Experiment set18IT048 for Klebsiella michiganensis M5al

Compare to:

L-Malic acid carbon source and no Nitrogen; normal Wolfe's minerals with nitroloacetic acid; 8 days

200 most important genes:

  gene name fitness t score description  
BWI76_RS08535 -6.6 -2.7 translocation protein TolB compare
BWI76_RS08525 -5.7 -3.2 colicin transporter compare
BWI76_RS17975 -5.5 -4.9 tail-specific protease compare
BWI76_RS17720 -4.5 -1.0 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS21075 -4.4 -1.7 membrane protein compare
BWI76_RS23480 -4.0 -11.7 EAL domain-containing protein compare
BWI76_RS25065 -4.0 -3.9 polyribonucleotide nucleotidyltransferase compare
BWI76_RS06765 -3.6 -3.0 transcriptional regulator compare
BWI76_RS01185 -3.4 -2.9 adenylate cyclase compare
BWI76_RS08530 -3.3 -2.6 protein TolA compare
BWI76_RS00025 -3.2 -1.1 hypothetical protein compare
BWI76_RS25280 -3.2 -1.8 RNase adaptor protein RapZ compare
BWI76_RS26570 -2.9 -2.7 anion permease compare
BWI76_RS02410 -2.8 -2.1 EF-P beta-lysylation protein EpmB compare
BWI76_RS17370 -2.8 -2.1 nitrate transporter NasD compare
BWI76_RS21310 -2.7 -1.2 DNA repair protein RecO compare
BWI76_RS04530 -2.5 -2.6 peptidylprolyl isomerase SurA compare
BWI76_RS23240 -2.5 -3.9 exonuclease V subunit gamma compare
BWI76_RS25060 -2.4 -3.2 lipoprotein NlpI compare
BWI76_RS16965 -2.4 -2.0 murein lipoprotein compare
BWI76_RS00180 -2.3 -1.4 F0F1 ATP synthase subunit epsilon compare
BWI76_RS19840 -2.3 -1.0 hypothetical protein compare
BWI76_RS02530 -2.3 -2.1 tRNA dimethylallyltransferase compare
BWI76_RS06530 -2.2 -6.8 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS05235 -2.1 -1.2 hypothetical protein compare
BWI76_RS17980 -2.0 -2.2 RNA chaperone ProQ compare
BWI76_RS23265 -2.0 -2.7 hypothetical protein compare
BWI76_RS01115 -2.0 -2.0 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS22805 -2.0 -7.1 GTP diphosphokinase compare
BWI76_RS26665 -1.9 -1.9 DNA-binding response regulator compare
BWI76_RS12090 -1.9 -1.7 HNH endonuclease compare
BWI76_RS09640 -1.9 -3.6 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS09660 -1.8 -1.2 DNA translocase FtsK compare
BWI76_RS18715 -1.8 -6.7 hypothetical protein compare
BWI76_RS09635 -1.7 -1.8 amino acid ABC transporter ATP-binding protein compare
BWI76_RS19330 -1.7 -1.0 HAD family hydrolase compare
BWI76_RS06525 -1.7 -2.9 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS08020 -1.7 -4.2 serine-type D-Ala-D-Ala carboxypeptidase compare
BWI76_RS06015 -1.6 -1.3 hypothetical protein compare
BWI76_RS06770 -1.6 -6.0 Hha toxicity attenuator compare
BWI76_RS26390 -1.6 -3.5 cell division protein FtsX compare
BWI76_RS25070 -1.5 -1.4 hypothetical protein compare
BWI76_RS17400 -1.5 -1.0 transporter compare
BWI76_RS26620 -1.5 -1.1 Fe-S biogenesis protein NfuA compare
BWI76_RS20650 -1.5 -1.9 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS02580 -1.5 -1.2 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS11440 -1.4 -1.0 hypothetical protein compare
BWI76_RS04715 -1.4 -1.2 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS03080 -1.4 -2.6 (Fe-S)-cluster assembly protein compare
