Experiment set17IT023 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_1percent_glucose with Sodium Chloride 600 mM and Betaine 100 uM

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS01185 +1.7 4.3 adenylate cyclase compare
BWI76_RS20750 +1.5 2.5 carboxysome structural protein EutK compare
BWI76_RS21460 +1.3 2.3 translation inhibitor protein RaiA compare
BWI76_RS12465 +1.3 2.1 phage shock protein D compare
BWI76_RS14835 +1.2 2.2 hypothetical protein compare
BWI76_RS09970 +1.1 1.4 porin OmpA compare
BWI76_RS00140 +1.1 1.1 phosphate transport system regulator PhoU compare
BWI76_RS00710 +1.1 2.6 6-N-hydroxylaminopurine resistance protein compare
BWI76_RS07790 +1.0 3.0 plasmid stabilization protein compare
BWI76_RS11410 +1.0 2.7 leucine efflux protein compare
BWI76_RS11435 +1.0 1.2 hypothetical protein compare
BWI76_RS06190 +1.0 2.7 hypothetical protein compare
BWI76_RS17805 +0.9 1.7 membrane protein compare
BWI76_RS20230 +0.9 1.8 hypothetical protein compare
BWI76_RS17565 +0.9 1.6 hypothetical protein compare
BWI76_RS20375 +0.9 2.2 membrane protein compare
BWI76_RS17945 +0.8 2.0 hypothetical protein compare
BWI76_RS17045 +0.8 1.5 hypothetical protein compare
BWI76_RS02815 +0.8 2.1 fructose-bisphosphatase class I compare
BWI76_RS12185 +0.8 1.3 hypothetical protein compare
BWI76_RS11150 +0.8 2.0 membrane protein compare
BWI76_RS21675 +0.8 1.9 hypothetical protein compare
BWI76_RS12870 +0.8 1.3 putative phytanoyl-CoA dioxygenase compare
BWI76_RS16150 +0.8 2.6 IclR family transcriptional regulator compare
BWI76_RS19865 +0.8 2.2 ecotin compare
BWI76_RS11035 +0.8 2.9 putative LysR-family transcriptional regulator compare
BWI76_RS19985 +0.8 1.6 MFS transporter compare
BWI76_RS24880 +0.7 2.0 PTS galactitol transporter subunit IIA compare
BWI76_RS00715 +0.7 2.4 two-component sensor histidine kinase compare
BWI76_RS24240 +0.7 1.7 hypothetical protein compare
BWI76_RS20930 +0.7 1.4 arsenate reductase (glutaredoxin) compare
BWI76_RS26630 +0.7 2.2 pimeloyl-[acyl-carrier protein] methyl ester esterase compare
BWI76_RS09305 +0.7 1.6 hypothetical protein compare
BWI76_RS08495 +0.7 3.3 cytochrome bd-I ubiquinol oxidase subunit I compare
BWI76_RS14770 +0.7 1.2 PTS IIA 2 domain protein compare
BWI76_RS03105 +0.7 1.2 myo-inosose-2 dehydratase compare
BWI76_RS11865 +0.7 2.3 phosphatase compare
BWI76_RS04525 +0.7 1.2 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS15190 +0.7 2.3 GGDEF domain-containing protein compare
BWI76_RS14975 +0.7 2.1 glyoxalase-like domain protein compare
BWI76_RS22090 +0.7 2.1 transcriptional regulator compare
BWI76_RS08390 +0.7 2.2 hypothetical protein compare
BWI76_RS16935 +0.7 1.3 shikimate dehydrogenase compare
BWI76_RS05075 +0.7 1.0 type II secretion system protein GspG compare
BWI76_RS16645 +0.7 2.5 DeoR family transcriptional regulator compare
BWI76_RS16570 +0.7 3.1 catalase compare
BWI76_RS11255 +0.7 1.2 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS21445 +0.7 1.6 hypothetical protein compare
BWI76_RS10430 +0.7 2.9 thiol:disulfide interchange protein DsbG compare
BWI76_RS13945 +0.6 1.4 lysine exporter protein LysE/YggA compare
BWI76_RS19465 +0.6 1.7 hypothetical protein compare
