Experiment set16IT062 for Pseudomonas stutzeri RCH2

Compare to:

Lactate-nitrate; anaerobic; copper stress sample3

200 most detrimental genes:

  gene name fitness t score description  
Psest_3937 +2.1 2.2 ATP-dependent protease HslVU, ATPase subunit compare
Psest_0511 +2.1 3.1 rRNA large subunit m3Psi methyltransferase RlmH compare
Psest_1601 +1.9 2.4 Signal transduction histidine kinase compare
Psest_0740 +1.9 2.4 Transcriptional regulator compare
Psest_0725 +1.7 1.6 Negative regulator of beta-lactamase expression compare
Psest_0209 +1.7 3.2 membrane protein AbrB duplication compare
Psest_2899 +1.6 2.2 hypothetical protein compare
Psest_3013 +1.5 2.7 cobyrinic acid a,c-diamide synthase compare
Psest_2855 +1.5 1.9 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Psest_4274 +1.5 4.3 hypothetical protein compare
Psest_2240 +1.4 2.0 hypothetical protein compare
Psest_2907 +1.4 1.5 Protein of unknown function (DUF3618). compare
Psest_3502 +1.4 1.9 flavoprotein, HI0933 family/uncharacterized flavoprotein, PP_4765 family compare
Psest_4170 +1.4 1.1 Flagellar biosynthesis/type III secretory pathway protein compare
Psest_3437 +1.4 3.3 diguanylate cyclase (GGDEF) domain compare
Psest_0999 +1.3 2.4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_2359 +1.3 3.3 Predicted permeases compare
Psest_4307 +1.3 2.2 ABC-type Zn2+ transport system, periplasmic component/surface adhesin compare
Psest_3904 +1.3 1.4 hypothetical protein compare
Psest_2773 +1.2 6.4 glycerol kinase compare
Psest_4273 +1.2 6.8 Lysophospholipase compare
Psest_2457 +1.2 3.0 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) compare
Psest_1053 +1.2 2.2 hypothetical protein compare
Psest_2532 +1.2 2.9 Uncharacterized protein conserved in bacteria compare
Psest_2454 +1.2 1.3 Rhodanese-related sulfurtransferase compare
Psest_3693 +1.2 1.6 Glycosyltransferases involved in cell wall biogenesis compare
Psest_0765 +1.2 4.2 hypothetical protein compare
Psest_1540 +1.2 1.4 biotin-dependent carboxylase uncharacterized domain compare
Psest_0066 +1.2 2.2 Protein of unknown function (DUF3060). compare
Psest_2278 +1.2 1.2 coenzyme PQQ biosynthesis protein PqqD compare
Psest_2238 +1.1 2.5 hypothetical protein compare
Psest_3190 +1.1 5.1 pyruvate kinase compare
Psest_4335 +1.1 3.7 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems compare
Psest_3148 +1.1 1.2 hypothetical protein compare
Psest_3306 +1.1 3.1 conserved hypothetical integral membrane protein compare
Psest_2527 +1.1 5.8 cytochrome c oxidase, cbb3-type, subunit I compare
Psest_2531 +1.0 7.7 cytochrome c oxidase accessory protein FixG compare
Psest_3395 +1.0 1.2 hypothetical protein compare
Psest_3178 +1.0 1.7 formyltetrahydrofolate deformylase compare
Psest_1774 +1.0 1.2 Glutathione peroxidase compare
Psest_0744 +1.0 1.1 Uncharacterized conserved protein compare
Psest_0368 +1.0 2.4 Transcriptional regulator compare
Psest_3088 +1.0 1.9 Protein of unknown function (DUF2905). compare
Psest_3474 +1.0 1.7 Short-chain dehydrogenases of various substrate specificities compare
Psest_3816 +1.0 0.8 DNA-directed RNA polymerase, omega subunit compare
Psest_3355 +1.0 2.6 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components (from data) compare
Psest_0457 +1.0 3.3 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_0260 +1.0 0.7 Cell division protein compare
Psest_0191 +1.0 0.7 PAS domain S-box compare
