Experiment set17IT011 for Pseudomonas stutzeri RCH2

Compare to:

LB with Thallium(I) acetate 0.09 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_0623 -4.9 -16.8 Arsenite efflux pump ACR3 and related permeases conserved
Psest_0164 -4.7 -1.2 Glutaredoxin, GrxC family compare
Psest_1809 -4.7 -13.2 Membrane protein involved in the export of O-antigen and teichoic acid compare
Psest_1496 -4.2 -1.8 Holliday junction DNA helicase, RuvA subunit compare
Psest_0028 -3.8 -4.5 Coproporphyrinogen III oxidase compare
Psest_1814 -3.6 -21.0 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_3960 -3.1 -1.8 3'(2'),5'-bisphosphate nucleotidase, bacterial compare
Psest_3565 -3.1 -2.2 hypothetical protein compare
Psest_0309 -2.9 -1.8 RND family efflux transporter, MFP subunit compare
Psest_0515 -2.8 -4.3 rare lipoprotein A compare
Psest_1167 -2.8 -1.2 hypothetical protein compare
Psest_1657 -2.7 -2.3 NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit compare
Psest_4078 -2.7 -2.8 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D compare
Psest_1510 -2.6 -2.5 Putative Zn-dependent protease, contains TPR repeats compare
Psest_1661 -2.1 -2.0 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_2945 -2.1 -1.6 septum site-determining protein MinC compare
Psest_2946 -2.1 -3.2 septum site-determining protein MinD compare
Psest_0516 -2.1 -8.6 D-alanyl-D-alanine carboxypeptidase compare
Psest_3185 -2.1 -2.3 MoxR-like ATPases compare
Psest_1999 -2.0 -1.1 pseudouridine synthase compare
Psest_1774 -2.0 -2.6 Glutathione peroxidase compare
Psest_1012 -2.0 -4.9 Signal transduction histidine kinase compare
Psest_3351 -2.0 -5.8 peptide chain release factor 3 compare
Psest_0487 -2.0 -3.5 Uncharacterized protein conserved in bacteria compare
Psest_0845 -1.9 -1.0 hypothetical protein compare
Psest_0725 -1.9 -2.2 Negative regulator of beta-lactamase expression compare
Psest_2590 -1.9 -1.1 3-isopropylmalate dehydratase, small subunit compare
Psest_2285 -1.9 -3.3 ATP-dependent protease La compare
Psest_3247 -1.9 -1.6 Uncharacterized membrane protein compare
Psest_1860 -1.8 -2.7 Uncharacterized conserved protein compare
Psest_4325 -1.8 -2.2 hypothetical protein compare
Psest_4338 -1.8 -5.1 Fe2+-dicitrate sensor, membrane component compare
Psest_3890 -1.8 -1.8 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_4010 -1.8 -1.1 peroxiredoxin, OsmC subfamily compare
Psest_0013 -1.7 -4.8 Lauroyl/myristoyl acyltransferase compare
Psest_2651 -1.7 -4.1 DNA topoisomerase I, bacterial compare
Psest_0514 -1.7 -5.6 lytic murein transglycosylase B compare
Psest_0078 -1.6 -1.3 hypothetical protein compare
Psest_1179 -1.6 -1.9 2-hydroxy-3-oxopropionate reductase compare
Psest_0442 -1.6 -3.7 ATPases of the AAA+ class compare
Psest_2001 -1.6 -1.1 2-phosphoglycolate phosphatase, prokaryotic compare
Psest_2786 -1.6 -1.0 Domain of unknown function (DUF3597). compare
Psest_3323 -1.6 -3.8 ribonuclease, Rne/Rng family compare
Psest_2764 -1.6 -1.3 hypothetical protein compare
Psest_0958 -1.6 -5.9 Oligoketide cyclase/lipid transport protein compare
Psest_4098 -1.6 -3.2 Superfamily I DNA and RNA helicases compare
Psest_0119 -1.6 -2.4 hypothetical protein compare
Psest_1986 -1.6 -1.0 3-phosphoshikimate 1-carboxyvinyltransferase compare
Psest_2566 -1.5 -0.9 Uncharacterized protein conserved in bacteria compare
