Experiment set17IT009 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_1percent_glucose with Betaine 100 uM

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS21245 +1.5 5.3 nitrogen regulatory protein P-II compare
BWI76_RS16675 +1.5 1.4 ABC transporter compare
BWI76_RS08315 +1.4 3.1 K+-transporting ATPase subunit B compare
BWI76_RS13480 +1.3 2.5 XRE family transcriptional regulator compare
BWI76_RS15845 +1.3 1.5 hypothetical protein compare
BWI76_RS10035 +1.3 2.4 hypothetical protein compare
BWI76_RS26665 +1.2 3.8 DNA-binding response regulator compare
BWI76_RS16805 +1.2 2.9 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS04955 +1.2 2.1 hypoxanthine phosphoribosyltransferase compare
BWI76_RS07765 +1.2 3.3 thioesterase compare
BWI76_RS20750 +1.1 1.5 carboxysome structural protein EutK compare
BWI76_RS25600 +1.1 1.2 tRNA-Thr compare
BWI76_RS25300 +1.1 3.6 hybrid sensor histidine kinase/response regulator compare
BWI76_RS09515 +1.0 3.3 arginine ABC transporter substrate-binding protein compare
BWI76_RS20930 +1.0 2.0 arsenate reductase (glutaredoxin) compare
BWI76_RS21235 +1.0 1.6 hypothetical protein compare
BWI76_RS26440 +1.0 1.8 hypothetical protein compare
BWI76_RS17045 +1.0 1.6 hypothetical protein compare
BWI76_RS12145 +1.0 1.3 hypothetical protein compare
BWI76_RS07740 +1.0 1.9 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS11700 +1.0 1.2 hypothetical protein compare
BWI76_RS15035 +1.0 1.1 metal ABC transporter permease compare
BWI76_RS17915 +0.9 4.4 membrane protein compare
BWI76_RS14770 +0.9 1.5 PTS IIA 2 domain protein compare
BWI76_RS11810 +0.9 2.3 outer membrane protein OmpW compare
BWI76_RS16075 +0.9 1.6 oxidoreductase compare
BWI76_RS17155 +0.9 1.5 hypothetical protein compare
BWI76_RS08820 +0.9 3.6 molybdenum cofactor biosynthesis protein compare
BWI76_RS20565 +0.9 2.0 hypothetical protein compare
BWI76_RS15095 +0.9 2.2 isochorismatase compare
BWI76_RS23140 +0.9 2.5 carboxysome shell protein compare
BWI76_RS16315 +0.9 1.7 SirA-like protein compare
BWI76_RS01905 +0.9 1.2 envelope stress response protein PspG compare
BWI76_RS02220 +0.9 2.9 carbon-phosphorus lyase subunit PhnH compare
BWI76_RS19465 +0.9 2.0 hypothetical protein compare
BWI76_RS23735 +0.9 2.0 sugar diacid utilization regulator compare
BWI76_RS24720 +0.9 1.0 hypothetical protein compare
BWI76_RS00025 +0.8 1.0 hypothetical protein compare
BWI76_RS11150 +0.8 1.4 membrane protein compare
BWI76_RS23580 +0.8 1.7 hypothetical protein compare
BWI76_RS11255 +0.8 1.1 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS09025 +0.8 2.1 GntR family transcriptional regulator compare
BWI76_RS12735 +0.8 2.4 phage repressor protein compare
BWI76_RS21410 +0.8 3.4 lipoprotein compare
BWI76_RS27780 +0.8 1.2 hypothetical protein compare
BWI76_RS15955 +0.8 1.8 transcriptional regulator compare
BWI76_RS16965 +0.8 1.4 murein lipoprotein compare
BWI76_RS13135 +0.8 2.6 3-oxoadipyl-CoA thiolase compare
BWI76_RS09640 +0.8 1.6 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS16205 +0.8 3.9 NAD(P) transhydrogenase subunit alpha compare
