Experiment set19IT029 for Pseudomonas stutzeri RCH2

Compare to:

Defined media with L-tyrosine disodium salt

200 most detrimental genes:

  gene name fitness t score description  
Psest_0285 +6.5 25.0 pilus retraction protein PilT compare
Psest_1765 +5.7 25.4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_1721 +5.7 15.1 Flagellar biosynthesis/type III secretory pathway protein compare
Psest_1729 +5.6 15.4 flagellar motor switch protein FliM compare
Psest_1731 +5.6 13.9 flagellar biosynthetic protein FliO compare
Psest_2333 +5.6 6.9 Protein of unknown function (DUF3359). compare
Psest_2961 +5.5 15.0 Flagellar basal-body P-ring protein compare
Psest_1718 +5.4 12.6 flagellar hook-basal body complex protein FliE compare
Psest_1734 +5.3 14.4 flagellar biosynthetic protein FliR compare
Psest_1737 +5.3 16.2 flagellar biosynthesis protein FlhA compare
Psest_2965 +5.3 36.1 fagellar hook-basal body proteins compare
Psest_1722 +5.3 29.1 flagellar protein export ATPase FliI compare
Psest_1723 +5.2 13.1 flagellar export protein FliJ compare
Psest_1735 +5.2 17.9 flagellar biosynthetic protein FlhB compare
Psest_1720 +5.1 23.3 flagellar motor switch protein FliG compare
Psest_1740 +5.1 20.8 RNA polymerase sigma factor, FliA/WhiG family compare
Psest_1732 +5.1 14.6 flagellar biosynthetic protein FliP compare
Psest_2962 +5.0 19.2 Flagellar basal body L-ring protein compare
Psest_1719 +4.9 15.5 flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF) compare
Psest_2960 +4.9 13.8 flagellar rod assembly protein/muramidase FlgJ compare
Psest_2963 +4.9 17.1 flagellar basal-body rod protein FlgG, Gram-negative bacteria compare
Psest_1733 +4.7 8.7 flagellar biosynthetic protein FliQ compare
Psest_2964 +4.7 15.1 flagellar basal-body rod protein FlgF compare
Psest_2973 +4.4 11.1 Flagellar biosynthesis/type III secretory pathway chaperone compare
Psest_2971 +4.3 13.9 flagella basal body P-ring formation protein FlgA compare
Psest_2959 +4.2 26.0 flagellar hook-associated protein FlgK compare
Psest_1728 +4.2 7.6 Flagellar basal body-associated protein compare
Psest_2966 +4.2 10.7 Flagellar hook capping protein compare
Psest_1743 +4.2 13.6 Chemotaxis protein histidine kinase and related kinases compare
Psest_2958 +4.2 27.1 flagellar hook-associated protein 3 compare
Psest_1746 +3.9 13.2 Flagellar motor protein compare
Psest_2969 +3.8 13.7 Methylase of chemotaxis methyl-accepting proteins compare
Psest_2507 +3.7 22.5 Flagellin and related hook-associated proteins compare
Psest_1744 +3.6 13.0 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain compare
Psest_1741 +3.5 6.0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3301 +3.4 7.2 Predicted transcriptional regulator, BolA superfamily compare
Psest_1749 +3.3 11.1 Chemotaxis signal transduction protein compare
Psest_1738 +3.3 9.2 flagellar biosynthetic protein FlhF compare
Psest_1745 +3.2 9.7 Flagellar motor component compare
Psest_2504 +3.1 9.3 flagellar biosynthetic protein FliS compare
Psest_0496 +3.1 11.4 flagellar motor stator protein MotA compare
Psest_1742 +3.0 8.8 Chemotaxis protein compare
Psest_0497 +3.0 11.9 Flagellar motor protein compare
Psest_0445 +2.8 15.4 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_2505 +2.6 13.2 Flagellar capping protein compare
Psest_1748 +2.3 6.9 CheW-like domain. compare
Psest_3122 +1.7 5.5 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Psest_3720 +1.6 12.4 penicillin-binding protein, 1A family compare
