Experiment set16IT039 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Nitrate reduction, replicate A

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_64 -6.6 -4.5 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3842 -5.9 -4.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_477 -5.5 -7.5 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf6N2E2_3782 -5.1 -4.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3253 -5.0 -4.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_736 -5.0 -4.8 hypothetical protein compare
Pf6N2E2_4825 -5.0 -8.9 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4473 -4.6 -12.0 HlyD family secretion protein compare
Pf6N2E2_4472 -4.6 -17.2 ABC-type multidrug transport system, permease component compare
Pf6N2E2_5239 -4.5 -14.5 Putative sulfate permease conserved
Pf6N2E2_71 -4.5 -7.5 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3839 -4.4 -6.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4564 -4.4 -10.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3751 -4.3 -14.1 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_731 -4.2 -7.0 Respiratory nitrate reductase delta chain (EC 1.7.99.4) compare
Pf6N2E2_2277 -4.2 -2.8 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_3752 -4.1 -21.3 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3610 -4.0 -6.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4826 -3.9 -9.1 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3841 -3.9 -4.6 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_77 -3.9 -4.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3252 -3.6 -9.3 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_725 -3.6 -6.5 Nitrate/nitrite response regulator protein compare
Pf6N2E2_732 -3.6 -7.9 Respiratory nitrate reductase gamma chain (EC 1.7.99.4) compare
Pf6N2E2_4047 -3.6 -4.9 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_730 -3.6 -10.7 Respiratory nitrate reductase beta chain (EC 1.7.99.4) compare
Pf6N2E2_66 -3.5 -10.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_2465 -3.5 -6.2 Cys regulon transcriptional activator CysB compare
Pf6N2E2_729 -3.4 -16.9 Respiratory nitrate reductase alpha chain (EC 1.7.99.4) conserved
Pf6N2E2_5177 -3.4 -11.4 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_735 -3.4 -14.6 Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) conserved
Pf6N2E2_2674 -3.4 -1.7 FIG00953856: hypothetical protein compare
Pf6N2E2_5309 -3.3 -8.3 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_3645 -3.3 -10.7 Type I secretion outer membrane protein, TolC precursor compare
Pf6N2E2_737 -3.3 -2.2 Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) compare
Pf6N2E2_3932 -3.2 -4.6 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4471 -3.2 -7.8 ABC-type multidrug transport system, permease component compare
Pf6N2E2_2217 -3.2 -3.1 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4048 -3.2 -6.7 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_5394 -3.2 -5.6 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_2218 -3.2 -4.3 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_5308 -3.1 -15.2 Transcriptional regulator, AraC family compare
Pf6N2E2_5223 -3.1 -4.4 Molybdopterin biosynthesis protein MoeB compare
Pf6N2E2_1296 -3.1 -7.0 DNA-binding response regulator, LuxR family compare
Pf6N2E2_3300 -3.1 -3.6 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_2323 -3.1 -2.6 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_3630 -3.0 -7.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_722 -3.0 -8.4 FIG139928: Putative protease compare
Pf6N2E2_3264 -2.9 -5.3 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_5176 -2.9 -3.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_726 -2.9 -4.0 Nitrate/nitrite sensor protein (EC 2.7.3.-) compare
Pf6N2E2_2509 -2.8 -2.8 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_4372 -2.8 -3.3 FIG00460773: hypothetical protein compare
Pf6N2E2_5175 -2.8 -4.6 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4596 -2.7 -9.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_728 -2.7 -3.7 Nitrate/nitrite transporter compare
Pf6N2E2_2574 -2.7 -1.8 Flagellar synthesis regulator FleN compare
Pf6N2E2_5666 -2.7 -12.1 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_432 -2.7 -7.6 Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1) compare
Pf6N2E2_63 -2.6 -3.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_1412 -2.6 -3.5 hypothetical protein compare
Pf6N2E2_3255 -2.6 -4.2 YrbA protein compare
Pf6N2E2_718 -2.5 -3.6 Pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5) compare
Pf6N2E2_3661 -2.5 -1.7 hypothetical protein compare
Pf6N2E2_5520 -2.5 -6.4 Sensory box histidine kinase compare
