Experiment set19S200 for Sinorhizobium meliloti 1021

Compare to:

DMSO control

200 most important genes:

  gene name fitness t score description  
SMc02766 -4.9 -13.6 tryptophan synthase subunit beta compare
SMc00236 -4.7 -3.3 Indole-3-glycerol phosphate synthase compare
SMc02767 -4.5 -7.5 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMa1635 -4.4 -2.1 hypothetical protein compare
SMc02725 -4.1 -11.4 anthranilate synthase compare
SMc00235 -3.6 -4.9 anthranilate phosphoribosyltransferase compare
SMc02765 -3.4 -9.5 tryptophan synthase subunit alpha compare
SMa1174 -3.3 -2.2 hypothetical protein compare
SMc01242 -3.0 -2.6 signal peptide protein compare
SMa0846 -2.9 -1.3 transposase, fragment compare
SMc03935 -2.9 -3.4 hypothetical protein compare
SMc01206 -2.7 -1.7 queuine tRNA-ribosyltransferase compare
SMa0955 -2.6 -2.5 GntR family transcriptional regulator compare
SMc02695 -2.5 -3.8 GTP-dependent nucleic acid-binding protein EngD compare
SMc04243 -2.5 -4.4 high-affinity zinc uptake system membrane ABC transporter protein compare
SMc01800 -2.5 -1.6 cytochrome C oxidase assembly transmembrane protein compare
SMa0740 -2.4 -1.5 hypothetical protein compare
SMc00914 -2.4 -2.3 oxidoreductase compare
SMc00427 -2.3 -2.2 peptide chain release factor RF-3 protein compare
SMc03900 -2.1 -7.1 cyclic beta-1,2-glucan ABc transporter compare
SM_b21173 -2.1 -1.5 hypothetical protein compare
SMc02906 -2.0 -0.9 hypothetical protein compare
SMc04005 -2.0 -5.8 pyruvate kinase compare
SMc03996 -2.0 -3.6 thiamine-phosphate pyrophosphorylase compare
SMc03763 -2.0 -1.4 cytosine-specific methyltransferase compare
SMc04244 -2.0 -3.7 high-affinity zinc uptake system ATP-binding ABC transporter protein compare
SMc01431 -1.9 -10.3 acetolactate synthase 3 catalytic subunit compare
SMa1073 -1.9 -1.2 TRm23b IS ATP-binding protein compare
SMc01765 -1.9 -1.8 hypothetical protein compare
SMc02435 -1.9 -1.3 methyltransferase compare
SMc00013 -1.8 -2.4 cytochrome C oxidase subunit III transmembrane protein compare
SMa1101 -1.8 -1.9 hypothetical protein compare
SMc03158 -1.8 -2.7 ABC transporter permease compare
SMc02050 -1.8 -2.1 trigger factor compare
SMc00917 -1.8 -2.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc01769 -1.7 -7.7 hypothetical protein compare
SMc03070 -1.7 -2.0 glucose-6-phosphate 1-dehydrogenase compare
SMc00298 -1.7 -2.9 methionine aminopeptidase compare
SMc00293 -1.7 -5.5 homoserine dehydrogenase compare
SMc02753 -1.7 -0.7 PTS system transporter subunit IIA compare
SMc03795 -1.7 -1.6 isopropylmalate isomerase small subunit compare
SMc02659 -1.7 -3.5 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc00963 -1.7 -1.1 hypothetical protein compare
SMa1132 -1.7 -3.8 hypothetical protein compare
SMc02561 -1.6 -1.5 hypothetical protein compare
SMc00982 -1.6 -1.9 dioxygenase compare
SMc03863 -1.6 -2.1 50S ribosomal protein L19 compare
SMa1697 -1.6 -1.0 hypothetical protein compare
SMc04346 -1.5 -4.6 ketol-acid reductoisomerase compare
SMc02245 -1.5 -1.4 dihydroorotate dehydrogenase 2 compare
SMc01124 -1.5 -6.4 PII uridylyl-transferase compare
SMa5010 -1.5 -1.2 hypothetical protein compare
SMc01036 -1.5 -2.2 hypothetical protein compare
SMa0775 -1.5 -3.1 hypothetical protein compare
SMc04245 -1.5 -6.3 high-affinity zinc uptake system ABC transporter protein compare
SMc01178 -1.5 -1.4 multidrug transmembrane resistance signal peptide protein compare
SMc04045 -1.5 -6.8 dihydroxy-acid dehydratase compare
SMc02266 -1.4 -0.9 hypothetical protein compare
SMc03069 -1.4 -1.9 6-phosphogluconolactonase compare
SM_b21174 -1.4 -2.7 phosphate uptake ABC transporter permease compare
SMc01012 -1.4 -1.2 hypothetical protein compare
SMc00554 -1.4 -5.4 amidophosphoribosyltransferase compare
SMc03850 -1.4 -0.8 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc00821 -1.4 -0.8 hypothetical protein compare