BWI76_RS04060 -1.4 -1.8 hypothetical protein compare
BWI76_RS02180 -1.4 -0.9 hypothetical protein compare
BWI76_RS21070 -1.4 -1.2 outer membrane protein assembly factor BamB compare
BWI76_RS15835 -1.4 -1.0 hypothetical protein compare
BWI76_RS18710 -1.3 -6.9 GGDEF-domain containing protein compare
BWI76_RS20490 -1.3 -2.0 hypothetical protein compare
BWI76_RS16805 -1.3 -1.3 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS09690 -1.3 -1.2 dimethyl sulfoxide reductase compare
BWI76_RS14155 -1.3 -2.7 transketolase compare
BWI76_RS21370 -1.3 -1.3 ATP-dependent RNA helicase SrmB compare
BWI76_RS14935 -1.3 -1.0 NIPSNAP family containing protein compare
BWI76_RS14735 -1.2 -1.7 type 11 methyltransferase compare
BWI76_RS24025 -1.2 -3.0 agmatinase compare
BWI76_RS16425 -1.2 -1.4 hypothetical protein compare
BWI76_RS00590 -1.2 -1.4 hypothetical protein compare
BWI76_RS25425 -1.2 -1.0 arginine repressor compare
BWI76_RS11780 -1.2 -1.6 2-deoxyglucose-6-phosphatase compare
BWI76_RS12070 -1.2 -0.9 hypothetical protein compare
BWI76_RS25160 -1.2 -1.0 transcription elongation factor GreA compare
BWI76_RS19710 -1.2 -1.6 NupC/NupG family nucleoside CNT transporter compare
BWI76_RS24965 -1.2 -2.2 SCP2 domain-containing protein compare
BWI76_RS20155 -1.1 -1.3 NADH-quinone oxidoreductase subunit I compare
BWI76_RS11515 -1.1 -0.7 peptide-methionine (R)-S-oxide reductase compare
BWI76_RS05205 -1.1 -3.2 type I methionyl aminopeptidase compare
BWI76_RS12980 -1.1 -2.4 AraC family transcriptional regulator compare
BWI76_RS23475 -1.1 -4.5 helix-turn-helix transcriptional regulator compare
BWI76_RS24010 -1.1 -4.1 hypothetical protein compare
BWI76_RS20360 -1.1 -0.6 cell division protein DedD compare
BWI76_RS25220 -1.1 -1.5 outer membrane lipid asymmetry maintenance protein MlaD compare
BWI76_RS08375 -1.1 -1.3 pyroglutamyl-peptidase I compare
BWI76_RS14170 -1.1 -2.2 hypothetical protein compare
BWI76_RS00345 -1.1 -2.1 protein disulfide oxidoreductase DsbA compare
BWI76_RS06230 -1.0 -2.0 DNA-binding response regulator compare
BWI76_RS20380 -1.0 -0.9 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS16895 -1.0 -1.0 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS20390 -1.0 -1.2 erythronate-4-phosphate dehydrogenase compare
BWI76_RS09960 -1.0 -2.3 Lon protease compare
BWI76_RS00760 -1.0 -2.3 cell division protein FtsN compare
BWI76_RS03515 -1.0 -2.4 hypothetical protein compare
BWI76_RS17200 -1.0 -1.0 hypothetical protein compare
BWI76_RS00720 -1.0 -1.4 DNA-binding response regulator compare
BWI76_RS05840 -1.0 -2.3 glutamate 5-kinase compare
BWI76_RS09535 -1.0 -2.3 N-acetylmuramoyl-L-alanine amidase amid compare
BWI76_RS05915 -1.0 -3.1 helix-turn-helix transcriptional regulator compare
BWI76_RS20565 -1.0 -1.4 hypothetical protein compare
BWI76_RS26775 -1.0 -2.4 endo-1,4-D-glucanase compare
BWI76_RS05350 -1.0 -1.7 Rcs stress response system protein RcsF compare
BWI76_RS20640 -1.0 -2.1 cysteine synthase A compare
BWI76_RS18385 -1.0 -0.8 hypothetical protein compare
BWI76_RS08640 -1.0 -1.1 multidrug efflux pump-associated protein, AcrZ family compare
BWI76_RS22700 -1.0 -2.3 sulfate adenylyltransferase subunit 2 compare
