Experiment set16IT032 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Nitrate reduction in presence of wild-type Pseudomonas N1-B4; replicate A

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_5394 -6.8 -4.7 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_64 -6.5 -4.4 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4825 -6.0 -4.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3630 -5.9 -4.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3782 -5.8 -4.0 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3839 -5.7 -3.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_736 -5.7 -3.9 hypothetical protein compare
Pf6N2E2_4826 -5.6 -6.6 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3253 -5.4 -3.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4564 -5.4 -7.4 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4473 -5.3 -11.2 HlyD family secretion protein compare
Pf6N2E2_1294 -5.2 -3.5 Carbon starvation protein A compare
Pf6N2E2_3842 -5.2 -5.0 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_2323 -5.0 -3.4 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_5239 -5.0 -12.5 Putative sulfate permease conserved
Pf6N2E2_4472 -5.0 -16.5 ABC-type multidrug transport system, permease component compare
Pf6N2E2_5177 -4.9 -9.9 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_63 -4.8 -5.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3751 -4.8 -13.4 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3645 -4.7 -12.4 Type I secretion outer membrane protein, TolC precursor compare
Pf6N2E2_477 -4.7 -7.0 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf6N2E2_4596 -4.7 -9.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3932 -4.7 -6.6 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_5309 -4.6 -7.3 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_3610 -4.6 -4.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3783 -4.6 -5.5 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3252 -4.6 -8.3 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_729 -4.6 -14.3 Respiratory nitrate reductase alpha chain (EC 1.7.99.4) conserved
Pf6N2E2_71 -4.5 -6.1 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3752 -4.5 -20.9 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4597 -4.4 -8.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_66 -4.4 -9.3 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3300 -4.2 -2.9 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_77 -4.1 -4.0 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_718 -4.1 -5.4 Pyridoxamine 5'-phosphate oxidase (EC 1.4.3.5) compare
Pf6N2E2_5223 -4.0 -7.1 Molybdopterin biosynthesis protein MoeB compare
Pf6N2E2_735 -3.9 -14.5 Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) conserved
Pf6N2E2_4048 -3.9 -7.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3841 -3.9 -3.8 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4351 -3.8 -14.3 Predicted signal transduction protein compare
Pf6N2E2_730 -3.8 -9.5 Respiratory nitrate reductase beta chain (EC 1.7.99.4) compare
Pf6N2E2_4047 -3.8 -5.2 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3487 -3.7 -10.1 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_732 -3.7 -7.4 Respiratory nitrate reductase gamma chain (EC 1.7.99.4) compare
Pf6N2E2_711 -3.7 -8.5 Nitric oxide reductase activation protein NorD conserved
Pf6N2E2_5258 -3.6 -9.5 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_725 -3.6 -6.3 Nitrate/nitrite response regulator protein compare
Pf6N2E2_5392 -3.5 -3.4 Molybdenum cofactor biosynthesis protein MoaC compare
Pf6N2E2_4921 -3.5 -4.8 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) compare
Pf6N2E2_721 -3.5 -9.0 FIG139552: Putative protease compare
Pf6N2E2_731 -3.5 -5.3 Respiratory nitrate reductase delta chain (EC 1.7.99.4) compare
Pf6N2E2_3346 -3.5 -7.6 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_4797 -3.4 -2.2 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_4471 -3.3 -8.3 ABC-type multidrug transport system, permease component compare
Pf6N2E2_726 -3.3 -4.5 Nitrate/nitrite sensor protein (EC 2.7.3.-) compare
Pf6N2E2_1412 -3.3 -3.8 hypothetical protein compare
Pf6N2E2_706 -3.2 -6.9 Nitric oxide reductase activation protein NorQ compare
Pf6N2E2_5242 -3.2 -2.2 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_1296 -3.2 -7.0 DNA-binding response regulator, LuxR family compare
Pf6N2E2_2218 -3.2 -3.7 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_737 -3.1 -2.1 Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) compare
Pf6N2E2_2217 -3.1 -3.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_2073 -3.1 -6.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4372 -3.1 -3.6 FIG00460773: hypothetical protein compare
Pf6N2E2_5308 -3.0 -13.4 Transcriptional regulator, AraC family compare
