Experiment set19IT025 for Pseudomonas stutzeri RCH2

Compare to:

Defined media with L-Histidine

200 most important genes:

  gene name fitness t score description  
Psest_0062 -6.3 -6.1 tryptophan synthase, alpha subunit compare
Psest_3647 -6.1 -4.2 Indole-3-glycerol phosphate synthase compare
Psest_0508 -6.0 -7.2 gamma-glutamyl phosphate reductase compare
Psest_3650 -5.9 -5.7 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0279 -5.9 -5.7 methionine biosynthesis protein MetW compare
Psest_3648 -5.7 -4.0 anthranilate phosphoribosyltransferase compare
Psest_3866 -5.6 -14.1 threonine ammonia-lyase, biosynthetic, long form compare
Psest_0852 -5.5 -9.1 glucose-6-phosphate 1-dehydrogenase compare
Psest_0855 -5.4 -5.2 NAD-dependent aldehyde dehydrogenases compare
Psest_2584 -5.4 -3.7 Phosphoribosylanthranilate isomerase compare
Psest_1037 -5.3 -3.5 acetolactate synthase, small subunit compare
Psest_0063 -5.1 -7.9 tryptophan synthase, beta subunit compare
Psest_1895 -5.1 -8.5 Signal transduction histidine kinase compare
Psest_1898 -5.1 -11.3 ABC-type sugar transport system, permease component compare
Psest_3384 -5.0 -7.7 glutamate 5-kinase compare
Psest_1897 -5.0 -14.7 ABC-type sugar transport systems, permease components compare
Psest_2578 -4.8 -11.5 O-succinylhomoserine sulfhydrylase compare
Psest_3649 -4.7 -9.0 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0280 -4.6 -13.9 homoserine O-acetyltransferase compare
Psest_2591 -4.3 -2.9 3-isopropylmalate dehydratase, large subunit compare
Psest_0850 -4.2 -12.0 glucokinase, proteobacterial type compare
Psest_4085 -4.1 -19.0 Biotin carboxylase compare
Psest_0849 -4.0 -14.1 6-phosphogluconate dehydratase compare
Psest_2590 -4.0 -1.7 3-isopropylmalate dehydratase, small subunit compare
Psest_0313 -3.9 -5.3 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_3818 -3.9 -9.0 endoribonuclease L-PSP, putative compare
Psest_4084 -3.9 -17.7 oxaloacetate decarboxylase alpha subunit compare
Psest_4086 -3.8 -12.8 Transcriptional regulator compare
Psest_1772 -3.8 -4.5 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_1899 -3.8 -6.3 ABC-type sugar transport systems, ATPase components compare
Psest_3226 -3.8 -1.1 Predicted membrane protein compare
Psest_2589 -3.6 -11.4 3-isopropylmalate dehydrogenase compare
Psest_3546 -3.2 -1.4 Phosphatidylglycerophosphatase A and related proteins compare
Psest_0853 -2.9 -6.4 6-phosphogluconolactonase compare
Psest_4219 -2.8 -3.2 DNA polymerase I compare
Psest_3322 -2.7 -18.8 TIGR02099 family protein compare
Psest_1896 -2.7 -3.3 ABC-type sugar transport system, periplasmic component compare
Psest_2579 -2.7 -1.8 amidophosphoribosyltransferase compare
Psest_0999 -2.6 -1.8 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_1295 -2.5 -5.0 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_2025 -2.5 -1.6 cold shock domain protein CspD compare
Psest_3190 -2.4 -6.0 pyruvate kinase compare
Psest_1492 -2.3 -9.9 DNA-binding ferritin-like protein (oxidative damage protectant) compare
Psest_2988 -2.3 -6.8 aspartate kinase, monofunctional class compare
Psest_4088 -2.3 -4.9 Transcriptional regulators compare
Psest_1012 -2.3 -4.9 Signal transduction histidine kinase compare
Psest_0498 -2.2 -2.0 ribosome small subunit-dependent GTPase A compare
Psest_1814 -2.2 -15.0 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_2329 -2.2 -12.7 Transcriptional regulator compare
