Experiment set17IT009 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_1percent_glucose with Betaine 100 uM

200 most important genes:

  gene name fitness t score description  
BWI76_RS00850 -7.6 -9.8 acetylglutamate kinase compare
BWI76_RS00855 -6.8 -9.3 argininosuccinate lyase compare
BWI76_RS21475 -6.5 -7.7 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS18920 -6.4 -4.4 ATP phosphoribosyltransferase compare
BWI76_RS18925 -6.0 -4.5 histidinol dehydrogenase compare
BWI76_RS04465 -5.7 -3.9 carbamoyl-phosphate synthase small subunit compare
BWI76_RS11965 -5.7 -3.9 orotidine-5'-phosphate decarboxylase compare
BWI76_RS02995 -5.6 -5.4 aspartate carbamoyltransferase compare
BWI76_RS18940 -5.5 -5.6 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS20355 -5.4 -3.2 colicin V production protein compare
BWI76_RS04255 -5.4 -10.7 threonine synthase compare
BWI76_RS04470 -5.3 -7.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS00805 -5.3 -5.8 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS18930 -5.1 -3.7 histidinol-phosphate transaminase compare
BWI76_RS18935 -5.1 -6.6 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS23360 -5.0 -4.8 diaminopimelate decarboxylase compare
BWI76_RS20965 -5.0 -4.0 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS25115 -5.0 -7.1 argininosuccinate synthase compare
BWI76_RS18950 -4.9 -3.5 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS01655 -4.8 -6.3 homoserine O-succinyltransferase compare
BWI76_RS23220 -4.8 -6.1 amino-acid N-acetyltransferase compare
BWI76_RS09755 -4.7 -7.8 phosphoserine transaminase compare
BWI76_RS05835 -4.7 -3.9 gamma-glutamyl-phosphate reductase compare
BWI76_RS20895 -4.4 -4.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS26085 -4.4 -2.6 3-dehydroquinate synthase compare
BWI76_RS03010 -4.3 -8.0 ornithine carbamoyltransferase compare
BWI76_RS21265 -4.3 -11.3 phosphoribosylformylglycinamidine synthase compare
BWI76_RS18955 -4.3 -4.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS04250 -4.1 -7.4 homoserine kinase compare
BWI76_RS04160 -4.1 -6.4 phosphoserine phosphatase compare
BWI76_RS00990 -4.0 -9.2 ketol-acid reductoisomerase compare
BWI76_RS05840 -4.0 -5.1 glutamate 5-kinase compare
BWI76_RS01615 -4.0 -7.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS04675 -3.9 -6.1 3-isopropylmalate dehydrogenase compare
BWI76_RS11840 -3.9 -6.9 tryptophan synthase subunit alpha compare
BWI76_RS07070 -3.9 -4.6 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS15360 -3.9 -2.7 hypothetical protein compare
BWI76_RS04645 -3.8 -4.7 3-dehydroquinase compare
BWI76_RS27385 -3.8 -5.6 orotate phosphoribosyltransferase compare
BWI76_RS09645 -3.8 -1.3 thioredoxin-disulfide reductase compare
BWI76_RS00785 -3.7 -6.0 cystathionine gamma-synthase compare
BWI76_RS20350 -3.7 -3.4 amidophosphoribosyltransferase compare
BWI76_RS04245 -3.7 -14.8 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04665 -3.7 -19.1 3-isopropylmalate dehydratase small subunit compare
BWI76_RS23920 -3.7 -3.3 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00845 -3.6 -5.9 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS24285 -3.5 -5.6 cystathionine beta-lyase compare
