Experiment set15S713 for Methanococcus maripaludis S2

Compare to:

H2 50 mM hypophosphite

200 most important genes:

  gene name fitness t score description  
MMP_RS02805 -3.7 -1.4 HEPN domain-containing protein compare
MMP_RS01365 -3.4 -3.3 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS01545 -3.2 -1.2 CBS domain-containing protein compare
MMP_RS00725 -2.8 -5.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS01500 -2.7 -1.7 CBS domain-containing protein compare
MMP_RS00315 -2.6 -4.4 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS00720 -2.5 -4.6 metal-dependent hydrolase compare
MMP_RS06500 -2.5 -4.7 ATP-binding protein compare
MMP_RS00395 -2.5 -1.6 MGMT family protein compare
MMP_RS08940 -2.4 -1.3 MetS family NSS transporter small subunit compare
MMP_RS00810 -2.3 -4.4 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS00325 -2.2 -1.6 RNA-binding protein compare
MMP_RS02875 -2.2 -4.5 chorismate pyruvate-lyase family protein compare
MMP_RS00455 -2.2 -6.2 orotate phosphoribosyltransferase-like protein compare
MMP_RS07845 -2.2 -1.8 LL-diaminopimelate aminotransferase compare
MMP_RS06760 -2.1 -2.9 hypothetical protein compare
MMP_RS06215 -2.1 -1.9 30S ribosomal protein S6e compare
MMP_RS06980 -2.1 -4.8 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS00310 -2.1 -7.4 CBS domain-containing protein compare
MMP_RS06395 -2.0 -2.4 ThiF family adenylyltransferase compare
MMP_RS06015 -2.0 -4.5 flavodoxin family protein compare
MMP_RS00320 -2.0 -1.4 class I SAM-dependent methyltransferase compare
MMP_RS06920 -2.0 -6.1 AAA family ATPase compare
MMP_RS07695 -1.9 -3.1 DUF3236 domain-containing protein compare
MMP_RS06275 -1.9 -4.7 ATP-dependent DNA helicase compare
MMP_RS00625 -1.9 -4.5 hypothetical protein compare
MMP_RS02340 -1.8 -1.2 DNA-directed RNA polymerase subunit E'' compare
MMP_RS07365 -1.8 -6.1 2-phosphoglycerate kinase compare
MMP_RS01085 -1.8 -1.7 hypothetical protein compare
MMP_RS07700 -1.8 -5.7 DUF1188 domain-containing protein compare
MMP_RS07120 -1.8 -6.5 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS07555 -1.8 -0.7 monovalent cation/H+ antiporter subunit E compare
MMP_RS06710 -1.7 -3.6 selenium-binding protein compare
MMP_RS00150 -1.7 -5.0 AAA family ATPase compare
MMP_RS04125 -1.7 -2.1 TetR/AcrR family transcriptional regulator compare
MMP_RS04485 -1.7 -6.3 putative beta-lysine N-acetyltransferase compare
MMP_RS06495 -1.7 -2.5 YkgJ family cysteine cluster protein compare
MMP_RS00335 -1.7 -3.7 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS09055 -1.7 -0.9 CAP domain-containing protein compare
MMP_RS05280 -1.7 -4.8 COG1361 S-layer family protein compare
MMP_RS03550 -1.7 -1.5 DUF2124 domain-containing protein compare
MMP_RS04850 -1.6 -6.8 UPF0254 family protein compare
MMP_RS01610 -1.6 -1.9 hypothetical protein compare
MMP_RS00730 -1.6 -2.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS07605 -1.6 -2.2 diadenylate cyclase compare
MMP_RS06915 -1.6 -3.5 metallophosphoesterase compare
MMP_RS07880 -1.6 -5.5 AAA family ATPase compare
MMP_RS05550 -1.6 -0.6 cation:proton antiporter compare