Psest_3862 -2.2 -12.1 phosphoenolpyruvate-protein phosphotransferase compare
Psest_1473 -2.1 -7.0 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_0489 -2.0 -1.3 phosphoserine phosphatase SerB compare
Psest_2018 -1.9 -2.5 Uncharacterized conserved protein compare
Psest_1686 -1.9 -5.3 fatty acid/phospholipid synthesis protein PlsX compare
Psest_3317 -1.9 -5.3 Phosphotransferase System HPr (HPr) Family compare
Psest_3047 -1.9 -1.4 methionyl-tRNA synthetase/methionyl-tRNA synthetase C-terminal region/beta chain compare
Psest_1474 -1.9 -1.8 phosphoribosylaminoimidazole synthetase compare
Psest_2238 -1.9 -3.7 hypothetical protein compare
Psest_0359 -1.8 -3.1 Transcriptional regulators compare
Psest_1013 -1.8 -1.8 phosphoribosylamine--glycine ligase compare
Psest_2975 -1.8 -2.0 tRNA_Arg_CCT compare
Psest_3178 -1.7 -2.8 formyltetrahydrofolate deformylase compare
Psest_2872 -1.7 -2.2 protein RecA compare
Psest_0511 -1.7 -2.5 rRNA large subunit m3Psi methyltransferase RlmH compare
Psest_3159 -1.7 -4.4 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_1595 -1.6 -1.5 Copper chaperone compare
Psest_3767 -1.6 -4.0 tyrosine recombinase XerC compare
Psest_1496 -1.6 -1.2 Holliday junction DNA helicase, RuvA subunit compare
Psest_4298 -1.6 -1.2 Response regulator containing a CheY-like receiver domain and a GGDEF domain compare
Psest_2532 -1.6 -2.5 Uncharacterized protein conserved in bacteria compare
Psest_4003 -1.6 -4.2 TIGR00153 family protein compare
Psest_0260 -1.5 -2.0 Cell division protein compare
Psest_0958 -1.5 -6.1 Oligoketide cyclase/lipid transport protein compare
Psest_4201 -1.5 -2.3 general secretion pathway protein F compare
Psest_1510 -1.5 -3.2 Putative Zn-dependent protease, contains TPR repeats compare
Psest_3998 -1.5 -6.4 glutamate--cysteine ligase compare
Psest_1082 -1.4 -1.6 Enoyl-CoA hydratase/carnithine racemase compare
Psest_2968 -1.4 -4.5 flagellar basal-body rod protein FlgB compare
Psest_3927 -1.4 -5.0 thiazole biosynthesis/tRNA modification protein ThiI compare
Psest_1518 -1.4 -2.5 tRNA_Ser_CGA compare
Psest_3803 -1.4 -1.3 DNA repair protein radc compare
Psest_1974 -1.4 -2.4 integration host factor, alpha subunit compare
Psest_1428 -1.4 -2.9 Threonine dehydrogenase and related Zn-dependent dehydrogenases compare
Psest_3438 -1.4 -5.6 Glutamate dehydrogenase/leucine dehydrogenase compare
Psest_0715 -1.3 -9.2 NADH dehydrogenase, FAD-containing subunit compare
Psest_2967 -1.3 -1.7 flagellar basal-body rod protein FlgC compare
Psest_0716 -1.3 -2.2 Protein of unknown function (DUF3094). compare
Psest_1805 -1.3 -1.7 integration host factor, beta subunit compare
Psest_1417 -1.3 -1.2 hypothetical protein compare
Psest_0097 -1.3 -2.2 phosphonates metabolism transcriptional regulator PhnF compare
Psest_3174 -1.2 -9.5 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase compare
Psest_1377 -1.2 -5.3 hypothetical protein compare
Psest_3766 -1.2 -1.7 Uncharacterized protein conserved in bacteria compare
Psest_4177 -1.2 -1.8 flagellar biosynthetic protein FliP compare
Psest_1001 -1.2 -1.8 hypothetical protein compare
Psest_3338 -1.2 -1.9 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_2088 -1.2 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_3843 -1.2 -5.5 4-hydroxybenzoate synthetase (chorismate lyase) compare