BWI76_RS18810 +0.8 3.0 nitrogenase iron protein compare
BWI76_RS10730 +0.8 1.2 bifunctional glucose-1-phosphatase/inositol phosphatase compare
BWI76_RS21345 +0.8 1.3 sigma-E factor regulatory protein RseB compare
BWI76_RS01930 +0.8 2.0 acid phosphatase/phosphotransferase compare
BWI76_RS02815 +0.8 1.3 fructose-bisphosphatase class I compare
BWI76_RS02825 +0.8 1.9 putative acyltransferase domain protein compare
BWI76_RS09305 +0.8 2.0 hypothetical protein compare
BWI76_RS16210 +0.8 1.0 hypothetical protein compare
BWI76_RS21710 +0.7 2.7 nitroreductase compare
BWI76_RS18755 +0.7 0.9 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS06540 +0.7 2.6 DNA-binding protein HU-beta compare
BWI76_RS19860 +0.7 3.2 hypothetical protein compare
BWI76_RS22090 +0.7 2.1 transcriptional regulator compare
BWI76_RS00715 +0.7 1.8 two-component sensor histidine kinase compare
BWI76_RS14625 +0.7 1.0 protein TolA compare
BWI76_RS21200 +0.7 1.9 aldose epimerase compare
BWI76_RS19550 +0.7 3.0 phospho-cellobiase compare
BWI76_RS22935 +0.7 1.6 L-fucose mutarotase compare
BWI76_RS03025 +0.7 2.4 N-acetyltransferase compare
BWI76_RS01285 +0.7 2.7 amino acid ABC transporter substrate-binding protein compare
BWI76_RS24945 +0.7 0.9 glutamine amidotransferase compare
BWI76_RS09555 +0.7 2.0 pyruvate oxidase compare
BWI76_RS12470 +0.7 1.2 thiosulfate sulfurtransferase PspE compare
BWI76_RS14670 +0.7 1.5 hypothetical protein compare
BWI76_RS02745 +0.7 1.2 hypothetical protein compare
BWI76_RS25285 +0.7 1.0 HPr family phosphocarrier protein compare
BWI76_RS01065 +0.7 1.9 ATP-dependent RNA helicase RhlB compare
BWI76_RS27760 +0.7 2.0 lactam utilization protein LamB compare
BWI76_RS01780 +0.7 3.8 SPFH domain / Band 7 family protein compare
BWI76_RS08210 +0.7 1.5 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS09725 +0.7 2.0 MurR/RpiR family transcriptional regulator compare
BWI76_RS21910 +0.7 2.8 glyoxylate/hydroxypyruvate reductase A compare
BWI76_RS05490 +0.7 1.3 Na(+)-translocating NADH-quinone reductase subunit A compare
BWI76_RS07255 +0.7 1.0 hypothetical protein compare
BWI76_RS15740 +0.7 0.8 HNH endonuclease compare
BWI76_RS22430 +0.7 2.1 manganese/iron transporter ATP-binding protein compare
BWI76_RS06740 +0.7 2.7 50S ribosomal protein L36 compare
BWI76_RS16390 +0.7 3.0 dipeptide/tripeptide permease A compare
BWI76_RS08595 +0.7 1.9 hypothetical protein compare
BWI76_RS11235 +0.7 0.9 hypothetical protein compare
BWI76_RS11825 +0.6 2.4 LysR family transcriptional regulator compare
BWI76_RS16680 +0.6 1.5 ABC transporter substrate-binding protein compare
BWI76_RS13380 +0.6 1.6 hypothetical protein compare
BWI76_RS13325 +0.6 2.3 dicarboxylate transporter/tellurite-resistance protein TehA compare
BWI76_RS22820 +0.6 2.2 glycerate kinase compare
BWI76_RS16795 +0.6 1.8 amino acid ABC transporter ATPase compare
BWI76_RS21445 +0.6 1.3 hypothetical protein compare
BWI76_RS06075 +0.6 1.6 taurine transporter subunit compare
BWI76_RS21290 +0.6 2.2 DNA-binding transcriptional regulator compare
BWI76_RS18175 +0.6 2.2 hydrolase compare
BWI76_RS19980 +0.6 1.1 2-keto-3-deoxy-L-rhamnonate aldolase compare