MMP_RS06770 -1.6 -4.0 DHH family phosphoesterase compare
MMP_RS03215 -1.6 -5.9 MBL fold metallo-hydrolase compare
MMP_RS01720 -1.6 -1.6 replication factor C large subunit compare
MMP_RS05430 -1.6 -4.3 TIGR00288 family NYN domain-containing protein compare
MMP_RS05765 -1.5 -3.0 M42 family metallopeptidase compare
MMP_RS08570 -1.5 -4.9 coenzyme F420-0:L-glutamate ligase compare
MMP_RS07685 -1.5 -4.8 TIGR01212 family radical SAM protein compare
MMP_RS07115 -1.5 -3.9 MBL fold metallo-hydrolase compare
MMP_RS08645 -1.4 -3.8 UPF0179 family protein compare
MMP_RS07135 -1.4 -4.8 coenzyme F420 hydrogenase subunit beta compare
MMP_RS02165 -1.4 -3.6 tRNA-dihydrouridine synthase compare
MMP_RS01895 -1.4 -4.2 flippase compare
MMP_RS05950 -1.3 -3.9 nickel-dependent hydrogenase large subunit compare
MMP_RS00735 -1.3 -1.7 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS08350 -1.3 -0.7 hypothetical protein compare
MMP_RS01975 -1.3 -5.3 hypothetical protein compare
MMP_RS06105 -1.3 -3.3 hydrogenase maturation peptidase HycI compare
MMP_RS06290 -1.3 -2.3 DNA repair and recombination protein RadA compare
MMP_RS02940 -1.2 -3.4 TatD family hydrolase compare
MMP_RS06120 -1.2 -0.8 UPF0147 family protein compare
MMP_RS06200 -1.2 -4.8 M24 family metallopeptidase compare
MMP_RS06900 -1.2 -1.4 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS07960 -1.2 -4.3 sugar phosphate isomerase/epimerase compare
MMP_RS04015 -1.2 -1.6 hypothetical protein compare
MMP_RS03475 -1.2 -0.4 hypothetical protein compare
MMP_RS06660 -1.2 -4.7 glycosyltransferase family 4 protein compare
MMP_RS05940 -1.1 -2.6 corrinoid protein compare
MMP_RS06885 -1.1 -1.1 50S ribosome-binding GTPase compare
MMP_RS03465 -1.1 -0.7 adenine phosphoribosyltransferase compare
MMP_RS05985 -1.1 -1.3 hypothetical protein compare
MMP_RS05285 -1.0 -3.6 MMPL family transporter compare
MMP_RS02280 -1.0 -0.5 DUF211 domain-containing protein compare
MMP_RS07130 -1.0 -3.3 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS07005 -1.0 -0.4 4Fe-4S binding protein compare
MMP_RS03960 -1.0 -0.5 hypothetical protein compare
MMP_RS03440 -1.0 -0.6 MoaD/ThiS family protein compare
MMP_RS02085 -1.0 -3.8 inosine/xanthosine triphosphatase compare
MMP_RS02830 -1.0 -4.1 DUF432 domain-containing protein compare
MMP_RS05795 -1.0 -1.3 redox-regulated ATPase YchF compare
MMP_RS03205 -1.0 -0.7 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS07125 -1.0 -1.4 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS03965 -0.9 -1.1 hypothetical protein compare
MMP_RS01950 -0.9 -4.1 hypothetical protein compare
MMP_RS00895 -0.9 -1.4 hypothetical protein compare
MMP_RS08360 -0.9 -1.8 hypothetical protein compare
MMP_RS08235 -0.9 -3.0 hypothetical protein compare
MMP_RS03095 -0.9 -2.3 diphthine synthase compare
MMP_RS07525 -0.9 -2.2 4Fe-4S binding protein compare
MMP_RS04585 -0.9 -2.4 AIR synthase related protein compare
MMP_RS04480 -0.9 -5.8 lysine 2 3-aminomutase compare
MMP_RS01840 -0.9 -3.4 TIGR00289 family protein compare
MMP_RS00050 -0.9 -3.0 AarF/UbiB family protein compare
