Experiment set17IT019 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_1percent_glucose with Betaine 100 uM

200 most important genes:

  gene name fitness t score description  
BWI76_RS25115 -8.4 -5.8 argininosuccinate synthase compare
BWI76_RS18950 -8.3 -5.2 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS21475 -7.4 -7.2 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS07065 -6.7 -6.5 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS20965 -6.6 -3.6 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS18920 -6.6 -4.3 ATP phosphoribosyltransferase compare
BWI76_RS18930 -6.5 -5.7 histidinol-phosphate transaminase compare
BWI76_RS11850 -6.4 -8.8 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS00805 -6.4 -4.6 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS18925 -6.3 -6.9 histidinol dehydrogenase compare
BWI76_RS05835 -6.3 -4.1 gamma-glutamyl-phosphate reductase compare
BWI76_RS23360 -6.2 -3.9 diaminopimelate decarboxylase compare
BWI76_RS11965 -6.1 -4.0 orotidine-5'-phosphate decarboxylase compare
BWI76_RS04465 -5.9 -4.1 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04160 -5.8 -6.9 phosphoserine phosphatase compare
BWI76_RS05840 -5.8 -6.9 glutamate 5-kinase compare
BWI76_RS00990 -5.6 -7.3 ketol-acid reductoisomerase compare
BWI76_RS20355 -5.6 -3.1 colicin V production protein compare
BWI76_RS23920 -5.6 -6.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS01615 -5.6 -3.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS00850 -5.6 -8.6 acetylglutamate kinase compare
BWI76_RS02995 -5.6 -6.6 aspartate carbamoyltransferase compare
BWI76_RS00835 -5.5 -15.7 phosphoenolpyruvate carboxylase compare
BWI76_RS04470 -5.5 -8.4 carbamoyl phosphate synthase large subunit compare
BWI76_RS21265 -5.3 -10.8 phosphoribosylformylglycinamidine synthase compare
BWI76_RS04255 -5.2 -11.6 threonine synthase compare
BWI76_RS00855 -5.2 -9.5 argininosuccinate lyase compare
BWI76_RS09755 -5.1 -9.0 phosphoserine transaminase compare
BWI76_RS11840 -5.0 -5.8 tryptophan synthase subunit alpha compare
BWI76_RS04250 -5.0 -6.6 homoserine kinase compare
BWI76_RS04675 -5.0 -5.3 3-isopropylmalate dehydrogenase compare
BWI76_RS04665 -4.9 -19.1 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04670 -4.9 -13.0 3-isopropylmalate dehydratase large subunit compare
BWI76_RS24285 -4.8 -6.4 cystathionine beta-lyase compare
BWI76_RS00965 -4.7 -1.5 acetolactate synthase 2 small subunit compare
BWI76_RS04645 -4.7 -5.0 3-dehydroquinase compare
BWI76_RS26085 -4.6 -2.5 3-dehydroquinate synthase compare
BWI76_RS11860 -4.6 -10.8 anthranilate synthase component I compare
BWI76_RS18935 -4.6 -5.7 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00845 -4.5 -10.8 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS00980 -4.5 -9.7 PLP-dependent threonine dehydratase compare
BWI76_RS02735 -4.4 -6.1 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS23220 -4.4 -7.6 amino-acid N-acetyltransferase compare
BWI76_RS20895 -4.3 -5.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS09760 -4.3 -3.5 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS04245 -4.3 -14.8 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS01655 -4.3 -6.3 homoserine O-succinyltransferase compare
