Experiment set1H2 for Shewanella loihica PV-4

Compare to:

LB with MreB Perturbing Compound A22 0.005 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Shew_1058 +3.0 17.1 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_1298 guaA +2.9 20.5 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_2049 +2.9 18.8 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_0296 +2.8 5.2 heat shock protein Hsp20 (RefSeq) compare
Shew_0728 +2.7 19.6 dihydroorotase (RefSeq) compare
Shew_2000 +2.4 4.9 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_3430 +2.3 3.9 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_1657 sucC +2.1 2.2 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_1601 +2.1 4.8 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_2837 +2.1 2.2 transcription elongation factor GreA (RefSeq) compare
Shew_1013 +2.0 19.2 aspartate carbamoyltransferase (RefSeq) compare
Shew_2572 +2.0 10.2 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_3487 pyrE +1.9 11.0 orotate phosphoribosyltransferase (RefSeq) compare
Shew_3273 +1.9 9.1 hypothetical protein (RefSeq) compare
Shew_2895 +1.9 8.2 2-dehydropantoate 2-reductase (RefSeq) compare
Shew_3432 pdhR +1.9 6.8 transcriptional regulator PdhR (RefSeq) compare
Shew_3718 +1.9 3.3 hypothetical protein (RefSeq) compare
Shew_2642 +1.8 4.6 flavodoxin (RefSeq) compare
Shew_3431 aceE +1.8 12.6 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_1202 +1.8 7.2 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) compare
Shew_1819 +1.7 4.7 GntR family transcriptional regulator (RefSeq) compare
Shew_0383 +1.7 8.3 malate dehydrogenase (RefSeq) compare
Shew_3682 +1.7 12.5 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_1224 +1.7 14.0 sodium:dicarboxylate symporter (RefSeq) compare
Shew_2409 +1.7 3.9 short chain dehydrogenase (RefSeq) compare
Shew_1810 +1.6 6.5 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_0755 +1.6 7.4 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_3681 +1.6 10.7 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_2838 carB +1.6 7.1 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_3176 +1.5 1.5 regulatory protein GntR, HTH (RefSeq) compare
Shew_2087 +1.5 4.1 hypothetical protein (RefSeq) compare
Shew_3377 +1.5 1.3 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_1563 +1.5 8.4 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_0421 +1.5 1.4 phage shock protein C, PspC (RefSeq) compare
Shew_2839 +1.4 12.1 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_3063 +1.4 1.7 glycine cleavage system protein H (RefSeq) compare
Shew_3225 +1.4 7.8 glutathione synthetase (RefSeq) compare
Shew_3660 +1.4 11.5 glutathione reductase (RefSeq) compare
Shew_1809 +1.4 11.3 NAD-glutamate dehydrogenase (RefSeq) compare
Shew_3295 +1.4 7.5 AFG1 family ATPase (RefSeq) compare
Shew_3410 +1.3 9.2 permease (RefSeq) compare
Shew_2223 +1.3 1.2 YceI family protein (RefSeq) compare
Shew_0534 +1.3 4.6 major facilitator transporter (RefSeq) compare
Shew_2910 +1.3 1.4 hypothetical protein (RefSeq) compare
Shew_2906 +1.3 1.3 hypothetical protein (RefSeq) compare
Shew_0084 +1.3 1.6 hypothetical protein (RefSeq) compare
Shew_1078 +1.3 9.3 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_1278 +1.3 1.0 hypothetical protein (RefSeq) compare
Shew_3500 +1.3 2.2 putative endoribonuclease L-PSP (RefSeq) compare
