Experiment set17IT006 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_1percent_glucose with Sodium Chloride 200 mM

200 most important genes:

  gene name fitness t score description  
BWI76_RS05840 -7.3 -5.1 glutamate 5-kinase compare
BWI76_RS04675 -7.2 -8.6 3-isopropylmalate dehydrogenase compare
BWI76_RS23920 -7.0 -4.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS18920 -6.7 -4.2 ATP phosphoribosyltransferase compare
BWI76_RS21475 -6.6 -7.3 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS05835 -6.4 -4.1 gamma-glutamyl-phosphate reductase compare
BWI76_RS00850 -6.4 -9.2 acetylglutamate kinase compare
BWI76_RS00855 -6.4 -11.3 argininosuccinate lyase compare
BWI76_RS00805 -6.3 -5.5 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS23360 -6.3 -3.9 diaminopimelate decarboxylase compare
BWI76_RS04670 -6.3 -12.0 3-isopropylmalate dehydratase large subunit compare
BWI76_RS25115 -6.2 -7.7 argininosuccinate synthase compare
BWI76_RS09755 -5.9 -7.1 phosphoserine transaminase compare
BWI76_RS05015 -5.9 -3.8 transcriptional regulator compare
BWI76_RS02995 -5.8 -5.7 aspartate carbamoyltransferase compare
BWI76_RS04665 -5.8 -21.5 3-isopropylmalate dehydratase small subunit compare
BWI76_RS20355 -5.7 -3.1 colicin V production protein compare
BWI76_RS18955 -5.7 -5.6 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS20965 -5.4 -4.0 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS11840 -5.4 -4.5 tryptophan synthase subunit alpha compare
BWI76_RS00980 -5.3 -11.3 PLP-dependent threonine dehydratase compare
BWI76_RS01655 -5.2 -5.7 homoserine O-succinyltransferase compare
BWI76_RS18930 -5.2 -3.8 histidinol-phosphate transaminase compare
BWI76_RS07070 -5.2 -3.6 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS04255 -5.1 -6.2 threonine synthase compare
BWI76_RS18950 -5.1 -4.6 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS18925 -5.1 -7.1 histidinol dehydrogenase compare
BWI76_RS08385 -5.0 -4.7 citrate (Si)-synthase compare
BWI76_RS04470 -5.0 -8.7 carbamoyl phosphate synthase large subunit compare
BWI76_RS24285 -5.0 -8.0 cystathionine beta-lyase compare
BWI76_RS00845 -5.0 -10.8 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS22690 -5.0 -5.6 adenylyl-sulfate kinase compare
BWI76_RS22755 -4.9 -8.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS11860 -4.9 -8.7 anthranilate synthase component I compare
BWI76_RS20350 -4.8 -3.6 amidophosphoribosyltransferase compare
BWI76_RS00965 -4.8 -1.5 acetolactate synthase 2 small subunit compare
BWI76_RS26085 -4.7 -2.5 3-dehydroquinate synthase compare
BWI76_RS04250 -4.7 -6.5 homoserine kinase compare
BWI76_RS18940 -4.6 -6.0 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS07065 -4.6 -6.3 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS04645 -4.6 -4.7 3-dehydroquinase compare
BWI76_RS00990 -4.5 -11.1 ketol-acid reductoisomerase compare
BWI76_RS00835 -4.5 -10.5 phosphoenolpyruvate carboxylase compare
BWI76_RS11850 -4.5 -11.0 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS25320 -4.4 -11.0 glutamate synthase compare
BWI76_RS00785 -4.4 -5.0 cystathionine gamma-synthase compare
BWI76_RS04160 -4.2 -7.3 phosphoserine phosphatase compare