BWI76_RS00975 -3.4 -11.3 dihydroxy-acid dehydratase compare
BWI76_RS11860 -3.4 -4.9 anthranilate synthase component I compare
BWI76_RS11845 -3.4 -3.2 tryptophan synthase subunit beta compare
BWI76_RS11855 -3.4 -7.3 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS01610 -3.4 -4.0 phosphoribosylamine--glycine ligase compare
BWI76_RS04305 -3.3 -1.7 molecular chaperone DnaJ compare
BWI76_RS04670 -3.3 -8.9 3-isopropylmalate dehydratase large subunit compare
BWI76_RS01210 -3.3 -1.9 tyrosine recombinase XerC compare
BWI76_RS22765 -3.3 -12.9 sulfite reductase subunit alpha compare
BWI76_RS00835 -3.3 -9.6 phosphoenolpyruvate carboxylase compare
BWI76_RS01200 -3.3 -2.2 diaminopimelate epimerase compare
BWI76_RS20995 -3.2 -3.2 RNA degradosome polyphosphate kinase compare
BWI76_RS22690 -3.2 -3.4 adenylyl-sulfate kinase compare
BWI76_RS09760 -3.1 -2.4 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS23365 -3.0 -4.4 LysR family transcriptional regulator compare
BWI76_RS04685 -3.0 -6.4 putative leucine operon leader peptide compare
BWI76_RS09530 -3.0 -1.5 hypothetical protein compare
BWI76_RS22755 -2.9 -6.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS04680 -2.9 -11.9 2-isopropylmalate synthase compare
BWI76_RS00980 -2.9 -9.9 PLP-dependent threonine dehydratase compare
BWI76_RS04240 -2.9 -3.0 thr operon leader peptide compare
BWI76_RS20360 -2.9 -1.7 cell division protein DedD compare
BWI76_RS09910 -2.8 -13.0 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS20435 -2.8 -1.3 chorismate synthase compare
BWI76_RS22760 -2.7 -8.2 sulfite reductase subunit beta compare
BWI76_RS21465 -2.6 -5.0 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS01800 -2.6 -4.5 glucose-6-phosphate isomerase compare
BWI76_RS08520 -2.6 -2.2 colicin transporter TolQ compare
BWI76_RS05200 -2.6 -2.9 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS20380 -2.5 -1.2 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS11850 -2.5 -6.3 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS26000 -2.5 -8.6 aspartate aminotransferase family protein compare
BWI76_RS07065 -2.5 -5.8 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS25645 -2.4 -6.0 shikimate dehydrogenase compare
BWI76_RS04510 -2.2 -2.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS01350 -2.2 -1.3 NAD(P)H-flavin reductase compare
BWI76_RS17720 -2.2 -1.1 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS00985 -2.2 -6.2 transcriptional regulator IlvY compare
BWI76_RS25315 -2.2 -8.8 glutamate synthase large subunit compare
BWI76_RS24885 -2.1 -2.0 PTS galactitol transporter subunit IIB compare
BWI76_RS25320 -2.1 -4.9 glutamate synthase compare
BWI76_RS21140 -2.1 -2.2 molecular chaperone HscA compare
BWI76_RS04715 -2.0 -1.4 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS21980 -2.0 -2.7 hypothetical protein compare
BWI76_RS08385 -1.9 -3.1 citrate (Si)-synthase compare
BWI76_RS02735 -1.8 -3.0 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS26095 -1.8 -1.5 shikimate kinase compare
BWI76_RS15830 -1.8 -2.7 hypothetical protein compare
BWI76_RS22805 -1.8 -5.2 GTP diphosphokinase compare
