Experiment set15S707 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS07005		-5.2	-1.6	4Fe-4S binding protein
MMP_RS05920		-5.1	-1.5	50S ribosomal protein L37e
MMP_RS00695		-4.8	-2.1	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS06700		-4.8	-14.6	hypothetical protein
MMP_RS08720		-4.5	-3.1	4Fe-4S binding protein
MMP_RS01920		-4.2	-15.8	glycosyltransferase family 2 protein
MMP_RS01175		-4.2	-10.5	triphosphoribosyl-dephospho-CoA synthase
MMP_RS01915		-4.2	-16.5	DUF354 domain-containing protein
MMP_RS01985		-3.9	-11.2	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS06355		-3.9	-5.5	molybdenum cofactor biosynthesis protein MoaE
MMP_RS04585		-3.5	-11.6	AIR synthase related protein
MMP_RS01970		-3.5	-9.9	TIGR04279 domain-containing protein
MMP_RS02195		-3.5	-5.1	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS07435		-3.4	-3.5	GMP synthase subunit A
MMP_RS02280		-3.4	-2.1	DUF211 domain-containing protein
MMP_RS08715		-3.4	-3.4	formylmethanofuran dehydrogenase subunit B
MMP_RS03600		-3.2	-3.5	triose-phosphate isomerase
MMP_RS08790		-3.2	-3.9	translation initiation factor IF-2 subunit alpha
MMP_RS08210		-3.2	-2.5	phosphatidylglycerophosphatase A
MMP_RS09020		-3.2	-3.6	hypothetical protein
MMP_RS06350		-3.1	-9.6	HesA/MoeB/ThiF family protein
MMP_RS07635		-3.1	-10.0	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS01005		-3.0	-3.4	riboflavin synthase
MMP_RS02240		-3.0	-6.1	methanogenesis marker 7 protein
MMP_RS01755		-3.0	-2.1	DUF2097 domain-containing protein
MMP_RS06680		-3.0	-19.6	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS02900		-3.0	-1.3	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS06475		-2.9	-6.9	FAD-dependent oxidoreductase
MMP_RS00110		-2.9	-5.8	hypothetical protein
MMP_RS01385		-2.9	-1.5	imidazole glycerol phosphate synthase subunit HisH
MMP_RS06295		-2.9	-8.5	methanogenesis marker 14 protein
MMP_RS01925		-2.9	-8.1	DUF1616 domain-containing protein
MMP_RS01500		-2.9	-3.5	CBS domain-containing protein
MMP_RS05265		-2.9	-4.2	2-isopropylmalate synthase
MMP_RS01020		-2.9	-2.4	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS00750		-2.9	-3.7	fumarate hydratase
MMP_RS01220		-2.9	-11.1	hypothetical protein
MMP_RS02010		-2.8	-12.9	PHP domain-containing protein
MMP_RS05515		-2.8	-11.2	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS06685		-2.8	-16.1	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS01910		-2.8	-9.6	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
MMP_RS00305		-2.8	-3.6	phosphoribosyl-ATP diphosphatase
MMP_RS01900		-2.7	-13.2	hypothetical protein
MMP_RS03640		-2.7	-5.1	archaeal proteasome endopeptidase complex subunit beta
MMP_RS03315		-2.7	-2.1	ferrous iron transport protein A
MMP_RS02345		-2.7	-7.0	GTP-dependent dephospho-CoA kinase family protein
MMP_RS00685		-2.7	-5.1	2-phospho-L-lactate guanylyltransferase
MMP_RS04780		-2.7	-3.2	ribonuclease P