Psest_2637 -1.2 -1.2 putative methyltransferase, YaeB/AF_0241 family compare
Psest_1277 -1.2 -7.0 2-isopropylmalate synthase, yeast type compare
Psest_0078 -1.2 -1.4 hypothetical protein compare
Psest_0325 -1.2 -6.6 Putative threonine efflux protein compare
Psest_0175 -1.1 -4.9 Xaa-Pro aminopeptidase compare
Psest_2545 -1.1 -2.7 recombination protein RecR compare
Psest_2470 -1.1 -3.0 hypothetical protein compare
Psest_1879 -1.1 -2.2 Trk-type K+ transport systems, membrane components compare
Psest_1920 -1.1 -0.7 Uncharacterized protein conserved in bacteria compare
Psest_1282 -1.1 -1.7 Amidases related to nicotinamidase compare
Psest_2253 -1.1 -2.0 small redox-active disulfide protein 2 compare
Psest_2454 -1.1 -2.7 Rhodanese-related sulfurtransferase compare
Psest_2645 -1.1 -3.8 Transcriptional regulator compare
Psest_1960 -1.0 -1.8 Bacterial protein of unknown function (DUF903). compare
Psest_3213 -1.0 -3.7 acetate kinase compare
Psest_2953 -1.0 -1.5 Histone acetyltransferase compare
Psest_3502 -1.0 -2.7 flavoprotein, HI0933 family/uncharacterized flavoprotein, PP_4765 family compare
Psest_2809 -1.0 -2.5 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_1540 -1.0 -1.2 biotin-dependent carboxylase uncharacterized domain compare
Psest_3853 -1.0 -2.6 ABC-type branched-chain amino acid transport systems, ATPase component compare
Psest_0243 -1.0 -1.0 hypothetical protein compare
Psest_2901 -1.0 -1.7 hypothetical protein compare
Psest_2561 -1.0 -0.9 hypothetical protein compare
Psest_3890 -1.0 -1.4 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_1463 -1.0 -0.9 SufE protein probably involved in Fe-S center assembly compare
Psest_2526 -1.0 -5.0 cytochrome c oxidase, cbb3-type, subunit III compare
Psest_4287 -1.0 -4.6 Predicted glutamine amidotransferases compare
Psest_3351 -1.0 -2.7 peptide chain release factor 3 compare
Psest_3391 -1.0 -1.8 Uncharacterized protein conserved in bacteria compare
Psest_1663 -1.0 -2.3 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes compare
Psest_1472 -1.0 -4.2 Protein of unknown function (DUF3108). compare
Psest_2775 -1.0 -1.7 Glycerol-3-phosphate dehydrogenase compare
Psest_1305 -1.0 -2.0 Heat shock protein compare
Psest_3365 -1.0 -2.4 Predicted membrane protein compare
Psest_3810 -1.0 -0.6 orotate phosphoribosyltransferase compare
Psest_1598 -0.9 -2.5 heavy metal response regulator compare
Psest_1782 -0.9 -1.5 Predicted transcriptional regulators compare
Psest_2446 -0.9 -1.7 acetyl-CoA acetyltransferases compare
Psest_2714 -0.9 -1.3 7-cyano-7-deazaguanine reductase compare
Psest_4325 -0.9 -1.6 hypothetical protein compare
Psest_0662 -0.9 -1.5 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_0442 -0.9 -1.5 ATPases of the AAA+ class compare
Psest_3872 -0.9 -4.8 FAD/FMN-containing dehydrogenases compare
Psest_1185 -0.9 -2.5 heavy metal response regulator compare
Psest_1161 -0.9 -1.7 E3 Ubiquitin ligase. compare
Psest_3239 -0.9 -2.8 hypothetical protein compare
Psest_1997 -0.9 -1.8 6-phosphogluconolactonase compare
Psest_4152 -0.9 -2.7 flagellar basal-body rod protein FlgC compare
Psest_1000 -0.9 -4.9 PAS domain S-box compare
Psest_3214 -0.9 -3.8 phosphate acetyltransferase compare
Psest_3938 -0.9 -2.8 Uncharacterized protein conserved in bacteria compare
Psest_3494 -0.9 -1.9 hypothetical protein compare
Psest_4134 -0.9 -1.8 Uncharacterized protein conserved in bacteria compare