SMc00349 -1.3 -4.2 GTP-binding protein LepA compare
SMc00351 -1.3 -1.0 hypothetical protein compare
SMc00540 -1.3 -1.4 hypothetical protein compare
SMc03066 -1.3 -1.0 hypothetical protein compare
SM_b20810 -1.3 -4.7 membrane-located cell surface saccharide acetylase compare
SMc02055 -1.3 -1.2 phytoene synthase compare
SMc00329 -1.3 -1.2 iron response regulator protein compare
SMa1907 -1.3 -2.1 hypothetical protein compare
SMc00876 -1.3 -3.0 ATP-binding MRP protein compare
SMc04003 -1.3 -2.0 50S ribosomal protein L36 compare
SMc00993 -1.3 -5.7 phosphoribosylamine--glycine ligase compare
SMc00981 -1.3 -2.7 ferredoxin protein compare
SMc00505 -1.2 -2.2 hypothetical protein compare
SMc00458 -1.2 -5.9 transcriptional regulator compare
SMc00353 -1.2 -1.3 transmembrane protein compare
SMc02985 -1.2 -0.8 hypothetical protein compare
SMc04088 -1.2 -5.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc00412 -1.2 -0.8 orotidine 5'-phosphate decarboxylase compare
SMc02155 -1.2 -7.3 hypothetical protein compare
SMc02755 -1.2 -4.3 S-adenosyl-L-homocysteine hydrolase compare
SMc03159 -1.2 -2.1 ABC transporter ATP-binding protein compare
SMc00450 -1.2 -0.8 protoheme IX farnesyltransferase compare
SMc01939 -1.2 -1.5 urease subunit beta compare
SMc02232 -1.2 -0.8 hypothetical protein compare
SM_b21177 -1.1 -3.9 phosphate uptake ABC transporter ATP-binding protein compare
SMa5033 -1.1 -1.0 hypothetical protein compare
SMc00495 -1.1 -3.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc01004 -1.1 -4.7 phosphoribosyl-AMP cyclohydrolase compare
SMc02165 -1.1 -1.1 orotate phosphoribosyltransferase compare
SMc00175 -1.1 -4.0 ABC transporter ATP-binding protein compare
SMc04085 -1.1 -1.7 hypothetical protein compare
SMc00493 -1.1 -2.9 phosphoribosylformylglycinamidine synthase I compare
SMc00302 -1.1 -1.6 hypothetical protein compare
SMc01183 -1.1 -0.9 LexA repressor compare
SMc01112 -1.1 -4.3 hypothetical protein compare
SMc04441 -1.1 -1.7 hypothetical protein compare
SMc00576 -1.1 -1.9 hypothetical protein compare
SMc00174 -1.1 -4.2 hypothetical protein compare
SMc02833 -1.1 -1.0 penicillin-insensitive murein endopeptidase compare
SMc04232 -1.1 -1.5 glycine rich transmembrane protein compare
SMc00286 -1.1 -1.3 hemolysin-type calcium-binding protein compare
SMa0545 -1.0 -2.0 hypothetical protein compare
SMc04327 -1.0 -0.7 hypothetical protein compare
SMc04382 -1.0 -8.4 beta-(1,2)-glucan production associated transmembrane protein compare
SMc03157 -1.0 -6.0 outer membrane lipoprotein transmembrane compare
SMa1700 -1.0 -0.9 hypothetical protein compare
SMc02570 -1.0 -3.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc01836 -1.0 -1.3 hypothetical protein compare
SMc03046 -1.0 -2.5 transcriptional regulator compare
SMc00188 -0.9 -3.3 cytochrome B transmembrane protein compare
SMa0851 -0.9 -1.5 NodH sulfotransferase compare
SMc02558 -0.9 -2.7 hypothetical protein compare
SMc01099 -0.9 -1.5 tRNA pseudouridine synthase A compare
SMc01223 -0.9 -2.6 transcriptional regulator compare
SMa1223 -0.9 -2.0 hypothetical protein compare
SMc04383 -0.9 -2.3 putative hydrolase, required for lysine catabolism (from data) compare
SMc00615 -0.9 -5.1 phosphoribosylaminoimidazole synthetase compare
SMc02737 -0.9 -2.2 glycine betaine-binding ABC transporter protein compare
SMc00488 -0.9 -6.4 phosphoribosylformylglycinamidine synthase II compare
SMc01845 -0.9 -1.1 transglycosylase transmembrane protein compare
SMc01723 -0.9 -1.4 hypothetical protein compare
SMc02149 -0.9 -1.4 hypothetical protein compare
SMc00614 -0.9 -3.0 phosphoribosylglycinamide formyltransferase compare
SMc00010 -0.9 -1.0 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc00320 -0.9 -4.0 ribosome-binding factor A compare
SMc00647 -0.9 -2.6 ribosomal large subunit pseudouridine synthase compare
SMc01568 -0.9 -1.4 hypothetical protein compare
SMa1365 -0.8 -0.8 ATP-binding protein compare