BWI76_RS07785 -1.7 -1.1 transcriptional regulator compare
BWI76_RS10990 -1.7 -2.1 dihydroorotase compare
BWI76_RS12335 -1.7 -4.0 hypothetical protein compare
BWI76_RS15825 -1.7 -1.4 hypothetical protein compare
BWI76_RS16275 -1.6 -1.3 fumarate hydratase FumA compare
BWI76_RS11440 -1.6 -1.4 hypothetical protein compare
BWI76_RS05015 -1.6 -1.6 transcriptional regulator compare
BWI76_RS15810 -1.6 -3.9 hypothetical protein compare
BWI76_RS11250 -1.5 -1.5 spermidine/putrescine ABC transporter permease PotB compare
BWI76_RS27940 -1.5 -3.0 2-dehydro-3-deoxy-6-phosphogalactonate aldolase compare
BWI76_RS22640 -1.5 -2.2 hypothetical protein compare
BWI76_RS26620 -1.5 -1.1 Fe-S biogenesis protein NfuA compare
BWI76_RS16240 -1.5 -1.7 anti-adapter protein IraM compare
BWI76_RS00965 -1.5 -1.1 acetolactate synthase 2 small subunit compare
BWI76_RS23520 -1.5 -1.7 hypothetical protein compare
BWI76_RS20640 -1.5 -3.4 cysteine synthase A compare
BWI76_RS22485 -1.4 -3.2 hypothetical protein compare
BWI76_RS13050 -1.4 -2.1 transcriptional regulator compare
BWI76_RS26055 -1.4 -5.3 siroheme synthase compare
BWI76_RS13820 -1.4 -1.8 hypothetical protein compare
BWI76_RS00180 -1.4 -1.2 F0F1 ATP synthase subunit epsilon compare
BWI76_RS15835 -1.4 -1.2 hypothetical protein compare
BWI76_RS12985 -1.4 -1.7 transcriptional regulator compare
BWI76_RS14320 -1.4 -2.0 hypothetical protein compare
BWI76_RS00400 -1.4 -0.8 glutamine synthetase compare
BWI76_RS18240 -1.4 -1.7 L-arabinose ABC transporter permease AraH compare
BWI76_RS21075 -1.4 -1.8 membrane protein compare
BWI76_RS16920 -1.4 -1.7 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS15000 -1.4 -3.1 amino acid ABC transporter ATP-binding protein compare
BWI76_RS21375 -1.4 -1.8 autonomous glycyl radical cofactor GrcA compare
BWI76_RS14450 -1.3 -3.1 hypothetical protein compare
BWI76_RS10465 -1.3 -1.9 hypothetical protein compare
BWI76_RS14650 -1.3 -2.8 helix-turn-helix transcriptional regulator compare
BWI76_RS00960 -1.3 -3.3 acetolactate synthase 2 catalytic subunit compare
BWI76_RS24900 -1.3 -1.5 DeoR family transcriptional regulator compare
BWI76_RS27390 -1.2 -1.8 ribonuclease PH compare
BWI76_RS11580 -1.2 -1.4 L-asparaginase 1 compare
BWI76_RS08580 -1.2 -2.4 quinolinate synthetase compare
BWI76_RS21480 -1.2 -2.9 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS03660 -1.2 -2.8 hypothetical protein compare
BWI76_RS14065 -1.2 -1.6 hypothetical protein compare
BWI76_RS17190 -1.2 -2.3 TonB system transport protein TonB compare
BWI76_RS16220 -1.1 -1.5 hypothetical protein compare
BWI76_RS14415 -1.1 -1.5 transcriptional regulator, TetR family protein compare
BWI76_RS09255 -1.1 -1.2 hypothetical protein compare
BWI76_RS01995 -1.1 -1.2 AraC family transcriptional regulator compare
BWI76_RS18455 -1.1 -1.1 tRNA-Ser compare
BWI76_RS27875 -1.1 -1.3 membrane protein compare
BWI76_RS13980 -1.1 -1.3 hypothetical protein compare
BWI76_RS01170 -1.1 -2.0 uroporphyrinogen-III C-methyltransferase compare
BWI76_RS01275 -1.0 -3.6 LysR family transcriptional regulator compare
BWI76_RS18165 -1.0 -1.1 NUDIX pyrophosphatase compare
