Experiment set17IT023 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_1percent_glucose with Sodium Chloride 600 mM and Betaine 100 uM

200 most important genes:

  gene name fitness t score description  
BWI76_RS21475 -7.4 -7.2 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS18950 -6.7 -5.8 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00805 -6.7 -6.3 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS20965 -6.6 -4.1 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS23360 -6.2 -4.3 diaminopimelate decarboxylase compare
BWI76_RS04670 -5.6 -7.5 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04255 -5.5 -10.5 threonine synthase compare
BWI76_RS18930 -5.4 -4.0 histidinol-phosphate transaminase compare
BWI76_RS18920 -5.2 -4.4 ATP phosphoribosyltransferase compare
BWI76_RS18940 -5.2 -6.8 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS05840 -5.1 -8.1 glutamate 5-kinase compare
BWI76_RS04305 -5.1 -1.9 molecular chaperone DnaJ compare
BWI76_RS00990 -5.0 -12.6 ketol-acid reductoisomerase compare
BWI76_RS23220 -5.0 -7.9 amino-acid N-acetyltransferase compare
BWI76_RS00845 -4.9 -8.9 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS20350 -4.9 -5.4 amidophosphoribosyltransferase compare
BWI76_RS04645 -4.8 -6.7 3-dehydroquinase compare
BWI76_RS04160 -4.8 -4.3 phosphoserine phosphatase compare
BWI76_RS01655 -4.8 -9.5 homoserine O-succinyltransferase compare
BWI76_RS11840 -4.8 -6.4 tryptophan synthase subunit alpha compare
BWI76_RS07065 -4.8 -7.7 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS25115 -4.7 -7.9 argininosuccinate synthase compare
BWI76_RS00965 -4.7 -1.8 acetolactate synthase 2 small subunit compare
BWI76_RS23920 -4.7 -8.2 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS03010 -4.7 -7.6 ornithine carbamoyltransferase compare
BWI76_RS00855 -4.6 -7.5 argininosuccinate lyase compare
BWI76_RS00785 -4.6 -7.8 cystathionine gamma-synthase compare
BWI76_RS07070 -4.6 -4.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS26085 -4.6 -2.9 3-dehydroquinate synthase compare
BWI76_RS04675 -4.6 -7.1 3-isopropylmalate dehydrogenase compare
BWI76_RS00850 -4.5 -10.9 acetylglutamate kinase compare
BWI76_RS02735 -4.5 -6.9 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS00980 -4.5 -11.7 PLP-dependent threonine dehydratase compare
BWI76_RS11860 -4.5 -8.1 anthranilate synthase component I compare
BWI76_RS09760 -4.5 -4.8 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS21265 -4.5 -12.2 phosphoribosylformylglycinamidine synthase compare
BWI76_RS04665 -4.4 -20.2 3-isopropylmalate dehydratase small subunit compare
BWI76_RS02995 -4.4 -6.8 aspartate carbamoyltransferase compare
BWI76_RS18925 -4.4 -7.4 histidinol dehydrogenase compare
BWI76_RS05835 -4.4 -3.7 gamma-glutamyl-phosphate reductase compare
BWI76_RS20895 -4.4 -5.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04465 -4.3 -5.1 carbamoyl-phosphate synthase small subunit compare
BWI76_RS23365 -4.3 -9.9 LysR family transcriptional regulator compare
BWI76_RS09755 -4.2 -9.0 phosphoserine transaminase compare
BWI76_RS01610 -4.2 -5.0 phosphoribosylamine--glycine ligase compare
BWI76_RS09640 -4.2 -2.9 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS08530 -4.2 -2.1 protein TolA compare
