Experiment set15S714 for Methanococcus maripaludis S2

Compare to:

H2 50 mM hypophosphite

200 most important genes:

  gene name fitness t score description  
MMP_RS01545 -4.2 -1.5 CBS domain-containing protein compare
MMP_RS00735 -4.2 -2.7 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS05930 -2.7 -1.9 3-isopropylmalate dehydratase large subunit compare
MMP_RS01365 -2.3 -2.6 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS00315 -2.2 -5.4 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS07700 -2.1 -8.3 DUF1188 domain-containing protein compare
MMP_RS01720 -2.1 -2.3 replication factor C large subunit compare
MMP_RS05920 -2.0 -0.7 50S ribosomal protein L37e compare
MMP_RS06710 -1.9 -4.0 selenium-binding protein compare
MMP_RS00310 -1.9 -8.3 CBS domain-containing protein compare
MMP_RS00730 -1.9 -3.7 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS00455 -1.9 -8.6 orotate phosphoribosyltransferase-like protein compare
MMP_RS00515 -1.8 -0.9 DUF655 domain-containing protein compare
MMP_RS00150 -1.8 -6.9 AAA family ATPase compare
MMP_RS00720 -1.8 -5.7 metal-dependent hydrolase compare
MMP_RS07695 -1.8 -5.6 DUF3236 domain-containing protein compare
MMP_RS02280 -1.7 -0.9 DUF211 domain-containing protein compare
MMP_RS08435 -1.7 -2.0 Era-like GTP-binding protein compare
MMP_RS03550 -1.7 -1.6 DUF2124 domain-containing protein compare
MMP_RS07380 -1.6 -1.6 transcription elongation factor Spt5 compare
MMP_RS06275 -1.6 -5.8 ATP-dependent DNA helicase compare
MMP_RS07365 -1.6 -7.4 2-phosphoglycerate kinase compare
MMP_RS04955 -1.6 -3.4 DNA topoisomerase I compare
MMP_RS06980 -1.6 -4.6 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS03640 -1.6 -1.9 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01500 -1.6 -1.8 CBS domain-containing protein compare
MMP_RS00625 -1.6 -4.9 hypothetical protein compare
MMP_RS07425 -1.5 -3.2 GTP-binding protein compare
MMP_RS00725 -1.5 -4.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS00945 -1.5 -1.3 PadR family transcriptional regulator compare
MMP_RS07880 -1.5 -7.0 AAA family ATPase compare
MMP_RS06110 -1.5 -2.0 ATP-dependent protease LonB compare
MMP_RS02875 -1.5 -4.9 chorismate pyruvate-lyase family protein compare
MMP_RS06885 -1.4 -1.8 50S ribosome-binding GTPase compare
MMP_RS03205 -1.4 -0.8 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS06920 -1.4 -6.5 AAA family ATPase compare
MMP_RS07605 -1.4 -3.1 diadenylate cyclase compare
MMP_RS06770 -1.4 -6.0 DHH family phosphoesterase compare
MMP_RS07130 -1.4 -6.6 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS00675 -1.4 -0.9 nitroreductase family protein compare
MMP_RS02340 -1.4 -2.1 DNA-directed RNA polymerase subunit E'' compare
MMP_RS05525 -1.4 -3.5 calcium/sodium antiporter compare
MMP_RS05535 -1.3 -4.0 hypothetical protein compare
MMP_RS00850 -1.3 -4.3 TIGR01177 family methyltransferase compare
MMP_RS08460 -1.3 -1.8 proteasome-activating nucleotidase compare
MMP_RS01610 -1.3 -1.9 hypothetical protein compare
MMP_RS09055 -1.3 -0.9 CAP domain-containing protein compare
MMP_RS04485 -1.3 -6.2 putative beta-lysine N-acetyltransferase compare
