Experiment set17IT011 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_1percent_glucose with Sodium Chloride 200 mM and Betaine 100 uM

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS18755 +1.7 2.6 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS03665 +1.6 1.4 ABC transporter ATP-binding protein compare
BWI76_RS08315 +1.5 2.8 K+-transporting ATPase subunit B compare
BWI76_RS21310 +1.2 1.5 DNA repair protein RecO compare
BWI76_RS01210 +1.2 1.1 tyrosine recombinase XerC compare
BWI76_RS23320 +1.1 2.4 hypothetical protein compare
BWI76_RS10575 +1.1 2.1 polar amino acid ABC transporter permease compare
BWI76_RS11255 +1.0 1.2 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS06250 +1.0 3.2 alpha-glycosidase compare
BWI76_RS20750 +1.0 1.4 carboxysome structural protein EutK compare
BWI76_RS08040 +1.0 2.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
BWI76_RS21460 +1.0 1.6 translation inhibitor protein RaiA compare
BWI76_RS06680 +1.0 1.4 hypothetical protein compare
BWI76_RS17155 +1.0 2.1 hypothetical protein compare
BWI76_RS21450 +1.0 1.3 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS25870 +1.0 1.8 elongation factor Tu compare
BWI76_RS18410 +1.0 1.9 drug/metabolite exporter YedA compare
BWI76_RS15845 +1.0 1.1 hypothetical protein compare
BWI76_RS16815 +1.0 2.6 periplasmic binding protein compare
BWI76_RS08320 +1.0 5.6 potassium-transporting ATPase subunit KdpA compare
BWI76_RS13095 +1.0 2.0 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS15035 +1.0 1.6 metal ABC transporter permease compare
BWI76_RS05810 +1.0 1.6 hypothetical protein compare
BWI76_RS14040 +0.9 1.3 thiaminase compare
BWI76_RS05520 +0.9 3.0 hypothetical protein compare
BWI76_RS25600 +0.9 1.1 tRNA-Thr compare
BWI76_RS17525 +0.9 1.7 XshC-Cox1-family protein compare
BWI76_RS01935 +0.9 2.7 thiamin phosphate synthase compare
BWI76_RS21390 +0.9 2.7 thiol disulfide reductase thioredoxin compare
BWI76_RS06340 +0.9 1.3 hypothetical protein compare
BWI76_RS15205 +0.9 2.5 succinate-semialdehyde dehydrogenase compare
BWI76_RS11815 +0.9 1.5 hypothetical protein compare
BWI76_RS14935 +0.8 1.3 NIPSNAP family containing protein compare
BWI76_RS10530 +0.8 2.2 GntR family transcriptional regulator with compare
BWI76_RS08820 +0.8 2.9 molybdenum cofactor biosynthesis protein compare
BWI76_RS11900 +0.8 1.4 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS15190 +0.8 3.1 GGDEF domain-containing protein compare
BWI76_RS14670 +0.8 1.7 hypothetical protein compare
BWI76_RS08305 +0.8 5.1 two-component sensor histidine kinase compare
BWI76_RS11125 +0.8 1.4 metal-dependent hydrolase compare
BWI76_RS21245 +0.8 2.7 nitrogen regulatory protein P-II compare
BWI76_RS16260 +0.8 1.7 two-component sensor histidine kinase compare
BWI76_RS20460 +0.8 2.5 acetyl-CoA C-acyltransferase FadI compare
BWI76_RS05790 +0.8 1.6 phage DNA-binding protein compare
BWI76_RS16220 +0.8 1.7 hypothetical protein compare
BWI76_RS13960 +0.8 1.7 urea ABC transporter periplasmic protein compare
BWI76_RS16895 +0.8 1.6 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS02725 +0.8 1.1 HxlR family transcriptional regulator compare