BWI76_RS06735 +0.6 1.6 50S ribosomal protein L31 compare
BWI76_RS12790 +0.6 0.8 lactate dehydrogenase compare
BWI76_RS08405 +0.6 1.7 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS15845 +0.6 0.7 hypothetical protein compare
BWI76_RS23320 +0.6 1.3 hypothetical protein compare
BWI76_RS21285 +0.6 1.5 HAD family hydrolase compare
BWI76_RS10730 +0.6 2.2 bifunctional glucose-1-phosphatase/inositol phosphatase compare
BWI76_RS02090 +0.6 1.2 membrane protein compare
BWI76_RS11525 +0.6 1.0 HNH endonuclease compare
BWI76_RS15200 +0.6 2.1 glutaminase compare
BWI76_RS05050 +0.6 2.3 general secretion pathway protein GspL compare
BWI76_RS21450 +0.6 1.3 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS17615 +0.6 1.7 RNA pseudouridine synthase compare
BWI76_RS26045 +0.6 1.3 nitrite reductase small subunit compare
BWI76_RS24485 +0.6 1.5 bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase compare
BWI76_RS21945 +0.6 1.8 LysR family transcriptional regulator compare
BWI76_RS16390 +0.6 3.2 dipeptide/tripeptide permease A compare
BWI76_RS08735 +0.6 3.0 Urocanate hydratase (EC 4.2.1.49) (from data) compare
BWI76_RS05985 +0.6 2.5 branched-chain amino acid ABC transporter permease compare
BWI76_RS18815 +0.6 2.0 nitrogenase molybdenum-iron protein alpha chain compare
BWI76_RS20785 +0.6 0.8 ethanolamine utilization protein EutJ compare
BWI76_RS09830 +0.6 1.5 tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM compare
BWI76_RS23895 +0.6 0.6 Xaa-Pro aminopeptidase compare
BWI76_RS08820 +0.6 1.5 molybdenum cofactor biosynthesis protein compare
BWI76_RS13175 +0.6 2.0 NodT family RND efflux system outer membrane lipoprotein compare
BWI76_RS20285 +0.6 2.9 glutathione S-transferase compare
BWI76_RS17645 +0.6 1.9 hypothetical protein compare
BWI76_RS27735 +0.6 1.5 hypothetical protein compare
BWI76_RS17100 +0.6 1.7 glutathione peroxidase compare
BWI76_RS15330 +0.6 2.3 urea ABC transporter permease subunit UrtC compare
BWI76_RS05355 +0.6 2.1 methionine ABC transporter substrate-binding protein MetQ compare
BWI76_RS14625 +0.6 0.9 protein TolA compare
BWI76_RS22365 +0.6 3.5 hydrogenase expression/formation protein HypE compare
BWI76_RS16330 +0.6 1.9 oxidoreductase compare
BWI76_RS00370 +0.6 1.5 GTPase-activating protein compare
BWI76_RS07805 +0.6 2.0 sugar ABC transporter permease compare
BWI76_RS22380 +0.6 2.4 6-phospho-beta-glucosidase compare
BWI76_RS09290 +0.6 1.8 phage Tail Protein X compare
BWI76_RS13095 +0.5 1.2 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS08585 +0.5 1.4 nicotinamide riboside transporter PnuC compare
BWI76_RS22200 +0.5 1.8 iron ABC transporter compare
BWI76_RS11520 +0.5 0.9 hypothetical protein compare
BWI76_RS23880 +0.5 1.7 Aminomethyltransferase (EC 2.1.2.10) (from data) compare
BWI76_RS19995 +0.5 2.2 IclR family transcriptional regulator compare
BWI76_RS13215 +0.5 0.9 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS12865 +0.5 1.6 acetylornithine deacetylase compare
BWI76_RS21325 +0.5 1.4 hypothetical protein compare
BWI76_RS21940 +0.5 1.5 SDR family oxidoreductase compare
BWI76_RS11750 +0.5 2.5 chitooligosaccharide deacetylase compare
