Experiment set15S709 for Methanococcus maripaludis S2

Compare to:

Formate 50 mM hypophosphite

200 most important genes:

  gene name fitness t score description  
MMP_RS01970 -6.1 -15.7 TIGR04279 domain-containing protein compare
MMP_RS01175 -6.0 -5.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS01920 -5.4 -19.0 glycosyltransferase family 2 protein compare
MMP_RS08720 -5.4 -3.7 4Fe-4S binding protein compare
MMP_RS00305 -5.4 -3.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS07005 -5.2 -1.4 4Fe-4S binding protein compare
MMP_RS01915 -5.2 -14.6 DUF354 domain-containing protein compare
MMP_RS01885 -5.0 -8.4 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01985 -4.9 -10.5 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS01910 -4.8 -11.5 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS04780 -4.6 -5.8 ribonuclease P compare
MMP_RS06700 -4.5 -16.4 hypothetical protein compare
MMP_RS02355 -4.4 -5.3 30S ribosomal protein S27ae compare
MMP_RS07635 -4.3 -9.2 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06350 -4.3 -9.2 HesA/MoeB/ThiF family protein compare
MMP_RS01955 -4.3 -4.1 hypothetical protein compare
MMP_RS06680 -4.2 -21.6 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS01880 -4.1 -7.0 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS03015 -4.1 -10.5 GTP 3' 8-cyclase MoaA compare
MMP_RS06345 -4.1 -18.4 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS02280 -4.1 -1.9 DUF211 domain-containing protein compare
MMP_RS01220 -3.9 -12.7 hypothetical protein compare
MMP_RS01890 -3.9 -5.9 nucleotide sugar dehydrogenase compare
MMP_RS01610 -3.9 -5.5 hypothetical protein compare
MMP_RS06685 -3.8 -21.9 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS05515 -3.8 -10.9 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS00695 -3.7 -1.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01925 -3.7 -10.8 DUF1616 domain-containing protein compare
MMP_RS04585 -3.6 -12.8 AIR synthase related protein compare
MMP_RS06355 -3.6 -4.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01900 -3.6 -17.7 hypothetical protein compare
MMP_RS05845 -3.5 -2.6 tRNA-intron lyase compare
MMP_RS02165 -3.5 -11.2 tRNA-dihydrouridine synthase compare
MMP_RS01830 -3.5 -2.7 tRNA-Val compare
MMP_RS08070 -3.4 -11.2 DUF2096 domain-containing protein compare
MMP_RS02800 -3.3 -8.3 nucleotidyltransferase domain-containing protein compare
MMP_RS01905 -3.3 -13.3 glycosyltransferase compare
MMP_RS02345 -3.3 -6.1 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06715 -3.3 -20.3 cache domain-containing protein compare
MMP_RS06895 -3.3 -3.7 selenocysteine-specific translation elongation factor compare
MMP_RS03600 -3.3 -3.6 triose-phosphate isomerase compare
MMP_RS05555 -3.2 -2.2 DUF4040 domain-containing protein compare
MMP_RS00110 -3.2 -3.2 hypothetical protein compare
MMP_RS03315 -3.2 -2.3 ferrous iron transport protein A compare
MMP_RS06925 -3.2 -4.5 ribonuclease VapC4 compare
MMP_RS08635 -3.2 -3.1 UbiA family prenyltransferase compare
MMP_RS00685 -3.1 -5.3 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01800 -3.1 -6.9 TIGR00303 family protein compare
MMP_RS06720 -3.1 -17.2 response regulator transcription factor compare
MMP_RS08300 -3.1 -2.4 metal-sulfur cluster assembly factor compare
MMP_RS01875 -3.1 -9.7 N-acetyltransferase compare
MMP_RS07075 -3.1 -5.3 phosphomannomutase/phosphoglucomutase compare
MMP_RS06475 -3.1 -7.1 FAD-dependent oxidoreductase compare
MMP_RS01725 -3.1 -6.7 class I SAM-dependent methyltransferase family protein compare
MMP_RS07380 -3.1 -3.4 transcription elongation factor Spt5 compare
MMP_RS06670 -3.1 -5.8 glucose-6-phosphate isomerase compare
MMP_RS06200 -3.0 -11.6 M24 family metallopeptidase compare
MMP_RS03025 -3.0 -7.4 molybdenum cofactor guanylyltransferase compare
MMP_RS04720 -3.0 -3.7 DedA family protein compare
MMP_RS01385 -3.0 -1.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS05545 -3.0 -10.7 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS07445 -2.9 -5.7 helix-turn-helix domain-containing protein compare
MMP_RS00120 -2.9 -7.2 LysR family transcriptional regulator compare
MMP_RS01895 -2.9 -11.2 flippase compare
MMP_RS01005 -2.9 -3.1 riboflavin synthase compare