BWI76_RS11435 +0.8 1.7 hypothetical protein compare
BWI76_RS06815 +0.8 2.1 adenine phosphoribosyltransferase compare
BWI76_RS16075 +0.8 1.3 oxidoreductase compare
BWI76_RS02870 +0.8 2.6 hypothetical protein compare
BWI76_RS24330 +0.8 1.7 TIGR00156 family protein compare
BWI76_RS14820 +0.8 1.9 LysR family transcriptional regulator compare
BWI76_RS07985 +0.8 1.2 fluoride ion transporter CrcB compare
BWI76_RS16000 +0.8 1.2 multidrug transporter subunit MdtI compare
BWI76_RS11835 +0.8 1.9 putative regulatory protein MarR compare
BWI76_RS26405 +0.8 1.1 16S rRNA (guanine(966)-N(2))-methyltransferase compare
BWI76_RS15940 +0.8 2.0 DMSO reductase maturation protein DsmD compare
BWI76_RS02090 +0.8 1.9 membrane protein compare
BWI76_RS15195 +0.8 1.2 DUF4186 domain-containing protein compare
BWI76_RS17665 +0.8 2.3 proteasome-type protease compare
BWI76_RS20000 +0.7 1.7 competence/damage-inducible protein A compare
BWI76_RS13380 +0.7 1.6 hypothetical protein compare
BWI76_RS20900 +0.7 1.3 outer membrane protein assembly factor BamC compare
BWI76_RS12870 +0.7 1.0 putative phytanoyl-CoA dioxygenase compare
BWI76_RS24940 +0.7 2.5 hypothetical protein compare
BWI76_RS01540 +0.7 1.4 thiamine biosynthesis protein ThiS compare
BWI76_RS14375 +0.7 1.5 hypothetical protein compare
BWI76_RS07380 +0.7 1.5 hypothetical protein compare
BWI76_RS20885 +0.7 2.7 tRNA(Met) cytidine acetyltransferase TmcA compare
BWI76_RS22090 +0.7 1.0 transcriptional regulator compare
BWI76_RS06290 +0.7 1.7 ACP phosphodiesterase compare
BWI76_RS14505 +0.7 1.2 salicylate synthase Irp9 compare
BWI76_RS13320 +0.7 2.5 putative LpxA-like enzyme compare
BWI76_RS11055 +0.7 1.6 hydrolase compare
BWI76_RS07815 +0.7 1.8 hypothetical protein compare
BWI76_RS17565 +0.7 1.2 hypothetical protein compare
BWI76_RS08360 +0.7 1.0 LamB/YcsF family protein compare
BWI76_RS20390 +0.7 1.3 erythronate-4-phosphate dehydrogenase compare
BWI76_RS23875 +0.7 1.9 glycine cleavage system protein H compare
BWI76_RS21945 +0.7 2.0 LysR family transcriptional regulator compare
BWI76_RS16025 +0.7 1.5 triphosphoribosyl-dephospho-CoA synthase compare
BWI76_RS09970 +0.7 0.8 porin OmpA compare
BWI76_RS07855 +0.7 1.6 PucR family transcriptional regulator compare
BWI76_RS21675 +0.7 1.1 hypothetical protein compare
BWI76_RS19550 +0.7 1.6 phospho-cellobiase compare
BWI76_RS22475 +0.7 1.9 heme ABC transporter ATP-binding protein compare
BWI76_RS10730 +0.7 1.1 bifunctional glucose-1-phosphatase/inositol phosphatase compare
BWI76_RS10665 +0.7 3.1 PTS system fructose-like transporter subunit EIIB compare
BWI76_RS12515 +0.7 1.8 protease compare
BWI76_RS03870 +0.7 1.9 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase compare
BWI76_RS01905 +0.6 1.1 envelope stress response protein PspG compare
BWI76_RS15980 +0.6 1.6 lysine transporter LysE compare
BWI76_RS08655 +0.6 1.4 molybdenum ABC transporter ATP-binding protein compare
BWI76_RS07545 +0.6 1.9 amidase compare
BWI76_RS08585 +0.6 2.3 nicotinamide riboside transporter PnuC compare
BWI76_RS12470 +0.6 1.1 thiosulfate sulfurtransferase PspE compare
