
Psest_1731 -1.0 -2.8 flagellar biosynthetic protein FliO compare
Psest_1540 -1.0 -2.0 biotin-dependent carboxylase uncharacterized domain compare
Psest_3287 -1.0 -5.1 Type II secretory pathway, component PulF compare
Psest_1728 -1.0 -5.0 Flagellar basal body-associated protein compare
Psest_3286 -1.0 -5.3 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases compare
Psest_1824 -1.0 -3.1 Sugar transferases involved in lipopolysaccharide synthesis compare
Psest_0857 -1.0 -1.1 Membrane transporters of cations and cationic drugs compare
Psest_2955 -1.0 -3.8 Predicted transcriptional regulator with C-terminal CBS domains compare
Psest_2015 -1.0 -3.2 Type II secretory pathway, component PulD compare
Psest_3502 -0.9 -2.5 flavoprotein, HI0933 family/uncharacterized flavoprotein, PP_4765 family compare
Psest_2333 -0.9 -1.4 Protein of unknown function (DUF3359). compare
Psest_3803 -0.9 -1.7 DNA repair protein radc compare
Psest_3813 -0.9 -5.5 ribonuclease PH compare
Psest_2645 -0.9 -4.7 Transcriptional regulator compare
Psest_2945 -0.9 -2.3 septum site-determining protein MinC compare
Psest_1746 -0.9 -4.5 Flagellar motor protein compare
Psest_2324 -0.9 -7.8 hypothetical protein compare
Psest_3433 -0.9 -6.2 ATP-binding cassette protein, ChvD family compare
Psest_2806 -0.9 -5.0 RNA polymerase sigma factor RpoS compare
Psest_3762 -0.9 -4.3 iron donor protein CyaY compare
Psest_0709 -0.9 -6.1 pseudouridine synthase, RluA family compare
Psest_3458 -0.9 -1.6 hypothetical protein compare
Psest_2380 -0.9 -7.3 Uncharacterized conserved protein compare


Specific Phenotypes

For 14 genes in this experiment

For carbon source L-Proline in Pseudomonas stutzeri RCH2

For carbon source L-Proline across organisms