MMP_RS05295 -0.9 -3.0 minichromosome maintenance protein MCM compare
MMP_RS00685 -0.9 -1.3 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01790 -0.9 -3.0 restriction endonuclease compare
MMP_RS01460 -0.8 -1.7 hypothetical protein compare
MMP_RS05545 -0.8 -2.2 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS01380 -0.8 -1.1 PHP domain-containing protein compare
MMP_RS02780 -0.8 -3.9 hypothetical protein compare
MMP_RS03130 -0.8 -2.0 hypothetical protein compare
MMP_RS05925 -0.8 -1.0 small nuclear ribonucleoprotein compare
MMP_RS07425 -0.8 -1.5 GTP-binding protein compare
MMP_RS07840 -0.8 -1.4 ribonuclease III compare
MMP_RS04055 -0.8 -0.7 hypothetical protein compare
MMP_RS03035 -0.8 -1.0 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS00475 -0.8 -3.4 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS02020 -0.8 -1.7 gamma-glutamylcyclotransferase compare
MMP_RS07755 -0.8 -0.6 DUF555 domain-containing protein compare
MMP_RS08280 -0.8 -1.4 proteasome assembly chaperone family protein compare
MMP_RS06910 -0.8 -3.0 RlmF-related methyltransferase compare
MMP_RS07620 -0.8 -1.3 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS03485 -0.8 -1.4 TIGR00267 family protein compare
MMP_RS07955 -0.8 -1.7 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06725 -0.8 -1.6 hypothetical protein compare
MMP_RS04270 -0.8 -2.8 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS02825 -0.8 -3.7 mechanosensitive ion channel family protein compare
MMP_RS01110 -0.8 -1.7 FmdE family protein compare
MMP_RS02815 -0.8 -1.4 hypothetical protein compare
MMP_RS01335 -0.8 -0.8 prefoldin subunit beta compare
MMP_RS07380 -0.8 -0.5 transcription elongation factor Spt5 compare
MMP_RS01935 -0.7 -2.8 DUF58 domain-containing protein compare
MMP_RS05865 -0.7 -0.9 hypothetical protein compare
MMP_RS00945 -0.7 -0.7 PadR family transcriptional regulator compare
MMP_RS03490 -0.7 -0.7 DUF2115 domain-containing protein compare
MMP_RS00635 -0.7 -1.5 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS06320 -0.7 -2.2 hypothetical protein compare
MMP_RS01655 -0.7 -1.3 DsrE family protein compare
MMP_RS02915 -0.7 -1.1 amino acid ABC transporter permease compare
MMP_RS04995 -0.7 -3.1 hypothetical protein compare
MMP_RS05525 -0.7 -1.5 calcium/sodium antiporter compare
MMP_RS01635 -0.7 -2.8 thiamine pyrophosphate-dependent enzyme compare
MMP_RS06735 -0.7 -2.0 class I SAM-dependent rRNA methyltransferase compare
MMP_RS06140 -0.7 -1.3 radical SAM protein compare
MMP_RS05050 -0.7 -3.0 substrate-binding domain-containing protein compare
MMP_RS01225 -0.7 -1.7 DUF5379 domain-containing protein compare
MMP_RS07720 -0.7 -4.0 4Fe-4S binding protein compare
MMP_RS03590 -0.7 -2.0 METTL5 family protein compare
MMP_RS02175 -0.7 -0.4 DUF1611 domain-containing protein compare
MMP_RS01255 -0.7 -1.7 amino acid ABC transporter ATP-binding protein compare
MMP_RS01675 -0.7 -0.8 hypothetical protein compare
MMP_RS01180 -0.7 -0.8 XTP/dITP diphosphatase compare
MMP_RS01445 -0.7 -1.8 hypothetical protein compare
MMP_RS04625 -0.6 -2.8 DEAD/DEAH box helicase compare