BWI76_RS00835 -4.1 -13.3 phosphoenolpyruvate carboxylase compare
BWI76_RS24285 -4.1 -9.5 cystathionine beta-lyase compare
BWI76_RS01615 -4.1 -7.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS11845 -4.0 -2.9 tryptophan synthase subunit beta compare
BWI76_RS18935 -4.0 -6.0 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS21465 -4.0 -4.9 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS10990 -4.0 -2.3 dihydroorotase compare
BWI76_RS09645 -3.9 -1.5 thioredoxin-disulfide reductase compare
BWI76_RS25645 -3.8 -9.5 shikimate dehydrogenase compare
BWI76_RS18955 -3.8 -6.4 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS04245 -3.7 -16.9 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04250 -3.7 -9.8 homoserine kinase compare
BWI76_RS11965 -3.7 -3.1 orotidine-5'-phosphate decarboxylase compare
BWI76_RS00975 -3.6 -8.5 dihydroxy-acid dehydratase compare
BWI76_RS11850 -3.6 -9.3 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS11855 -3.6 -8.4 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS27385 -3.6 -7.6 orotate phosphoribosyltransferase compare
BWI76_RS02250 -3.5 -11.9 proline/betaine transporter conserved
BWI76_RS25315 -3.5 -9.5 glutamate synthase large subunit compare
BWI76_RS04470 -3.5 -8.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS25320 -3.4 -8.0 glutamate synthase compare
BWI76_RS05015 -3.3 -3.3 transcriptional regulator compare
BWI76_RS04685 -3.2 -9.6 putative leucine operon leader peptide compare
BWI76_RS09910 -3.2 -13.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS27430 -3.2 -1.7 (p)ppGpp synthetase compare
BWI76_RS04680 -3.2 -8.7 2-isopropylmalate synthase compare
BWI76_RS22765 -3.2 -12.6 sulfite reductase subunit alpha compare
BWI76_RS15825 -3.1 -2.6 hypothetical protein compare
BWI76_RS25335 -3.1 -4.1 stringent starvation protein A compare
BWI76_RS08385 -3.1 -3.9 citrate (Si)-synthase compare
BWI76_RS01800 -3.0 -5.4 glucose-6-phosphate isomerase compare
BWI76_RS09635 -3.0 -2.0 amino acid ABC transporter ATP-binding protein compare
BWI76_RS20435 -2.9 -1.5 chorismate synthase compare
BWI76_RS22760 -2.8 -7.1 sulfite reductase subunit beta compare
BWI76_RS22690 -2.8 -4.7 adenylyl-sulfate kinase compare
BWI76_RS20355 -2.7 -2.6 colicin V production protein compare
BWI76_RS20640 -2.7 -4.3 cysteine synthase A compare
BWI76_RS08535 -2.6 -1.8 translocation protein TolB compare
BWI76_RS26000 -2.5 -7.1 aspartate aminotransferase family protein compare
BWI76_RS22755 -2.5 -5.4 phosphoadenosine phosphosulfate reductase compare
BWI76_RS09190 -2.4 -2.8 hypothetical protein compare
BWI76_RS17720 -2.4 -1.3 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS00985 -2.4 -8.1 transcriptional regulator IlvY compare
BWI76_RS26395 -2.3 -4.0 cell division protein FtsE compare
BWI76_RS24900 -2.3 -3.4 DeoR family transcriptional regulator compare
BWI76_RS26055 -2.2 -7.2 siroheme synthase compare
BWI76_RS01275 -2.2 -6.0 LysR family transcriptional regulator compare
BWI76_RS24175 -2.2 -8.4 ornithine decarboxylase compare
BWI76_RS22695 -2.1 -4.9 sulfate adenylyltransferase compare
BWI76_RS22700 -2.0 -7.3 sulfate adenylyltransferase subunit 2 compare
BWI76_RS04240 -2.0 -3.7 thr operon leader peptide compare