Pf6N2E2_5841 -2.5 -1.2 GlcG protein compare
Pf6N2E2_721 -2.5 -7.2 FIG139552: Putative protease compare
Pf6N2E2_4612 -2.5 -3.7 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_706 -2.5 -7.1 Nitric oxide reductase activation protein NorQ compare
Pf6N2E2_4638 -2.5 -1.7 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_292 -2.4 -9.1 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Pf6N2E2_5728 -2.4 -5.6 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_3807 -2.4 -7.0 Histidine utilization repressor compare
Pf6N2E2_712 -2.4 -2.9 hypothetical protein compare
Pf6N2E2_4597 -2.4 -7.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3783 -2.4 -6.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3183 -2.4 -3.8 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_1411 -2.4 -7.9 Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) compare
Pf6N2E2_709 -2.4 -7.9 Nitric-oxide reductase subunit C (EC 1.7.99.7) compare
Pf6N2E2_2201 -2.3 -4.2 Transmembrane regulator protein PrtR compare
Pf6N2E2_711 -2.3 -8.4 Nitric oxide reductase activation protein NorD conserved
Pf6N2E2_5392 -2.3 -3.4 Molybdenum cofactor biosynthesis protein MoaC compare
Pf6N2E2_3847 -2.3 -2.2 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_2073 -2.2 -6.7 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_2508 -2.2 -4.4 hypothetical protein compare
Pf6N2E2_1294 -2.2 -3.0 Carbon starvation protein A compare
Pf6N2E2_2189 -2.2 -4.1 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_4797 -2.2 -2.5 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_1932 -2.1 -2.5 Transcriptional regulator, IclR family compare
Pf6N2E2_2506 -2.1 -10.4 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_3074 -2.1 -1.7 FIG00960973: hypothetical protein compare
Pf6N2E2_2074 -2.1 -2.1 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3940 -2.1 -9.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5080 -2.0 -8.4 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family compare
Pf6N2E2_4813 -2.0 -11.7 Probable two-component sensor, near polyamine transporter compare
Pf6N2E2_4414 -1.9 -1.3 FIG00953808: hypothetical protein compare
Pf6N2E2_4351 -1.9 -11.3 Predicted signal transduction protein compare
Pf6N2E2_3984 -1.9 -10.4 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4921 -1.9 -4.3 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) compare
Pf6N2E2_710 -1.9 -8.4 Nitric-oxide reductase subunit B (EC 1.7.99.7) conserved
Pf6N2E2_895 -1.9 -3.9 Transcriptional regulator, HxlR family compare
Pf6N2E2_5242 -1.9 -2.4 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2424 -1.9 -2.0 Molybdopterin-guanine dinucleotide biosynthesis protein MobA compare
Pf6N2E2_5679 -1.8 -5.0 hypothetical protein compare
Pf6N2E2_3170 -1.8 -4.6 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_760 -1.8 -11.4 Na+/H+ antiporter NhaB compare
Pf6N2E2_431 -1.7 -5.4 Molybdenum transport system permease protein ModB (TC 3.A.1.8.1) compare
Pf6N2E2_4818 -1.7 -6.0 Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) compare
Pf6N2E2_4817 -1.7 -12.2 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
Pf6N2E2_3346 -1.7 -5.5 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_2422 -1.7 -7.1 Molybdopterin biosynthesis protein MoeA compare
Pf6N2E2_2823 -1.6 -4.4 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_3487 -1.6 -8.0 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_4273 -1.6 -6.5 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_2681 -1.6 -1.0 3-phosphoglycerate kinase compare
Pf6N2E2_2753 -1.6 -2.5 HtrA protease/chaperone protein compare
Pf6N2E2_4579 -1.6 -1.0 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_350 -1.6 -1.7 Gfa-like protein compare
Pf6N2E2_5258 -1.6 -7.3 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_1295 -1.5 -4.1 Sensor histidine kinase compare
Pf6N2E2_2507 -1.5 -5.2 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_5425 -1.5 -1.9 hypothetical protein compare
Pf6N2E2_2062 -1.5 -1.1 FIG00955561: hypothetical protein compare
Pf6N2E2_723 -1.5 -2.0 FIG138517: Putative lipid carrier protein compare
Pf6N2E2_5103 -1.5 -0.9 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_5291 -1.5 -10.3 Fumarylacetoacetase (EC 3.7.1.2) compare
Pf6N2E2_717 -1.5 -5.7 Functional role page for Anaerobic nitric oxide reductase transcription regulator NorR compare
Pf6N2E2_648 -1.5 -2.1 General secretion pathway protein K compare
Pf6N2E2_4187 -1.4 -7.5 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_1749 -1.4 -2.6 Cyn operon transcriptional activator compare
Pf6N2E2_4454 -1.4 -5.0 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_1735 -1.4 -3.1 PhnB protein compare
Pf6N2E2_2340 -1.4 -2.6 Transcriptional regulator, GntR family compare