BWI76_RS20720 -1.0 -1.0 hypothetical protein compare
BWI76_RS18745 -1.0 -1.1 adenosylhomocysteinase compare
BWI76_RS12895 -1.0 -2.0 hypothetical protein compare
BWI76_RS05200 -1.0 -1.1 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS23015 -1.0 -1.0 cobalt transporter ATP-binding subunit compare
BWI76_RS16505 -1.0 -2.3 MFS transporter compare
BWI76_RS13495 -1.0 -2.2 hypothetical protein compare
BWI76_RS09335 -1.0 -0.9 baseplate assembly protein W compare
BWI76_RS08385 -1.0 -2.1 citrate (Si)-synthase compare
BWI76_RS11235 -1.0 -0.8 hypothetical protein compare
BWI76_RS08520 -1.0 -1.1 colicin transporter TolQ compare
BWI76_RS04705 -1.0 -4.6 DNA-binding transcriptional regulator FruR compare
BWI76_RS18870 -1.0 -0.8 protein NifZ compare
BWI76_RS14320 -1.0 -1.6 hypothetical protein compare
BWI76_RS13730 -1.0 -1.5 hypothetical protein compare
BWI76_RS16210 -1.0 -0.9 hypothetical protein compare
BWI76_RS13180 -1.0 -1.2 multidrug transporter EmrA compare
BWI76_RS02315 -1.0 -4.2 protein-disulfide reductase DsbD compare
BWI76_RS27165 -1.0 -2.3 mannitol-1-phosphate 5-dehydrogenase compare
BWI76_RS24380 -1.0 -2.8 esterase YqiA compare
BWI76_RS02450 -1.0 -3.6 succinate dehydrogenase/fumarate reductase iron-sulfur subunit compare
BWI76_RS22695 -1.0 -2.4 sulfate adenylyltransferase compare
BWI76_RS14390 -0.9 -1.3 hypothetical protein compare
BWI76_RS00400 -0.9 -0.9 glutamine synthetase compare
BWI76_RS20140 -0.9 -2.0 NADH-quinone oxidoreductase subunit L compare
BWI76_RS21345 -0.9 -0.7 sigma-E factor regulatory protein RseB compare
BWI76_RS18580 -0.9 -0.8 hypothetical protein compare
BWI76_RS18050 -0.9 -1.5 hypothetical protein compare
BWI76_RS01545 -0.9 -2.0 thiamine biosynthesis protein ThiS compare
BWI76_RS13955 -0.9 -1.4 hypothetical protein compare
BWI76_RS26015 -0.9 -1.2 DUF2559 domain-containing protein compare
BWI76_RS26670 -0.9 -3.8 two-component sensor histidine kinase compare
BWI76_RS20180 -0.9 -2.6 NADH-quinone oxidoreductase subunit C/D compare
BWI76_RS00335 -0.9 -1.7 hypothetical protein compare
BWI76_RS26405 -0.9 -0.8 16S rRNA (guanine(966)-N(2))-methyltransferase compare
BWI76_RS27620 -0.9 -1.2 hypothetical protein compare
BWI76_RS19470 -0.9 -1.1 DNA-binding response regulator compare
BWI76_RS23230 -0.9 -1.5 exodeoxyribonuclease V subunit beta compare
BWI76_RS07095 -0.9 -1.9 ribosome-associated protein compare
BWI76_RS21350 -0.9 -1.5 anti-RNA polymerase sigma factor SigE compare
BWI76_RS19920 -0.9 -2.7 hybrid sensor histidine kinase/response regulator compare
BWI76_RS15530 -0.9 -1.4 hypothetical protein compare
BWI76_RS01210 -0.9 -1.4 tyrosine recombinase XerC compare
BWI76_RS17300 -0.9 -1.0 tRNA-Tyr compare
BWI76_RS20460 -0.9 -3.1 acetyl-CoA C-acyltransferase FadI compare
BWI76_RS25970 -0.9 -2.1 hypothetical protein compare
BWI76_RS15035 -0.9 -0.9 metal ABC transporter permease compare
BWI76_RS13890 -0.9 -1.5 LysR family transcriptional regulator compare
BWI76_RS07465 -0.9 -1.6 TetR family transcriptional regulator compare
BWI76_RS25910 -0.9 -2.4 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS05810 -0.9 -0.7 hypothetical protein compare