Shew_0531 +1.2 3.9 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_3710 tdh +1.2 9.2 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_2571 +1.2 9.0 propionyl-CoA carboxylase (RefSeq) compare
Shew_2786 +1.1 1.3 sterol-binding domain-containing protein (RefSeq) compare
Shew_2367 +1.1 1.4 hypothetical protein (RefSeq) compare
Shew_2035 +1.1 2.1 hypothetical protein (RefSeq) compare
Shew_2551 +1.1 2.3 homoserine O-succinyltransferase (RefSeq) compare
Shew_1044 nhaR +1.1 3.7 transcriptional activator NhaR (RefSeq) compare
Shew_2222 +1.1 0.6 hypothetical protein (RefSeq) compare
Shew_2962 +1.1 4.6 malate dehydrogenase (RefSeq) compare
Shew_2174 +1.1 1.8 fatty acid metabolism regulator (RefSeq) compare
Shew_1287 +1.0 1.9 hypothetical protein (RefSeq) compare
Shew_1052 +1.0 4.2 GTP-binding protein LepA (RefSeq) compare
Shew_1427 +1.0 1.0 3'(2'),5'-bisphosphate nucleotidase (RefSeq) compare
Shew_2790 +1.0 1.5 nucleoside recognition domain-containing protein (RefSeq) compare
Shew_1531 grxA +1.0 2.2 glutaredoxin 1 (RefSeq) compare
Shew_3605 +1.0 0.8 cell division ATP-binding protein FtsE (RefSeq) compare
Shew_1961 +1.0 1.3 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_1210 +1.0 2.3 stationary-phase survival protein SurE (RefSeq) compare
Shew_2320 +1.0 5.6 RNA methyltransferase (RefSeq) compare
Shew_1859 +1.0 0.9 carbonate dehydratase (RefSeq) compare
Shew_2573 +1.0 6.3 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_1437 +1.0 5.1 transcriptional regulator, TyrR (RefSeq) compare
Shew_0799 +1.0 2.0 MarR family transcriptional regulator (RefSeq) compare
Shew_3600 +1.0 2.4 alpha/beta hydrolase fold (RefSeq) compare
Shew_3488 +1.0 2.6 ribonuclease PH (RefSeq) compare
Shew_3709 +0.9 5.7 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_1227 +0.9 1.0 glutamate--cysteine ligase (RefSeq) compare
Shew_3131 +0.9 6.2 poly(A) polymerase (RefSeq) compare
Shew_1304 +0.9 0.9 cyd operon protein YbgT (RefSeq) compare
Shew_3223 +0.9 1.3 deoxyribonuclease I (RefSeq) compare
Shew_1095 +0.9 1.5 ArsR family transcriptional regulator (RefSeq) compare
Shew_1011 +0.9 2.2 citrate transporter (RefSeq) compare
Shew_2544 +0.9 1.5 phosphoglucomutase/phosphomannomutase alpha/beta/subunit (RefSeq) compare
Shew_2667 +0.9 5.4 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) compare
Shew_3598 +0.9 0.6 AsnC family transcriptional regulator (RefSeq) compare
Shew_0584 +0.9 1.0 hypothetical protein (RefSeq) compare
Shew_0738 +0.9 0.7 NTPase (RefSeq) compare
Shew_1213 +0.9 1.1 RpoD family RNA polymerase sigma factor (RefSeq) compare
Shew_3602 +0.9 6.0 O-succinylbenzoate-CoA ligase (RefSeq) compare
Shew_2558 +0.9 2.9 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_1591 +0.9 2.0 bifunctional methionine sulfoxide reductase B/A protein (RefSeq) compare
Shew_3775 +0.9 1.5 thioesterase superfamily protein (RefSeq) compare
Shew_1901 +0.9 1.0 hypothetical protein (RefSeq) compare
Shew_0430 +0.8 1.8 histone family protein DNA-binding protein (RefSeq) compare
Shew_1235 +0.8 1.4 hypothetical protein (RefSeq) compare
Shew_1878 +0.8 1.6 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_2415 +0.8 0.9 major facilitator transporter (RefSeq) compare
Shew_1092 +0.8 3.7 amino acid carrier protein (RefSeq) compare
Shew_3378 +0.8 1.5 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_0047 +0.8 3.1 molybdopterin biosynthesis protein MoeB (RefSeq) compare