MMP_RS08820		-2.7	-6.6	hypothetical protein
MMP_RS00295		-2.6	-4.8	gamma carbonic anhydrase family protein
MMP_RS06625		-2.6	-3.6	DNA primase
MMP_RS01725		-2.6	-5.1	class I SAM-dependent methyltransferase family protein
MMP_RS03015		-2.6	-10.7	GTP 3' 8-cyclase MoaA
MMP_RS01610		-2.6	-5.9	hypothetical protein
MMP_RS06840		-2.5	-2.0	DNA-directed RNA polymerase subunit N
MMP_RS06285		-2.5	-4.0	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS01905		-2.5	-11.3	glycosyltransferase
MMP_RS04775		-2.5	-4.8	adenosylhomocysteinase
MMP_RS05345		-2.5	-8.1	hypothetical protein
MMP_RS07545		-2.4	-1.7	HTH domain-containing protein
MMP_RS02145		-2.4	-7.3	winged helix-turn-helix transcriptional regulator
MMP_RS02800		-2.4	-8.1	nucleotidyltransferase domain-containing protein
MMP_RS08635		-2.4	-3.0	UbiA family prenyltransferase
MMP_RS02165		-2.3	-10.6	tRNA-dihydrouridine synthase
MMP_RS05875		-2.3	-6.0	hydroxyethylthiazole kinase
MMP_RS05545		-2.3	-10.1	pyridoxal phosphate-dependent aminotransferase
MMP_RS03025		-2.3	-7.7	molybdenum cofactor guanylyltransferase
MMP_RS06400		-2.3	-2.2	4Fe-4S binding protein
MMP_RS04955		-2.2	-4.9	DNA topoisomerase I
MMP_RS07730		-2.2	-2.8	pyruvate synthase subunit beta
MMP_RS01890		-2.2	-4.3	nucleotide sugar dehydrogenase
MMP_RS06120		-2.2	-3.9	UPF0147 family protein
MMP_RS08460		-2.2	-3.7	proteasome-activating nucleotidase
MMP_RS07445		-2.2	-5.9	helix-turn-helix domain-containing protein
MMP_RS06730		-2.2	-2.7	phosphopantothenate/pantothenate synthetase
MMP_RS06345		-2.2	-14.8	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS06535		-2.2	-8.8	2-oxoacid:acceptor oxidoreductase family protein
MMP_RS04685		-2.1	-5.1	DUF126 domain-containing protein
MMP_RS00300		-2.1	-1.6	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS02355		-2.1	-4.6	30S ribosomal protein S27ae
MMP_RS02245		-2.1	-6.5	hypothetical protein
MMP_RS01225		-2.1	-7.4	DUF5379 domain-containing protein
MMP_RS08745		-2.1	-7.6	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS03475		-2.1	-1.2	hypothetical protein
MMP_RS01800		-2.1	-6.8	TIGR00303 family protein
MMP_RS06270		-2.0	-6.5	TIGR00300 family protein
MMP_RS01875		-2.0	-8.4	N-acetyltransferase
MMP_RS00515		-2.0	-2.0	DUF655 domain-containing protein
MMP_RS06340		-2.0	-11.0	phosphoadenosine phosphosulfate reductase family protein
MMP_RS01830		-2.0	-3.0	tRNA-Val
MMP_RS07580		-2.0	-5.5	DUF356 domain-containing protein
MMP_RS06310		-2.0	-3.0	NAD(P)/FAD-dependent oxidoreductase
MMP_RS05555		-2.0	-2.7	DUF4040 domain-containing protein
MMP_RS03700		-2.0	-8.4	sodium:proton antiporter
MMP_RS06670		-2.0	-4.1	glucose-6-phosphate isomerase
MMP_RS00895		-2.0	-4.8	hypothetical protein
MMP_RS06545		-2.0	-5.5	ferredoxin family protein
MMP_RS06230		-2.0	-3.5	helix-turn-helix domain-containing protein
MMP_RS07735		-1.9	-1.5	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS06715		-1.9	-15.1	cache domain-containing protein