BWI76_RS08210 -0.9 -1.0 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS11230 -0.9 -0.9 NAD-dependent deacylase compare
BWI76_RS12295 -0.9 -2.0 hypothetical protein compare
BWI76_RS15760 -0.9 -0.8 hypothetical protein compare
BWI76_RS10770 -0.8 -1.0 pyrimidine utilization protein C compare
BWI76_RS01630 -0.8 -0.6 16S ribosomal RNA compare
BWI76_RS27605 -0.8 -1.4 hypothetical protein compare
BWI76_RS18755 -0.8 -0.6 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS18430 -0.8 -2.4 hypothetical protein compare
BWI76_RS16120 -0.8 -1.8 4-carboxymuconolactone decarboxylase compare
BWI76_RS05520 -0.8 -1.8 hypothetical protein compare
BWI76_RS26455 -0.8 -0.8 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS20145 -0.8 -0.9 NADH-quinone oxidoreductase subunit K compare
BWI76_RS02445 -0.8 -2.0 fumarate reductase subunit C compare
BWI76_RS01935 -0.8 -1.0 thiamin phosphate synthase compare
BWI76_RS11645 -0.8 -2.4 ABC transporter substrate-binding protein compare
BWI76_RS00100 -0.8 -2.0 hypothetical protein compare
BWI76_RS25195 -0.8 -1.8 maltose metabolism regulator compare
BWI76_RS12225 -0.8 -1.0 hypothetical protein compare
BWI76_RS13185 -0.8 -2.0 MFS transporter compare
BWI76_RS00375 -0.8 -1.4 hypothetical protein compare
BWI76_RS01350 -0.8 -0.5 NAD(P)H-flavin reductase compare
BWI76_RS02725 -0.8 -0.5 HxlR family transcriptional regulator compare
BWI76_RS20355 -0.8 -1.6 colicin V production protein compare
BWI76_RS09970 -0.8 -1.2 porin OmpA compare
BWI76_RS01890 -0.8 -2.1 transcriptional regulator Zur compare
BWI76_RS22090 -0.8 -1.2 transcriptional regulator compare
BWI76_RS17715 -0.8 -2.3 murein transglycosylase compare
BWI76_RS04160 -0.8 -2.9 phosphoserine phosphatase compare
BWI76_RS08805 -0.8 -1.5 gluconeogenesis factor compare
BWI76_RS16920 -0.8 -0.7 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS05790 -0.8 -0.8 phage DNA-binding protein compare
BWI76_RS26760 -0.8 -1.5 C4-dicarboxylate transport protein DctA (from data) compare
BWI76_RS11250 -0.8 -0.8 spermidine/putrescine ABC transporter permease PotB compare
BWI76_RS04465 -0.8 -2.0 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04100 -0.8 -1.9 peptide chain release factor 3 compare
BWI76_RS11370 -0.8 -1.2 iron-dicitrate transporter subunit FecD compare
BWI76_RS27915 -0.8 -1.0 YceK/YidQ family lipoprotein compare
BWI76_RS10035 -0.8 -0.9 hypothetical protein compare
BWI76_RS11835 -0.8 -0.8 putative regulatory protein MarR compare
BWI76_RS10465 -0.8 -1.8 hypothetical protein compare
BWI76_RS00140 -0.7 -0.6 phosphate transport system regulator PhoU compare
BWI76_RS20135 -0.7 -2.1 NADH-quinone oxidoreductase subunit M compare
BWI76_RS02455 -0.7 -3.7 fumarate reductase flavoprotein subunit compare
BWI76_RS20245 -0.7 -1.9 transketolase subunit B compare
BWI76_RS08925 -0.7 -2.5 DNA-binding protein YbiB compare
BWI76_RS20270 -0.7 -2.1 hypothetical protein compare
BWI76_RS15350 -0.7 -0.5 hypothetical protein compare
BWI76_RS00755 -0.7 -1.1 ATP-dependent protease subunit HslV compare


Specific Phenotypes

For 3 genes in this experiment

For nitrogen fixation L-Malic acid in Klebsiella michiganensis M5al

For nitrogen fixation L-Malic acid across organisms