Psest_2581 -1.5 -1.4 Uncharacterized protein conserved in bacteria compare
Psest_3301 -1.5 -2.4 Predicted transcriptional regulator, BolA superfamily compare
Psest_1471 -1.5 -5.3 Predicted membrane protein compare
Psest_3100 -1.5 -1.0 RNA polymerase sigma factor RpoE compare
Psest_3546 -1.4 -1.1 Phosphatidylglycerophosphatase A and related proteins compare
Psest_2454 -1.4 -1.8 Rhodanese-related sulfurtransferase compare
Psest_3395 -1.4 -1.1 hypothetical protein compare
Psest_1013 -1.4 -2.8 phosphoribosylamine--glycine ligase compare
Psest_4044 -1.4 -1.4 type I site-specific deoxyribonuclease, HsdR family compare
Psest_0511 -1.4 -1.5 rRNA large subunit m3Psi methyltransferase RlmH compare
Psest_1082 -1.4 -1.9 Enoyl-CoA hydratase/carnithine racemase compare
Psest_2253 -1.4 -2.1 small redox-active disulfide protein 2 compare
Psest_0060 -1.3 -1.6 Predicted Fe-S protein compare
Psest_2775 -1.3 -3.0 Glycerol-3-phosphate dehydrogenase compare
Psest_2850 -1.3 -1.3 Multisubunit Na+/H+ antiporter, MnhC subunit compare
Psest_3400 -1.3 -1.1 Copper resistance protein D. compare
Psest_3316 -1.3 -5.2 Predicted P-loop-containing kinase compare
Psest_2579 -1.3 -4.5 amidophosphoribosyltransferase compare
Psest_3322 -1.3 -9.3 TIGR02099 family protein compare
Psest_0417 -1.3 -2.1 Acyl-CoA dehydrogenases compare
Psest_3128 -1.3 -3.5 Protein-disulfide isomerase compare
Psest_4067 -1.3 -2.6 Predicted membrane protein compare
Psest_0466 -1.3 -2.7 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_0644 -1.3 -2.1 siderophore ferric iron reductase, AHA_1954 family compare
Psest_3188 -1.2 -3.0 hypothetical protein compare
Psest_1679 -1.2 -1.1 ribonuclease, Rne/Rng family compare
Psest_1782 -1.2 -1.3 Predicted transcriptional regulators compare
Psest_4343 -1.2 -2.1 Protein of unknown function (DUF3301). compare
Psest_3995 -1.2 -2.3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0508 -1.2 -4.0 gamma-glutamyl phosphate reductase compare
Psest_1115 -1.2 -1.8 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_3156 -1.1 -3.2 Site-specific recombinases, DNA invertase Pin homologs compare
Psest_3226 -1.1 -0.8 Predicted membrane protein compare
Psest_1704 -1.1 -1.2 Dehydrogenases (flavoproteins) compare
Psest_2983 -1.1 -1.9 hypothetical protein compare
Psest_2585 -1.1 -0.7 pseudouridylate synthase I compare
Psest_1813 -1.1 -4.8 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_3754 -1.1 -2.0 Uncharacterized protein involved in response to NO compare
Psest_3292 -1.1 -2.7 hypothetical protein compare
Psest_3767 -1.1 -2.3 tyrosine recombinase XerC compare
Psest_3361 -1.1 -2.8 Uncharacterized protein conserved in bacteria compare
Psest_4090 -1.0 -1.7 diaminobutyrate acetyltransferase compare
Psest_3749 -1.0 -5.5 Response regulator of the LytR/AlgR family compare
Psest_3270 -1.0 -1.4 probable S-adenosylmethionine-dependent methyltransferase, YraL family compare
Psest_3331 -1.0 -3.2 rare lipoprotein A compare
Psest_2648 -1.0 -1.5 hypothetical protein compare
Psest_3480 -1.0 -1.5 molybdenum cofactor biosynthesis protein B, proteobacterial compare
Psest_1354 -1.0 -1.1 Uncharacterized protein conserved in bacteria compare
Psest_0172 -1.0 -3.1 Uncharacterized protein conserved in bacteria compare
Psest_3991 -1.0 -1.6 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
Psest_2280 -1.0 -2.7 Predicted membrane protein compare
