Experiment set16IT034 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Nitrate reduction, replicate C

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_64 -6.4 -4.4 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3253 -5.4 -3.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3842 -5.0 -4.9 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3782 -5.0 -4.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3751 -4.9 -11.4 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3839 -4.8 -4.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4826 -4.8 -8.0 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_71 -4.8 -6.5 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4564 -4.8 -10.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4596 -4.7 -7.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_63 -4.7 -6.0 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4597 -4.6 -7.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4825 -4.6 -8.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3752 -4.5 -20.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3610 -4.4 -4.3 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_5177 -4.4 -10.9 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3932 -4.1 -5.2 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_66 -4.0 -10.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3841 -3.9 -3.8 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_2218 -3.6 -2.5 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_5239 -3.6 -15.1 Putative sulfate permease conserved
Pf6N2E2_4047 -3.6 -4.9 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4048 -3.6 -8.6 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3252 -3.6 -8.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5258 -3.5 -9.3 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_77 -3.4 -4.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_5223 -3.4 -6.8 Molybdopterin biosynthesis protein MoeB compare
Pf6N2E2_3630 -3.4 -6.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2323 -3.3 -3.8 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_1294 -3.3 -3.3 Carbon starvation protein A compare
Pf6N2E2_5242 -3.2 -2.2 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_3783 -3.2 -5.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_5337 -3.1 -16.6 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_3264 -3.1 -6.6 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_5338 -3.1 -22.0 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_2217 -3.1 -3.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_1656 -3.0 -2.0 hypothetical protein compare
Pf6N2E2_4473 -3.0 -10.2 HlyD family secretion protein compare
Pf6N2E2_5175 -2.9 -4.0 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3786 -2.9 -7.7 Twin-arginine translocation protein TatC compare
Pf6N2E2_3170 -2.8 -7.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_4351 -2.8 -12.5 Predicted signal transduction protein compare
Pf6N2E2_4472 -2.8 -15.8 ABC-type multidrug transport system, permease component compare
Pf6N2E2_5339 -2.8 -14.1 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_4471 -2.7 -10.7 ABC-type multidrug transport system, permease component compare
Pf6N2E2_5666 -2.7 -10.2 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_3074 -2.6 -1.5 FIG00960973: hypothetical protein compare
Pf6N2E2_2574 -2.6 -1.7 Flagellar synthesis regulator FleN compare
Pf6N2E2_2822 -2.5 -7.9 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_1296 -2.5 -6.2 DNA-binding response regulator, LuxR family compare
Pf6N2E2_3940 -2.5 -10.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4638 -2.4 -1.7 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2074 -2.4 -2.1 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_2465 -2.4 -5.7 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5024 -2.4 -5.6 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) compare
Pf6N2E2_728 -2.3 -4.1 Nitrate/nitrite transporter compare
Pf6N2E2_1293 -2.3 -2.0 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_5176 -2.3 -4.6 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3645 -2.2 -9.2 Type I secretion outer membrane protein, TolC precursor compare
Pf6N2E2_3763 -2.2 -1.5 hypothetical protein compare
Pf6N2E2_5257 -2.2 -8.6 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_2073 -2.2 -6.0 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4797 -2.2 -1.5 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_292 -2.2 -8.3 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Pf6N2E2_3282 -2.1 -2.1 FIG005080: Possible exported protein compare