Psest_1166 -0.9 -1.3 transcriptional regulator, ArgP family compare
Psest_1235 -0.8 -3.2 Leucyl aminopeptidase compare
Psest_0401 -0.8 -0.8 isopentenyl-diphosphate delta-isomerase, type 2 compare
Psest_4010 -0.8 -0.8 peroxiredoxin, OsmC subfamily compare
Psest_1008 -0.8 -0.8 hypothetical protein compare
Psest_1704 -0.8 -0.9 Dehydrogenases (flavoproteins) compare
Psest_2092 -0.8 -2.9 hypothetical protein compare
Psest_1349 -0.8 -2.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_0181 -0.8 -3.5 glycine cleavage system T protein compare
Psest_3306 -0.8 -3.3 conserved hypothetical integral membrane protein compare
Psest_0744 -0.8 -0.7 Uncharacterized conserved protein compare
Psest_3307 -0.8 -4.1 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_3092 -0.8 -1.5 ribonuclease III, bacterial compare
Psest_1994 -0.8 -2.1 Amidases related to nicotinamidase compare
Psest_0740 -0.8 -1.3 Transcriptional regulator compare
Psest_3231 -0.8 -1.3 hypothetical protein compare
Psest_0531 -0.8 -4.2 Phosphate starvation-inducible protein PhoH, predicted ATPase compare
Psest_2327 -0.8 -2.9 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein compare
Psest_0718 -0.8 -2.1 nicotinate-nucleotide pyrophosphorylase compare
Psest_0004 -0.8 -4.6 recF protein compare
Psest_1922 -0.8 -4.2 aminopeptidase N, Escherichia coli type compare
Psest_0719 -0.8 -2.9 Uncharacterized protein conserved in bacteria compare
Psest_1819 -0.7 -6.3 Nucleoside-diphosphate-sugar epimerases compare
Psest_1888 -0.7 -0.7 Sua5/YciO/YrdC/YwlC family protein compare
Psest_1627 -0.7 -4.2 Superfamily II DNA and RNA helicases compare
Psest_3064 -0.7 -1.5 hypothetical protein compare
Psest_2457 -0.7 -2.0 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) compare
Psest_2334 -0.7 -4.9 Uncharacterized protein conserved in bacteria compare
Psest_2017 -0.7 -2.3 Predicted acyltransferase compare
Psest_2225 -0.7 -1.9 Diacylglycerol kinase compare
Psest_0575 -0.7 -0.6 HrpA-like helicases compare
Psest_2906 -0.7 -1.9 tRNA_Thr_CGT compare
Psest_2369 -0.7 -2.6 Transcriptional regulator compare
Psest_2724 -0.7 -1.1 hypothetical protein compare
Psest_1080 -0.7 -4.2 Acetyl/propionyl-CoA carboxylase, alpha subunit compare
Psest_0520 -0.7 -0.6 hypothetical protein compare
Psest_0041 -0.7 -2.4 Uncharacterized protein conserved in bacteria compare
Psest_3042 -0.7 -0.7 Nitrate reductase cytochrome c-type subunit compare
Psest_4310 -0.7 -0.9 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_0919 -0.7 -1.4 Permeases of the drug/metabolite transporter (DMT) superfamily compare
Psest_1386 -0.7 -2.7 Na+/H+-dicarboxylate symporters compare
Psest_1837 -0.7 -2.6 Endoglucanase compare
Psest_0390 -0.7 -2.3 Short-chain dehydrogenases of various substrate specificities compare
Psest_2716 -0.7 -1.9 ABC-type multidrug transport system, ATPase component compare
Psest_2935 -0.7 -1.1 hypothetical protein compare
Psest_3399 -0.7 -0.7 Uncharacterized protein conserved in bacteria compare
Psest_3775 -0.7 -2.3 Mg chelatase-related protein compare
Psest_3944 -0.7 -1.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_3991 -0.7 -1.6 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare


Specific Phenotypes

For 14 genes in this experiment

For nutrient L-Histidine in Pseudomonas stutzeri RCH2

For nutrient L-Histidine across organisms