Psest_1792 +1.0 2.8 RND family efflux transporter, MFP subunit compare
Psest_3100 +0.9 4.3 RNA polymerase sigma factor RpoE compare
Psest_2530 +0.9 4.2 cytochrome c oxidase, cbb3-type, subunit III compare
Psest_1305 +0.9 1.4 Heat shock protein compare
Psest_2061 +0.9 1.7 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Psest_1704 +0.9 1.0 Dehydrogenases (flavoproteins) compare
Psest_0702 +0.9 3.2 Methyl-accepting chemotaxis protein compare
Psest_3902 +0.9 1.7 hypothetical protein compare
Psest_1763 +0.9 1.1 hypothetical protein compare
Psest_3247 +0.9 0.9 Uncharacterized membrane protein compare
Psest_4183 +0.9 2.0 PilZ domain. compare
Psest_1562 +0.9 1.5 Uncharacterized protein conserved in bacteria compare
Psest_3039 +0.9 0.8 periplasmic nitrate reductase, NapE protein compare
Psest_2229 +0.8 2.0 Uncharacterized protein conserved in bacteria compare
Psest_1622 +0.8 1.9 hypothetical protein compare
Psest_3878 +0.8 1.6 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_2525 +0.8 2.4 cytochrome c oxidase, cbb3-type, subunit II compare
Psest_1029 +0.8 2.1 Regulator of competence-specific genes compare
Psest_0551 +0.8 2.3 PEP phosphonomutase and related enzymes compare
Psest_2051 +0.8 3.2 Ribonuclease D compare
Psest_3367 +0.8 1.2 translation initation factor SUI1, putative, prokaryotic compare
Psest_2039 +0.8 2.4 PQQ-dependent catabolism-associated CXXCW motif protein compare
Psest_3790 +0.8 5.4 Cytochrome c5 compare
Psest_2165 +0.8 1.9 Cytochrome B561 compare
Psest_3216 +0.8 7.4 diguanylate cyclase (GGDEF) domain compare
Psest_2148 +0.8 1.8 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_2634 +0.8 3.0 glycine betaine aldehyde dehydrogenase compare
Psest_0791 +0.8 1.8 Acyl-CoA dehydrogenases compare
Psest_2981 +0.8 1.4 sodium pump decarboxylases, gamma subunit compare
Psest_3305 +0.8 4.3 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_0503 +0.8 1.4 Acyl dehydratase compare
Psest_1980 +0.8 1.6 Uncharacterized conserved protein compare
Psest_0833 +0.8 2.1 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains compare
Psest_2743 +0.8 1.6 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Psest_3692 +0.8 1.3 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases compare
Psest_1665 +0.8 1.7 hypothetical protein compare
Psest_1854 +0.8 2.9 Domain of Unknown Function (DUF748). compare
Psest_2413 +0.7 3.1 Periplasmic protein TonB, links inner and outer membranes compare
Psest_3122 +0.7 1.9 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Psest_0325 +0.7 6.2 Putative threonine efflux protein compare
Psest_3850 +0.7 0.5 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_1489 +0.7 1.5 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases compare
Psest_4149 +0.7 2.1 fagellar hook-basal body proteins compare
Psest_1864 +0.7 1.9 diguanylate cyclase (GGDEF) domain compare
Psest_3983 +0.7 1.9 Aldo/keto reductases, related to diketogulonate reductase compare
Psest_4054 +0.7 2.2 alkanesulfonate monooxygenase, FMNH(2)-dependent compare
Psest_0708 +0.7 1.4 outer membrane assembly lipoprotein YfiO compare
Psest_0538 +0.7 6.9 Signal transduction histidine kinase compare
Psest_3389 +0.7 1.4 hypothetical protein compare
Psest_3883 +0.7 3.0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0654 +0.7 2.7 Methylase of chemotaxis methyl-accepting proteins compare
Psest_4158 +0.7 1.4 Flagellar motor protein compare
Psest_0298 +0.7 1.8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0950 +0.7 1.6 hypothetical protein compare