Psest_3168 +1.6 2.2 Molybdopterin converting factor, large subunit compare
Psest_2285 +1.5 3.0 ATP-dependent protease La compare
Psest_1747 +1.5 6.1 ATPases involved in chromosome partitioning compare
Psest_2522 +1.5 8.7 PAS domain S-box compare
Psest_3237 +1.4 2.4 hypothetical protein compare
Psest_2232 +1.4 8.1 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_1695 +1.4 2.5 Tfp pilus assembly protein PilZ compare
Psest_1017 +1.4 6.7 Protein of unknown function (DUF3426). compare
Psest_2323 +1.3 8.3 Uncharacterized protein conserved in archaea compare
Psest_0988 +1.3 2.7 Protein of unknown function (DUF2845). compare
Psest_0066 +1.3 2.8 Protein of unknown function (DUF3060). compare
Psest_2764 +1.3 1.0 hypothetical protein compare
Psest_0193 +1.2 1.0 conserved hypothetical protein compare
Psest_0575 +1.2 1.2 HrpA-like helicases compare
Psest_4154 +1.2 1.8 flagella basal body P-ring formation protein FlgA compare
Psest_3637 +1.2 2.2 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases compare
Psest_3296 +1.2 1.5 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain compare
Psest_1115 +1.1 2.2 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_1111 +1.1 2.2 Flp pilus assembly protein TadD, contains TPR repeats compare
Psest_2293 +1.1 1.6 hypothetical protein compare
Psest_1215 +1.1 1.3 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) compare
Psest_0656 +1.1 2.6 Methyl-accepting chemotaxis protein compare
Psest_3719 +1.1 5.6 type IV pilus assembly protein PilM compare
Psest_3718 +1.1 3.1 Tfp pilus assembly protein PilN compare
Psest_2240 +1.1 1.8 hypothetical protein compare
Psest_2324 +1.0 7.8 hypothetical protein compare
Psest_4350 +1.0 2.6 Transcriptional regulators of sugar metabolism compare
Psest_4300 +1.0 2.3 PAS domain S-box compare
Psest_2442 +1.0 1.0 hypothetical protein compare
Psest_0139 +1.0 3.7 ABC-type histidine transport system, ATPase component compare
Psest_3715 +1.0 6.8 type IV pilus secretin (or competence protein) PilQ compare
Psest_1144 +0.9 1.2 AmpG-related permease compare
Psest_3717 +0.9 3.6 Tfp pilus assembly protein PilO compare
Psest_1204 +0.9 2.0 Transcriptional regulators compare
Psest_1505 +0.9 0.9 Organic radical activating enzymes compare
Psest_4097 +0.9 5.3 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_0987 +0.9 1.5 Predicted periplasmic or secreted lipoprotein compare
Psest_0054 +0.9 3.1 hypothetical protein compare
Psest_2970 +0.9 6.5 Chemotaxis signal transduction protein compare
Psest_2586 +0.9 7.1 FimV N-terminal domain compare
Psest_3287 +0.9 3.1 Type II secretory pathway, component PulF compare
Psest_0186 +0.9 2.4 Protein-disulfide isomerase compare
Psest_2506 +0.9 3.7 Uncharacterized flagellar protein FlaG compare
Psest_1631 +0.9 1.2 Uncharacterized conserved small protein compare
Psest_3129 +0.9 0.8 tyrosine recombinase XerD compare
Psest_2265 +0.9 1.5 Outer membrane protein compare
Psest_4370 +0.9 1.4 Multisubunit Na+/H+ antiporter, MnhC subunit compare
Psest_4220 +0.8 0.8 Protein of unknown function (DUF2782). compare
Psest_2976 +0.8 1.3 hypothetical protein compare
Psest_3496 +0.8 0.9 Predicted metal-binding protein compare
Psest_0093 +0.8 2.2 Uncharacterized enzyme of phosphonate metabolism compare
Psest_0558 +0.8 0.7 urease, beta subunit compare
Psest_3435 +0.8 1.6 hypothetical protein compare
