Experiment set17IT036 for Sinorhizobium meliloti 1021

Compare to:

methyl 3-keto-a-D-glucopyranoside carbon source

200 most important genes:

  gene name fitness t score description  
SMc02569 -7.0 -4.8 imidazole glycerol phosphate synthase subunit HisF compare
SMc01494 -6.8 -13.7 phosphoserine phosphatase compare
SMc01726 -6.7 -7.5 acetylglutamate kinase compare
SMc01801 -6.7 -4.4 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc01843 -6.6 -11.1 5,10-methylenetetrahydrofolate reductase compare
SMc02137 -6.4 -4.4 ornithine carbamoyltransferase compare
SMc04045 -6.4 -8.8 dihydroxy-acid dehydratase compare
SMc02899 -6.4 -10.7 prephenate dehydratase compare
SMc00615 -6.4 -12.3 phosphoribosylaminoimidazole synthetase compare
SMc02717 -6.4 -11.5 2-isopropylmalate synthase compare
SMc00614 -6.3 -7.5 phosphoribosylglycinamide formyltransferase compare
SMc01004 -6.3 -9.6 phosphoribosyl-AMP cyclohydrolase compare
SMc02434 -6.2 -4.3 hypothetical protein compare
SMc00640 -6.1 -8.4 phosphoserine aminotransferase compare
SMc04028 -6.1 -15.8 glutamate synthase compare
SMc02572 -5.9 -4.3 imidazole glycerol phosphate synthase subunit HisH compare
SMc00493 -5.9 -5.7 phosphoribosylformylglycinamidine synthase I compare
SMc01431 -5.8 -11.8 acetolactate synthase 3 catalytic subunit compare
SMc03112 -5.8 -18.0 B12-dependent methionine synthase compare
SMc00488 -5.7 -19.4 phosphoribosylformylglycinamidine synthase II compare
SMc03823 -5.7 -12.7 isopropylmalate isomerase large subunit compare
SMc04026 -5.7 -8.2 glutamate synthase compare
SMc02245 -5.6 -3.9 dihydroorotate dehydrogenase 2 compare
SMc03070 -5.6 -5.4 glucose-6-phosphate 1-dehydrogenase compare
SMc02217 -5.6 -7.6 O-succinylhomoserine sulfhydrylase compare
SMc00092 -5.5 -13.4 phosphoadenosine phosphosulfate reductase compare
SMc00993 -5.5 -9.2 phosphoribosylamine--glycine ligase compare
SMc01054 -5.5 -3.7 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc00917 -5.5 -6.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc02123 -5.5 -4.2 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc03895 -5.4 -17.4 pyruvate carboxylase compare
SMc04405 -5.4 -10.7 3-isopropylmalate dehydrogenase compare
SMc03777 -5.3 -7.3 gamma-glutamyl phosphate reductase compare
SMc00495 -5.0 -4.7 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc00554 -4.9 -8.2 amidophosphoribosyltransferase compare
SMc04001 -4.9 -1.9 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc00293 -4.9 -14.4 homoserine dehydrogenase compare
SMc00918 -4.8 -10.8 ATP phosphoribosyltransferase regulatory subunit compare
SMc00090 -4.8 -11.5 sulfate adenylyltransferase compare
SMc03979 -4.7 -3.3 glyceraldehyde-3-phosphate dehydrogenase compare
SMc01881 -4.7 -3.3 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc00711 -4.7 -6.2 cyclohexadienyl dehydrogenase compare
SMc03797 -4.6 -8.9 homoserine O-succinyltransferase compare
SMc02124 -4.6 -13.1 nitrite reductase compare
SMc00494 -4.6 -2.5 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc03161 -4.6 -12.5 oxidoreductase compare