Psest_2749 +0.7 1.5 Predicted transcriptional regulators compare
Psest_1916 +0.7 2.7 Uncharacterized protein conserved in bacteria compare
Psest_1049 +0.7 1.5 Uncharacterized paraquat-inducible protein A compare
Psest_3343 +0.7 1.4 Predicted periplasmic protein compare
Psest_2405 +0.7 1.8 NAD-dependent protein deacetylases, SIR2 family compare
Psest_1882 +0.7 2.8 Signal transduction histidine kinase compare
Psest_3014 +0.7 0.9 cob(I)alamin adenosyltransferase compare
Psest_1089 +0.7 2.3 ABC-type branched-chain amino acid transport systems, ATPase component compare
Psest_1725 +0.7 5.0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0115 +0.7 0.8 Predicted integral membrane protein compare
Psest_2127 +0.7 2.4 Transcriptional regulator compare
Psest_3803 +0.7 0.8 DNA repair protein radc compare
Psest_2099 +0.7 1.5 nicotinamide mononucleotide transporter PnuC compare
Psest_1881 +0.7 2.6 Nitroreductase compare
Psest_3678 +0.7 2.1 acyl-phosphate glycerol 3-phosphate acyltransferase compare
Psest_1895 +0.7 1.9 Signal transduction histidine kinase compare
Psest_1611 +0.7 1.9 Beta-lactamase class D compare
Psest_4177 +0.7 0.7 flagellar biosynthetic protein FliP compare
Psest_3307 +0.7 4.0 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_1677 +0.7 0.8 Protein-tyrosine-phosphatase compare
Psest_3203 +0.7 1.6 hypothetical protein compare
Psest_0139 +0.6 2.0 ABC-type histidine transport system, ATPase component compare
Psest_3338 +0.6 0.5 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_3204 +0.6 2.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_4217 +0.6 2.7 Rhs element Vgr protein compare
Psest_2545 +0.6 1.4 recombination protein RecR compare
Psest_1804 +0.6 0.7 Superfamily II DNA and RNA helicases compare
Psest_3217 +0.6 6.0 PAS domain S-box compare
Psest_2271 +0.6 0.6 coenzyme PQQ biosynthesis protein PqqD compare
Psest_1946 +0.6 2.1 Protein of unknown function (DUF2835). compare
Psest_2047 +0.6 1.8 Signal transduction histidine kinase compare
Psest_1826 +0.6 1.9 hypothetical protein compare
Psest_0028 +0.6 2.5 Coproporphyrinogen III oxidase compare
Psest_1732 +0.6 1.2 flagellar biosynthetic protein FliP compare
Psest_2561 +0.6 0.6 hypothetical protein compare
Psest_3372 +0.6 3.9 Tfp pilus assembly protein PilW compare
Psest_2448 +0.6 1.6 AraC-type DNA-binding domain-containing proteins compare
Psest_4330 +0.6 1.1 Protein of unknown function (DUF2909). compare
Psest_0504 +0.6 1.7 Putative effector of murein hydrolase LrgA compare
Psest_3002 +0.6 1.1 Putative translation initiation inhibitor, yjgF family compare
Psest_1924 +0.6 5.3 adhesin-associated MmpL efflux pump (from data) compare
Psest_4276 +0.6 1.4 hypothetical protein compare
Psest_2363 +0.6 2.9 hypothetical protein compare
Psest_0198 +0.6 3.7 TRAP transporter solute receptor, TAXI family compare
Psest_0822 +0.6 1.3 Transcriptional regulators compare
Psest_1775 +0.6 1.8 Predicted ATPase (AAA+ superfamily) compare
Psest_0717 +0.6 5.2 Protein of unknown function (DUF1631). compare
Psest_0444 +0.6 2.9 methionine-S-sulfoxide reductase compare
Psest_0527 +0.6 3.1 Uncharacterized conserved protein compare
Psest_2681 +0.6 0.6 Uncharacterized protein conserved in bacteria compare
Psest_0257 +0.6 0.8 Predicted Zn-dependent peptidases compare
Psest_0359 +0.6 1.2 Transcriptional regulators compare
Psest_3336 +0.6 1.6 Membrane proteins related to metalloendopeptidases compare
