Experiment set16IT040 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Nitrate reduction, replicate B

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3782 -5.6 -3.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3253 -5.4 -3.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3645 -4.5 -12.9 Type I secretion outer membrane protein, TolC precursor compare
Pf6N2E2_3932 -4.5 -6.8 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_5394 -4.4 -3.7 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_4473 -4.4 -12.2 HlyD family secretion protein compare
Pf6N2E2_5223 -4.3 -6.1 Molybdopterin biosynthesis protein MoeB compare
Pf6N2E2_63 -4.2 -4.8 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_736 -4.2 -5.0 hypothetical protein compare
Pf6N2E2_3842 -4.2 -5.7 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_2323 -4.2 -4.0 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_3807 -4.2 -7.0 Histidine utilization repressor compare
Pf6N2E2_5239 -4.2 -14.2 Putative sulfate permease conserved
Pf6N2E2_732 -4.1 -6.9 Respiratory nitrate reductase gamma chain (EC 1.7.99.4) compare
Pf6N2E2_5392 -4.1 -2.8 Molybdenum cofactor biosynthesis protein MoaC compare
Pf6N2E2_4564 -4.1 -10.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4472 -4.0 -17.3 ABC-type multidrug transport system, permease component compare
Pf6N2E2_3610 -4.0 -6.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4047 -3.9 -4.6 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_735 -3.9 -16.3 Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) conserved
Pf6N2E2_3752 -3.9 -20.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_1294 -3.9 -3.3 Carbon starvation protein A compare
Pf6N2E2_3751 -3.8 -14.6 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_5177 -3.8 -11.7 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_730 -3.8 -10.2 Respiratory nitrate reductase beta chain (EC 1.7.99.4) compare
Pf6N2E2_5666 -3.7 -12.7 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_66 -3.7 -9.4 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_64 -3.7 -2.8 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_5309 -3.6 -8.0 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_4048 -3.6 -8.9 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_477 -3.6 -6.7 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf6N2E2_4825 -3.5 -9.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_2074 -3.5 -2.4 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3252 -3.4 -9.4 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_728 -3.4 -4.6 Nitrate/nitrite transporter compare
Pf6N2E2_77 -3.4 -4.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_729 -3.4 -16.1 Respiratory nitrate reductase alpha chain (EC 1.7.99.4) conserved
Pf6N2E2_726 -3.4 -5.2 Nitrate/nitrite sensor protein (EC 2.7.3.-) compare
Pf6N2E2_4596 -3.4 -10.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4826 -3.3 -9.0 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_2277 -3.3 -3.1 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_723 -3.2 -4.9 FIG138517: Putative lipid carrier protein compare
Pf6N2E2_725 -3.2 -6.7 Nitrate/nitrite response regulator protein compare
Pf6N2E2_1296 -3.2 -7.1 DNA-binding response regulator, LuxR family compare
Pf6N2E2_178 -3.2 -1.6 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_3630 -3.2 -7.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_737 -3.2 -2.2 Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) compare
Pf6N2E2_71 -3.2 -6.7 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_432 -3.1 -7.4 Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1) compare
Pf6N2E2_4372 -3.0 -2.9 FIG00460773: hypothetical protein compare
Pf6N2E2_731 -3.0 -5.4 Respiratory nitrate reductase delta chain (EC 1.7.99.4) compare
Pf6N2E2_5308 -3.0 -13.1 Transcriptional regulator, AraC family compare
Pf6N2E2_3839 -2.9 -5.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4471 -2.9 -8.1 ABC-type multidrug transport system, permease component compare
Pf6N2E2_3264 -2.9 -4.0 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4597 -2.9 -8.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4921 -2.8 -4.6 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) compare
Pf6N2E2_3841 -2.8 -5.8 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_2218 -2.7 -4.5 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_711 -2.7 -8.3 Nitric oxide reductase activation protein NorD conserved
Pf6N2E2_5176 -2.7 -3.7 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_431 -2.7 -7.2 Molybdenum transport system permease protein ModB (TC 3.A.1.8.1) compare