BWI76_RS14850 +0.6 2.6 LacI family transcriptional regulator compare
BWI76_RS01105 +0.6 2.5 glucose-1-phosphate thymidylyltransferase compare
BWI76_RS15900 +0.6 1.1 hypothetical protein compare
BWI76_RS08310 +0.6 1.5 potassium-transporting ATPase subunit C compare
BWI76_RS15790 +0.6 1.9 replication protein compare
BWI76_RS21010 +0.6 1.8 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
BWI76_RS19140 +0.6 3.0 citrate (Si)-synthase compare
BWI76_RS08320 +0.6 3.5 potassium-transporting ATPase subunit KdpA compare
BWI76_RS05880 +0.6 0.7 AraC-type DNA-binding domain-containing protein compare
BWI76_RS24465 +0.6 4.0 adenylate cyclase compare
BWI76_RS19710 +0.6 1.1 NupC/NupG family nucleoside CNT transporter compare
BWI76_RS20610 +0.6 3.0 LysR family transcriptional regulator compare
BWI76_RS16320 +0.6 2.2 methionine ABC transporter substrate-binding protein compare
BWI76_RS11680 +0.6 1.9 succinylglutamate-semialdehyde dehydrogenase compare
BWI76_RS09960 +0.6 1.6 Lon protease compare
BWI76_RS05810 +0.6 0.9 hypothetical protein compare
BWI76_RS23690 +0.6 1.4 putative glyoxalase/bleomycin resistance protein/dioxygenase compare
BWI76_RS15290 +0.6 1.0 transcriptional regulator compare
BWI76_RS27430 +0.6 0.9 (p)ppGpp synthetase compare
BWI76_RS11035 +0.6 1.6 putative LysR-family transcriptional regulator compare
BWI76_RS05885 +0.6 2.3 anion permease compare
BWI76_RS13685 +0.6 0.5 IclR family transcriptional regulator compare
BWI76_RS13250 +0.6 0.8 cytochrome b561 compare
BWI76_RS17910 +0.6 2.0 hypothetical protein compare
BWI76_RS10635 +0.6 1.7 GGDEF domain-containing protein compare
BWI76_RS22205 +0.6 2.0 cation ABC transporter ATP-binding protein compare
BWI76_RS19370 +0.6 1.7 fructose-bisphosphate aldolase compare
BWI76_RS21170 +0.6 2.8 tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ compare
BWI76_RS08360 +0.6 1.1 LamB/YcsF family protein compare
BWI76_RS06135 +0.6 2.6 MFS transporter compare
BWI76_RS14390 +0.6 1.0 hypothetical protein compare
BWI76_RS13960 +0.6 1.9 urea ABC transporter periplasmic protein compare
BWI76_RS14375 +0.6 1.4 hypothetical protein compare
BWI76_RS01940 +0.6 1.1 hypothetical protein compare
BWI76_RS22880 +0.6 1.9 L-serine ammonia-lyase compare
BWI76_RS13630 +0.6 1.2 ABC transporter compare
BWI76_RS17525 +0.6 1.0 XshC-Cox1-family protein compare
BWI76_RS12490 +0.6 1.8 AbrB family transcriptional regulator compare
BWI76_RS14040 +0.6 1.1 thiaminase compare
BWI76_RS26030 +0.6 1.9 cytosine deaminase compare
BWI76_RS26245 +0.6 1.9 transcriptional regulator compare
BWI76_RS06325 +0.6 1.1 hypothetical protein compare
BWI76_RS16935 +0.6 0.9 shikimate dehydrogenase compare
BWI76_RS09420 +0.6 1.1 hypothetical protein compare
BWI76_RS18550 +0.6 1.2 tRNA-Asn compare
BWI76_RS26330 +0.6 1.8 ABC transporter ATP-binding protein compare
BWI76_RS19210 +0.5 2.3 LuxR family transcriptional regulator compare
BWI76_RS08230 +0.5 1.4 hypothetical protein compare
BWI76_RS24765 +0.5 1.6 membrane protein compare
BWI76_RS15970 +0.5 1.7 carboxypeptidase M32 compare
BWI76_RS16640 +0.5 1.5 threonine transporter compare