Pf6N2E2_722 -3.0 -7.8 FIG139928: Putative protease compare
Pf6N2E2_5176 -2.9 -3.4 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_2389 -2.9 -9.8 Phosphoenolpyruvate synthase (EC 2.7.9.2) compare
Pf6N2E2_5175 -2.9 -4.7 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3264 -2.8 -4.1 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_2507 -2.8 -7.1 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_2181 -2.8 -4.6 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_432 -2.8 -7.1 Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1) compare
Pf6N2E2_2465 -2.8 -5.8 Cys regulon transcriptional activator CysB compare
Pf6N2E2_4049 -2.7 -12.0 Glycine cleavage system transcriptional activator compare
Pf6N2E2_5666 -2.7 -11.5 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_1293 -2.6 -1.9 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_3074 -2.6 -1.4 FIG00960973: hypothetical protein compare
Pf6N2E2_4638 -2.5 -1.7 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_4813 -2.5 -13.7 Probable two-component sensor, near polyamine transporter compare
Pf6N2E2_5841 -2.5 -1.2 GlcG protein compare
Pf6N2E2_3255 -2.4 -4.5 YrbA protein compare
Pf6N2E2_431 -2.4 -5.8 Molybdenum transport system permease protein ModB (TC 3.A.1.8.1) compare
Pf6N2E2_3170 -2.4 -5.6 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5299 -2.4 -9.3 Benzoate transport protein compare
Pf6N2E2_3940 -2.3 -9.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5080 -2.3 -9.5 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family compare
Pf6N2E2_1886 -2.3 -3.0 hypothetical protein compare
Pf6N2E2_733 -2.2 -4.2 Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8) compare
Pf6N2E2_3248 -2.2 -2.1 Probable transmembrane protein compare
Pf6N2E2_5553 -2.2 -5.8 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_5728 -2.2 -3.4 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_1411 -2.2 -7.6 Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) compare
Pf6N2E2_760 -2.2 -11.8 Na+/H+ antiporter NhaB compare
Pf6N2E2_723 -2.2 -4.8 FIG138517: Putative lipid carrier protein compare
Pf6N2E2_4612 -2.2 -3.3 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_709 -2.1 -7.9 Nitric-oxide reductase subunit C (EC 1.7.99.7) compare
Pf6N2E2_2424 -2.1 -2.4 Molybdopterin-guanine dinucleotide biosynthesis protein MobA compare
Pf6N2E2_728 -2.1 -2.3 Nitrate/nitrite transporter compare
Pf6N2E2_5520 -2.0 -6.1 Sensory box histidine kinase compare
Pf6N2E2_3984 -2.0 -11.6 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_3807 -2.0 -5.9 Histidine utilization repressor compare
Pf6N2E2_5328 -2.0 -5.9 FIG00958649: hypothetical protein compare
Pf6N2E2_289 -2.0 -9.6 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_4414 -2.0 -1.3 FIG00953808: hypothetical protein compare
Pf6N2E2_2277 -2.0 -2.6 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5257 -1.9 -7.3 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_3282 -1.9 -1.8 FIG005080: Possible exported protein compare
Pf6N2E2_4187 -1.9 -8.2 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_292 -1.9 -7.7 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Pf6N2E2_3132 -1.9 -3.7 FIG00954548: hypothetical protein compare
Pf6N2E2_2074 -1.8 -1.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4273 -1.8 -6.8 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_2824 -1.8 -9.4 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_2447 -1.8 -5.5 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_3763 -1.8 -1.7 hypothetical protein compare
Pf6N2E2_1673 -1.8 -2.4 Transcriptional regulator, TetR family compare
Pf6N2E2_5295 -1.8 -3.7 Serine hydroxymethyltransferase (EC 2.1.2.1) compare
Pf6N2E2_710 -1.8 -8.3 Nitric-oxide reductase subunit B (EC 1.7.99.7) conserved
Pf6N2E2_3847 -1.8 -2.6 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_1295 -1.7 -3.6 Sensor histidine kinase compare
Pf6N2E2_3658 -1.7 -4.9 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_4803 -1.7 -1.1 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_4817 -1.7 -11.9 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
Pf6N2E2_2390 -1.7 -2.6 FIG00959101: hypothetical protein compare
Pf6N2E2_2506 -1.6 -8.8 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_2758 -1.6 -11.4 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_2510 -1.6 -1.5 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_717 -1.6 -6.9 Functional role page for Anaerobic nitric oxide reductase transcription regulator NorR compare
Pf6N2E2_3661 -1.6 -2.5 hypothetical protein compare
Pf6N2E2_1885 -1.6 -3.2 Transcriptional regulator, AraC family compare
Pf6N2E2_2574 -1.6 -1.4 Flagellar synthesis regulator FleN compare
Pf6N2E2_2681 -1.5 -1.0 3-phosphoglycerate kinase compare