BWI76_RS21580 -1.0 -1.2 SsrA-binding protein compare
BWI76_RS18855 -1.0 -1.7 cysteine desulfurase NifS compare
BWI76_RS09190 -1.0 -1.9 hypothetical protein compare
BWI76_RS25280 -1.0 -1.5 RNase adaptor protein RapZ compare
BWI76_RS11040 -1.0 -2.9 ribonuclease E compare
BWI76_RS10510 -1.0 -1.6 OHCU decarboxylase compare
BWI76_RS24925 -1.0 -1.6 DnaA initiator-associating protein DiaA compare
BWI76_RS23240 -1.0 -0.7 exonuclease V subunit gamma compare
BWI76_RS14240 -1.0 -1.9 thiol reductase thioredoxin compare
BWI76_RS12195 -1.0 -1.9 hypothetical protein compare
BWI76_RS12090 -1.0 -0.7 HNH endonuclease compare
BWI76_RS17980 -1.0 -2.6 RNA chaperone ProQ compare
BWI76_RS07115 -1.0 -2.6 hypothetical protein compare
BWI76_RS24330 -1.0 -1.8 TIGR00156 family protein compare
BWI76_RS17975 -1.0 -2.5 tail-specific protease compare
BWI76_RS16950 -1.0 -2.0 TetR family transcriptional regulator compare
BWI76_RS08110 -0.9 -1.8 glutamate/aspartate ABC transporter substrate-binding protein compare
BWI76_RS09195 -0.9 -1.3 N-acetyltransferase compare
BWI76_RS05450 -0.9 -0.7 ribonuclease HI compare
BWI76_RS08620 -0.9 -3.1 galactose-1-phosphate uridylyltransferase compare
BWI76_RS20440 -0.9 -1.1 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS20490 -0.9 -1.2 hypothetical protein compare
BWI76_RS16690 -0.9 -3.3 peptide ABC transporter permease compare
BWI76_RS14805 -0.9 -2.1 hypothetical protein compare
BWI76_RS21690 -0.9 -1.3 hypothetical protein compare
BWI76_RS07185 -0.9 -1.1 hypothetical protein compare
BWI76_RS03045 -0.9 -0.9 hypothetical protein compare
BWI76_RS15350 -0.9 -1.0 hypothetical protein compare
BWI76_RS18770 -0.9 -0.8 DNA gyrase inhibitor compare
BWI76_RS07465 -0.9 -1.2 TetR family transcriptional regulator compare
BWI76_RS17110 -0.9 -1.3 vitamin B12 ABC transporter permease BtuC compare
BWI76_RS15060 -0.9 -1.8 MarR family transcriptional regulator compare
BWI76_RS24080 -0.8 -0.9 DUF179 domain-containing protein compare
BWI76_RS01545 -0.8 -1.4 thiamine biosynthesis protein ThiS compare
BWI76_RS15850 -0.8 -0.8 DUF1317 domain-containing protein compare
BWI76_RS15840 -0.8 -1.9 prophage protein compare
BWI76_RS16605 -0.8 -2.6 hypothetical protein compare
BWI76_RS18385 -0.8 -1.0 hypothetical protein compare
BWI76_RS10745 -0.8 -0.8 hypothetical protein compare
BWI76_RS22125 -0.8 -1.4 membrane protein compare
BWI76_RS23480 -0.8 -4.0 EAL domain-containing protein compare
BWI76_RS21795 -0.8 -1.1 EAL domain-containing protein compare
BWI76_RS25485 -0.8 -1.1 septum formation protein Maf compare
BWI76_RS14325 -0.8 -1.3 maturase compare
BWI76_RS02610 -0.8 -3.0 transcriptional regulator compare
BWI76_RS19460 -0.8 -0.8 lipoprotein compare
BWI76_RS11435 -0.8 -1.1 hypothetical protein compare
BWI76_RS15410 -0.8 -2.5 N-acetyltransferase compare
BWI76_RS16895 -0.8 -1.0 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS01325 -0.8 -1.3 twin-arginine translocase subunit TatB compare
BWI76_RS19900 -0.8 -1.9 FAD:protein FMN transferase compare
BWI76_RS05075 -0.8 -0.7 type II secretion system protein GspG compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in stress experiments

For stress Betaine across organisms