Psest_1295 -1.0 -3.7 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_2044 -1.0 -3.0 ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system compare
Psest_4045 -1.0 -2.9 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen compare
Psest_0533 -1.0 -2.6 Sel1 repeat. compare
Psest_1695 -1.0 -2.2 Tfp pilus assembly protein PilZ compare
Psest_4371 -1.0 -2.1 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_1870 -1.0 -0.7 Transcriptional regulators compare
Psest_0334 -0.9 -1.8 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_4184 -0.9 -2.8 hypothetical protein compare
Psest_0457 -0.9 -1.8 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_0843 -0.9 -4.5 hypothetical protein compare
Psest_3938 -0.9 -1.6 Uncharacterized protein conserved in bacteria compare
Psest_1149 -0.9 -1.5 Protein affecting phage T7 exclusion by the F plasmid compare
Psest_3421 -0.9 -2.0 hypothetical protein compare
Psest_1261 -0.9 -2.7 Uncharacterized protein conserved in bacteria compare
Psest_3693 -0.9 -1.7 Glycosyltransferases involved in cell wall biogenesis compare
Psest_2793 -0.9 -2.1 hypothetical protein compare
Psest_2434 -0.9 -2.1 Protein of unknown function (DUF2892). compare
Psest_2225 -0.9 -1.5 Diacylglycerol kinase compare
Psest_0191 -0.9 -0.4 PAS domain S-box compare
Psest_1505 -0.9 -1.5 Organic radical activating enzymes compare
Psest_0609 -0.9 -0.9 hypothetical protein compare
Psest_4406 -0.9 -0.8 hypothetical protein compare
Psest_4309 -0.9 -2.6 ABC-type Mn/Zn transport systems, ATPase component compare
Psest_0717 -0.9 -6.6 Protein of unknown function (DUF1631). compare
Psest_1302 -0.9 -2.2 Predicted thioesterase compare
Psest_3180 -0.9 -4.0 Exonuclease I compare
Psest_2104 -0.9 -0.8 IscR-regulated protein YhgI compare
Psest_2120 -0.9 -1.3 Transcriptional regulator compare
Psest_3496 -0.9 -1.1 Predicted metal-binding protein compare
Psest_0165 -0.9 -1.9 protein-export chaperone SecB compare
Psest_1551 -0.9 -1.4 Integral membrane protein, interacts with FtsH compare
Psest_2017 -0.8 -1.5 Predicted acyltransferase compare
Psest_2794 -0.8 -2.4 Predicted permease, DMT superfamily compare
Psest_0505 -0.8 -2.5 Putative effector of murein hydrolase compare
Psest_4342 -0.8 -2.1 Putative GTPases (G3E family) compare
Psest_3367 -0.8 -0.9 translation initation factor SUI1, putative, prokaryotic compare
Psest_4274 -0.8 -1.5 hypothetical protein compare
Psest_2772 -0.8 -2.5 MIP family channel proteins compare
Psest_2425 -0.8 -2.0 Trk-type K+ transport systems, membrane components compare
Psest_0919 -0.8 -1.3 Permeases of the drug/metabolite transporter (DMT) superfamily compare
Psest_3832 -0.8 -1.3 hypothetical protein compare
Psest_0526 -0.8 -2.2 hypothetical protein compare
Psest_3181 -0.8 -2.9 Predicted membrane protein/domain compare
Psest_2525 -0.8 -2.4 cytochrome c oxidase, cbb3-type, subunit II compare
Psest_2736 -0.8 -2.0 Transposase and inactivated derivatives compare
Psest_1142 -0.8 -2.0 Uncharacterized protein conserved in bacteria compare
Psest_0359 -0.8 -1.4 Transcriptional regulators compare
Psest_3660 -0.8 -4.2 PAS domain S-box compare
Psest_1159 -0.8 -3.7 Uncharacterized iron-regulated protein compare
Psest_2852 -0.8 -2.3 Outer membrane lipoprotein compare
Psest_1997 -0.8 -1.1 6-phosphogluconolactonase compare
Psest_3984 -0.8 -2.9 Methyl-accepting chemotaxis protein compare