Psest_2756 +0.8 0.8 hypothetical protein compare
Psest_2613 +0.8 0.8 hypothetical protein compare
Psest_2448 +0.8 2.4 AraC-type DNA-binding domain-containing proteins compare
Psest_3890 +0.8 1.2 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_3662 +0.8 1.3 DnaJ-domain-containing proteins 1 compare
Psest_0814 +0.8 1.2 MoxR-like ATPases compare
Psest_4049 +0.8 1.2 hypothetical protein compare
Psest_1576 +0.8 3.9 Periplasmic glucans biosynthesis protein compare
Psest_3288 +0.8 4.4 type IV-A pilus assembly ATPase PilB compare
Psest_0705 +0.8 5.4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_2719 +0.8 1.5 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_4183 +0.8 1.4 PilZ domain. compare
Psest_1260 +0.8 2.7 type IV pilus biogenesis/stability protein PilW compare
Psest_3743 +0.8 2.9 Regulator of sigma D compare
Psest_0073 +0.8 2.9 ABC-type multidrug transport system, ATPase and permease components compare
Psest_3664 +0.8 0.8 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_3716 +0.8 4.3 Tfp pilus assembly protein PilP compare
Psest_3289 +0.8 3.5 prepilin-type N-terminal cleavage/methylation domain compare
Psest_3692 +0.8 2.1 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases compare
Psest_1679 +0.7 0.7 ribonuclease, Rne/Rng family compare
Psest_3800 +0.7 2.3 3-hydroxyacyl-CoA dehydrogenase compare
Psest_4307 +0.7 1.5 ABC-type Zn2+ transport system, periplasmic component/surface adhesin compare
Psest_1145 +0.7 1.5 Predicted methylated DNA-protein cysteine methyltransferase compare
Psest_3828 +0.7 0.8 zinc-binding alcohol dehydrogenase family protein compare
Psest_2668 +0.7 1.9 Lactoylglutathione lyase and related lyases compare
Psest_3792 +0.7 1.6 Putative translation initiation inhibitor, yjgF family compare
Psest_4044 +0.7 2.0 type I site-specific deoxyribonuclease, HsdR family compare
Psest_1661 +0.7 1.1 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_1601 +0.7 1.0 Signal transduction histidine kinase compare
Psest_2503 +0.7 2.5 hypothetical protein compare
Psest_0796 +0.7 1.4 ABC-type transport system involved in multi-copper enzyme maturation, permease component compare
Psest_1516 +0.7 1.5 Uncharacterized lipoprotein compare
Psest_0877 +0.7 2.7 Restriction endonuclease compare
Psest_2424 +0.7 1.4 K+ transport systems, NAD-binding component compare
Psest_0400 +0.7 2.1 Geranylgeranyl pyrophosphate synthase compare
Psest_4274 +0.7 1.2 hypothetical protein compare
Psest_2325 +0.7 3.2 alpha-L-glutamate ligase-related protein compare
Psest_3754 +0.7 1.4 Uncharacterized protein involved in response to NO compare
Psest_0730 +0.7 3.2 O-6-methylguanine DNA methyltransferase compare
Psest_0844 +0.7 1.9 High-affinity Fe2+/Pb2+ permease compare
Psest_2407 +0.7 1.3 nitrite reductase [NAD(P)H], small subunit compare
Psest_2123 +0.7 1.1 fusion of gluconokinase (EC 2.7.1.12) and the small permease component of the D-gluconate TRAP transporter (from data) compare
Psest_0514 +0.7 3.3 lytic murein transglycosylase B compare
Psest_2946 +0.7 1.4 septum site-determining protein MinD compare
Psest_1963 +0.7 2.0 Peptidase inhibitor I78 family. compare
Psest_2513 +0.7 2.3 Predicted membrane protein compare
Psest_0300 +0.7 3.7 Methyl-accepting chemotaxis protein compare
Psest_2001 +0.7 0.8 2-phosphoglycolate phosphatase, prokaryotic compare
Psest_1354 +0.7 0.8 Uncharacterized protein conserved in bacteria compare