Shew_1050 +0.8 4.8 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_1732 +0.8 2.0 hypothetical protein (RefSeq) compare
Shew_2665 +0.8 5.5 beta-ketoacyl synthase (RefSeq) compare
Shew_0767 +0.8 3.2 ATP-dependent RNA helicase SrmB (RefSeq) compare
Shew_1851 +0.8 0.5 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_3499 +0.8 1.2 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_2664 +0.8 2.5 transcriptional regulator, putative (RefSeq) compare
Shew_2025 +0.8 3.1 leucine-responsive transcriptional regulator (RefSeq) compare
Shew_2584 +0.8 3.5 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_2668 +0.8 3.2 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_3711 +0.8 0.5 rhodanese domain-containing protein (RefSeq) compare
Shew_1920 +0.8 1.9 alpha/beta hydrolase fold (RefSeq) compare
Shew_1562 +0.8 1.7 pseudouridylate synthase (RefSeq) compare
Shew_3389 +0.7 1.0 hypothetical protein (RefSeq) compare
Shew_3268 +0.7 2.0 hypothetical protein (RefSeq) compare
Shew_0399 +0.7 2.6 methylation site containing protein (RefSeq) compare
Shew_3363 +0.7 1.2 3-dehydroquinate dehydratase, type II (RefSeq) compare
Shew_3601 +0.7 4.1 O-succinylbenzoate synthase (RefSeq) compare
Shew_1530 +0.7 1.5 porin (RefSeq) compare
Shew_1665 +0.7 0.8 peptidase S51, dipeptidase E (RefSeq) compare
Shew_1820 prpB +0.7 3.0 2-methylisocitrate lyase (RefSeq) compare
Shew_3265 +0.7 0.9 CutA1 divalent ion tolerance protein (RefSeq) compare
Shew_1994 +0.7 0.7 universal stress protein UspE (RefSeq) compare
Shew_2263 +0.7 1.1 methyl-accepting chemotaxis sensory transducer (RefSeq) compare
Shew_2008 +0.7 0.9 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_1606 +0.7 0.5 hypothetical protein (RefSeq) compare
Shew_1122 +0.7 2.9 hypothetical protein (RefSeq) compare
Shew_0086 +0.7 5.5 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_1812 +0.7 3.4 23S rRNA m(2)G2445 methyltransferase (RefSeq) compare
Shew_1176 +0.7 2.4 SecC motif-containing protein (RefSeq) compare
Shew_0371 +0.7 1.8 AraC family transcriptional regulator (RefSeq) compare
Shew_1582 +0.7 0.9 TatD family hydrolase (RefSeq) compare
Shew_2360 +0.7 2.4 D-hydroxyproline dehydrogenase (from data) compare
Shew_0446 +0.7 0.8 hypothetical protein (RefSeq) compare
Shew_1487 +0.7 1.1 hypothetical protein (RefSeq) compare
Shew_3527 +0.7 1.2 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_3289 +0.7 2.0 ribonuclease R (RefSeq) compare
Shew_1231 +0.7 1.2 ECF subfamily RNA polymerase sigma-24 factor (RefSeq) compare
Shew_2883 +0.7 1.1 BolA family protein (RefSeq) compare
Shew_2126 +0.7 2.9 ATPase (RefSeq) compare
Shew_3599 +0.7 4.0 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase (RefSeq) compare
Shew_2614 +0.7 1.4 two component LuxR family transcriptional regulator (RefSeq) compare
Shew_1386 +0.7 2.7 CheA signal transduction histidine kinase (RefSeq) compare
Shew_0396 +0.7 1.0 methylation site containing protein (RefSeq) compare
Shew_1800 +0.7 0.7 putative GAF sensor protein (RefSeq) compare
Shew_0206 +0.7 4.3 argininosuccinate lyase (RefSeq) compare
Shew_2103 def +0.7 2.0 peptide deformylase (RefSeq) compare
Shew_0842 +0.7 2.5 two component LuxR family transcriptional regulator (RefSeq) compare
Shew_0485 +0.7 1.0 cold-shock DNA-binding domain-containing protein (RefSeq) compare
Shew_2579 +0.7 2.0 thymidine kinase (RefSeq) compare
Shew_2919 +0.7 1.5 translation-associated GTPase (RefSeq) compare
