Experiment set15S709 for Methanococcus maripaludis S2

Compare to:

Formate 50 mM hypophosphite

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS07850 +1.2 4.7 prephenate dehydratase compare
MMP_RS07115 +0.8 5.8 MBL fold metallo-hydrolase compare
MMP_RS08855 +0.7 5.6 hypothetical protein compare
MMP_RS03215 +0.7 5.1 MBL fold metallo-hydrolase compare
MMP_RS07120 +0.7 5.3 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS06975 +0.7 2.0 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07135 +0.7 4.1 coenzyme F420 hydrogenase subunit beta compare
MMP_RS07345 +0.7 3.7 glycine synthesis protein GlyXL (from data) compare
MMP_RS05580 +0.6 5.8 glycosyltransferase compare
MMP_RS07880 +0.6 5.2 AAA family ATPase compare
MMP_RS06555 +0.6 2.8 cupin domain-containing protein compare
MMP_RS07890 +0.6 2.7 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS01270 +0.6 5.4 prepilin peptidase compare
MMP_RS08225 +0.6 4.6 RimK family alpha-L-glutamate ligase compare
MMP_RS01290 +0.6 4.9 class III signal peptide-containing protein compare
MMP_RS08675 +0.6 2.9 class III signal peptide-containing protein compare
MMP_RS01435 +0.6 3.5 DMT family transporter compare
MMP_RS01310 +0.6 4.9 hypothetical protein compare
MMP_RS08310 +0.6 2.0 TMEM165/GDT1 family protein compare
MMP_RS08760 +0.6 2.3 hypothetical protein compare
MMP_RS01430 +0.5 4.5 mechanosensitive ion channel family protein compare
MMP_RS02475 +0.5 1.6 hypothetical protein compare
MMP_RS06485 +0.5 1.0 zinc ribbon domain-containing protein compare
MMP_RS01285 +0.5 4.6 hypothetical protein compare
MMP_RS01275 +0.5 3.9 class III signal peptide-containing protein compare
MMP_RS05985 +0.5 2.2 hypothetical protein compare
MMP_RS00655 +0.5 3.0 hypothetical protein compare
MMP_RS07680 +0.5 3.6 DUF366 family protein compare
MMP_RS07650 +0.5 4.6 TldD/PmbA family protein compare
MMP_RS05355 +0.5 0.9 hypothetical protein compare
MMP_RS01280 +0.5 4.5 DUF515 domain-containing protein compare
MMP_RS07130 +0.5 3.8 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS05975 +0.5 1.5 hypothetical protein compare
MMP_RS07835 +0.5 2.6 TldD/PmbA family protein compare
MMP_RS07330 +0.5 4.3 membrane protein compare
MMP_RS01305 +0.5 4.4 hypothetical protein compare
MMP_RS01295 +0.5 3.9 hypothetical protein compare
MMP_RS00240 +0.5 4.0 type II secretion system F family protein compare
MMP_RS05635 +0.5 3.7 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS03465 +0.5 1.1 adenine phosphoribosyltransferase compare
MMP_RS00250 +0.5 4.2 Flp pilus assembly complex ATPase component TadA compare
MMP_RS03420 +0.5 2.4 acetolactate synthase small subunit compare
MMP_RS01655 +0.5 2.7 DsrE family protein compare
MMP_RS00245 +0.5 4.2 type II secretion system F family protein compare
MMP_RS04145 +0.4 1.4 hypothetical protein compare
MMP_RS02960 +0.4 3.2 class I SAM-dependent methyltransferase family protein compare
MMP_RS03895 +0.4 2.3 hypothetical protein compare
MMP_RS06900 +0.4 1.4 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS02605 +0.4 0.7 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS05955 +0.4 1.6 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS08640 +0.4 3.3 TIM barrel protein compare
MMP_RS01315 +0.4 3.7 DUF2341 domain-containing protein compare
MMP_RS07125 +0.4 1.9 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS09055 +0.4 0.8 CAP domain-containing protein compare
MMP_RS08570 +0.4 2.8 coenzyme F420-0:L-glutamate ligase compare
MMP_RS07970 +0.4 1.6 hypothetical protein compare
MMP_RS08390 +0.4 2.1 DUF5400 domain-containing protein compare
MMP_RS06015 +0.4 2.5 flavodoxin family protein compare
MMP_RS05965 +0.4 2.0 carboxymuconolactone decarboxylase family protein compare
MMP_RS08830 +0.4 1.9 GTP-binding protein compare
MMP_RS01155 +0.4 2.2 XRE family transcriptional regulator compare
MMP_RS06335 +0.4 2.6 HAD family hydrolase compare
MMP_RS05990 +0.4 2.1 DsrE family protein compare
MMP_RS08160 +0.4 2.1 EamA family transporter compare
MMP_RS08265 +0.4 2.0 rubrerythrin compare
MMP_RS07155 +0.3 2.9 MFS transporter compare