SMc02570 -4.5 -4.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc04002 -4.5 -7.4 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc00131 -4.5 -15.3 transcriptional regulator compare
SMc02766 -4.5 -3.1 tryptophan synthase subunit beta compare
SMc02425 -4.4 -3.3 transcriptional regulator compare
SMc02725 -4.3 -5.9 anthranilate synthase compare
SMc03776 -4.3 -4.1 gamma-glutamyl kinase compare
SMc02767 -4.2 -4.1 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc00091 -4.1 -10.2 sulfate adenylyltransferase compare
SM_b21175 -4.0 -3.9 phosphate uptake ABC transporter permease compare
SMc00017 -4.0 -2.1 homoserine kinase compare
SMc02407 -4.0 -9.2 hypothetical protein compare
SMc00641 -3.9 -6.6 D-3-phosphoglycerate dehydrogenase compare
SMc02307 -3.9 -9.3 histidinol dehydrogenase compare
SM_b21176 -3.8 -4.5 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMa1635 -3.8 -1.5 hypothetical protein compare
SMc00235 -3.8 -2.6 anthranilate phosphoribosyltransferase compare
SMc01770 -3.8 -1.6 serine hydroxymethyltransferase compare
SMc02755 -3.8 -6.3 S-adenosyl-L-homocysteine hydrolase compare
SMc01053 -3.8 -5.1 siroheme synthase compare
SMc03795 -3.7 -1.9 isopropylmalate isomerase small subunit compare
SMc04088 -3.6 -8.3 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc00815 -3.5 -2.3 inosine 5'-monophosphate dehydrogenase compare
SMc01880 -3.3 -2.3 pantoate--beta-alanine ligase compare
SMc02765 -3.3 -7.4 tryptophan synthase subunit alpha compare
SMc00619 -3.3 -2.2 hypothetical protein compare
SMc01360 -3.3 -2.3 aspartate carbamoyltransferase catalytic subunit compare
SMc02166 -3.3 -8.0 dihydroorotase compare
SMc02707 -3.3 -5.0 hypothetical protein compare
SMc02165 -3.2 -4.9 orotate phosphoribosyltransferase compare
SM_b21177 -3.2 -7.7 phosphate uptake ABC transporter ATP-binding protein compare
SMc01028 -3.2 -13.4 phosphopyruvate hydratase compare
SMc00876 -3.1 -6.9 ATP-binding MRP protein compare
SMc00412 -3.1 -3.0 orotidine 5'-phosphate decarboxylase compare
SMc00236 -3.1 -3.0 Indole-3-glycerol phosphate synthase compare
SM_b20329 -3.1 -8.8 required for glucoside 3-dehydrogenase activity on raffinose or trehalose (thuA) (EC 1.1.99.13) (from data) compare
SMc04346 -3.1 -4.0 ketol-acid reductoisomerase compare
SMc03981 -3.0 -4.8 phosphoglycerate kinase compare
SMa1570 -3.0 -2.2 PilA2 pilus assembly protein compare
SM_b20325 -3.0 -7.3 ABC transporter for D-trehalose/D-maltose/sucrose, substrate-binding component (ThuE) (from data) conserved
SMc02138 -3.0 -5.4 acetylornithine transaminase compare
SMc03974 -3.0 -4.3 hypothetical protein compare
SMc02246 -2.9 -1.1 hypothetical protein compare
SMc02858 -2.9 -1.1 chaperone protein DnaJ compare
SMc01361 -2.9 -2.8 dihydroorotase compare
SMc00294 -2.8 -9.4 aminotransferase compare
SMc01124 -2.8 -8.2 PII uridylyl-transferase compare
SMc00726 -2.8 -1.0 thiol:disulfide interchange redox-active center transmembrane protein compare
SM_b20326 -2.7 -5.3 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 1 (ThuF) (from data) conserved
SM_b20994 -2.6 -4.9 hypothetical protein compare
SMc02172 -2.6 -10.5 transcriptional regulator compare
SMc03826 -2.6 -1.8 argininosuccinate synthase compare