Pf6N2E2_2180 -1.5 -3.4 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_3251 -1.5 -7.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_5884 -1.5 -7.7 Sensor histidine kinase compare
Pf6N2E2_2422 -1.5 -7.1 Molybdopterin biosynthesis protein MoeA compare
Pf6N2E2_3326 -1.5 -2.1 hypothetical protein compare
Pf6N2E2_2186 -1.5 -4.9 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_2340 -1.5 -2.8 Transcriptional regulator, GntR family compare
Pf6N2E2_3340 -1.5 -8.8 Fructose repressor FruR, LacI family compare
Pf6N2E2_4818 -1.5 -5.6 Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) compare
Pf6N2E2_712 -1.4 -2.5 hypothetical protein compare
Pf6N2E2_5252 -1.4 -2.0 FIG00956396: hypothetical protein compare
Pf6N2E2_863 -1.4 -6.2 Transcriptional regulator, IclR family compare
Pf6N2E2_5471 -1.4 -5.9 Transcriptional activator MetR compare
Pf6N2E2_4918 -1.3 -2.2 Ribonucleotide reductase transcriptional regulator NrdR compare
Pf6N2E2_5291 -1.3 -9.4 Fumarylacetoacetase (EC 3.7.1.2) compare
Pf6N2E2_5111 -1.3 -1.6 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_2508 -1.3 -3.5 hypothetical protein compare
Pf6N2E2_3039 -1.3 -6.0 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_5679 -1.3 -4.0 hypothetical protein compare
Pf6N2E2_2509 -1.3 -1.7 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_4743 -1.3 -1.5 hypothetical protein compare
Pf6N2E2_727 -1.3 -3.8 Nitrate/nitrite transporter compare
Pf6N2E2_2825 -1.3 -4.2 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_2865 -1.3 -8.7 Gluconate utilization system Gnt-I transcriptional repressor compare
Pf6N2E2_1089 -1.3 -2.8 Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) / Delta 1-pyrroline-2-carboxylate reductase (EC 1.5.1.1) compare
Pf6N2E2_2572 -1.2 -3.0 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_4097 -1.2 -9.0 FIG00953365: hypothetical protein compare
Pf6N2E2_338 -1.2 -1.4 Transcriptional regulator, AraC family compare
Pf6N2E2_2371 -1.2 -1.9 Type III secretion outermembrane contact sensing protein (YopN,Yop4b,LcrE) compare
Pf6N2E2_3933 -1.2 -6.4 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_2059 -1.2 -1.8 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_4454 -1.2 -4.6 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_3655 -1.2 -9.7 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_74 -1.2 -1.7 DedD protein compare
Pf6N2E2_5571 -1.2 -1.5 hypothetical protein compare
Pf6N2E2_2752 -1.2 -1.4 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_2253 -1.2 -1.7 hypothetical protein compare
Pf6N2E2_291 -1.2 -3.3 ATP-dependent Clp protease adaptor protein ClpS compare
Pf6N2E2_2822 -1.2 -4.0 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_5647 -1.2 -4.2 Transcriptional regulator, TetR family compare
Pf6N2E2_302 -1.2 -3.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2201 -1.2 -2.5 Transmembrane regulator protein PrtR compare
Pf6N2E2_3521 -1.2 -6.7 Sensor histidine kinase/response regulator compare
Pf6N2E2_5740 -1.2 -2.3 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf6N2E2_2674 -1.2 -0.9 FIG00953856: hypothetical protein compare
Pf6N2E2_5014 -1.2 -0.5 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3328 -1.1 -1.9 transcriptional regulator compare
Pf6N2E2_50 -1.1 -5.5 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_1037 -1.1 -2.2 hypothetical protein compare
Pf6N2E2_2402 -1.1 -1.4 hypothetical protein compare
Pf6N2E2_2564 -1.1 -3.7 Positive regulator of CheA protein activity (CheW) compare
Pf6N2E2_3659 -1.1 -2.6 Protein fixF compare
Pf6N2E2_5298 -1.1 -4.8 Sarcosine oxidase beta subunit (EC 1.5.3.1) compare
Pf6N2E2_5936 -1.1 -1.5 Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) compare
Pf6N2E2_156 -1.1 -1.7 Carbon storage regulator compare
Pf6N2E2_4579 -1.1 -1.0 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_5665 -1.1 -4.4 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_2189 -1.1 -3.0 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_510 -1.1 -5.7 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf6N2E2_4059 -1.1 -1.1 DNA-binding protein HU-alpha compare
Pf6N2E2_945 -1.1 -1.5 Transcriptional regulator, TetR family compare
Pf6N2E2_2292 -1.1 -2.8 Universal stress protein family COG0589 compare
Pf6N2E2_4607 -1.0 -2.2 Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR compare
Pf6N2E2_4476 -1.0 -3.8 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_2823 -1.0 -3.4 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_4360 -1.0 -6.9 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_4415 -1.0 -2.0 Putative FMN hydrolase (EC 3.1.3.-); 5-Amino-6-(5'-phosphoribitylamino)uracil phosphatase compare


Specific Phenotypes

For 24 genes in this experiment

For denitrifying Sodium pyruvate in Pseudomonas fluorescens FW300-N2E2

For denitrifying Sodium pyruvate across organisms