BWI76_RS12090 -4.2 -3.9 HNH endonuclease compare
BWI76_RS22765 -4.2 -14.2 sulfite reductase subunit alpha compare
BWI76_RS00975 -4.2 -7.9 dihydroxy-acid dehydratase compare
BWI76_RS25645 -4.2 -8.7 shikimate dehydrogenase compare
BWI76_RS07070 -4.2 -3.9 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS04680 -4.2 -10.8 2-isopropylmalate synthase compare
BWI76_RS23365 -4.1 -9.2 LysR family transcriptional regulator compare
BWI76_RS18955 -4.1 -6.6 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS22755 -4.1 -6.5 phosphoadenosine phosphosulfate reductase compare
BWI76_RS03010 -4.0 -6.9 ornithine carbamoyltransferase compare
BWI76_RS22760 -4.0 -7.2 sulfite reductase subunit beta compare
BWI76_RS00785 -3.9 -7.7 cystathionine gamma-synthase compare
BWI76_RS00985 -3.9 -7.1 transcriptional regulator IlvY compare
BWI76_RS11845 -3.8 -3.3 tryptophan synthase subunit beta compare
BWI76_RS20350 -3.8 -3.2 amidophosphoribosyltransferase compare
BWI76_RS01610 -3.8 -4.1 phosphoribosylamine--glycine ligase compare
BWI76_RS11855 -3.8 -6.2 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04685 -3.8 -7.2 putative leucine operon leader peptide compare
BWI76_RS08385 -3.6 -3.3 citrate (Si)-synthase compare
BWI76_RS09910 -3.6 -12.5 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS01200 -3.4 -2.3 diaminopimelate epimerase compare
BWI76_RS27385 -3.4 -7.3 orotate phosphoribosyltransferase compare
BWI76_RS18940 -3.3 -3.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS22690 -3.1 -4.5 adenylyl-sulfate kinase compare
BWI76_RS04240 -3.0 -3.1 thr operon leader peptide compare
BWI76_RS20435 -2.9 -1.3 chorismate synthase compare
BWI76_RS10990 -2.9 -2.8 dihydroorotase compare
BWI76_RS17805 -2.8 -1.8 membrane protein compare
BWI76_RS26000 -2.7 -5.9 aspartate aminotransferase family protein compare
BWI76_RS01800 -2.7 -4.7 glucose-6-phosphate isomerase compare
BWI76_RS21465 -2.6 -3.7 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS26055 -2.6 -6.4 siroheme synthase compare
BWI76_RS09645 -2.6 -1.1 thioredoxin-disulfide reductase compare
BWI76_RS14375 -2.5 -3.7 hypothetical protein compare
BWI76_RS05015 -2.5 -2.8 transcriptional regulator compare
BWI76_RS26570 -2.4 -3.8 anion permease compare
BWI76_RS25335 -2.3 -3.1 stringent starvation protein A compare
BWI76_RS27820 -2.2 -1.2 ilvB operon leader peptide IvbL compare
BWI76_RS22805 -2.1 -8.7 GTP diphosphokinase compare
BWI76_RS20640 -2.1 -3.7 cysteine synthase A compare
BWI76_RS01210 -1.9 -1.4 tyrosine recombinase XerC compare
BWI76_RS03595 -1.9 -1.6 ethanolamine utilization protein EutM compare
BWI76_RS10835 -1.8 -1.3 hypothetical protein compare
BWI76_RS09635 -1.8 -1.9 amino acid ABC transporter ATP-binding protein compare
BWI76_RS10060 -1.8 -1.9 acylphosphatase compare
BWI76_RS11440 -1.7 -1.6 hypothetical protein compare
BWI76_RS12895 -1.7 -1.6 hypothetical protein compare
BWI76_RS05200 -1.6 -2.7 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS13590 -1.6 -2.1 hypothetical protein compare
BWI76_RS21340 -1.6 -2.9 SoxR reducing system protein RseC compare
BWI76_RS27390 -1.6 -2.1 ribonuclease PH compare