MMP_RS02165 -1.2 -4.3 tRNA-dihydrouridine synthase compare
MMP_RS08615 -1.2 -1.6 flagellar protein G compare
MMP_RS08785 -1.2 -0.9 RNA-protein complex protein Nop10 compare
MMP_RS07555 -1.2 -0.6 monovalent cation/H+ antiporter subunit E compare
MMP_RS01180 -1.2 -1.5 XTP/dITP diphosphatase compare
MMP_RS05550 -1.2 -0.6 cation:proton antiporter compare
MMP_RS06290 -1.2 -2.5 DNA repair and recombination protein RadA compare
MMP_RS03215 -1.2 -6.6 MBL fold metallo-hydrolase compare
MMP_RS01895 -1.2 -6.2 flippase compare
MMP_RS06585 -1.2 -1.2 DMT family protein compare
MMP_RS07120 -1.2 -4.8 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS07685 -1.2 -5.0 TIGR01212 family radical SAM protein compare
MMP_RS00750 -1.2 -1.6 fumarate hydratase compare
MMP_RS06500 -1.2 -5.4 ATP-binding protein compare
MMP_RS01880 -1.2 -2.2 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS08370 -1.2 -0.6 cation:proton antiporter subunit C compare
MMP_RS00535 -1.1 -2.6 TIGR00375 family protein compare
MMP_RS06725 -1.1 -4.0 hypothetical protein compare
MMP_RS01380 -1.1 -2.6 PHP domain-containing protein compare
MMP_RS05365 -1.1 -1.5 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS06200 -1.1 -6.1 M24 family metallopeptidase compare
MMP_RS07135 -1.1 -5.4 coenzyme F420 hydrogenase subunit beta compare
MMP_RS05765 -1.1 -3.5 M42 family metallopeptidase compare
MMP_RS01935 -1.1 -4.6 DUF58 domain-containing protein compare
MMP_RS06495 -1.1 -2.6 YkgJ family cysteine cluster protein compare
MMP_RS00695 -1.0 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06915 -1.0 -2.5 metallophosphoesterase compare
MMP_RS01385 -1.0 -0.5 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS07750 -1.0 -2.7 DUF357 domain-containing protein compare
MMP_RS06015 -1.0 -3.2 flavodoxin family protein compare
MMP_RS00685 -1.0 -2.0 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07525 -1.0 -4.0 4Fe-4S binding protein compare
MMP_RS01335 -1.0 -1.7 prefoldin subunit beta compare
MMP_RS06865 -1.0 -1.7 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS04850 -1.0 -6.1 UPF0254 family protein compare
MMP_RS03035 -1.0 -1.7 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS02830 -0.9 -4.6 DUF432 domain-containing protein compare
MMP_RS01950 -0.9 -5.1 hypothetical protein compare
MMP_RS06020 -0.9 -1.8 archaeoflavoprotein AfpA compare
MMP_RS08340 -0.9 -2.0 4Fe-4S binding protein compare
MMP_RS08350 -0.9 -0.6 hypothetical protein compare
MMP_RS01175 -0.9 -2.9 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS02355 -0.9 -1.4 30S ribosomal protein S27ae compare
MMP_RS08355 -0.9 -3.4 Na(+)/H(+) antiporter subunit B compare
MMP_RS07115 -0.9 -4.4 MBL fold metallo-hydrolase compare
MMP_RS00620 -0.9 -3.3 4Fe-4S binding protein compare
MMP_RS01970 -0.9 -3.1 TIGR04279 domain-containing protein compare
MMP_RS01975 -0.9 -4.8 hypothetical protein compare
MMP_RS05285 -0.9 -4.0 MMPL family transporter compare
MMP_RS06840 -0.8 -0.6 DNA-directed RNA polymerase subunit N compare
MMP_RS00810 -0.8 -2.6 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS08940 -0.8 -0.8 MetS family NSS transporter small subunit compare