BWI76_RS16495 +0.5 1.5 endopeptidase compare
BWI76_RS13095 +0.5 1.1 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS22955 +0.5 1.4 transcriptional regulator GcvA compare
BWI76_RS13330 +0.5 0.9 tellurite resistance methyltransferase TehB compare
BWI76_RS08250 +0.5 1.3 tricarballylate utilization protein B compare
BWI76_RS06815 +0.5 1.3 adenine phosphoribosyltransferase compare
BWI76_RS07790 +0.5 1.2 plasmid stabilization protein compare
BWI76_RS10945 +0.5 1.6 SecY/SecA suppressor protein compare
BWI76_RS05640 +0.5 1.3 GntR family transcriptional regulator compare
BWI76_RS06190 +0.5 1.2 hypothetical protein compare
BWI76_RS02180 +0.5 0.6 hypothetical protein compare
BWI76_RS00560 +0.5 2.0 hypothetical protein compare
BWI76_RS15950 +0.5 0.9 dethiobiotin synthase compare
BWI76_RS11205 +0.5 1.3 transcription-repair coupling factor compare
BWI76_RS20325 +0.5 1.1 histidine/lysine/arginine/ornithine ABC transporter permease HisM compare
BWI76_RS01675 +0.5 1.6 putative cytoplasmic protein compare
BWI76_RS07160 +0.5 1.6 MBL fold hydrolase compare
BWI76_RS24460 +0.5 2.4 bifunctional glutamine synthetase adenylyltransferase/deadenyltransferase compare
BWI76_RS12790 +0.5 0.5 lactate dehydrogenase compare
BWI76_RS09310 +0.5 2.2 hypothetical protein compare
BWI76_RS25385 +0.5 2.4 oxaloacetate decarboxylase subunit alpha compare
BWI76_RS17870 +0.5 1.6 coenzyme A pyrophosphatase compare
BWI76_RS22425 +0.5 1.6 metal ABC transporter substrate-binding protein compare
BWI76_RS19770 +0.5 1.1 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS01870 +0.5 1.2 diacylglycerol kinase compare
BWI76_RS25270 +0.5 1.8 ribosome hibernation promoting factor compare
BWI76_RS22840 +0.5 1.0 transposase compare
BWI76_RS19615 +0.5 1.7 vancomycin high temperature exclusion protein compare
BWI76_RS18740 +0.5 1.9 HPP family protein compare
BWI76_RS05975 +0.5 2.3 ABC transporter ATP-binding protein compare
BWI76_RS26835 +0.5 1.9 hypothetical protein compare
BWI76_RS12625 +0.5 1.5 isoflavone reductase compare
BWI76_RS02090 +0.5 1.1 membrane protein compare
BWI76_RS02880 +0.5 1.4 membrane protein compare
BWI76_RS11920 +0.5 1.8 hypothetical protein compare
BWI76_RS14615 +0.5 0.8 hypothetical protein compare
BWI76_RS14970 +0.5 0.9 pyrroline-5-carboxylate reductase compare
BWI76_RS23050 +0.5 1.0 cobalt-precorrin-3B C(17)-methyltransferase compare
BWI76_RS04530 +0.5 0.6 peptidylprolyl isomerase SurA compare
BWI76_RS26670 +0.5 2.8 two-component sensor histidine kinase compare
BWI76_RS14410 +0.5 0.9 hypothetical protein compare
BWI76_RS22120 +0.5 2.0 glutamate--cysteine ligase compare
BWI76_RS08535 +0.5 0.7 translocation protein TolB compare
BWI76_RS11345 +0.5 1.2 LysR family transcriptional regulator compare
BWI76_RS15185 +0.5 0.7 N-acetyltransferase compare
BWI76_RS26575 +0.5 1.8 universal stress protein B compare
BWI76_RS24715 +0.5 2.6 serine/threonine transporter SstT compare
BWI76_RS21995 +0.5 1.6 transcriptional regulator compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in stress experiments

For stress Betaine across organisms