BWI76_RS27390 -2.0 -3.5 ribonuclease PH compare
BWI76_RS15360 -1.9 -3.1 hypothetical protein compare
BWI76_RS01325 -1.8 -2.8 twin-arginine translocase subunit TatB compare
BWI76_RS23265 -1.8 -3.4 hypothetical protein compare
BWI76_RS07740 -1.8 -2.2 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS04315 -1.8 -7.4 Na+/H+ antiporter NhaA compare
BWI76_RS03660 -1.8 -3.7 hypothetical protein compare
BWI76_RS01200 -1.7 -2.0 diaminopimelate epimerase compare
BWI76_RS08520 -1.7 -1.5 colicin transporter TolQ compare
BWI76_RS17980 -1.6 -4.6 RNA chaperone ProQ compare
BWI76_RS04510 -1.6 -1.6 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS15840 -1.6 -3.5 prophage protein compare
BWI76_RS08525 -1.6 -2.3 colicin transporter compare
BWI76_RS22805 -1.5 -6.7 GTP diphosphokinase compare
BWI76_RS00400 -1.5 -0.9 glutamine synthetase compare
BWI76_RS09655 -1.5 -4.7 leucine-responsive regulatory protein compare
BWI76_RS15660 -1.5 -1.3 hypothetical protein compare
BWI76_RS18580 -1.4 -2.2 hypothetical protein compare
BWI76_RS15830 -1.4 -2.5 hypothetical protein compare
BWI76_RS20995 -1.4 -1.1 RNA degradosome polyphosphate kinase compare
BWI76_RS16240 -1.4 -2.0 anti-adapter protein IraM compare
BWI76_RS20440 -1.4 -1.6 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS10465 -1.4 -2.5 hypothetical protein compare
BWI76_RS00355 -1.4 -2.9 DNA polymerase I compare
BWI76_RS21980 -1.4 -2.5 hypothetical protein compare
BWI76_RS05005 -1.3 -2.9 polynucleotide adenylyltransferase compare
BWI76_RS05555 -1.3 -2.0 Crl family RNA polymerase assembly factor compare
BWI76_RS09195 -1.3 -1.8 N-acetyltransferase compare
BWI76_RS22645 -1.3 -3.7 RNA polymerase sigma factor RpoS compare
BWI76_RS26410 -1.3 -1.9 membrane protein compare
BWI76_RS25920 -1.3 -1.3 peptidylprolyl isomerase compare
BWI76_RS22485 -1.3 -2.5 hypothetical protein compare
BWI76_RS01330 -1.2 -2.8 twin-arginine translocase subunit TatC compare
BWI76_RS18190 -1.2 -2.7 carboxy-S-adenosyl-L-methionine synthase CmoA compare
BWI76_RS27235 -1.2 -6.3 murein hydrolase activator EnvC compare
BWI76_RS21580 -1.2 -1.5 SsrA-binding protein compare
BWI76_RS18125 -1.2 -1.7 murein DD-endopeptidase MepM compare
BWI76_RS26620 -1.2 -1.1 Fe-S biogenesis protein NfuA compare
BWI76_RS13755 -1.2 -1.6 hypothetical protein compare
BWI76_RS22705 -1.2 -5.6 siroheme synthase compare
BWI76_RS11430 -1.2 -1.2 lipoprotein compare
BWI76_RS01110 -1.2 -2.3 TDP-fucosamine acetyltransferase compare
BWI76_RS23240 -1.2 -0.8 exonuclease V subunit gamma compare
BWI76_RS00960 -1.2 -4.3 acetolactate synthase 2 catalytic subunit compare
BWI76_RS15620 -1.2 -1.9 hypothetical protein compare
BWI76_RS27440 -1.1 -3.4 DNA helicase RecG compare
BWI76_RS00180 -1.1 -1.4 F0F1 ATP synthase subunit epsilon compare
BWI76_RS12040 -1.1 -1.3 hypothetical protein compare
BWI76_RS14915 -1.1 -1.3 hypothetical protein compare
BWI76_RS26075 -1.1 -1.7 DNA adenine methylase compare
BWI76_RS08110 -1.1 -2.4 glutamate/aspartate ABC transporter substrate-binding protein compare
BWI76_RS16370 -1.0 -3.1 electron transport complex subunit D compare
BWI76_RS21480 -1.0 -2.6 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS18455 -1.0 -1.2 tRNA-Ser compare