Pf6N2E2_5242 -2.6 -2.5 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2217 -2.6 -3.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_5175 -2.5 -5.4 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_292 -2.5 -10.2 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Pf6N2E2_3255 -2.5 -4.1 YrbA protein compare
Pf6N2E2_722 -2.5 -7.2 FIG139928: Putative protease compare
Pf6N2E2_718 -2.4 -4.7 Pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5) compare
Pf6N2E2_721 -2.4 -7.5 FIG139552: Putative protease compare
Pf6N2E2_1411 -2.3 -7.9 Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) compare
Pf6N2E2_710 -2.2 -9.1 Nitric-oxide reductase subunit B (EC 1.7.99.7) conserved
Pf6N2E2_3248 -2.2 -2.1 Probable transmembrane protein compare
Pf6N2E2_2189 -2.1 -4.5 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_4813 -2.1 -12.8 Probable two-component sensor, near polyamine transporter compare
Pf6N2E2_709 -2.1 -6.2 Nitric-oxide reductase subunit C (EC 1.7.99.7) compare
Pf6N2E2_4612 -2.1 -3.7 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_733 -2.1 -2.6 Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8) compare
Pf6N2E2_4351 -2.1 -10.6 Predicted signal transduction protein compare
Pf6N2E2_3783 -2.1 -5.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3661 -2.1 -2.4 hypothetical protein compare
Pf6N2E2_5728 -2.1 -5.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_5258 -2.1 -8.4 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_2422 -2.1 -8.0 Molybdopterin biosynthesis protein MoeA compare
Pf6N2E2_3346 -2.1 -6.4 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_3074 -2.0 -1.7 FIG00960973: hypothetical protein compare
Pf6N2E2_2507 -2.0 -6.2 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_1293 -1.9 -1.9 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_2424 -1.9 -2.3 Molybdopterin-guanine dinucleotide biosynthesis protein MobA compare
Pf6N2E2_2340 -1.9 -3.4 Transcriptional regulator, GntR family compare
Pf6N2E2_3984 -1.9 -11.0 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_2073 -1.9 -5.9 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_2674 -1.9 -1.2 FIG00953856: hypothetical protein compare
Pf6N2E2_2465 -1.8 -5.1 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3847 -1.8 -2.4 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_706 -1.8 -6.3 Nitric oxide reductase activation protein NorQ compare
Pf6N2E2_760 -1.8 -9.5 Na+/H+ antiporter NhaB compare
Pf6N2E2_2201 -1.8 -3.5 Transmembrane regulator protein PrtR compare
Pf6N2E2_4773 -1.8 -2.1 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_5257 -1.8 -8.1 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_5080 -1.8 -6.4 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family compare
Pf6N2E2_510 -1.8 -9.1 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf6N2E2_3060 -1.7 -3.0 Outer membrane protein H precursor compare
Pf6N2E2_1295 -1.7 -3.9 Sensor histidine kinase compare
Pf6N2E2_1776 -1.7 -1.3 Chemotaxis protein CheD compare
Pf6N2E2_712 -1.7 -3.1 hypothetical protein compare
Pf6N2E2_2825 -1.7 -5.6 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_2513 -1.7 -1.1 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_5328 -1.7 -5.3 FIG00958649: hypothetical protein compare
Pf6N2E2_2508 -1.7 -4.0 hypothetical protein compare
Pf6N2E2_2823 -1.6 -5.4 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_4803 -1.6 -1.1 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_40 -1.6 -3.0 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_707 -1.6 -5.5 Nitric oxide reductase activation protein NorE compare
Pf6N2E2_5679 -1.6 -4.0 hypothetical protein compare
Pf6N2E2_2822 -1.6 -6.4 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_4817 -1.6 -12.3 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
Pf6N2E2_945 -1.6 -2.5 Transcriptional regulator, TetR family compare
Pf6N2E2_4993 -1.6 -2.9 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf6N2E2_3487 -1.6 -7.1 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_5291 -1.6 -11.2 Fumarylacetoacetase (EC 3.7.1.2) compare
Pf6N2E2_2506 -1.5 -8.5 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_4057 -1.5 -0.7 lipoprotein, putative compare
Pf6N2E2_4579 -1.5 -1.0 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_2180 -1.5 -4.9 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_5705 -1.5 -2.1 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_2574 -1.5 -1.4 Flagellar synthesis regulator FleN compare
Pf6N2E2_2510 -1.5 -2.0 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_4273 -1.5 -5.8 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_2588 -1.5 -3.3 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3170 -1.5 -4.2 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2447 -1.5 -4.2 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_2824 -1.5 -8.3 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_5894 -1.5 -6.6 Putative threonine efflux protein compare