SMc02280 -0.8 -1.1 hypothetical protein compare
SMc01595 -0.8 -1.0 sensor histidine kinase transmembrane protein compare
SMa1770 -0.8 -1.0 hypothetical protein compare
SMc02434 -0.8 -0.8 hypothetical protein compare
SMc01461 -0.8 -2.7 DNA helicase II protein compare
SMc02520 -0.8 -0.8 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) (from data) compare
SM_b20474 -0.8 -1.6 hypothetical protein compare
SM_b20563 -0.8 -1.3 hypothetical protein compare
SMc02115 -0.8 -0.3 hypothetical protein compare
SMc01007 -0.8 -1.2 hypothetical protein compare
SM_b20837 -0.8 -1.8 hypothetical protein compare
SMc03182 -0.8 -3.1 pH adaptation potassium efflux system E transmembrane protein compare
SMc00622 -0.8 -3.8 ribonuclease D protein compare
SMc02572 -0.8 -2.1 imidazole glycerol phosphate synthase subunit HisH compare
SMc00725 -0.8 -2.0 argininosuccinate lyase compare
SM_b21156 -0.8 -2.2 hypothetical protein compare
SMa1160 -0.8 -2.3 hypothetical protein compare
SMc00494 -0.8 -1.3 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc02425 -0.8 -1.4 transcriptional regulator compare
SMa1960 -0.8 -2.0 hypothetical protein compare
SMa0052 -0.8 -1.7 hypothetical protein compare
SM_b20484 -0.8 -2.5 sugar ABC transporter substrate-binding protein compare
SMc01709 -0.8 -2.4 signal peptide protein compare
SMc02866 -0.8 -2.4 transcriptional regulator compare
SMc04001 -0.8 -0.8 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMa0357 -0.8 -1.5 hypothetical protein compare
SMc02647 -0.8 -0.7 transcriptional regulator compare
SMc00012 -0.7 -1.2 cytochrome C oxidase assembly protein compare
SM_b20773 -0.7 -2.5 GntR family transcriptional regulator compare
SMa0050 -0.7 -2.0 hypothetical protein compare
SM_b21175 -0.7 -1.5 phosphate uptake ABC transporter permease compare
SMc03930 -0.7 -0.9 sarcosine oxidase subunit gamma compare
SMa0894 -0.7 -1.6 hypothetical protein compare
SMc03941 -0.7 -1.7 hypothetical protein compare
SMc02861 -0.7 -1.3 phosphate transporter compare
SMc01850 -0.7 -0.8 hypothetical protein compare
SMc01635 -0.7 -1.8 oxidoreductase compare
SMc00239 -0.7 -0.7 hypothetical protein compare
SM_b21145 -0.7 -2.1 choline uptake ABC transporter permease compare
SMc04002 -0.7 -2.6 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc01207 -0.7 -1.1 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMa1597 -0.7 -1.5 Pilus assembly chaperone compare
SMc02897 -0.7 -0.9 cytochrome C transmembrane protein compare
SMa0312 -0.7 -1.6 hypothetical protein compare
SM_b21176 -0.7 -2.0 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc01441 -0.7 -1.4 membrane bound protease compare
SMc00147 -0.7 -1.6 hypothetical protein compare
SMa0809 -0.7 -1.9 hypothetical protein compare
SMc01153 -0.7 -1.1 enoyl-CoA hydratase compare
SMc00976 -0.7 -1.9 enoyl-CoA hydratase compare
SMc00176 -0.7 -2.6 hypothetical protein compare
SMa1052 -0.7 -0.8 hypothetical protein compare
SMc04456 -0.7 -1.7 chaperone protein compare
SMc04239 -0.7 -0.8 hypothetical protein compare
SMc02166 -0.7 -2.1 dihydroorotase compare
SMc02143 -0.7 -1.7 phosphate ABC transporter permease compare
SMa0754 -0.7 -1.4 hypothetical protein compare
SM_b21167 -0.7 -2.5 reverse transcriptasematurase compare
SM_b20884 -0.7 -1.7 hypothetical protein compare
SM_b20880 -0.7 -2.7 ATP-dependent RNA helicase compare
SM_b20809 -0.7 -3.1 arabinose-5-phosphate isomerase compare
SMc00565 -0.7 -1.1 50S ribosomal protein L9 compare
SMc02980 -0.7 -1.0 hypothetical protein compare
SMc00419 -0.7 -1.4 glutathione synthetase compare
SMc01578 -0.7 -4.2 aspartate aminotransferase compare
SMc02238 -0.7 -0.6 hypothetical protein compare
SM_b20549 -0.7 -1.4 hypothetical protein compare
SMc00496 -0.7 -1.0 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Sinorhizobium meliloti 1021 in dmso control experiments

For dmso control Dimethyl Sulfoxide across organisms