BWI76_RS25320 -1.5 -5.5 glutamate synthase compare
BWI76_RS00960 -1.5 -3.3 acetolactate synthase 2 catalytic subunit compare
BWI76_RS20440 -1.5 -1.6 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS20995 -1.5 -1.4 RNA degradosome polyphosphate kinase compare
BWI76_RS02530 -1.5 -1.0 tRNA dimethylallyltransferase compare
BWI76_RS15830 -1.5 -2.7 hypothetical protein compare
BWI76_RS24180 -1.5 -2.2 hypothetical protein compare
BWI76_RS00400 -1.4 -0.8 glutamine synthetase compare
BWI76_RS00180 -1.4 -1.0 F0F1 ATP synthase subunit epsilon compare
BWI76_RS14915 -1.4 -2.0 hypothetical protein compare
BWI76_RS20375 -1.4 -1.7 membrane protein compare
BWI76_RS16275 -1.4 -2.8 fumarate hydratase FumA compare
BWI76_RS16555 -1.4 -2.5 hypothetical protein compare
BWI76_RS23480 -1.4 -6.8 EAL domain-containing protein compare
BWI76_RS17720 -1.3 -0.8 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS12070 -1.3 -1.2 hypothetical protein compare
BWI76_RS25315 -1.3 -5.9 glutamate synthase large subunit compare
BWI76_RS09650 -1.3 -3.9 hypothetical protein compare
BWI76_RS27430 -1.3 -1.0 (p)ppGpp synthetase compare
BWI76_RS01275 -1.3 -3.1 LysR family transcriptional regulator compare
BWI76_RS15835 -1.3 -1.1 hypothetical protein compare
BWI76_RS20970 -1.3 -1.3 phosphoribosylglycinamide formyltransferase compare
BWI76_RS22485 -1.2 -2.2 hypothetical protein compare
BWI76_RS15000 -1.2 -2.5 amino acid ABC transporter ATP-binding protein compare
BWI76_RS26390 -1.2 -2.0 cell division protein FtsX compare
BWI76_RS15680 -1.2 -2.3 hypothetical protein compare
BWI76_RS16935 -1.2 -1.2 shikimate dehydrogenase compare
BWI76_RS02985 -1.2 -1.4 reactive intermediate/imine deaminase compare
BWI76_RS11130 -1.2 -3.5 PTS glucose transporter subunit IIBC compare
BWI76_RS20150 -1.2 -2.2 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS09655 -1.2 -4.1 leucine-responsive regulatory protein compare
BWI76_RS21480 -1.2 -3.4 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS00355 -1.1 -2.3 DNA polymerase I compare
BWI76_RS09730 -1.1 -1.1 pyruvate formate lyase 1-activating protein compare
BWI76_RS03660 -1.1 -2.1 hypothetical protein compare
BWI76_RS00390 -1.1 -3.5 two-component system sensor histidine kinase NtrB compare
BWI76_RS24025 -1.1 -6.0 agmatinase compare
BWI76_RS06765 -1.1 -2.1 transcriptional regulator compare
BWI76_RS05915 -1.1 -1.7 helix-turn-helix transcriptional regulator compare
BWI76_RS09615 -1.1 -2.3 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS17180 -1.1 -1.6 hypothetical protein compare
BWI76_RS25920 -1.1 -0.8 peptidylprolyl isomerase compare
BWI76_RS23120 -1.1 -2.7 propanediol dehydratase medium subunit compare
BWI76_RS20650 -1.1 -0.7 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS17110 -1.1 -1.6 vitamin B12 ABC transporter permease BtuC compare
BWI76_RS14320 -1.1 -1.4 hypothetical protein compare
BWI76_RS22700 -1.0 -3.5 sulfate adenylyltransferase subunit 2 compare
BWI76_RS15810 -1.0 -3.1 hypothetical protein compare
BWI76_RS17165 -1.0 -3.1 hypothetical protein compare
BWI76_RS07865 -1.0 -1.2 methylthioribulose 1-phosphate dehydratase compare
BWI76_RS19900 -1.0 -2.4 FAD:protein FMN transferase compare