MMP_RS06200		-1.9	-12.4	M24 family metallopeptidase
MMP_RS03155		-1.9	-7.9	precorrin-6A reductase
MMP_RS03035		-1.9	-4.1	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS02340		-1.9	-3.4	DNA-directed RNA polymerase subunit E''
MMP_RS07605		-1.9	-3.5	diadenylate cyclase
MMP_RS03435		-1.9	-2.6	ketol-acid reductoisomerase
MMP_RS06720		-1.9	-12.2	response regulator transcription factor
MMP_RS01880		-1.9	-4.2	DegT/DnrJ/EryC1/StrS family aminotransferase
MMP_RS06895		-1.9	-2.9	selenocysteine-specific translation elongation factor
MMP_RS02135		-1.9	-6.1	DUF5612 domain-containing protein
MMP_RS06705		-1.8	-6.6	formate/nitrite transporter family protein
MMP_RS00320		-1.8	-3.1	class I SAM-dependent methyltransferase
MMP_RS04615		-1.8	-4.1	PDGLE domain-containing protein
MMP_RS07575		-1.8	-4.5	RNA ligase partner protein
MMP_RS07750		-1.8	-4.7	DUF357 domain-containing protein
MMP_RS01265		-1.8	-5.5	hypothetical protein
MMP_RS00810		-1.8	-8.2	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS05250		-1.8	-2.7	NFYB/HAP3 family transcription factor subunit
MMP_RS01795		-1.8	-2.9	methanogenesis marker 6 protein
MMP_RS06885		-1.8	-3.4	50S ribosome-binding GTPase
MMP_RS04605		-1.8	-8.0	cobalt ECF transporter T component CbiQ
MMP_RS08300		-1.7	-2.3	metal-sulfur cluster assembly factor
MMP_RS06020		-1.7	-6.2	archaeoflavoprotein AfpA
MMP_RS07200		-1.7	-5.1	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS01885		-1.7	-5.5	Gfo/Idh/MocA family oxidoreductase
MMP_RS05930		-1.7	-4.1	3-isopropylmalate dehydratase large subunit
MMP_RS07630		-1.7	-2.3	ATP-binding cassette domain-containing protein
MMP_RS06630		-1.7	-1.7	UPF0058 family protein
MMP_RS03445		-1.7	-1.9	methanogenesis marker 17 protein
MMP_RS01665		-1.7	-4.7	DUF2111 domain-containing protein
MMP_RS06925		-1.7	-2.9	ribonuclease VapC4
MMP_RS08095		-1.7	-8.0	dethiobiotin synthase
MMP_RS07555		-1.6	-1.2	monovalent cation/H+ antiporter subunit E
MMP_RS07380		-1.6	-2.3	transcription elongation factor Spt5
MMP_RS08445		-1.6	-6.6	DUF2099 family protein
MMP_RS07685		-1.6	-9.2	TIGR01212 family radical SAM protein
MMP_RS04890		-1.6	-1.4	adenylyltransferase/cytidyltransferase family protein
MMP_RS01960		-1.6	-0.9	hypothetical protein
MMP_RS03140		-1.6	-9.6	hypothetical protein
MMP_RS08105		-1.5	-8.6	6-carboxyhexanoate--CoA ligase
MMP_RS08100		-1.5	-10.7	8-amino-7-oxononanoate synthase
MMP_RS06130		-1.5	-3.8	peptidylprolyl isomerase
MMP_RS06105		-1.5	-8.2	hydrogenase maturation peptidase HycI
MMP_RS01955		-1.5	-2.4	hypothetical protein
MMP_RS08440		-1.5	-5.3	cell division protein SepF
MMP_RS03145		-1.5	-8.6	fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
MMP_RS07845		-1.5	-3.9	LL-diaminopimelate aminotransferase
MMP_RS07600		-1.5	-3.1	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS03205		-1.5	-2.3	peptidyl-tRNA hydrolase Pth2
MMP_RS04500		-1.5	-11.9	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS05640		-1.5	-5.0	UTP--glucose-1-phosphate uridylyltransferase GalU