Psest_0192 +0.6 3.3 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_2000 +0.6 2.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_0311 +0.6 2.6 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_2409 +0.6 2.0 Serine/threonine protein phosphatase compare
Psest_3447 +0.6 0.9 Uncharacterized MobA-related protein compare
Psest_3853 +0.6 1.0 ABC-type branched-chain amino acid transport systems, ATPase component compare
Psest_1026 +0.6 1.8 Uncharacterized iron-regulated protein compare
Psest_2098 +0.6 1.8 Predicted ATPase/kinase involved in NAD metabolism compare
Psest_0773 +0.6 1.7 Cytosine deaminase and related metal-dependent hydrolases compare
Psest_0732 +0.6 1.5 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_1960 +0.6 1.4 Bacterial protein of unknown function (DUF903). compare
Psest_1390 +0.6 1.6 Uncharacterized ABC-type transport system, permease component compare
Psest_0545 +0.6 3.1 urease accessory protein UreG compare
Psest_4008 +0.6 4.5 PAS domain S-box compare
Psest_3554 +0.6 1.3 Uncharacterized protein conserved in bacteria compare
Psest_3371 +0.6 3.2 type IV pilus modification protein PilV compare
Psest_0779 +0.6 1.9 tyrosine aminotransferase (EC 2.6.1.57) (from data) compare
Psest_3191 +0.6 1.3 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases compare
Psest_0095 +0.6 2.4 phosphonate C-P lyase system protein PhnH compare
Psest_1722 +0.6 3.3 flagellar protein export ATPase FliI compare
Psest_1185 +0.6 1.0 heavy metal response regulator compare
Psest_3659 +0.6 1.0 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_1238 +0.6 2.3 Predicted membrane protein/domain compare
Psest_0401 +0.6 0.9 isopentenyl-diphosphate delta-isomerase, type 2 compare
Psest_3270 +0.6 0.9 probable S-adenosylmethionine-dependent methyltransferase, YraL family compare
Psest_2041 +0.6 1.6 ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system compare
Psest_0061 +0.6 0.7 hypothetical protein compare
Psest_0501 +0.5 0.9 Predicted nucleoside-diphosphate-sugar epimerases compare
Psest_2950 +0.5 2.5 putative NAD(P)H quinone oxidoreductase, PIG3 family compare
Psest_0318 +0.5 2.4 NAD-dependent DNA ligase (contains BRCT domain type II) compare
Psest_2022 +0.5 1.0 ADP-ribose pyrophosphatase compare
Psest_2128 +0.5 1.5 Acyl-CoA dehydrogenases compare
Psest_2581 +0.5 1.0 Uncharacterized protein conserved in bacteria compare
Psest_0693 +0.5 4.8 His Kinase A (phosphoacceptor) domain./PAS fold./Response regulator receiver domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. compare
Psest_0563 +0.5 1.6 urea ABC transporter, ATP-binding protein UrtE compare
Psest_1022 +0.5 2.9 Thiol:disulfide interchange protein compare
Psest_4168 +0.5 1.5 Flagellar FliJ protein. compare
Psest_3472 +0.5 3.0 Long-chain acyl-CoA synthetases (AMP-forming) compare
Psest_1516 +0.5 1.1 Uncharacterized lipoprotein compare
Psest_3518 +0.5 0.6 Transcriptional regulators compare
Psest_1719 +0.5 2.3 flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF) compare
Psest_2693 +0.5 1.3 muconolactone delta-isomerase compare
Psest_1147 +0.5 1.2 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_1634 +0.5 2.6 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain compare


Specific Phenotypes

For 6 genes in this experiment

For stress copper (II) chloride dihydrate in Pseudomonas stutzeri RCH2

For stress copper (II) chloride dihydrate across organisms