Experiment set15S710 for Methanococcus maripaludis S2

Compare to:

Formate 50 mM hypophosphite

200 most important genes:

  gene name fitness t score description  
MMP_RS01915 -5.8 -11.8 DUF354 domain-containing protein compare
MMP_RS01970 -5.5 -16.2 TIGR04279 domain-containing protein compare
MMP_RS05920 -5.2 -1.6 50S ribosomal protein L37e compare
MMP_RS01920 -4.9 -16.9 glycosyltransferase family 2 protein compare
MMP_RS01910 -4.8 -11.7 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS01885 -4.7 -9.5 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01985 -4.7 -9.8 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS01955 -4.5 -4.3 hypothetical protein compare
MMP_RS01880 -4.3 -9.3 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01925 -4.1 -11.1 DUF1616 domain-containing protein compare
MMP_RS08790 -4.0 -3.7 translation initiation factor IF-2 subunit alpha compare
MMP_RS02355 -4.0 -6.5 30S ribosomal protein S27ae compare
MMP_RS08720 -3.9 -3.6 4Fe-4S binding protein compare
MMP_RS06700 -3.8 -16.2 hypothetical protein compare
MMP_RS06350 -3.6 -9.1 HesA/MoeB/ThiF family protein compare
MMP_RS01875 -3.6 -9.8 N-acetyltransferase compare
MMP_RS01900 -3.6 -18.2 hypothetical protein compare
MMP_RS08300 -3.5 -2.7 metal-sulfur cluster assembly factor compare
MMP_RS08635 -3.5 -3.9 UbiA family prenyltransferase compare
MMP_RS07005 -3.5 -1.4 4Fe-4S binding protein compare
MMP_RS01175 -3.4 -9.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS07635 -3.4 -9.5 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS01020 -3.4 -2.5 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS00300 -3.4 -1.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS01005 -3.4 -3.4 riboflavin synthase compare
MMP_RS06685 -3.3 -19.1 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS01905 -3.3 -15.1 glycosyltransferase compare
MMP_RS03015 -3.3 -14.5 GTP 3' 8-cyclase MoaA compare
MMP_RS06680 -3.2 -20.0 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06355 -3.2 -5.1 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01895 -3.2 -13.3 flippase compare
MMP_RS05515 -3.1 -14.4 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS04775 -3.1 -4.1 adenosylhomocysteinase compare
MMP_RS02165 -3.1 -10.2 tRNA-dihydrouridine synthase compare
MMP_RS06400 -3.1 -3.6 4Fe-4S binding protein compare
MMP_RS04585 -3.0 -12.5 AIR synthase related protein compare
MMP_RS01385 -3.0 -1.5 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS06345 -2.9 -18.7 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS02345 -2.9 -6.4 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS08435 -2.9 -3.4 Era-like GTP-binding protein compare
MMP_RS03315 -2.9 -1.7 ferrous iron transport protein A compare
MMP_RS01610 -2.9 -4.4 hypothetical protein compare
MMP_RS06295 -2.9 -10.6 methanogenesis marker 14 protein compare
MMP_RS08210 -2.9 -2.6 phosphatidylglycerophosphatase A compare
MMP_RS04720 -2.8 -3.9 DedA family protein compare
MMP_RS03640 -2.8 -5.7 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS04780 -2.8 -4.1 ribonuclease P compare
MMP_RS02800 -2.8 -7.4 nucleotidyltransferase domain-containing protein compare
MMP_RS05640 -2.8 -6.2 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS01890 -2.8 -4.6 nucleotide sugar dehydrogenase compare
MMP_RS06670 -2.8 -6.5 glucose-6-phosphate isomerase compare
MMP_RS06310 -2.8 -2.9 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS07075 -2.8 -5.3 phosphomannomutase/phosphoglucomutase compare
MMP_RS03025 -2.8 -8.1 molybdenum cofactor guanylyltransferase compare
MMP_RS01960 -2.7 -1.1 hypothetical protein compare
MMP_RS01220 -2.7 -12.7 hypothetical protein compare
MMP_RS02195 -2.7 -6.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS01830 -2.7 -3.0 tRNA-Val compare
MMP_RS07380 -2.7 -4.2 transcription elongation factor Spt5 compare
MMP_RS01500 -2.6 -3.7 CBS domain-containing protein compare
MMP_RS00335 -2.5 -9.2 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS03035 -2.5 -6.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS00685 -2.5 -6.3 2-phospho-L-lactate guanylyltransferase compare
MMP_RS02010 -2.5 -15.8 PHP domain-containing protein compare
MMP_RS07445 -2.5 -5.5 helix-turn-helix domain-containing protein compare