Pf6N2E2_5023 -2.1 -7.2 Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) compare
Pf6N2E2_5299 -2.1 -8.0 Benzoate transport protein compare
Pf6N2E2_2389 -2.1 -8.7 Phosphoenolpyruvate synthase (EC 2.7.9.2) compare
Pf6N2E2_4372 -2.1 -4.3 FIG00460773: hypothetical protein compare
Pf6N2E2_302 -2.1 -4.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_477 -2.0 -6.4 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf6N2E2_5309 -2.0 -5.2 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_725 -2.0 -5.8 Nitrate/nitrite response regulator protein compare
Pf6N2E2_5728 -1.9 -4.4 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_3521 -1.9 -9.4 Sensor histidine kinase/response regulator compare
Pf6N2E2_4414 -1.9 -1.3 FIG00953808: hypothetical protein compare
Pf6N2E2_5646 -1.9 -1.7 PROBABLE MEMBRANE PROTEIN compare
Pf6N2E2_2390 -1.9 -2.1 FIG00959101: hypothetical protein compare
Pf6N2E2_2277 -1.8 -2.4 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_1083 -1.8 -1.5 hypothetical protein compare
Pf6N2E2_5843 -1.8 -2.4 hypothetical protein compare
Pf6N2E2_4590 -1.8 -3.9 Thiazole biosynthesis protein ThiG compare
Pf6N2E2_4984 -1.8 -2.6 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_730 -1.8 -8.7 Respiratory nitrate reductase beta chain (EC 1.7.99.4) compare
Pf6N2E2_4454 -1.8 -5.5 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_3255 -1.7 -3.8 YrbA protein compare
Pf6N2E2_3346 -1.7 -4.8 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_4818 -1.7 -5.7 Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) compare
Pf6N2E2_729 -1.7 -10.7 Respiratory nitrate reductase alpha chain (EC 1.7.99.4) conserved
Pf6N2E2_3251 -1.7 -8.7 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_1295 -1.6 -3.4 Sensor histidine kinase compare
Pf6N2E2_5394 -1.6 -3.8 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_405 -1.6 -2.0 hypothetical protein compare
Pf6N2E2_4803 -1.6 -1.1 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_4049 -1.6 -8.0 Glycine cleavage system transcriptional activator compare
Pf6N2E2_3248 -1.5 -1.7 Probable transmembrane protein compare
Pf6N2E2_2318 -1.5 -11.0 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_5080 -1.5 -6.9 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family compare
Pf6N2E2_546 -1.5 -1.7 FIG00966904: hypothetical protein compare
Pf6N2E2_1606 -1.5 -3.6 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_731 -1.5 -4.6 Respiratory nitrate reductase delta chain (EC 1.7.99.4) compare
Pf6N2E2_1445 -1.5 -2.2 Glutathione S-transferase compare
Pf6N2E2_3487 -1.5 -6.9 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_2013 -1.4 -2.1 hypothetical protein compare
Pf6N2E2_5308 -1.4 -9.1 Transcriptional regulator, AraC family compare
Pf6N2E2_1412 -1.4 -2.6 hypothetical protein compare
Pf6N2E2_732 -1.4 -4.9 Respiratory nitrate reductase gamma chain (EC 1.7.99.4) compare
Pf6N2E2_3257 -1.4 -1.9 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_5553 -1.4 -6.3 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_1249 -1.4 -2.7 Transcriptional regulator, AraC family compare
Pf6N2E2_4640 -1.4 -1.5 hypothetical protein compare
Pf6N2E2_5894 -1.4 -6.1 Putative threonine efflux protein compare
Pf6N2E2_2487 -1.4 -1.0 FIG00956090: hypothetical protein compare
Pf6N2E2_4187 -1.3 -6.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2320 -1.3 -5.4 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_5640 -1.3 -2.1 FIG00955597: hypothetical protein compare
Pf6N2E2_4817 -1.3 -9.8 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
Pf6N2E2_5316 -1.3 -1.7 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_6047 -1.3 -1.5 hypothetical protein compare
Pf6N2E2_204 -1.3 -2.0 hypothetical protein compare
Pf6N2E2_289 -1.3 -8.6 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_5593 -1.3 -2.8 Leucyl-tRNA synthetase compare
Pf6N2E2_2010 -1.3 -1.4 hypothetical protein compare
Pf6N2E2_4367 -1.3 -2.7 hypothetical protein compare
Pf6N2E2_718 -1.3 -2.1 Pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5) compare
Pf6N2E2_5157 -1.2 -6.4 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5295 -1.2 -4.4 Serine hydroxymethyltransferase (EC 2.1.2.1) compare
Pf6N2E2_1735 -1.2 -1.8 PhnB protein compare
Pf6N2E2_2506 -1.2 -7.1 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_3060 -1.2 -2.0 Outer membrane protein H precursor compare
Pf6N2E2_4813 -1.2 -9.1 Probable two-component sensor, near polyamine transporter compare
Pf6N2E2_3785 -1.2 -3.2 Twin-arginine translocation protein TatB compare
Pf6N2E2_3807 -1.2 -3.3 Histidine utilization repressor compare