SM_b20953 -2.4 -1.6 hypothetical protein compare
SM_b21174 -2.4 -3.2 phosphate uptake ABC transporter permease compare
SMc03062 -2.4 -7.6 ABC transporter for D-maltose/D-trehalose/sucrose, permease component 1 (AglF) (from data) compare
SMc03978 -2.3 -1.6 transketolase compare
SMc03162 -2.3 -8.9 3-ketoglucose dehydratase (from data) compare
SMc02838 -2.3 -5.7 phosphoglyceromutase compare
SMa2020 -2.2 -5.6 Transcriptional regulator compare
SMc02983 -2.2 -6.2 ornithine, DAP, or arginine decarboxylase compare
SMc01578 -2.1 -9.7 aspartate aminotransferase compare
SMc00451 -2.1 -8.7 processing protease compare
SMc02478 -2.0 -7.9 hypothetical protein compare
SMa0087 -2.0 -1.9 hypothetical protein compare
SMc03065 -2.0 -9.1 ABC transporter for D-maltose/D-trehalose/sucrose, ATPase component (AglK) (from data) compare
SMc01430 -2.0 -3.3 acetolactate synthase 3 regulatory subunit compare
SMc02835 -1.9 -6.1 glucokinase compare
SMc01207 -1.9 -2.2 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc00982 -1.9 -5.5 dioxygenase compare
SMa1365 -1.9 -1.1 ATP-binding protein compare
SMc00405 -1.9 -7.2 hypothetical protein compare
SMc03763 -1.9 -1.3 cytosine-specific methyltransferase compare
SM_b20327 -1.8 -3.0 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 2 (ThuG) (from data) compare
SMa5010 -1.8 -1.3 hypothetical protein compare
SMc01164 -1.8 -7.1 hypothetical protein compare
SMc01568 -1.8 -1.8 hypothetical protein compare
SMc02640 -1.7 -3.3 UDP-glucuronic acid epimerase compare
SMc03140 -1.7 -4.4 transcriptional regulator compare
SMc03061 -1.7 -9.8 ABC transporter for D-maltose/D-trehalose/sucrose, substrate-binding component (AglE) (from data) compare
SMa5033 -1.7 -1.2 hypothetical protein compare
SMc02485 -1.6 -1.9 signal peptide protein compare
SMa0789 -1.6 -2.7 GntR family transcriptional regulator compare
SMc03069 -1.6 -1.8 6-phosphogluconolactonase compare
SMc01991 -1.6 -2.0 short chain dehydrogenase compare
SMc04005 -1.6 -5.5 pyruvate kinase compare
SM_b20258 -1.6 -2.4 transcriptional regulator compare
SM_b20312 -1.5 -6.7 dihydroxyacetone kinase compare
SMc00419 -1.5 -3.2 glutathione synthetase compare
SMc03153 -1.5 -2.7 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase compare
SMc03063 -1.5 -9.1 ABC transporter for D-maltose/D-trehalose/sucrose, permease component 2 (AglG) (from data) compare
SMc04262 -1.5 -7.9 6-phosphogluconate dehydrogenase compare
SMc01569 -1.5 -0.7 carbamoyl phosphate synthase small subunit compare
SM_b20026 -1.5 -2.1 hypothetical protein compare
SM_b21132 -1.4 -2.4 sulfate ABC transporter permease compare
SMc00414 -1.4 -7.5 hypothetical protein compare
SMc02225 -1.4 -4.3 hypothetical protein compare
SMc00647 -1.4 -2.8 ribosomal large subunit pseudouridine synthase compare
SMc02435 -1.4 -1.5 methyltransferase compare
SMa1442 -1.3 -3.8 GntR family transcriptional regulator compare
SMc04327 -1.3 -1.3 hypothetical protein compare
SMc03100 -1.3 -1.4 hypothetical protein compare
SMc01215 -1.3 -0.9 carbamoyl phosphate synthase large subunit compare
SM_b21182 -1.3 -4.3 hypothetical protein compare