BWI76_RS10575 +0.5 0.7 polar amino acid ABC transporter permease compare
BWI76_RS06800 +0.5 0.9 DUF2496 domain-containing protein compare
BWI76_RS14815 +0.5 2.7 MdaB protein compare
BWI76_RS22515 +0.5 2.8 acyl dehydratase compare
BWI76_RS10040 +0.5 1.3 heat-shock protein HspQ compare
BWI76_RS26140 +0.5 1.3 GMP/IMP nucleotidase compare
BWI76_RS15060 +0.5 1.3 MarR family transcriptional regulator compare
BWI76_RS07500 +0.5 1.7 RND transporter MFP subunit compare
BWI76_RS16260 +0.5 1.2 two-component sensor histidine kinase compare
BWI76_RS25630 +0.5 1.7 hypothetical protein compare
BWI76_RS05045 +0.5 1.6 general secretion pathway protein GspM compare
BWI76_RS19975 +0.5 1.9 sn-glycerol-3-phosphate dehydrogenase subunit C compare
BWI76_RS17280 +0.5 2.2 patatin family protein compare
BWI76_RS23055 +0.5 2.4 cobalamin biosynthesis protein CbiG compare
BWI76_RS14040 +0.5 1.3 thiaminase compare
BWI76_RS25435 +0.5 1.9 membrane protein compare
BWI76_RS26440 +0.5 0.9 hypothetical protein compare
BWI76_RS27605 +0.5 1.5 hypothetical protein compare
BWI76_RS01905 +0.5 0.8 envelope stress response protein PspG compare
BWI76_RS27050 +0.5 3.0 hypothetical protein compare
BWI76_RS25850 +0.5 1.7 prepilin peptidase compare
BWI76_RS17835 +0.5 2.6 sugar ABC transporter permease compare
BWI76_RS06510 +0.5 1.7 BolA family transcriptional regulator compare
BWI76_RS06335 +0.5 0.9 nucleoside-specific channel-forming protein Tsx compare
BWI76_RS01195 +0.5 1.2 membrane protein compare
BWI76_RS09110 +0.5 2.2 glutathione ABC transporter permease GsiD compare
BWI76_RS13805 +0.5 1.8 inorganic diphosphatase compare
BWI76_RS07470 +0.5 1.8 MBL fold metallo-hydrolase compare
BWI76_RS26270 +0.5 1.8 N-acetyltransferase compare
BWI76_RS08500 +0.5 1.0 cytochrome d ubiquinol oxidase subunit 2 compare
BWI76_RS24150 +0.5 2.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB compare
BWI76_RS13170 +0.5 1.5 methyltransferase compare
BWI76_RS19870 +0.5 1.5 malate:quinone oxidoreductase compare
BWI76_RS24920 +0.5 1.8 YraN family protein compare
BWI76_RS23325 +0.5 1.3 hypothetical protein compare
BWI76_RS07855 +0.5 1.0 PucR family transcriptional regulator compare
BWI76_RS08980 +0.5 0.8 DNA starvation/stationary phase protection protein compare
BWI76_RS10400 +0.5 1.0 hypothetical protein compare
BWI76_RS13975 +0.5 1.5 urea carboxylase compare
BWI76_RS14435 +0.5 0.8 glutamine ABC transporter ATP-binding protein compare
BWI76_RS19325 +0.5 0.7 mandelate racemase compare
BWI76_RS18550 +0.5 1.2 tRNA-Asn compare
BWI76_RS23000 +0.5 1.6 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
BWI76_RS15970 +0.5 1.8 carboxypeptidase M32 compare
BWI76_RS26470 +0.5 2.8 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS08755 +0.5 1.9 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
BWI76_RS22735 +0.5 1.8 type I-E CRISPR-associated protein Cas7/Cse4/CasC compare
BWI76_RS27510 +0.5 1.4 aquaporin compare
BWI76_RS14970 +0.5 1.0 pyrroline-5-carboxylate reductase compare
BWI76_RS02530 +0.5 0.7 tRNA dimethylallyltransferase compare
BWI76_RS14845 +0.5 1.6 hypothetical protein compare
BWI76_RS19480 +0.5 1.0 transcriptional regulator compare
BWI76_RS19190 +0.5 1.4 oligopeptide/dipeptide ABC transporter ATPase compare