BWI76_RS04245 -4.2 -13.3 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04685 -4.1 -10.5 putative leucine operon leader peptide compare
BWI76_RS01615 -4.1 -7.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS10990 -4.1 -2.1 dihydroorotase compare
BWI76_RS25645 -4.0 -8.7 shikimate dehydrogenase compare
BWI76_RS09910 -4.0 -15.9 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS09645 -4.0 -1.3 thioredoxin-disulfide reductase compare
BWI76_RS22760 -4.0 -7.7 sulfite reductase subunit beta compare
BWI76_RS04465 -4.0 -4.4 carbamoyl-phosphate synthase small subunit compare
BWI76_RS23365 -4.0 -9.1 LysR family transcriptional regulator compare
BWI76_RS03010 -3.9 -6.2 ornithine carbamoyltransferase compare
BWI76_RS18935 -3.9 -7.1 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS23220 -3.8 -8.2 amino-acid N-acetyltransferase compare
BWI76_RS22765 -3.8 -13.5 sulfite reductase subunit alpha compare
BWI76_RS00975 -3.8 -8.3 dihydroxy-acid dehydratase compare
BWI76_RS27385 -3.7 -6.9 orotate phosphoribosyltransferase compare
BWI76_RS11855 -3.7 -9.7 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS00985 -3.7 -7.1 transcriptional regulator IlvY compare
BWI76_RS21265 -3.7 -9.5 phosphoribosylformylglycinamidine synthase compare
BWI76_RS18605 -3.7 -2.4 oxidoreductase molybdopterin-binding protein compare
BWI76_RS04680 -3.7 -9.0 2-isopropylmalate synthase compare
BWI76_RS20895 -3.7 -4.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS11845 -3.6 -3.5 tryptophan synthase subunit beta compare
BWI76_RS20995 -3.5 -2.8 RNA degradosome polyphosphate kinase compare
BWI76_RS11965 -3.5 -2.8 orotidine-5'-phosphate decarboxylase compare
BWI76_RS25315 -3.4 -10.9 glutamate synthase large subunit compare
BWI76_RS01350 -3.3 -1.5 NAD(P)H-flavin reductase compare
BWI76_RS25335 -3.3 -3.6 stringent starvation protein A compare
BWI76_RS09635 -3.1 -1.9 amino acid ABC transporter ATP-binding protein compare
BWI76_RS20435 -3.0 -1.3 chorismate synthase compare
BWI76_RS09760 -3.0 -1.8 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS04240 -2.9 -3.3 thr operon leader peptide compare
BWI76_RS20380 -2.9 -1.3 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS26000 -2.9 -5.2 aspartate aminotransferase family protein compare
BWI76_RS01610 -2.7 -4.9 phosphoribosylamine--glycine ligase compare
BWI76_RS02735 -2.7 -5.2 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS19690 -2.6 -2.8 LysR family transcriptional regulator compare
BWI76_RS26055 -2.5 -5.7 siroheme synthase compare
BWI76_RS21465 -2.5 -1.8 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS01800 -2.4 -3.1 glucose-6-phosphate isomerase compare
BWI76_RS20440 -2.3 -1.8 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS05450 -2.3 -1.4 ribonuclease HI compare
BWI76_RS04510 -2.3 -2.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS22695 -2.3 -5.0 sulfate adenylyltransferase compare
BWI76_RS20970 -2.2 -1.8 phosphoribosylglycinamide formyltransferase compare
BWI76_RS20640 -2.1 -5.3 cysteine synthase A compare
BWI76_RS11440 -2.1 -1.7 hypothetical protein compare
BWI76_RS27390 -2.1 -3.5 ribonuclease PH compare
BWI76_RS09655 -2.0 -4.2 leucine-responsive regulatory protein compare