Pf6N2E2_2681 -1.2 -1.1 3-phosphoglycerate kinase compare
Pf6N2E2_1673 -1.2 -1.5 Transcriptional regulator, TetR family compare
Pf6N2E2_4273 -1.2 -5.1 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_938 -1.2 -5.0 hypothetical protein compare
Pf6N2E2_451 -1.2 -2.2 transcriptional regulator MvaT, P16 subunit, putative compare
Pf6N2E2_5665 -1.2 -5.5 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_2071 -1.1 -2.3 hypothetical protein compare
Pf6N2E2_5647 -1.1 -3.9 Transcriptional regulator, TetR family compare
Pf6N2E2_1821 -1.1 -1.6 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_163 -1.1 -3.1 Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1) compare
Pf6N2E2_1932 -1.1 -2.1 Transcriptional regulator, IclR family compare
Pf6N2E2_5746 -1.1 -1.6 Cobalamin synthase compare
Pf6N2E2_813 -1.1 -1.5 Response regulator compare
Pf6N2E2_1009 -1.1 -2.1 Inositol transport system permease protein compare
Pf6N2E2_5014 -1.1 -0.5 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_5679 -1.1 -3.6 hypothetical protein compare
Pf6N2E2_3938 -1.1 -7.7 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3192 -1.1 -2.1 tRNA:Cm32/Um32 methyltransferase compare
Pf6N2E2_4987 -1.1 -1.3 MaoC-like domain protein compare
Pf6N2E2_5111 -1.1 -1.9 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_2068 -1.1 -3.3 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_6057 -1.0 -3.0 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_1605 -1.0 -3.8 Carboxynorspermidine dehydrogenase, putative (EC 1.1.1.-) compare
Pf6N2E2_3533 -1.0 -1.3 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_3340 -1.0 -6.8 Fructose repressor FruR, LacI family compare
Pf6N2E2_3661 -1.0 -2.0 hypothetical protein compare
Pf6N2E2_2569 -1.0 -5.8 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf6N2E2_1490 -1.0 -1.9 hypothetical protein compare
Pf6N2E2_2340 -1.0 -1.8 Transcriptional regulator, GntR family compare
Pf6N2E2_3373 -1.0 -2.8 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_2402 -1.0 -1.3 hypothetical protein compare
Pf6N2E2_5298 -1.0 -4.2 Sarcosine oxidase beta subunit (EC 1.5.3.1) compare
Pf6N2E2_1718 -1.0 -0.9 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_2510 -1.0 -1.6 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_2752 -1.0 -1.9 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_673 -1.0 -2.3 Probable permease of ABC transporter compare
Pf6N2E2_4579 -1.0 -0.9 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_5328 -1.0 -2.6 FIG00958649: hypothetical protein compare
Pf6N2E2_6130 -1.0 -2.6 5S RNA compare
Pf6N2E2_2507 -1.0 -4.0 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_2286 -1.0 -0.9 FIG00953287: hypothetical protein compare
Pf6N2E2_2513 -1.0 -1.4 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_3534 -1.0 -1.7 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_4205 -1.0 -2.3 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_5156 -1.0 -0.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5899 -1.0 -4.0 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_2384 -1.0 -0.9 CmpX compare
Pf6N2E2_5849 -1.0 -6.7 large component of pyruvate transporter (actP-like) (from data) compare
Pf6N2E2_5884 -1.0 -5.5 Sensor histidine kinase compare
Pf6N2E2_2568 -1.0 -4.3 Flagellar motor rotation protein MotA compare
Pf6N2E2_3151 -1.0 -3.6 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_291 -1.0 -3.6 ATP-dependent Clp protease adaptor protein ClpS compare
Pf6N2E2_1652 -1.0 -1.5 Transcriptional regulator, TetR family compare
Pf6N2E2_3260 -1.0 -2.3 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_5520 -1.0 -3.7 Sensory box histidine kinase compare
Pf6N2E2_699 -0.9 -3.8 Heme d1 biosynthesis protein NirG compare
Pf6N2E2_3033 -0.9 -1.7 hypothetical protein compare
Pf6N2E2_895 -0.9 -2.7 Transcriptional regulator, HxlR family compare
Pf6N2E2_1072 -0.9 -3.6 LmbE-like protein compare
Pf6N2E2_4415 -0.9 -1.7 Putative FMN hydrolase (EC 3.1.3.-); 5-Amino-6-(5'-phosphoribitylamino)uracil phosphatase compare
Pf6N2E2_4298 -0.9 -1.9 Uncharacterized protein ImpB compare
Pf6N2E2_1705 -0.9 -1.7 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_613 -0.9 -1.1 lipoprotein, putative compare
Pf6N2E2_4159 -0.9 -4.4 Cytochrome c4 compare
Pf6N2E2_3312 -0.9 -3.3 Dipeptide transport system permease protein DppC (TC 3.A.1.5.2) compare
Pf6N2E2_3933 -0.9 -4.9 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_5780 -0.9 -4.5 Periplasmic protease compare


Specific Phenotypes

For 13 genes in this experiment

For denitrifying Sodium pyruvate in Pseudomonas fluorescens FW300-N2E2

For denitrifying Sodium pyruvate across organisms