MMP_RS07955		-1.5	-3.8	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS03580		-1.5	-4.1	signal recognition particle-docking protein FtsY
MMP_RS06370		-1.5	-5.3	biotin synthase BioB
MMP_RS05425		-1.4	-5.2	monovalent cation/H+ antiporter complex subunit F
MMP_RS08435		-1.4	-3.5	Era-like GTP-binding protein
MMP_RS00115		-1.4	-10.8	radical SAM protein
MMP_RS04620		-1.4	-9.5	cobalt transporter CbiM
MMP_RS05540		-1.4	-3.5	hypothetical protein
MMP_RS03400		-1.4	-3.1	archease
MMP_RS07075		-1.4	-3.1	phosphomannomutase/phosphoglucomutase
MMP_RS01895		-1.4	-9.7	flippase
MMP_RS04870		-1.4	-5.3	TIGR02253 family HAD-type hydrolase
MMP_RS03250		-1.4	-2.9	MJ1244 family protein
MMP_RS03305		-1.4	-8.5	winged helix-turn-helix domain-containing protein
MMP_RS08165		-1.4	-1.2	phosphoglycerate dehydrogenase
MMP_RS08320		-1.4	-7.6	molybdopterin molybdotransferase MoeA
MMP_RS06540		-1.4	-4.4	3-methyl-2-oxobutanoate dehydrogenase subunit VorB
MMP_RS01325		-1.3	-1.8	dihydroneopterin aldolase family protein
MMP_RS00130		-1.3	-2.0	nickel-responsive transcriptional regulator NikR
MMP_RS07525		-1.3	-7.3	4Fe-4S binding protein
MMP_RS06940		-1.3	-2.6	polyprenyl diphosphate synthase
MMP_RS01700		-1.3	-1.7	dihydroxy-acid dehydratase
MMP_RS05765		-1.3	-7.7	M42 family metallopeptidase
MMP_RS05845		-1.2	-2.6	tRNA-intron lyase
MMP_RS05245		-1.2	-8.8	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS00985		-1.2	-5.4	CDC48 family AAA ATPase
MMP_RS02190		-1.2	-4.3	sulfopyruvate decarboxylase subunit alpha
MMP_RS04710		-1.2	-2.3	hypothetical protein
MMP_RS03110		-1.2	-4.1	glycosyltransferase family 2 protein
MMP_RS07645		-1.2	-5.6	aldehyde dehydrogenase family protein
MMP_RS02230		-1.2	-8.5	sodium-dependent transporter
MMP_RS06315		-1.2	-1.2	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS08650		-1.2	-2.7	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS05815		-1.2	-2.0	NOL1/NOP2/sun family putative RNA methylase
MMP_RS06215		-1.2	-2.7	30S ribosomal protein S6e
MMP_RS06725		-1.2	-5.8	hypothetical protein
MMP_RS00060		-1.2	-1.2	3-dehydroquinate synthase II
MMP_RS01250		-1.2	-6.4	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS08330		-1.1	-7.2	NADH-quinone oxidoreductase subunit H
MMP_RS01365		-1.1	-2.1	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS07195		-1.1	-7.7	M20 family metallo-hydrolase
MMP_RS06865		-1.1	-1.6	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS07755		-1.1	-0.9	DUF555 domain-containing protein
MMP_RS00290		-1.1	-4.9	hypothetical protein
MMP_RS05925		-1.1	-3.6	small nuclear ribonucleoprotein
MMP_RS05440		-1.1	-5.8	winged helix-turn-helix transcriptional regulator
MMP_RS08645		-1.1	-5.7	UPF0179 family protein
MMP_RS03555		-1.1	-6.9	transcriptional regulator
MMP_RS05550		-1.1	-1.0	cation:proton antiporter

Specific Phenotypes

For 2 genes in this experiment