MMP_RS06315 -2.9 -1.9 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08790 -2.9 -3.2 translation initiation factor IF-2 subunit alpha compare
MMP_RS01755 -2.9 -2.3 DUF2097 domain-containing protein compare
MMP_RS02010 -2.9 -11.5 PHP domain-containing protein compare
MMP_RS06285 -2.8 -4.5 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS00300 -2.8 -1.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS01500 -2.8 -3.6 CBS domain-containing protein compare
MMP_RS07730 -2.8 -2.8 pyruvate synthase subunit beta compare
MMP_RS06705 -2.8 -10.9 formate/nitrite transporter family protein compare
MMP_RS07845 -2.7 -4.3 LL-diaminopimelate aminotransferase compare
MMP_RS00295 -2.7 -4.8 gamma carbonic anhydrase family protein compare
MMP_RS06270 -2.7 -8.2 TIGR00300 family protein compare
MMP_RS09020 -2.7 -2.2 hypothetical protein compare
MMP_RS01225 -2.7 -7.5 DUF5379 domain-containing protein compare
MMP_RS04685 -2.7 -5.0 DUF126 domain-containing protein compare
MMP_RS01960 -2.7 -1.0 hypothetical protein compare
MMP_RS07735 -2.7 -1.1 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06730 -2.6 -2.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS05640 -2.6 -6.2 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS00750 -2.6 -3.2 fumarate hydratase compare
MMP_RS06630 -2.6 -1.8 UPF0058 family protein compare
MMP_RS07575 -2.5 -5.7 RNA ligase partner protein compare
MMP_RS03305 -2.5 -13.8 winged helix-turn-helix domain-containing protein compare
MMP_RS06295 -2.5 -9.6 methanogenesis marker 14 protein compare
MMP_RS03435 -2.5 -2.7 ketol-acid reductoisomerase compare
MMP_RS02135 -2.5 -6.5 DUF5612 domain-containing protein compare
MMP_RS05550 -2.5 -1.5 cation:proton antiporter compare
MMP_RS02195 -2.5 -4.8 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS05765 -2.5 -9.7 M42 family metallopeptidase compare
MMP_RS03640 -2.4 -5.5 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS07555 -2.4 -1.3 monovalent cation/H+ antiporter subunit E compare
MMP_RS06885 -2.4 -3.9 50S ribosome-binding GTPase compare
MMP_RS05345 -2.4 -9.2 hypothetical protein compare
MMP_RS03700 -2.4 -8.0 sodium:proton antiporter compare
MMP_RS02340 -2.4 -3.4 DNA-directed RNA polymerase subunit E'' compare
MMP_RS00895 -2.4 -5.7 hypothetical protein compare
MMP_RS08210 -2.4 -4.7 phosphatidylglycerophosphatase A compare
MMP_RS03960 -2.4 -1.8 hypothetical protein compare
MMP_RS06120 -2.4 -3.3 UPF0147 family protein compare
MMP_RS07605 -2.4 -6.1 diadenylate cyclase compare
MMP_RS03145 -2.3 -8.2 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS01545 -2.3 -2.2 CBS domain-containing protein compare
MMP_RS04775 -2.3 -3.9 adenosylhomocysteinase compare
MMP_RS08820 -2.3 -8.1 hypothetical protein compare
MMP_RS05250 -2.3 -3.3 NFYB/HAP3 family transcription factor subunit compare
MMP_RS02885 -2.3 -15.9 molybdopterin biosynthesis protein compare
MMP_RS07435 -2.3 -3.2 GMP synthase subunit A compare
MMP_RS01020 -2.3 -2.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS00335 -2.3 -6.6 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS03475 -2.2 -1.2 hypothetical protein compare
MMP_RS08320 -2.2 -11.1 molybdopterin molybdotransferase MoeA compare
MMP_RS08715 -2.2 -3.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06020 -2.2 -4.8 archaeoflavoprotein AfpA compare
MMP_RS05875 -2.2 -6.6 hydroxyethylthiazole kinase compare
MMP_RS03400 -2.2 -3.6 archease compare
MMP_RS03140 -2.2 -13.8 hypothetical protein compare
MMP_RS06400 -2.2 -3.1 4Fe-4S binding protein compare
MMP_RS02145 -2.1 -7.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS05920 -2.1 -1.1 50S ribosomal protein L37e compare
MMP_RS08460 -2.1 -4.3 proteasome-activating nucleotidase compare
MMP_RS05425 -2.1 -6.3 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS08075 -2.1 -6.8 DUF749 domain-containing protein compare
MMP_RS03035 -2.1 -4.6 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS06855 -2.1 -12.0 hypothetical protein compare
MMP_RS00320 -2.0 -2.9 class I SAM-dependent methyltransferase compare
MMP_RS05540 -2.0 -2.4 hypothetical protein compare
MMP_RS00810 -2.0 -10.5 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07600 -2.0 -4.0 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06310 -2.0 -3.4 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS08745 -2.0 -6.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07580 -2.0 -3.5 DUF356 domain-containing protein compare