SMc02558 -1.3 -3.5 hypothetical protein compare
SMc01522 -1.3 -1.9 hypothetical protein compare
SMc01206 -1.2 -1.6 queuine tRNA-ribosyltransferase compare
SM_b20474 -1.2 -2.1 hypothetical protein compare
SM_b20519 -1.2 -2.4 hypothetical protein compare
SM_b21133 -1.2 -5.5 sulfate ABC transporter substrate-binding protein compare
SMc04003 -1.2 -1.2 50S ribosomal protein L36 compare
SM_b21181 -1.2 -4.2 glutaryl-CoA dehydrogenase compare
SMc03013 -1.2 -2.8 hypothetical protein compare
SMc03068 -1.2 -5.2 phosphogluconate dehydratase compare
SMc00450 -1.1 -1.6 protoheme IX farnesyltransferase compare
SMc00555 -1.1 -1.2 colicin V production transmembrane protein compare
SMc01842 -1.1 -1.2 methyltransferase transcription regulator protein compare
SMc03229 -1.1 -1.2 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc00349 -1.1 -5.5 GTP-binding protein LepA compare
SM_b21130 -1.1 -5.6 sulfate ABC transporter ATP-binding protein compare
SMc04134 -1.1 -3.1 transcriptional regulator compare
SMc03924 -1.1 -5.9 glycogen synthase compare
SMc02112 -1.1 -3.8 hypothetical protein compare
SMc00012 -1.1 -1.2 cytochrome C oxidase assembly protein compare
SMc00854 -1.1 -1.3 hypothetical protein compare
SM_b20717 -1.1 -4.4 LacI family transcriptional regulator compare
SMc02521 -1.1 -2.2 glycerol-3-phosphate regulon repressor transcription regulator protein compare
SMc04000 -1.1 -0.8 hypothetical protein compare
SMc04085 -1.1 -3.5 hypothetical protein compare
SM_b20509 -1.1 -1.8 transcriptional regulator compare
SMc03849 -1.1 -0.6 heme exporter C (cytochrome C-type biogenesis protein) transmembrane compare
SMc02234 -1.1 -1.3 hypothetical protein compare
SMa1240 -1.0 -1.0 NapF ferredoxin component of periplasmic nitrate reductase compare
SMc01143 -1.0 -3.9 heat-inducible transcription repressor compare
SMc00321 -1.0 -3.9 tRNA pseudouridine synthase B compare
SMc02048 -1.0 -5.3 glycine cleavage system protein H compare
SM_b20086 -1.0 -1.3 hypothetical protein compare
SMc00286 -1.0 -1.7 hemolysin-type calcium-binding protein compare
SM_b21131 -1.0 -4.0 sulfate ABC transporter permease compare
SMc02861 -1.0 -1.4 phosphate transporter compare
SMa0450 -1.0 -1.4 hypothetical protein compare
SMc02164 -1.0 -1.9 fructokinase compare
SMc00877 -1.0 -5.6 transcriptional regulator compare
SMa1053 -1.0 -1.5 hypothetical protein compare
SMc04348 -1.0 -1.1 transcriptional regulator compare
SMc02470 -1.0 -2.7 transcriptional regulator compare
SMc04453 -1.0 -1.1 hypothetical protein compare
SMa0222 -1.0 -1.7 GntR family transcriptional regulator compare
SM_b20501 -1.0 -5.0 transcriptional regulator compare
SMc02084 -1.0 -0.8 biopolymer transport transmembrane protein compare
SM_b20540 -1.0 -1.0 hypothetical protein compare
SM_b20413 -1.0 -0.9 hypothetical protein compare
SMc00511 -1.0 -3.5 D-ribulose-5-phosphate 3-epimerase compare
SMc00302 -0.9 -1.4 hypothetical protein compare
SM_b21253 -0.9 -3.3 hypothetical protein compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source methyl 3-keto-a-D-glucopyranoside in Sinorhizobium meliloti 1021

For carbon source methyl 3-keto-a-D-glucopyranoside across organisms