BWI76_RS16205 +0.6 1.9 NAD(P) transhydrogenase subunit alpha compare
BWI76_RS20720 +0.6 1.4 hypothetical protein compare
BWI76_RS00240 +0.6 1.2 FMN-binding protein MioC compare
BWI76_RS16335 +0.6 1.1 division septum protein Blr compare
BWI76_RS15930 +0.6 2.2 dimethylsulfoxide reductase, chain B compare
BWI76_RS24040 +0.6 1.2 hypothetical protein compare
BWI76_RS08310 +0.6 1.7 potassium-transporting ATPase subunit C compare
BWI76_RS05075 +0.6 0.8 type II secretion system protein GspG compare
BWI76_RS08645 +0.6 1.5 molybdate ABC transporter substrate-binding protein compare
BWI76_RS11780 +0.6 1.7 2-deoxyglucose-6-phosphatase compare
BWI76_RS05640 +0.6 2.2 GntR family transcriptional regulator compare
BWI76_RS15215 +0.6 0.8 N-acetyltransferase compare
BWI76_RS02815 +0.6 1.6 fructose-bisphosphatase class I compare
BWI76_RS18810 +0.6 1.6 nitrogenase iron protein compare
BWI76_RS12420 +0.6 0.8 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS09630 +0.6 1.9 leucyl/phenylalanyl-tRNA--protein transferase compare
BWI76_RS22200 +0.6 1.9 iron ABC transporter compare
BWI76_RS13630 +0.6 1.1 ABC transporter compare
BWI76_RS26335 +0.6 1.3 ABC transporter ATP-binding protein compare
BWI76_RS13330 +0.6 1.0 tellurite resistance methyltransferase TehB compare
BWI76_RS05510 +0.6 1.2 NADH:ubiquinone reductase (Na(+)-transporting) subunit E compare
BWI76_RS15965 +0.6 2.0 MFS transporter compare
BWI76_RS02920 +0.6 1.7 addiction module toxin RelE compare
BWI76_RS09530 +0.6 0.7 hypothetical protein compare
BWI76_RS20930 +0.6 1.1 arsenate reductase (glutaredoxin) compare
BWI76_RS20795 +0.6 0.9 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS21445 +0.6 1.8 hypothetical protein compare
BWI76_RS03300 +0.6 2.7 hypothetical protein compare
BWI76_RS21200 +0.6 2.4 aldose epimerase compare
BWI76_RS15925 +0.6 2.1 dimethyl sulfoxide reductase subunit A compare
BWI76_RS04625 +0.6 1.6 glucose uptake inhibitor SgrT compare
BWI76_RS11155 +0.6 0.7 penicillin-binding protein activator LpoB compare
BWI76_RS23580 +0.6 1.0 hypothetical protein compare
BWI76_RS13530 +0.6 2.7 amidohydrolase family protein compare
BWI76_RS08520 +0.6 1.1 colicin transporter TolQ compare
BWI76_RS01105 +0.6 2.2 glucose-1-phosphate thymidylyltransferase compare
BWI76_RS21690 +0.6 0.8 hypothetical protein compare
BWI76_RS23755 +0.5 2.1 transcriptional regulator compare
BWI76_RS12480 +0.5 1.6 TIGR01620 family protein compare
BWI76_RS11035 +0.5 1.7 putative LysR-family transcriptional regulator compare
BWI76_RS14215 +0.5 1.5 hypothetical protein compare
BWI76_RS12735 +0.5 1.8 phage repressor protein compare
BWI76_RS23880 +0.5 1.8 Aminomethyltransferase (EC 2.1.2.10) (from data) compare
BWI76_RS16870 +0.5 1.3 LysR family transcriptional regulator compare
BWI76_RS26665 +0.5 1.9 DNA-binding response regulator compare
BWI76_RS02200 +0.5 1.3 phosphonate C-P lyase system protein PhnL compare
BWI76_RS16495 +0.5 1.7 endopeptidase compare
BWI76_RS20755 +0.5 1.0 microcompartment protein EutL compare
BWI76_RS23150 +0.5 2.0 propanediol utilization phosphotransacylase compare
BWI76_RS17405 +0.5 2.1 cation transport regulator compare