Shew_3267 +0.7 2.1 sodium/hydrogen exchanger (RefSeq) compare
Shew_1784 +0.7 1.1 hypothetical protein (RefSeq) compare
Shew_1725 +0.6 0.9 curlin-associated protein (RefSeq) compare
Shew_1495 +0.6 1.4 hypothetical protein (RefSeq) compare
Shew_3189 +0.6 2.2 hypothetical protein (RefSeq) compare
Shew_1645 +0.6 2.1 sigma-54 dependent trancsriptional regulator (RefSeq) compare
Shew_0795 +0.6 0.5 hypothetical protein (RefSeq) compare
Shew_0950 +0.6 2.3 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_0757 +0.6 1.9 putative transcriptional regulator, CadC (RefSeq) compare
Shew_1673 fabG +0.6 0.5 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_1006 +0.6 0.8 ErfK/YbiS/YcfS/YnhG family protein (RefSeq) compare
Shew_0204 +0.6 2.2 ornithine carbamoyltransferase (RefSeq) compare
Shew_1094 +0.6 2.1 peptidase M28 (RefSeq) compare
Shew_2429 +0.6 0.6 hypothetical protein (RefSeq) compare
Shew_0127 +0.6 1.6 LexA repressor (RefSeq) compare
Shew_1211 +0.6 2.1 protein-L-isoaspartate O-methyltransferase (RefSeq) compare
Shew_1681 +0.6 1.4 diguanylate cyclase with PAS/PAC sensor (RefSeq) compare
Shew_2105 +0.6 0.6 methylated-DNA-(protein)-cysteine S-methyltransferase (RefSeq) compare
Shew_1865 +0.6 2.9 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_0947 +0.6 1.7 carboxypeptidase Taq (RefSeq) compare
Shew_2332 +0.6 0.6 siroheme synthase (RefSeq) compare
Shew_2135 ushA +0.6 1.8 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor (RefSeq) compare
Shew_1186 +0.6 2.6 transcriptional regulator NrdR (RefSeq) compare
Shew_3522 +0.6 1.0 hypothetical protein (RefSeq) compare
Shew_1731 +0.6 0.6 histidine triad (HIT) protein (RefSeq) compare
Shew_0740 +0.6 2.1 L-serine dehydratase 1 (RefSeq) compare
Shew_2745 +0.6 2.2 hypothetical protein (RefSeq) compare
Shew_1768 +0.6 0.7 periplasmic nitrate reductase NapE (RefSeq) compare
Shew_1903 +0.6 0.6 para-aminobenzoate synthase, subunit I (RefSeq) compare
Shew_2818 +0.6 2.2 TatD-related deoxyribonuclease (RefSeq) compare
Shew_0202 argC +0.6 4.1 N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) compare
Shew_0357 +0.6 2.9 copper ABC transporter, permease protein (RefSeq) compare
Shew_3560 +0.6 4.6 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shew_2228 +0.6 3.7 inosine kinase (RefSeq) compare
Shew_2766 +0.6 2.2 thiamine biosynthesis protein ThiI (RefSeq) compare
Shew_0400 +0.6 3.7 methylation site containing protein (RefSeq) compare
Shew_3271 +0.6 3.1 galactokinase (RefSeq) compare
Shew_2479 +0.6 2.4 methyltransferase type 11 (RefSeq) compare
Shew_3311 +0.6 4.3 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_3814 +0.6 4.7 naphthoate synthase (RefSeq) compare
Shew_1594 +0.6 1.5 RluA family pseudouridine synthase (RefSeq) compare
Shew_0787 +0.6 1.5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) compare
Shew_2444 +0.6 0.8 hypothetical protein (RefSeq) compare
Shew_0723 +0.6 1.6 ABC transporter-related protein (RefSeq) compare
Shew_1216 +0.6 1.3 regulatory protein RecX (RefSeq) compare
Shew_2554 +0.6 0.8 outer membrane protein W (RefSeq) compare
Shew_2646 +0.6 0.4 hypothetical protein (RefSeq) compare
Shew_1341 +0.6 1.9 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_3540 +0.6 3.5 NapC/NirT cytochrome c domain-containing protein (RefSeq) compare


Specific Phenotypes

None in this experiment

For Shewanella loihica PV-4 in stress experiments

For stress MreB Perturbing Compound A22 across organisms