MMP_RS08365 -0.6 -1.4 energy conserving hydrogenase EhbF compare
MMP_RS00620 -0.6 -1.7 4Fe-4S binding protein compare
MMP_RS00655 -0.6 -1.2 hypothetical protein compare
MMP_RS04875 -0.6 -1.4 energy-converting hydrogenase B subunit P compare
MMP_RS06150 -0.6 -2.9 hypothetical protein compare
MMP_RS00235 -0.6 -2.7 HDIG domain-containing protein conserved
MMP_RS00630 -0.6 -2.9 ECF transporter S component compare
MMP_RS03800 -0.6 -1.1 hypothetical protein compare
MMP_RS04670 -0.6 -2.5 selenouridine synthase SelU-like subunit compare
MMP_RS01945 -0.6 -2.0 DUF4350 domain-containing protein compare
MMP_RS08580 -0.6 -1.5 flagellin compare
MMP_RS08345 -0.6 -2.5 4Fe-4S binding protein compare
MMP_RS03245 -0.6 -1.6 DNA repair and recombination protein RadB compare
MMP_RS07835 -0.6 -2.0 TldD/PmbA family protein compare
MMP_RS01660 -0.6 -1.5 hypothetical protein compare
MMP_RS06300 -0.6 -2.4 ABC transporter substrate-binding protein compare
MMP_RS01150 -0.6 -2.1 aldo/keto reductase compare
MMP_RS03420 -0.6 -0.8 acetolactate synthase small subunit compare
MMP_RS01930 -0.6 -2.9 hypothetical protein compare
MMP_RS01980 -0.6 -2.9 trimeric intracellular cation channel family protein compare
MMP_RS05450 -0.6 -1.0 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS08285 -0.6 -1.9 serine/threonine protein kinase compare
MMP_RS01870 -0.6 -2.3 acyl-CoA dehydratase activase compare
MMP_RS07150 -0.6 -1.9 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS03870 -0.6 -1.5 purine NTPase compare
MMP_RS08690 -0.6 -1.9 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS04945 -0.6 -1.6 hypothetical protein compare
MMP_RS06970 -0.6 -2.4 ribosomal protein S18-alanine N-acetyltransferase compare
MMP_RS00930 -0.6 -1.8 ABC transporter permease compare
MMP_RS08990 -0.6 -1.8 hypothetical protein compare
MMP_RS05155 -0.5 -1.4 hypothetical protein compare
MMP_RS00535 -0.5 -1.2 TIGR00375 family protein compare
MMP_RS08225 -0.5 -2.1 RimK family alpha-L-glutamate ligase compare
MMP_RS01175 -0.5 -1.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS07530 -0.5 -2.5 4Fe-4S binding protein compare
MMP_RS03390 -0.5 -1.4 malate dehydrogenase compare
MMP_RS00900 -0.5 -0.7 50S ribosomal protein L39e compare
MMP_RS02625 -0.5 -2.0 ribonuclease H-like domain-containing protein compare
MMP_RS00710 -0.5 -1.2 hypothetical protein compare
MMP_RS05490 -0.5 -1.3 IMPACT family protein compare
MMP_RS00400 -0.5 -1.5 tributyrin esterase compare
MMP_RS06325 -0.5 -0.4 hypothetical protein compare
MMP_RS03840 -0.5 -1.2 hypothetical protein compare
MMP_RS06610 -0.5 -0.6 DUF2334 domain-containing protein compare
MMP_RS01495 -0.5 -1.9 TraB/GumN family protein compare
MMP_RS08290 -0.5 -2.1 DNA-binding protein Alba compare
MMP_RS01490 -0.5 -1.5 tetratricopeptide repeat protein compare
MMP_RS06680 -0.5 -2.4 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS01750 -0.5 -2.1 DUF63 family protein compare


Specific Phenotypes

For 14 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis S2

For stress Sodium hypophosphite across organisms