Psest_3236 -0.8 -1.9 hypothetical protein compare
Psest_1087 -0.8 -0.4 uncharacterized peroxidase-related enzyme compare
Psest_4187 -0.8 -2.7 Predicted permeases compare
Psest_2779 -0.8 -2.1 Methyl-accepting chemotaxis protein compare
Psest_3780 -0.8 -2.5 Transcriptional regulator compare
Psest_2281 -0.8 -3.0 Phosphoserine aminotransferase compare
Psest_3148 -0.8 -0.6 hypothetical protein compare
Psest_0837 -0.8 -1.4 Putative lipid carrier protein compare
Psest_0601 -0.8 -0.9 hypothetical protein compare
Psest_0297 -0.8 -2.0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_3961 -0.8 -2.7 NTP pyrophosphohydrolases including oxidative damage repair enzymes compare
Psest_1692 -0.7 -3.1 conserved hypothetical protein, YceG family compare
Psest_1417 -0.7 -0.8 hypothetical protein compare
Psest_0212 -0.7 -1.2 exodeoxyribonuclease V, gamma subunit compare
Psest_1516 -0.7 -1.2 Uncharacterized lipoprotein compare
Psest_1660 -0.7 -1.0 NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit compare
Psest_4099 -0.7 -4.6 TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component compare
Psest_1259 -0.7 -2.5 23S rRNA m2A2503 methyltransferase compare
Psest_1163 -0.7 -2.0 diguanylate cyclase (GGDEF) domain compare
Psest_2048 -0.7 -1.4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_2041 -0.7 -2.5 ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system compare
Psest_3334 -0.7 -2.2 Integral membrane protein CcmA involved in cell shape determination compare
Psest_1597 -0.7 -1.8 Protein of unknown function (DUF2933). compare
Psest_0073 -0.7 -2.0 ABC-type multidrug transport system, ATPase and permease components compare
Psest_1472 -0.7 -3.2 Protein of unknown function (DUF3108). compare
Psest_1899 -0.7 -2.8 ABC-type sugar transport systems, ATPase components compare
Psest_3707 -0.7 -1.4 Transcriptional regulator compare
Psest_0719 -0.7 -2.5 Uncharacterized protein conserved in bacteria compare
Psest_1681 -0.7 -2.1 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E compare
Psest_1805 -0.7 -1.0 integration host factor, beta subunit compare
Psest_2773 -0.7 -3.0 glycerol kinase compare
Psest_3177 -0.7 -0.8 hypothetical protein compare
Psest_2360 -0.7 -3.1 Uncharacterized protein, putative amidase compare
Psest_2911 -0.7 -1.0 Protein of unknown function (DUF2945). compare
Psest_3896 -0.7 -1.6 arsenite-activated ATPase ArsA compare
Psest_0575 -0.7 -0.5 HrpA-like helicases compare
Psest_0266 -0.7 -2.1 thiamine biosynthesis protein ThiS compare
Psest_1947 -0.7 -0.8 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_0708 -0.7 -0.7 outer membrane assembly lipoprotein YfiO compare
Psest_0088 -0.7 -2.5 phosphonate metabolism protein PhnP compare
Psest_4064 -0.7 -0.9 Lactate dehydrogenase and related dehydrogenases compare
Psest_1804 -0.7 -1.2 Superfamily II DNA and RNA helicases compare
Psest_3207 -0.7 -2.3 HopJ type III effector protein. compare
Psest_3014 -0.7 -0.8 cob(I)alamin adenosyltransferase compare
Psest_0647 -0.7 -2.7 Arabinose efflux permease compare
Psest_0790 -0.7 -1.3 Uncharacterized protein conserved in bacteria compare
Psest_0846 -0.7 -1.5 Uncharacterized protein probably involved in high-affinity Fe2+ transport compare


Specific Phenotypes

For 3 genes in this experiment

For stress Thallium(I) acetate in Pseudomonas stutzeri RCH2

For stress Thallium(I) acetate across organisms