BWI76_RS10275 +0.5 1.4 ABC transporter compare
BWI76_RS05880 +0.5 1.2 AraC-type DNA-binding domain-containing protein compare
BWI76_RS08880 +0.5 2.5 secretion protein HlyD compare
BWI76_RS11900 +0.5 0.8 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS25465 +0.5 1.9 transcriptional regulator compare
BWI76_RS11180 +0.5 2.5 hypothetical protein compare
BWI76_RS20885 +0.5 2.4 tRNA(Met) cytidine acetyltransferase TmcA compare
BWI76_RS25380 +0.5 1.5 oxaloacetate decarboxylase subunit beta compare
BWI76_RS15950 +0.5 0.7 dethiobiotin synthase compare
BWI76_RS16695 +0.5 3.0 dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein compare
BWI76_RS09390 +0.5 1.1 phage tail protein compare
BWI76_RS02695 +0.5 1.6 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS02150 +0.5 1.6 allulose-6-phosphate 3-epimerase compare
BWI76_RS25300 +0.5 1.3 hybrid sensor histidine kinase/response regulator compare
BWI76_RS15740 +0.4 0.8 HNH endonuclease compare
BWI76_RS06030 +0.4 1.7 homocysteine S-methyltransferase compare
BWI76_RS01775 +0.4 0.8 hypothetical protein compare
BWI76_RS21395 +0.4 0.9 DTW domain-containing protein compare
BWI76_RS17190 +0.4 1.0 TonB system transport protein TonB compare
BWI76_RS19775 +0.4 0.7 phage resistance protein compare
BWI76_RS14980 +0.4 0.8 hypothetical protein compare
BWI76_RS07780 +0.4 0.8 hypothetical protein compare
BWI76_RS27850 +0.4 1.9 DNA-binding transcriptional regulator DsdC compare
BWI76_RS13290 +0.4 1.4 protocatechuate 3,4-dioxygenase subunit beta compare
BWI76_RS16900 +0.4 1.1 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS05425 +0.4 1.4 EEP domain-containing protein compare
BWI76_RS01380 +0.4 1.2 YigZ family protein compare
BWI76_RS09275 +0.4 2.1 major capsid protein compare
BWI76_RS11125 +0.4 0.8 metal-dependent hydrolase compare
BWI76_RS23875 +0.4 1.4 glycine cleavage system protein H compare
BWI76_RS13410 +0.4 1.5 polyamine ABC transporter ATP-binding protein compare
BWI76_RS16865 +0.4 2.4 coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase-related flavin-dependent oxidoreductase compare
BWI76_RS11000 +0.4 1.8 glutaredoxin 2 compare
BWI76_RS05160 +0.4 1.5 hypothetical protein compare
BWI76_RS17285 +0.4 1.4 hypothetical protein compare
BWI76_RS16775 +0.4 1.2 malate/lactate/ureidoglycolate dehydrogenase compare
BWI76_RS07975 +0.4 1.5 phospholipid:lipid A palmitoyltransferase compare
BWI76_RS16990 +0.4 2.0 ABC transporter ATP-binding protein compare
BWI76_RS23945 +0.4 1.1 methylmalonyl-CoA decarboxylase compare
BWI76_RS12550 +0.4 0.9 hypothetical protein compare
BWI76_RS07590 +0.4 1.4 glutamate ABC transporter ATP-binding protein compare
BWI76_RS13135 +0.4 1.1 3-oxoadipyl-CoA thiolase compare
BWI76_RS03915 +0.4 2.0 MurR/RpiR family transcriptional regulator compare
BWI76_RS17235 +0.4 2.6 peptide ABC transporter permease compare
BWI76_RS21660 +0.4 1.0 antirestriction protein compare
BWI76_RS11365 +0.4 1.2 iron ABC transporter compare
BWI76_RS13265 +0.4 1.6 hypothetical protein compare


Specific Phenotypes

For 3 genes in this experiment

For stress Sodium Chloride in Klebsiella michiganensis M5al

For stress Sodium Chloride across organisms