BWI76_RS04305 -1.9 -1.4 molecular chaperone DnaJ compare
BWI76_RS14075 -1.8 -1.7 TetR family transcriptional regulator compare
BWI76_RS22485 -1.8 -4.4 hypothetical protein compare
BWI76_RS16200 -1.8 -2.2 NAD(P) transhydrogenase subunit beta compare
BWI76_RS22700 -1.7 -4.0 sulfate adenylyltransferase subunit 2 compare
BWI76_RS09190 -1.7 -2.7 hypothetical protein compare
BWI76_RS01275 -1.6 -6.1 LysR family transcriptional regulator compare
BWI76_RS07985 -1.6 -1.4 fluoride ion transporter CrcB compare
BWI76_RS06485 -1.6 -2.6 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS15215 -1.6 -1.2 N-acetyltransferase compare
BWI76_RS13420 -1.6 -1.7 ABC transporter permease compare
BWI76_RS01200 -1.5 -1.4 diaminopimelate epimerase compare
BWI76_RS00400 -1.5 -0.8 glutamine synthetase compare
BWI76_RS13600 -1.5 -3.8 hypothetical protein compare
BWI76_RS21685 -1.5 -1.6 hypothetical protein compare
BWI76_RS17300 -1.5 -1.1 tRNA-Tyr compare
BWI76_RS01330 -1.4 -2.7 twin-arginine translocase subunit TatC compare
BWI76_RS27430 -1.4 -1.1 (p)ppGpp synthetase compare
BWI76_RS22705 -1.4 -5.9 siroheme synthase compare
BWI76_RS21780 -1.4 -3.1 S-(hydroxymethyl)glutathione synthase compare
BWI76_RS20560 -1.4 -2.4 hypothetical protein compare
BWI76_RS07725 -1.4 -1.2 iron-enterobactin transporter permease compare
BWI76_RS13755 -1.4 -1.5 hypothetical protein compare
BWI76_RS20360 -1.4 -1.3 cell division protein DedD compare
BWI76_RS18455 -1.4 -1.3 tRNA-Ser compare
BWI76_RS00430 -1.3 -3.9 GNAT family N-acetyltransferase compare
BWI76_RS06475 -1.3 -1.7 protoheme IX farnesyltransferase compare
BWI76_RS14170 -1.3 -1.6 hypothetical protein compare
BWI76_RS06185 -1.3 -5.2 shikimate kinase II compare
BWI76_RS05200 -1.3 -1.8 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS05915 -1.3 -2.2 helix-turn-helix transcriptional regulator compare
BWI76_RS21075 -1.3 -1.2 membrane protein compare
BWI76_RS26570 -1.3 -2.0 anion permease compare
BWI76_RS12895 -1.3 -2.4 hypothetical protein compare
BWI76_RS25285 -1.3 -1.1 HPr family phosphocarrier protein compare
BWI76_RS15810 -1.2 -3.7 hypothetical protein compare
BWI76_RS25600 -1.2 -0.8 tRNA-Thr compare
BWI76_RS14410 -1.2 -1.7 hypothetical protein compare
BWI76_RS00960 -1.2 -2.6 acetolactate synthase 2 catalytic subunit compare
BWI76_RS12885 -1.2 -2.5 hypothetical protein compare
BWI76_RS23240 -1.2 -0.8 exonuclease V subunit gamma compare
BWI76_RS16360 -1.2 -1.3 electron transport complex subunit RsxB compare
BWI76_RS25060 -1.2 -2.2 lipoprotein NlpI compare
BWI76_RS10835 -1.2 -1.0 hypothetical protein compare
BWI76_RS10770 -1.1 -2.3 pyrimidine utilization protein C compare
BWI76_RS15115 -1.1 -3.1 MFS transporter compare
BWI76_RS03660 -1.1 -2.5 hypothetical protein compare
BWI76_RS05235 -1.1 -0.7 hypothetical protein compare
BWI76_RS07730 -1.1 -1.4 iron-enterobactin transporter membrane protein compare
BWI76_RS27875 -1.1 -1.1 membrane protein compare
BWI76_RS05070 -1.1 -2.1 type II secretion system protein GspH compare
BWI76_RS21980 -1.1 -2.1 hypothetical protein compare
BWI76_RS21340 -1.1 -2.7 SoxR reducing system protein RseC compare
BWI76_RS21165 -1.1 -1.7 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS08665 -1.1 -3.3 6-phosphogluconolactonase compare