BWI76_RS06525 -1.0 -4.8 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS17785 -1.0 -3.7 septum site-determining protein MinD compare
BWI76_RS14410 -1.0 -1.7 hypothetical protein compare
BWI76_RS01585 -1.0 -2.4 transcriptional regulator compare
BWI76_RS12090 -1.0 -1.3 HNH endonuclease compare
BWI76_RS25280 -1.0 -1.7 RNase adaptor protein RapZ compare
BWI76_RS17110 -1.0 -1.7 vitamin B12 ABC transporter permease BtuC compare
BWI76_RS13595 -1.0 -4.5 transcriptional regulator compare
BWI76_RS11820 -1.0 -1.2 short-chain dehydrogenase/reductase SDR compare
BWI76_RS12335 -1.0 -2.6 hypothetical protein compare
BWI76_RS16190 -1.0 -2.3 universal stress protein UspE compare
BWI76_RS08020 -0.9 -4.6 serine-type D-Ala-D-Ala carboxypeptidase compare
BWI76_RS01545 -0.9 -2.5 thiamine biosynthesis protein ThiS compare
BWI76_RS01630 -0.9 -1.0 16S ribosomal RNA compare
BWI76_RS24080 -0.9 -1.7 DUF179 domain-containing protein compare
BWI76_RS20155 -0.9 -2.0 NADH-quinone oxidoreductase subunit I compare
BWI76_RS01220 -0.9 -4.5 DNA-dependent helicase II compare
BWI76_RS20380 -0.9 -0.8 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS15835 -0.9 -0.8 hypothetical protein compare
BWI76_RS07730 -0.9 -1.3 iron-enterobactin transporter membrane protein compare
BWI76_RS21810 -0.9 -1.3 universal stress protein compare
BWI76_RS00380 -0.9 -4.4 oxygen-independent coproporphyrinogen III oxidase compare
BWI76_RS26390 -0.9 -2.1 cell division protein FtsX compare
BWI76_RS08705 -0.9 -2.6 putative LuxR family regulatory protein compare
BWI76_RS15850 -0.9 -0.7 DUF1317 domain-containing protein compare
BWI76_RS19690 -0.9 -2.1 LysR family transcriptional regulator compare
BWI76_RS14075 -0.9 -0.9 TetR family transcriptional regulator compare
BWI76_RS23140 -0.9 -1.8 carboxysome shell protein compare
BWI76_RS07645 -0.9 -1.3 short-chain dehydrogenase/reductase compare
BWI76_RS09470 -0.8 -2.4 putrescine ABC transporter permease compare
BWI76_RS18235 -0.8 -3.5 trehalose-phosphatase compare
BWI76_RS09315 -0.8 -1.0 hypothetical protein compare
BWI76_RS08260 -0.8 -2.3 LysR family transcriptional regulator compare
BWI76_RS06475 -0.8 -1.4 protoheme IX farnesyltransferase compare
BWI76_RS20700 -0.8 -4.6 sulfate/thiosulfate transporter subunit compare
BWI76_RS17300 -0.8 -0.8 tRNA-Tyr compare
BWI76_RS18905 -0.8 -2.3 putrescine/spermidine ABC transporter compare
BWI76_RS04060 -0.8 -1.7 hypothetical protein compare
BWI76_RS24740 -0.8 -2.1 GntR family transcriptional regulator compare
BWI76_RS20705 -0.8 -4.1 thiosulfate transporter subunit compare
BWI76_RS15195 -0.8 -1.3 DUF4186 domain-containing protein compare
BWI76_RS00575 -0.8 -5.0 DNA-binding protein compare
BWI76_RS12535 -0.8 -2.2 hypothetical protein compare
BWI76_RS20065 -0.8 -3.3 1,4-dihydroxy-2-naphthoyl-CoA synthase compare
BWI76_RS11700 -0.8 -0.7 hypothetical protein compare
BWI76_RS07820 -0.8 -1.0 S-methyl-5-thioribose kinase compare
BWI76_RS18335 -0.8 -3.1 DNA-binding response regulator compare
BWI76_RS23915 -0.8 -1.5 5-formyltetrahydrofolate cyclo-ligase compare


Specific Phenotypes

For 3 genes in this experiment

For stress Sodium Chloride in Klebsiella michiganensis M5al

For stress Sodium Chloride across organisms