Psest_3001 +0.7 2.0 molybdenum ABC transporter, ATP-binding protein compare
Psest_1878 +0.7 1.2 Uncharacterized protein conserved in bacteria compare
Psest_1479 +0.7 2.0 NAD(P)H:quinone oxidoreductase, type IV compare
Psest_1160 +0.7 1.8 Uncharacterized conserved protein compare
Psest_4170 +0.7 1.2 Flagellar biosynthesis/type III secretory pathway protein compare
Psest_0061 +0.7 1.1 hypothetical protein compare
Psest_3474 +0.7 1.4 Short-chain dehydrogenases of various substrate specificities compare
Psest_3533 +0.7 2.0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_3399 +0.6 0.8 Uncharacterized protein conserved in bacteria compare
Psest_2015 +0.6 1.5 Type II secretory pathway, component PulD compare
Psest_2130 +0.6 1.2 exodeoxyribonuclease III compare
Psest_2304 +0.6 0.6 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Psest_3408 +0.6 3.4 Predicted transcriptional regulators compare
Psest_2899 +0.6 0.7 hypothetical protein compare
Psest_3854 +0.6 2.7 ABC-type branched-chain amino acid transport systems, ATPase component compare
Psest_2177 +0.6 1.6 Protein of unknown function (DUF1652). compare
Psest_0209 +0.6 1.2 membrane protein AbrB duplication compare
Psest_4291 +0.6 1.7 agmatine deiminase compare
Psest_1920 +0.6 0.5 Uncharacterized protein conserved in bacteria compare
Psest_1763 +0.6 1.7 hypothetical protein compare
Psest_3521 +0.6 1.9 H+/gluconate symporter and related permeases compare
Psest_2953 +0.6 0.7 Histone acetyltransferase compare
Psest_1958 +0.6 1.7 Glutaredoxin-like domain (DUF836). compare
Psest_4273 +0.6 3.2 Lysophospholipase compare
Psest_2557 +0.6 0.9 Protein of unknown function (DUF2474). compare
Psest_3744 +0.6 2.4 Disulfide bond formation protein DsbB compare
Psest_0491 +0.6 3.5 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_0510 +0.6 1.6 iojap-like ribosome-associated protein compare
Psest_0115 +0.6 0.7 Predicted integral membrane protein compare
Psest_4411 +0.6 1.7 Phage terminase, small subunit compare
Psest_1947 +0.6 0.4 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_1750 +0.6 0.8 Protein of unknown function (DUF2802). compare
Psest_1554 +0.6 1.9 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Psest_3286 +0.6 2.2 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases compare
Psest_0922 +0.6 0.9 alkylhydroperoxidase AhpD family core domain compare
Psest_3421 +0.6 0.8 hypothetical protein compare
Psest_3333 +0.6 2.0 K+-dependent Na+/Ca+ exchanger related-protein compare
Psest_0681 +0.6 2.6 DNA mismatch repair protein MutL compare
Psest_0837 +0.6 1.0 Putative lipid carrier protein compare
Psest_3933 +0.6 3.1 hypothetical protein compare
Psest_1843 +0.6 0.8 Uncharacterized Fe-S protein compare
Psest_0201 +0.6 2.4 PAS domain S-box compare
Psest_0117 +0.6 2.5 Uncharacterized protein conserved in bacteria (DUF2063). compare
Psest_1556 +0.6 1.3 hypothetical protein compare
Psest_2383 +0.6 2.3 Predicted transcriptional regulators compare
Psest_2565 +0.6 0.8 Transcriptional regulator compare
Psest_1498 +0.6 1.0 tol-pal system-associated acyl-CoA thioesterase compare
Psest_0414 +0.6 1.8 biotin biosynthesis protein BioC compare
Psest_2525 +0.6 1.0 cytochrome c oxidase, cbb3-type, subunit II compare
Psest_1067 +0.6 1.9 hypothetical protein compare


Specific Phenotypes

For 17 genes in this experiment

For nutrient L-tyrosine disodium salt in Pseudomonas stutzeri RCH2

For nutrient L-tyrosine disodium salt across organisms