MMP_RS08070 -2.5 -9.3 DUF2096 domain-containing protein compare
MMP_RS08820 -2.5 -10.8 hypothetical protein compare
MMP_RS00750 -2.5 -5.1 fumarate hydratase compare
MMP_RS03700 -2.4 -12.3 sodium:proton antiporter compare
MMP_RS00120 -2.4 -10.5 LysR family transcriptional regulator compare
MMP_RS00305 -2.4 -2.7 phosphoribosyl-ATP diphosphatase compare
MMP_RS07730 -2.4 -3.1 pyruvate synthase subunit beta compare
MMP_RS04710 -2.4 -3.6 hypothetical protein compare
MMP_RS03305 -2.4 -14.8 winged helix-turn-helix domain-containing protein compare
MMP_RS03600 -2.4 -3.6 triose-phosphate isomerase compare
MMP_RS07605 -2.3 -6.1 diadenylate cyclase compare
MMP_RS05545 -2.3 -9.6 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02145 -2.3 -8.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS07575 -2.3 -5.5 RNA ligase partner protein compare
MMP_RS08745 -2.2 -7.2 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS00895 -2.2 -5.6 hypothetical protein compare
MMP_RS06200 -2.2 -12.5 M24 family metallopeptidase compare
MMP_RS04890 -2.2 -1.7 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS06715 -2.2 -17.0 cache domain-containing protein compare
MMP_RS05550 -2.2 -1.6 cation:proton antiporter compare
MMP_RS06720 -2.2 -14.1 response regulator transcription factor compare
MMP_RS01225 -2.2 -5.7 DUF5379 domain-containing protein compare
MMP_RS01545 -2.1 -2.4 CBS domain-containing protein compare
MMP_RS06270 -2.1 -9.4 TIGR00300 family protein compare
MMP_RS02280 -2.1 -2.0 DUF211 domain-containing protein compare
MMP_RS06625 -2.1 -4.8 DNA primase compare
MMP_RS08715 -2.1 -3.2 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07555 -2.1 -1.4 monovalent cation/H+ antiporter subunit E compare
MMP_RS01800 -2.1 -4.9 TIGR00303 family protein compare
MMP_RS01265 -2.1 -3.4 hypothetical protein compare
MMP_RS03580 -2.1 -5.7 signal recognition particle-docking protein FtsY compare
MMP_RS01725 -2.1 -5.9 class I SAM-dependent methyltransferase family protein compare
MMP_RS05765 -2.0 -9.1 M42 family metallopeptidase compare
MMP_RS06925 -2.0 -3.3 ribonuclease VapC4 compare
MMP_RS05345 -2.0 -7.3 hypothetical protein compare
MMP_RS05845 -2.0 -3.0 tRNA-intron lyase compare
MMP_RS02135 -2.0 -5.5 DUF5612 domain-containing protein compare
MMP_RS08785 -2.0 -2.1 RNA-protein complex protein Nop10 compare
MMP_RS06475 -2.0 -4.4 FAD-dependent oxidoreductase compare
MMP_RS06885 -2.0 -5.4 50S ribosome-binding GTPase compare
MMP_RS05250 -2.0 -3.2 NFYB/HAP3 family transcription factor subunit compare
MMP_RS06940 -2.0 -2.8 polyprenyl diphosphate synthase compare
MMP_RS05875 -2.0 -8.1 hydroxyethylthiazole kinase compare
MMP_RS06895 -1.9 -3.1 selenocysteine-specific translation elongation factor compare
MMP_RS01665 -1.9 -4.0 DUF2111 domain-containing protein compare
MMP_RS03140 -1.9 -12.5 hypothetical protein compare
MMP_RS07685 -1.9 -9.2 TIGR01212 family radical SAM protein compare
MMP_RS08650 -1.9 -3.8 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS03145 -1.9 -9.3 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS02340 -1.9 -1.8 DNA-directed RNA polymerase subunit E'' compare
MMP_RS07750 -1.9 -4.1 DUF357 domain-containing protein compare
MMP_RS03445 -1.9 -2.1 methanogenesis marker 17 protein compare
MMP_RS07755 -1.9 -2.4 DUF555 domain-containing protein compare
MMP_RS05925 -1.9 -4.5 small nuclear ribonucleoprotein compare
MMP_RS07435 -1.8 -2.7 GMP synthase subunit A compare
MMP_RS00295 -1.8 -4.8 gamma carbonic anhydrase family protein compare
MMP_RS06315 -1.8 -1.8 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS06855 -1.8 -9.8 hypothetical protein compare
MMP_RS01755 -1.8 -1.9 DUF2097 domain-containing protein compare
MMP_RS05430 -1.8 -4.3 TIGR00288 family NYN domain-containing protein compare
MMP_RS09020 -1.8 -1.7 hypothetical protein compare
MMP_RS05540 -1.8 -3.6 hypothetical protein compare
MMP_RS05555 -1.8 -2.2 DUF4040 domain-containing protein compare
MMP_RS03155 -1.8 -10.0 precorrin-6A reductase compare
MMP_RS06840 -1.8 -1.9 DNA-directed RNA polymerase subunit N compare
MMP_RS04685 -1.8 -3.9 DUF126 domain-containing protein compare
MMP_RS08075 -1.8 -6.8 DUF749 domain-containing protein compare
MMP_RS06730 -1.8 -2.7 phosphopantothenate/pantothenate synthetase compare
MMP_RS06120 -1.8 -3.5 UPF0147 family protein compare