Pf6N2E2_3940 -1.4 -7.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3658 -1.4 -4.7 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_1673 -1.4 -2.2 Transcriptional regulator, TetR family compare
Pf6N2E2_1932 -1.4 -2.3 Transcriptional regulator, IclR family compare
Pf6N2E2_1749 -1.4 -2.4 Cyn operon transcriptional activator compare
Pf6N2E2_2509 -1.4 -2.3 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_2753 -1.4 -2.3 HtrA protease/chaperone protein compare
Pf6N2E2_4414 -1.4 -1.2 FIG00953808: hypothetical protein compare
Pf6N2E2_1885 -1.4 -2.8 Transcriptional regulator, AraC family compare
Pf6N2E2_717 -1.3 -4.8 Functional role page for Anaerobic nitric oxide reductase transcription regulator NorR compare
Pf6N2E2_6099 -1.3 -0.9 tRNA-Glu-TTC compare
Pf6N2E2_2188 -1.3 -3.4 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_4187 -1.3 -5.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5049 -1.3 -1.6 acetyltransferase, GNAT family compare
Pf6N2E2_5848 -1.3 -4.2 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf6N2E2_4928 -1.3 -1.3 Permeases of the major facilitator superfamily compare
Pf6N2E2_5072 -1.3 -6.5 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) compare
Pf6N2E2_4276 -1.3 -4.0 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_3300 -1.3 -2.4 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_4607 -1.3 -3.2 Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR compare
Pf6N2E2_4360 -1.3 -7.5 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_5884 -1.3 -7.3 Sensor histidine kinase compare
Pf6N2E2_4749 -1.3 -3.9 DNA polymerase III epsilon subunit (EC 2.7.7.7) compare
Pf6N2E2_3844 -1.2 -1.6 hypothetical protein compare
Pf6N2E2_5743 -1.2 -3.2 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) compare
Pf6N2E2_2384 -1.2 -0.8 CmpX compare
Pf6N2E2_2013 -1.2 -1.8 hypothetical protein compare
Pf6N2E2_1652 -1.2 -2.5 Transcriptional regulator, TetR family compare
Pf6N2E2_5520 -1.2 -4.5 Sensory box histidine kinase compare
Pf6N2E2_4454 -1.2 -4.4 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_5553 -1.2 -5.8 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_2264 -1.2 -1.6 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_1116 -1.2 -1.8 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_2752 -1.2 -1.8 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_2986 -1.2 -2.3 Transcriptional regulator, LuxR family compare
Pf6N2E2_5295 -1.2 -3.9 Serine hydroxymethyltransferase (EC 2.1.2.1) compare
Pf6N2E2_4422 -1.2 -1.8 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
Pf6N2E2_2152 -1.2 -1.1 hypothetical protein compare
Pf6N2E2_3475 -1.2 -1.5 hypothetical protein compare
Pf6N2E2_4638 -1.1 -1.8 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_5030 -1.1 -5.2 Transcriptional regulator, AsnC family compare
Pf6N2E2_4415 -1.1 -2.2 Putative FMN hydrolase (EC 3.1.3.-); 5-Amino-6-(5'-phosphoribitylamino)uracil phosphatase compare
Pf6N2E2_3077 -1.1 -2.5 FIG138056: a glutathione-dependent thiol reductase compare
Pf6N2E2_3183 -1.1 -1.7 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_3039 -1.1 -5.4 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_5014 -1.1 -0.5 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_1534 -1.1 -1.2 Probable transmembrane protein compare
Pf6N2E2_1812 -1.1 -3.0 peptide ABC transporter, ATP-binding protein compare
Pf6N2E2_4097 -1.1 -8.0 FIG00953365: hypothetical protein compare
Pf6N2E2_2564 -1.1 -4.8 Positive regulator of CheA protein activity (CheW) compare
Pf6N2E2_3251 -1.1 -5.9 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_1782 -1.1 -2.4 STAS domain protein compare
Pf6N2E2_3786 -1.1 -5.0 Twin-arginine translocation protein TatC compare
Pf6N2E2_4797 -1.1 -1.7 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_238 -1.1 -1.2 hypothetical protein compare
Pf6N2E2_5723 -1.1 -5.3 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_5157 -1.1 -6.0 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2181 -1.1 -2.4 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_658 -1.1 -6.1 sensor histidine kinase compare
Pf6N2E2_2176 -1.1 -1.3 Amidases related to nicotinamidase compare
Pf6N2E2_2518 -1.1 -1.5 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_204 -1.0 -1.8 hypothetical protein compare
Pf6N2E2_5849 -1.0 -7.3 large component of pyruvate transporter (actP-like) (from data) compare
Pf6N2E2_1315 -1.0 -1.5 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) compare
Pf6N2E2_5646 -1.0 -1.2 PROBABLE MEMBRANE PROTEIN compare
Pf6N2E2_1043 -1.0 -2.2 Transcriptional regulator, IclR family compare


Specific Phenotypes

For 23 genes in this experiment

For denitrifying Sodium pyruvate in Pseudomonas fluorescens FW300-N2E2

For denitrifying Sodium pyruvate across organisms