MMP_RS01195 -0.8 -0.8 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01945 -0.8 -3.1 DUF4350 domain-containing protein compare
MMP_RS04480 -0.8 -6.0 lysine 2 3-aminomutase compare
MMP_RS08690 -0.8 -2.9 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS06395 -0.8 -1.5 ThiF family adenylyltransferase compare
MMP_RS04585 -0.8 -3.5 AIR synthase related protein compare
MMP_RS03895 -0.8 -1.2 hypothetical protein compare
MMP_RS00320 -0.8 -1.0 class I SAM-dependent methyltransferase compare
MMP_RS00895 -0.8 -1.9 hypothetical protein compare
MMP_RS01445 -0.8 -2.1 hypothetical protein compare
MMP_RS00060 -0.8 -0.7 3-dehydroquinate synthase II compare
MMP_RS04015 -0.8 -1.4 hypothetical protein compare
MMP_RS02495 -0.8 -1.4 hypothetical protein compare
MMP_RS00110 -0.7 -1.4 hypothetical protein compare
MMP_RS08365 -0.7 -2.0 energy conserving hydrogenase EhbF compare
MMP_RS01475 -0.7 -3.4 phosphosulfolactate synthase compare
MMP_RS01780 -0.7 -3.0 TrmJ/YjtD family RNA methyltransferase compare
MMP_RS00900 -0.7 -1.0 50S ribosomal protein L39e compare
MMP_RS08225 -0.7 -2.4 RimK family alpha-L-glutamate ligase compare
MMP_RS07860 -0.7 -0.4 hypothetical protein compare
MMP_RS01885 -0.7 -1.0 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01980 -0.7 -4.4 trimeric intracellular cation channel family protein compare
MMP_RS06225 -0.7 -3.5 DNA double-strand break repair nuclease NurA compare
MMP_RS07970 -0.7 -1.6 hypothetical protein compare
MMP_RS00325 -0.7 -1.0 RNA-binding protein compare
MMP_RS06925 -0.7 -1.1 ribonuclease VapC4 compare
MMP_RS02175 -0.7 -0.4 DUF1611 domain-containing protein compare
MMP_RS08290 -0.7 -2.6 DNA-binding protein Alba compare
MMP_RS05875 -0.7 -2.1 hydroxyethylthiazole kinase compare
MMP_RS08790 -0.7 -0.8 translation initiation factor IF-2 subunit alpha compare
MMP_RS02825 -0.7 -3.5 mechanosensitive ion channel family protein compare
MMP_RS05290 -0.6 -3.0 TetR/AcrR family transcriptional regulator compare
MMP_RS01470 -0.6 -1.5 ATP-binding cassette domain-containing protein compare
MMP_RS08915 -0.6 -1.9 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS02425 -0.6 -2.2 hypothetical protein compare
MMP_RS02045 -0.6 -0.8 tRNA-Met compare
MMP_RS03755 -0.6 -3.8 MarR family transcriptional regulator compare
MMP_RS05280 -0.6 -2.8 COG1361 S-layer family protein compare
MMP_RS01755 -0.6 -0.6 DUF2097 domain-containing protein compare
MMP_RS01790 -0.6 -3.7 restriction endonuclease compare
MMP_RS08280 -0.6 -0.9 proteasome assembly chaperone family protein compare
MMP_RS03420 -0.6 -1.3 acetolactate synthase small subunit compare
MMP_RS07725 -0.6 -1.4 4Fe-4S dicluster domain-containing protein compare
MMP_RS07125 -0.6 -1.9 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS02935 -0.6 -1.9 A24 family peptidase compare
MMP_RS00570 -0.6 -0.8 protein-L-isoaspartate O-methyltransferase compare
MMP_RS03220 -0.6 -1.1 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS05975 -0.6 -0.7 hypothetical protein compare
MMP_RS05430 -0.6 -2.9 TIGR00288 family NYN domain-containing protein compare
MMP_RS06935 -0.6 -1.7 protease complex subunit PrcB family protein compare