MMP_RS06215 -1.8 -5.6 30S ribosomal protein S6e compare
MMP_RS03555 -1.7 -8.8 transcriptional regulator compare
MMP_RS07580 -1.7 -5.7 DUF356 domain-containing protein compare
MMP_RS07845 -1.7 -4.5 LL-diaminopimelate aminotransferase compare
MMP_RS05445 -1.7 -8.2 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS06630 -1.7 -1.6 UPF0058 family protein compare
MMP_RS00110 -1.7 -2.9 hypothetical protein compare
MMP_RS00810 -1.7 -7.9 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS08645 -1.7 -7.3 UPF0179 family protein compare
MMP_RS01325 -1.6 -2.7 dihydroneopterin aldolase family protein compare
MMP_RS01975 -1.6 -9.9 hypothetical protein compare
MMP_RS03400 -1.6 -4.2 archease compare
MMP_RS08320 -1.6 -8.5 molybdopterin molybdotransferase MoeA compare
MMP_RS00985 -1.6 -8.0 CDC48 family AAA ATPase compare
MMP_RS05425 -1.6 -6.0 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS02240 -1.6 -4.4 methanogenesis marker 7 protein compare
MMP_RS03435 -1.6 -2.6 ketol-acid reductoisomerase compare
MMP_RS06705 -1.6 -5.7 formate/nitrite transporter family protein compare
MMP_RS00130 -1.6 -2.2 nickel-responsive transcriptional regulator NikR compare
MMP_RS01940 -1.6 -5.4 MoxR family ATPase compare
MMP_RS02230 -1.6 -10.7 sodium-dependent transporter compare
MMP_RS03960 -1.6 -1.7 hypothetical protein compare
MMP_RS00720 -1.5 -10.8 metal-dependent hydrolase compare
MMP_RS02245 -1.5 -5.3 hypothetical protein compare
MMP_RS00695 -1.5 -1.3 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS05265 -1.5 -2.3 2-isopropylmalate synthase compare
MMP_RS06105 -1.5 -8.3 hydrogenase maturation peptidase HycI compare
MMP_RS03250 -1.5 -3.5 MJ1244 family protein compare
MMP_RS00320 -1.5 -3.3 class I SAM-dependent methyltransferase compare
MMP_RS06230 -1.5 -4.0 helix-turn-helix domain-containing protein compare
MMP_RS07735 -1.4 -1.2 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS00115 -1.4 -9.9 radical SAM protein compare
MMP_RS08460 -1.4 -3.3 proteasome-activating nucleotidase compare
MMP_RS04500 -1.4 -11.9 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS06285 -1.4 -1.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS03205 -1.4 -2.3 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS02875 -1.4 -7.9 chorismate pyruvate-lyase family protein compare
MMP_RS08445 -1.4 -5.7 DUF2099 family protein compare
MMP_RS03475 -1.4 -1.0 hypothetical protein compare
MMP_RS08100 -1.3 -9.3 8-amino-7-oxononanoate synthase compare
MMP_RS01250 -1.3 -7.8 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS04870 -1.3 -6.1 TIGR02253 family HAD-type hydrolase compare
MMP_RS08330 -1.3 -6.5 NADH-quinone oxidoreductase subunit H compare
MMP_RS06020 -1.3 -4.6 archaeoflavoprotein AfpA compare
MMP_RS01795 -1.3 -2.1 methanogenesis marker 6 protein compare
MMP_RS00060 -1.3 -1.4 3-dehydroquinate synthase II compare
MMP_RS06130 -1.3 -3.8 peptidylprolyl isomerase compare
MMP_RS03095 -1.3 -6.1 diphthine synthase compare
MMP_RS04955 -1.3 -4.9 DNA topoisomerase I compare
MMP_RS06370 -1.3 -5.6 biotin synthase BioB compare
MMP_RS02885 -1.2 -10.5 molybdopterin biosynthesis protein compare
MMP_RS07525 -1.2 -6.3 4Fe-4S binding protein compare
MMP_RS07390 -1.2 -2.3 cell division protein FtsZ compare
MMP_RS07600 -1.2 -3.3 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS07420 -1.2 -5.3 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01365 -1.2 -2.5 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07955 -1.2 -3.8 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS07200 -1.2 -6.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS08095 -1.2 -7.2 dethiobiotin synthase compare
MMP_RS06340 -1.2 -7.6 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS08690 -1.1 -6.6 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS05930 -1.1 -2.3 3-isopropylmalate dehydratase large subunit compare
MMP_RS06535 -1.1 -5.0 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS00290 -1.1 -6.3 hypothetical protein compare
MMP_RS00235 -1.1 -7.9 HDIG domain-containing protein conserved
MMP_RS05815 -1.1 -1.5 NOL1/NOP2/sun family putative RNA methylase compare


Specific Phenotypes

For 1 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis S2

For stress Sodium hypophosphite across organisms