BWI76_RS17785 -1.0 -5.5 septum site-determining protein MinD compare
BWI76_RS15825 -1.0 -2.6 hypothetical protein compare
BWI76_RS24900 -1.0 -0.9 DeoR family transcriptional regulator compare
BWI76_RS25280 -1.0 -1.5 RNase adaptor protein RapZ compare
BWI76_RS15840 -1.0 -2.6 prophage protein compare
BWI76_RS08580 -1.0 -2.5 quinolinate synthetase compare
BWI76_RS22375 -1.0 -2.7 pectin acetylesterase compare
BWI76_RS00140 -1.0 -0.5 phosphate transport system regulator PhoU compare
BWI76_RS20940 -1.0 -2.1 uracil/xanthine transporter compare
BWI76_RS06830 -1.0 -1.7 recombination protein RecR compare
BWI76_RS18360 -1.0 -1.3 aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein compare
BWI76_RS25480 -1.0 -2.1 ribonuclease E/G compare
BWI76_RS01385 -1.0 -1.2 potassium transporter compare
BWI76_RS03380 -0.9 -4.5 hypothetical protein compare
BWI76_RS09520 -0.9 -1.8 arginine ABC transporter ATP-binding protein ArtP compare
BWI76_RS09250 -0.9 -2.0 hypothetical protein compare
BWI76_RS24575 -0.9 -0.8 hypothetical protein compare
BWI76_RS08530 -0.9 -1.3 protein TolA compare
BWI76_RS02855 -0.9 -1.4 cytochrome B562 compare
BWI76_RS01350 -0.9 -0.8 NAD(P)H-flavin reductase compare
BWI76_RS12460 -0.9 -1.8 envelope stress response membrane protein PspC compare
BWI76_RS19690 -0.9 -1.9 LysR family transcriptional regulator compare
BWI76_RS08665 -0.9 -4.1 6-phosphogluconolactonase compare
BWI76_RS26590 -0.9 -2.4 transcriptional regulator compare
BWI76_RS23885 -0.9 -0.9 2-octaprenylphenol hydroxylase compare
BWI76_RS07475 -0.9 -0.8 DNA-binding transcriptional regulator RamA compare
BWI76_RS00440 -0.8 -1.2 CopG family transcriptional regulator compare
BWI76_RS17190 -0.8 -1.5 TonB system transport protein TonB compare
BWI76_RS12610 -0.8 -2.9 LysR family transcriptional regulator compare
BWI76_RS03995 -0.8 -2.2 hypothetical protein compare
BWI76_RS06185 -0.8 -3.9 shikimate kinase II compare
BWI76_RS15430 -0.8 -2.5 hypothetical protein compare
BWI76_RS11390 -0.8 -1.6 iron dicitrate transport regulator FecR compare
BWI76_RS19870 -0.8 -1.2 malate:quinone oxidoreductase compare
BWI76_RS09610 -0.8 -1.6 ATP-dependent Clp protease adaptor ClpS compare
BWI76_RS13180 -0.8 -1.8 multidrug transporter EmrA compare
BWI76_RS16240 -0.8 -1.0 anti-adapter protein IraM compare
BWI76_RS01220 -0.8 -3.1 DNA-dependent helicase II compare
BWI76_RS08605 -0.8 -1.6 phosphoglyceromutase compare
BWI76_RS26890 -0.8 -1.0 hypothetical protein compare
BWI76_RS25070 -0.8 -0.8 hypothetical protein compare
BWI76_RS20490 -0.8 -1.2 hypothetical protein compare
BWI76_RS07645 -0.8 -1.3 short-chain dehydrogenase/reductase compare
BWI76_RS20360 -0.8 -0.9 cell division protein DedD compare
BWI76_RS00240 -0.8 -1.0 FMN-binding protein MioC compare
BWI76_RS20805 -0.8 -1.9 phosphate acetyltransferase compare
BWI76_RS17400 -0.8 -1.0 transporter compare
BWI76_RS25035 -0.8 -2.5 malonate transporter subunit MadM compare
BWI76_RS18550 -0.8 -1.2 tRNA-Asn compare
BWI76_RS01885 -0.8 -0.8 CsbD family protein compare
BWI76_RS19490 -0.7 -1.5 binding-protein-dependent transport system inner membrane protein compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in stress experiments

For stress Betaine across organisms