MMP_RS06520 +0.3 2.1 DUF1786 domain-containing protein compare
MMP_RS08245 +0.3 2.7 DUF4013 domain-containing protein compare
MMP_RS01675 +0.3 1.0 hypothetical protein compare
MMP_RS03300 +0.3 0.4 TOBE domain-containing protein compare
MMP_RS08080 +0.3 2.8 YchF/TatD family DNA exonuclease compare
MMP_RS08480 +0.3 2.7 molybdate ABC transporter substrate-binding protein compare
MMP_RS04790 +0.3 2.3 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS09045 +0.3 2.8 class III signal peptide-containing protein compare
MMP_RS08580 +0.3 1.8 flagellin compare
MMP_RS02455 +0.3 2.7 hypothetical protein compare
MMP_RS08405 +0.3 2.5 MFS transporter compare
MMP_RS03910 +0.3 1.3 hypothetical protein compare
MMP_RS08275 +0.3 2.4 hypothetical protein compare
MMP_RS08325 +0.3 2.3 hypothetical protein compare
MMP_RS02595 +0.3 0.7 putative zinc-binding protein compare
MMP_RS00570 +0.3 1.0 protein-L-isoaspartate O-methyltransferase compare
MMP_RS08500 +0.3 1.7 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS08700 +0.3 1.9 hypothetical protein compare
MMP_RS07570 +0.3 2.2 nucleotidyltransferase family protein compare
MMP_RS04610 +0.3 1.2 Dabb family protein compare
MMP_RS07775 +0.3 2.1 alanine dehydrogenase compare
MMP_RS06550 +0.3 2.1 AMP-binding protein compare
MMP_RS01630 +0.3 1.8 N-glycosylase/DNA lyase compare
MMP_RS08205 +0.3 2.2 stage II sporulation protein M compare
MMP_RS08410 +0.3 1.8 DUF169 domain-containing protein compare
MMP_RS07590 +0.3 2.2 hypothetical protein compare
MMP_RS06760 +0.3 1.5 hypothetical protein compare
MMP_RS01790 +0.3 1.9 restriction endonuclease compare
MMP_RS02805 +0.3 0.6 HEPN domain-containing protein compare
MMP_RS05960 +0.3 2.3 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS02310 +0.3 0.9 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS02360 +0.3 1.7 hypothetical protein compare
MMP_RS01635 +0.3 1.4 thiamine pyrophosphate-dependent enzyme compare
MMP_RS08230 +0.3 1.9 50S ribosomal protein L11 methyltransferase compare
MMP_RS01660 +0.3 1.1 hypothetical protein compare
MMP_RS08755 +0.3 2.3 sodium:solute symporter family protein compare
MMP_RS00140 +0.3 1.0 DUF192 domain-containing protein compare
MMP_RS08490 +0.3 2.3 hypothetical protein compare
MMP_RS09060 +0.3 2.3 hypothetical protein compare
MMP_RS03280 +0.3 2.0 pyridoxamine 5'-phosphate oxidase family protein compare
MMP_RS02825 +0.2 2.1 mechanosensitive ion channel family protein compare
MMP_RS07640 +0.2 1.5 mechanosensitive ion channel family protein compare
MMP_RS03535 +0.2 1.3 helix-turn-helix transcriptional regulator compare
MMP_RS09050 +0.2 1.3 CAP domain-containing protein compare
MMP_RS08610 +0.2 2.2 flagellar protein F compare
MMP_RS07855 +0.2 1.9 class I SAM-dependent methyltransferase compare
MMP_RS01055 +0.2 1.5 hypothetical protein compare
MMP_RS02815 +0.2 1.2 hypothetical protein compare
MMP_RS08315 +0.2 0.9 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS05490 +0.2 1.3 IMPACT family protein compare
MMP_RS05905 +0.2 2.0 undecaprenyl-diphosphate phosphatase compare
MMP_RS07915 +0.2 1.7 DUF4870 domain-containing protein compare
MMP_RS05995 +0.2 2.0 FprA family A-type flavoprotein compare
MMP_RS01110 +0.2 1.7 FmdE family protein compare
MMP_RS01490 +0.2 1.5 tetratricopeptide repeat protein compare
MMP_RS05685 +0.2 1.6 winged helix-turn-helix domain-containing protein compare
MMP_RS02770 +0.2 1.3 hypothetical protein compare
MMP_RS00945 +0.2 0.6 PadR family transcriptional regulator compare
MMP_RS03800 +0.2 1.3 hypothetical protein compare
MMP_RS06560 +0.2 2.0 hypothetical protein compare
MMP_RS07895 +0.2 1.3 cytochrome c compare
MMP_RS09030 +0.2 1.6 hypothetical protein compare
MMP_RS00660 +0.2 1.9 alkaline phosphatase family protein compare
MMP_RS01570 +0.2 0.7 hypothetical protein compare
MMP_RS04795 +0.2 1.3 tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY compare
MMP_RS07800 +0.2 1.6 ATP-binding cassette domain-containing protein compare
MMP_RS01085 +0.2 0.7 hypothetical protein compare
MMP_RS08250 +0.2 1.7 pyruvate kinase compare
MMP_RS08750 +0.2 0.8 hypothetical protein compare
MMP_RS03965 +0.2 0.9 hypothetical protein compare