Pf6N2E2_2225 -1.4 -1.9 FIG00953489: hypothetical protein compare
Pf6N2E2_2018 -1.4 -1.5 hypothetical protein compare
Pf6N2E2_3282 -1.3 -1.8 FIG005080: Possible exported protein compare
Pf6N2E2_733 -1.3 -3.4 Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8) compare
Pf6N2E2_2824 -1.3 -7.9 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_2822 -1.3 -5.6 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_2176 -1.3 -1.8 Amidases related to nicotinamidase compare
Pf6N2E2_1758 -1.3 -1.9 Transcriptional regulator, MarR family compare
Pf6N2E2_510 -1.3 -7.3 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf6N2E2_5328 -1.3 -4.7 FIG00958649: hypothetical protein compare
Pf6N2E2_4276 -1.3 -4.1 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_4607 -1.3 -2.4 Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR compare
Pf6N2E2_5848 -1.3 -3.3 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf6N2E2_2825 -1.3 -4.7 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_2447 -1.3 -4.4 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_4415 -1.3 -2.4 Putative FMN hydrolase (EC 3.1.3.-); 5-Amino-6-(5'-phosphoribitylamino)uracil phosphatase compare
Pf6N2E2_1040 -1.3 -1.1 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_5849 -1.2 -8.6 large component of pyruvate transporter (actP-like) (from data) compare
Pf6N2E2_2186 -1.2 -4.6 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_5257 -1.2 -6.0 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_1652 -1.2 -2.6 Transcriptional regulator, TetR family compare
Pf6N2E2_2794 -1.2 -1.8 putative membrane protein compare
Pf6N2E2_5794 -1.2 -2.3 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_4993 -1.2 -1.9 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf6N2E2_5843 -1.2 -2.1 hypothetical protein compare
Pf6N2E2_5884 -1.2 -6.0 Sensor histidine kinase compare
Pf6N2E2_4097 -1.1 -7.9 FIG00953365: hypothetical protein compare
Pf6N2E2_1043 -1.1 -2.6 Transcriptional regulator, IclR family compare
Pf6N2E2_2253 -1.1 -1.5 hypothetical protein compare
Pf6N2E2_5342 -1.1 -2.2 21 kDa hemolysin precursor compare
Pf6N2E2_5705 -1.1 -2.8 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_5014 -1.1 -0.5 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_5723 -1.1 -5.5 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_3077 -1.1 -2.8 FIG138056: a glutathione-dependent thiol reductase compare
Pf6N2E2_3248 -1.1 -1.6 Probable transmembrane protein compare
Pf6N2E2_289 -1.1 -7.3 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_5262 -1.1 -1.5 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf6N2E2_5173 -1.1 -3.5 Hypothetical protein YqcC (clustered with tRNA pseudouridine synthase C) compare
Pf6N2E2_3534 -1.1 -2.0 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_5496 -1.1 -2.5 FIG00953991: hypothetical protein compare
Pf6N2E2_3251 -1.1 -5.5 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_3666 -1.1 -0.7 InaA protein compare
Pf6N2E2_3617 -1.1 -4.4 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_5157 -1.1 -6.0 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3786 -1.0 -4.2 Twin-arginine translocation protein TatC compare
Pf6N2E2_2640 -1.0 -1.5 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_2181 -1.0 -2.5 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_2384 -1.0 -1.0 CmpX compare
Pf6N2E2_3039 -1.0 -5.2 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_3658 -1.0 -3.8 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_2010 -1.0 -1.3 hypothetical protein compare
Pf6N2E2_673 -1.0 -2.6 Probable permease of ABC transporter compare
Pf6N2E2_5894 -1.0 -5.2 Putative threonine efflux protein compare
Pf6N2E2_2013 -1.0 -1.7 hypothetical protein compare
Pf6N2E2_2188 -1.0 -2.6 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_3612 -1.0 -2.3 HflK protein compare
Pf6N2E2_2752 -1.0 -1.8 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_3659 -1.0 -2.5 Protein fixF compare
Pf6N2E2_5338 -1.0 -8.0 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_5665 -1.0 -4.1 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_4824 -1.0 -3.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_1293 -1.0 -2.3 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_863 -1.0 -4.5 Transcriptional regulator, IclR family compare
Pf6N2E2_2588 -1.0 -1.9 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_4360 -1.0 -6.6 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_2017 -1.0 -2.7 DNA-binding protein compare
Pf6N2E2_54 -1.0 -3.5 Transcriptional regulator, TetR family compare


Specific Phenotypes

For 21 genes in this experiment

For denitrifying Sodium pyruvate in Pseudomonas fluorescens FW300-N2E2

For denitrifying Sodium pyruvate across organisms