BWI76_RS18440 -1.1 -3.1 GtrA-like protein compare
BWI76_RS21570 -1.1 -2.0 RnfH family protein compare
BWI76_RS20650 -1.1 -0.7 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS15920 -1.1 -1.4 hypothetical protein compare
BWI76_RS25000 -1.0 -1.3 malonate decarboxylase acyl carrier protein compare
BWI76_RS14650 -1.0 -1.2 helix-turn-helix transcriptional regulator compare
BWI76_RS16605 -1.0 -2.7 hypothetical protein compare
BWI76_RS24620 -1.0 -2.5 PadR family transcriptional regulator compare
BWI76_RS12390 -1.0 -1.3 antibiotic biosynthesis monooxygenase compare
BWI76_RS19840 -1.0 -1.1 hypothetical protein compare
BWI76_RS15660 -1.0 -0.9 hypothetical protein compare
BWI76_RS11040 -1.0 -3.1 ribonuclease E compare
BWI76_RS01325 -1.0 -1.2 twin-arginine translocase subunit TatB compare
BWI76_RS13820 -1.0 -1.2 hypothetical protein compare
BWI76_RS11285 -1.0 -1.6 transcriptional regulator compare
BWI76_RS08705 -1.0 -2.6 putative LuxR family regulatory protein compare
BWI76_RS25280 -1.0 -1.5 RNase adaptor protein RapZ compare
BWI76_RS24080 -0.9 -1.6 DUF179 domain-containing protein compare
BWI76_RS17980 -0.9 -1.7 RNA chaperone ProQ compare
BWI76_RS06525 -0.9 -3.0 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS26095 -0.9 -0.6 shikimate kinase compare
BWI76_RS10745 -0.9 -0.9 hypothetical protein compare
BWI76_RS13785 -0.9 -1.5 ABC transporter permease compare
BWI76_RS02810 -0.9 -1.9 sugar ABC transporter permease YjfF compare
BWI76_RS18140 -0.9 -2.8 zinc ABC transporter permease compare
BWI76_RS12195 -0.9 -1.4 hypothetical protein compare
BWI76_RS09615 -0.9 -1.7 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS15830 -0.9 -2.4 hypothetical protein compare
BWI76_RS23480 -0.9 -4.7 EAL domain-containing protein compare
BWI76_RS18190 -0.9 -1.4 carboxy-S-adenosyl-L-methionine synthase CmoA compare
BWI76_RS14310 -0.9 -2.8 hypothetical protein compare
BWI76_RS16370 -0.9 -2.6 electron transport complex subunit D compare
BWI76_RS17400 -0.9 -1.1 transporter compare
BWI76_RS16805 -0.9 -1.3 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS09195 -0.9 -1.3 N-acetyltransferase compare
BWI76_RS09690 -0.9 -2.2 dimethyl sulfoxide reductase compare
BWI76_RS00180 -0.8 -0.7 F0F1 ATP synthase subunit epsilon compare
BWI76_RS10955 -0.8 -1.6 hypothetical protein compare
BWI76_RS16375 -0.8 -1.7 electron transport complex subunit G compare
BWI76_RS05520 -0.8 -1.7 hypothetical protein compare
BWI76_RS13495 -0.8 -0.8 hypothetical protein compare
BWI76_RS26175 -0.8 -1.7 DeoR/GlpR family transcriptional regulator compare
BWI76_RS09610 -0.8 -1.8 ATP-dependent Clp protease adaptor ClpS compare
BWI76_RS19025 -0.8 -4.1 phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) compare
BWI76_RS20490 -0.8 -1.4 hypothetical protein compare
BWI76_RS15260 -0.8 -1.1 hypothetical protein compare
BWI76_RS17975 -0.8 -2.4 tail-specific protease compare
BWI76_RS20700 -0.8 -2.6 sulfate/thiosulfate transporter subunit compare
BWI76_RS08545 -0.8 -1.5 cell division protein CpoB compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in stress experiments

For stress Sodium Chloride across organisms