MMP_RS02240 -1.9 -5.8 methanogenesis marker 7 protein compare
MMP_RS04710 -1.9 -2.7 hypothetical protein compare
MMP_RS04615 -1.9 -3.7 PDGLE domain-containing protein compare
MMP_RS07545 -1.9 -1.6 HTH domain-containing protein compare
MMP_RS08645 -1.9 -8.5 UPF0179 family protein compare
MMP_RS05430 -1.9 -4.0 TIGR00288 family NYN domain-containing protein compare
MMP_RS07630 -1.9 -2.0 ATP-binding cassette domain-containing protein compare
MMP_RS08435 -1.9 -3.7 Era-like GTP-binding protein compare
MMP_RS03555 -1.9 -6.8 transcriptional regulator compare
MMP_RS07685 -1.9 -11.4 TIGR01212 family radical SAM protein compare
MMP_RS00985 -1.8 -7.5 CDC48 family AAA ATPase compare
MMP_RS06625 -1.8 -2.5 DNA primase compare
MMP_RS05925 -1.8 -4.6 small nuclear ribonucleoprotein compare
MMP_RS05445 -1.8 -10.2 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS03155 -1.8 -7.4 precorrin-6A reductase compare
MMP_RS02875 -1.8 -7.8 chorismate pyruvate-lyase family protein compare
MMP_RS01795 -1.8 -2.5 methanogenesis marker 6 protein compare
MMP_RS06105 -1.8 -9.5 hydrogenase maturation peptidase HycI compare
MMP_RS06840 -1.8 -1.7 DNA-directed RNA polymerase subunit N compare
MMP_RS02245 -1.8 -5.3 hypothetical protein compare
MMP_RS01665 -1.7 -4.4 DUF2111 domain-containing protein compare
MMP_RS06980 -1.7 -9.0 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS06940 -1.7 -3.3 polyprenyl diphosphate synthase compare
MMP_RS08650 -1.7 -3.5 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01325 -1.7 -3.3 dihydroneopterin aldolase family protein compare
MMP_RS01265 -1.6 -2.6 hypothetical protein compare
MMP_RS01940 -1.6 -4.1 MoxR family ATPase compare
MMP_RS00115 -1.6 -10.6 radical SAM protein compare
MMP_RS02230 -1.6 -12.7 sodium-dependent transporter compare
MMP_RS03205 -1.6 -2.0 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS03250 -1.6 -2.9 MJ1244 family protein compare
MMP_RS06130 -1.5 -4.3 peptidylprolyl isomerase compare
MMP_RS01975 -1.5 -8.8 hypothetical protein compare
MMP_RS06860 -1.5 -2.3 4Fe-4S binding protein compare
MMP_RS00290 -1.5 -8.1 hypothetical protein compare
MMP_RS03095 -1.5 -8.0 diphthine synthase compare
MMP_RS03445 -1.5 -1.7 methanogenesis marker 17 protein compare
MMP_RS04875 -1.5 -6.7 energy-converting hydrogenase B subunit P compare
MMP_RS07750 -1.5 -4.5 DUF357 domain-containing protein compare
MMP_RS08365 -1.4 -5.4 energy conserving hydrogenase EhbF compare
MMP_RS06215 -1.4 -4.4 30S ribosomal protein S6e compare
MMP_RS08360 -1.4 -4.6 hypothetical protein compare
MMP_RS04500 -1.4 -10.4 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS07755 -1.4 -1.4 DUF555 domain-containing protein compare
MMP_RS04870 -1.4 -4.9 TIGR02253 family HAD-type hydrolase compare
MMP_RS08335 -1.4 -6.6 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS00720 -1.4 -8.5 metal-dependent hydrolase compare
MMP_RS06540 -1.4 -4.0 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS03580 -1.4 -3.6 signal recognition particle-docking protein FtsY compare
MMP_RS01250 -1.4 -4.9 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS06230 -1.3 -1.8 helix-turn-helix domain-containing protein compare
MMP_RS08095 -1.3 -6.7 dethiobiotin synthase compare
MMP_RS08100 -1.3 -5.9 8-amino-7-oxononanoate synthase compare
MMP_RS08440 -1.3 -4.5 cell division protein SepF compare
MMP_RS04955 -1.3 -4.5 DNA topoisomerase I compare
MMP_RS00515 -1.3 -1.4 DUF655 domain-containing protein compare
MMP_RS08330 -1.3 -4.8 NADH-quinone oxidoreductase subunit H compare
MMP_RS06865 -1.3 -1.1 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS02880 -1.3 -4.1 AmmeMemoRadiSam system radical SAM enzyme compare
MMP_RS05245 -1.3 -8.0 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS07525 -1.3 -5.3 4Fe-4S binding protein compare
MMP_RS00130 -1.3 -1.8 nickel-responsive transcriptional regulator NikR compare
MMP_RS02130 -1.3 -3.8 zinc metalloprotease HtpX compare
MMP_RS06340 -1.3 -6.9 phosphoadenosine phosphosulfate reductase family protein compare


Specific Phenotypes

For 2 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis S2

For stress Sodium hypophosphite across organisms