MMP_RS06050 +0.2 1.7 ZIP family metal transporter compare
MMP_RS01145 +0.2 1.7 ABC transporter ATP-binding protein compare
MMP_RS06480 +0.2 1.3 ABC transporter substrate-binding protein compare
MMP_RS06005 +0.2 1.1 heavy-metal-associated domain-containing protein compare
MMP_RS05130 +0.2 1.9 DUF2226 domain-containing protein compare
MMP_RS09025 +0.2 0.4 hypothetical protein compare
MMP_RS07550 +0.2 1.7 L-serine ammonia-lyase iron-sulfur-dependent subunit alpha compare
MMP_RS05865 +0.2 0.9 hypothetical protein compare
MMP_RS01870 +0.2 1.7 acyl-CoA dehydratase activase compare
MMP_RS02550 +0.2 1.6 helix-turn-helix transcriptional regulator compare
MMP_RS01300 +0.2 1.9 hypothetical protein compare
MMP_RS08995 +0.2 0.5 hypothetical protein compare
MMP_RS06465 +0.2 1.7 NERD domain-containing protein compare
MMP_RS00395 +0.2 0.6 MGMT family protein compare
MMP_RS05140 +0.2 0.7 helix-turn-helix transcriptional regulator compare
MMP_RS06490 +0.2 1.1 hypothetical protein compare
MMP_RS04785 +0.2 1.8 hypothetical protein compare
MMP_RS02685 +0.2 1.6 molybdate ABC transporter substrate-binding protein compare
MMP_RS08380 +0.2 1.5 phosphatase PAP2 family protein compare
MMP_RS08630 +0.2 1.2 archaellar assembly protein FlaJ compare
MMP_RS07770 +0.2 1.3 alanine racemase compare
MMP_RS03340 +0.2 0.3 ABC transporter ATP-binding protein compare
MMP_RS05715 +0.2 1.3 hypothetical protein compare
MMP_RS06300 +0.2 1.5 ABC transporter substrate-binding protein compare
MMP_RS07150 +0.2 1.0 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS06435 +0.2 1.3 CBS domain-containing protein compare
MMP_RS06150 +0.2 1.3 hypothetical protein compare
MMP_RS04740 +0.2 1.3 DUF473 domain-containing protein compare
MMP_RS00930 +0.2 1.3 ABC transporter permease compare
MMP_RS06000 +0.2 1.3 divalent-cation tolerance protein CutA compare
MMP_RS01185 +0.2 1.4 hypothetical protein compare
MMP_RS06115 +0.2 1.5 class II aldolase/adducin family protein compare
MMP_RS08665 +0.2 1.5 hypothetical protein compare
MMP_RS01775 +0.2 0.6 TIGR00297 family protein compare
MMP_RS07985 +0.2 1.5 nitroreductase family protein compare
MMP_RS08845 +0.2 1.5 archaellum operon transcriptional activator EarA family protein compare
MMP_RS08400 +0.2 0.7 MJ0307 family thioredoxin compare
MMP_RS08285 +0.2 1.3 serine/threonine protein kinase compare
MMP_RS08470 +0.2 1.3 ATP-binding cassette domain-containing protein compare
MMP_RS08555 +0.2 0.9 hypothetical protein compare
MMP_RS01770 +0.2 1.6 ATP-dependent endonuclease compare
MMP_RS03125 +0.2 0.9 cell division ATPase MinD compare
MMP_RS01135 +0.2 1.3 molybdate ABC transporter substrate-binding protein compare
MMP_RS07715 +0.2 1.2 YfcE family phosphodiesterase compare
MMP_RS03440 +0.2 0.3 MoaD/ThiS family protein compare
MMP_RS07085 +0.2 1.4 ribonuclease HII compare
MMP_RS03350 +0.2 0.7 winged helix-turn-helix domain-containing protein compare
MMP_RS04520 +0.2 0.8 nucleoside deaminase compare
MMP_RS06190 +0.2 1.2 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO compare
MMP_RS09065 +0.2 1.4 hypothetical protein compare
MMP_RS02740 +0.2 0.9 hypothetical protein compare
MMP_RS08980 +0.2 1.2 hypothetical protein compare
MMP_RS01195 +0.2 0.4 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS08085 +0.2 1.4 hypothetical protein compare
MMP_RS01115 +0.2 1.3 molybdopterin molybdotransferase MoeA compare
MMP_RS07100 +0.2 1.4 hypothetical protein compare
MMP_RS03740 +0.2 1.0 indolepyruvate oxidoreductase subunit beta compare
MMP_RS08475 +0.2 1.3 ABC transporter permease compare
MMP_RS01685 +0.2 0.7 indolepyruvate oxidoreductase subunit beta compare
MMP_RS03220 +0.2 0.7 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS06970 +0.2 1.3 ribosomal protein S18-alanine N-acetyltransferase compare
MMP_RS08235 +0.2 0.8 hypothetical protein compare
MMP_RS01125 +0.2 1.2 thioredoxin family protein compare
MMP_RS01095 +0.2 0.8 iron ABC transporter permease compare


Specific Phenotypes

For 2 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis S2

For stress Sodium hypophosphite across organisms