BWI76_RS10950 +0.5 1.2 MFS transporter compare
BWI76_RS25630 +0.5 1.7 hypothetical protein compare
BWI76_RS19965 +0.5 2.4 sn-glycerol-3-phosphate dehydrogenase subunit A compare
BWI76_RS00880 +0.5 2.4 membrane protein compare
BWI76_RS18425 +0.5 1.3 phosphohydrolase compare
BWI76_RS12545 +0.5 0.6 hypothetical protein compare
BWI76_RS14825 +0.5 1.2 dienelactone hydrolase family protein compare
BWI76_RS00715 +0.5 1.6 two-component sensor histidine kinase compare
BWI76_RS13175 +0.5 1.1 NodT family RND efflux system outer membrane lipoprotein compare
BWI76_RS24540 +0.5 1.9 hypothetical protein compare
BWI76_RS23020 +0.5 0.6 cobalamin biosynthesis protein CbiQ compare
BWI76_RS03810 +0.5 2.3 GTPase compare
BWI76_RS24825 +0.5 0.6 2-hydroxy-3-oxopropionate reductase compare
BWI76_RS16740 +0.5 2.1 transcriptional regulator compare
BWI76_RS14155 +0.5 1.8 transketolase compare
BWI76_RS01775 +0.5 0.8 hypothetical protein compare
BWI76_RS12600 +0.5 1.7 MFS transporter compare
BWI76_RS05870 +0.5 1.8 ABC transporter compare
BWI76_RS19480 +0.5 0.9 transcriptional regulator compare
BWI76_RS09705 +0.5 1.7 transketolase compare
BWI76_RS17985 +0.5 1.6 hypothetical protein compare
BWI76_RS06740 +0.5 1.2 50S ribosomal protein L36 compare
BWI76_RS22640 +0.5 1.2 hypothetical protein compare
BWI76_RS03015 +0.5 1.3 RNase E inhibitor protein compare
BWI76_RS18125 +0.5 1.5 murein DD-endopeptidase MepM compare
BWI76_RS03560 +0.5 2.1 propanediol utilization phosphotransacylase compare
BWI76_RS19755 +0.5 2.1 fructuronate reductase compare
BWI76_RS06190 +0.5 1.3 hypothetical protein compare
BWI76_RS24965 +0.5 1.5 SCP2 domain-containing protein compare
BWI76_RS18420 +0.5 3.1 DNA (cytosine-5-)-methyltransferase compare
BWI76_RS13415 +0.5 1.3 spermidine/putrescine ABC transporter permease compare
BWI76_RS03295 +0.5 1.1 transposase compare
BWI76_RS23015 +0.5 1.0 cobalt transporter ATP-binding subunit compare
BWI76_RS05880 +0.5 1.0 AraC-type DNA-binding domain-containing protein compare
BWI76_RS19465 +0.5 1.1 hypothetical protein compare
BWI76_RS14950 +0.5 1.6 glycosylasparaginase compare
BWI76_RS10890 +0.5 1.2 glyoxylate/hydroxypyruvate reductase A compare
BWI76_RS17770 +0.5 0.7 isomerase/hydrolase compare
BWI76_RS10500 +0.5 1.0 flavoprotein monooxygenase compare
BWI76_RS16190 +0.5 1.5 universal stress protein UspE compare
BWI76_RS15675 +0.5 2.3 hypothetical protein compare
BWI76_RS15350 +0.5 0.8 hypothetical protein compare
BWI76_RS07920 +0.5 1.6 methionine aminotransferase compare
BWI76_RS23055 +0.5 1.4 cobalamin biosynthesis protein CbiG compare
BWI76_RS11170 +0.5 0.8 hypothetical protein compare
BWI76_RS14975 +0.5 1.0 glyoxalase-like domain protein compare
BWI76_RS19525 +0.5 1.8 D-alanyl-D-alanine endopeptidase compare
BWI76_RS19960 +0.5 1.8 MFS transporter compare
BWI76_RS14770 +0.5 0.7 PTS IIA 2 domain protein compare
BWI76_RS12855 +0.5 1.1 enamine deaminase RidA compare
BWI76_RS23820 +0.5 1.6 flavodoxin FldB compare
BWI76_RS22950 +0.5 1.2 membrane protein compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in stress experiments

For stress Sodium Chloride across organisms