MMP_RS04050 -0.6 -1.3 hypothetical protein compare
MMP_RS07535 -0.6 -2.9 4Fe-4S binding protein compare
MMP_RS04670 -0.6 -2.6 selenouridine synthase SelU-like subunit compare
MMP_RS02190 -0.6 -1.4 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS00520 -0.6 -0.6 RNA polymerase Rpb4 family protein compare
MMP_RS01875 -0.5 -1.4 N-acetyltransferase compare
MMP_RS03740 -0.5 -1.5 indolepyruvate oxidoreductase subunit beta compare
MMP_RS00235 -0.5 -2.4 HDIG domain-containing protein conserved
MMP_RS05445 -0.5 -2.6 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS05665 -0.5 -1.6 phosphate ABC transporter permease subunit PstC compare
MMP_RS07650 -0.5 -2.8 TldD/PmbA family protein compare
MMP_RS02940 -0.5 -2.2 TatD family hydrolase compare
MMP_RS07720 -0.5 -3.0 4Fe-4S binding protein compare
MMP_RS05295 -0.5 -2.3 minichromosome maintenance protein MCM compare
MMP_RS04870 -0.5 -1.2 TIGR02253 family HAD-type hydrolase compare
MMP_RS03250 -0.5 -1.6 MJ1244 family protein compare
MMP_RS02085 -0.5 -2.7 inosine/xanthosine triphosphatase compare
MMP_RS05540 -0.5 -1.1 hypothetical protein compare
MMP_RS02805 -0.5 -0.5 HEPN domain-containing protein compare
MMP_RS01920 -0.5 -2.1 glycosyltransferase family 2 protein compare
MMP_RS02740 -0.5 -0.9 hypothetical protein compare
MMP_RS03080 -0.5 -1.3 universal stress protein compare
MMP_RS00335 -0.5 -0.9 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS06760 -0.5 -1.0 hypothetical protein compare
MMP_RS08705 -0.5 -2.1 sulfopyruvate decarboxylase subunit beta compare
MMP_RS05460 -0.5 -2.0 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS07960 -0.5 -1.7 sugar phosphate isomerase/epimerase compare
MMP_RS08645 -0.5 -1.8 UPF0179 family protein compare
MMP_RS03095 -0.5 -1.5 diphthine synthase compare
MMP_RS02770 -0.5 -1.9 hypothetical protein compare
MMP_RS02930 -0.5 -1.0 class I SAM-dependent methyltransferase compare
MMP_RS04290 -0.5 -2.3 4Fe-4S binding protein compare
MMP_RS02110 -0.5 -0.6 hypothetical protein compare
MMP_RS01840 -0.5 -1.9 TIGR00289 family protein compare
MMP_RS03485 -0.4 -1.2 TIGR00267 family protein compare
MMP_RS03130 -0.4 -2.3 hypothetical protein compare
MMP_RS07005 -0.4 -0.2 4Fe-4S binding protein compare
MMP_RS05095 -0.4 -1.9 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS02965 -0.4 -1.3 carboxymuconolactone decarboxylase family protein compare
MMP_RS02595 -0.4 -0.5 putative zinc-binding protein compare
MMP_RS00380 -0.4 -1.0 P-II family nitrogen regulator compare
MMP_RS05950 -0.4 -1.5 nickel-dependent hydrogenase large subunit compare
MMP_RS08930 -0.4 -0.7 hypothetical protein compare
MMP_RS02575 -0.4 -2.4 CAAX prenyl protease Rce1 compare
MMP_RS04410 -0.4 -1.2 hypothetical protein compare
MMP_RS05355 -0.4 -0.3 hypothetical protein compare
MMP_RS04995 -0.4 -2.3 hypothetical protein compare
MMP_RS06600 -0.4 -0.3 class III signal peptide-containing protein compare
MMP_RS06215 -0.4 -0.9 30S ribosomal protein S6e compare
MMP_RS00050 -0.4 -1.4 AarF/UbiB family protein compare


Specific Phenotypes

For 13 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis S2

For stress Sodium hypophosphite across organisms