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Experiment set15S706 for
Methanococcus maripaludis S2
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200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS03340
+0.8
1.4
ABC transporter ATP-binding protein
compare
MMP
_RS07125
+0.6
2.4
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS07115
+0.6
3.3
MBL fold metallo-hydrolase
compare
MMP
_RS05975
+0.6
2.0
hypothetical protein
compare
MMP
_RS08580
+0.5
3.8
flagellin
compare
MMP
_RS03215
+0.5
4.2
MBL fold metallo-hydrolase
compare
MMP
_RS01655
+0.5
2.9
DsrE family protein
compare
MMP
_RS09025
+0.5
1.1
hypothetical protein
compare
MMP
_RS08750
+0.5
2.0
hypothetical protein
compare
MMP
_RS08400
+0.4
3.1
MJ0307 family thioredoxin
compare
MMP
_RS01650
+0.4
0.9
sulfurtransferase TusA family protein
compare
MMP
_RS07135
+0.4
3.5
coenzyme F420 hydrogenase subunit beta
compare
MMP
_RS08310
+0.4
1.7
TMEM165/GDT1 family protein
compare
MMP
_RS08775
+0.4
2.8
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS08845
+0.4
3.4
archaellum operon transcriptional activator EarA family protein
compare
MMP
_RS01570
+0.4
1.5
hypothetical protein
compare
MMP
_RS08280
+0.4
2.1
proteasome assembly chaperone family protein
compare
MMP
_RS08265
+0.4
2.5
rubrerythrin
compare
MMP
_RS07130
+0.4
2.9
coenzyme F420 hydrogenase subunit gamma
compare
MMP
_RS01430
+0.4
3.3
mechanosensitive ion channel family protein
compare
MMP
_RS05985
+0.4
1.4
hypothetical protein
compare
MMP
_RS07680
+0.4
1.9
DUF366 family protein
compare
MMP
_RS08470
+0.4
2.8
ATP-binding cassette domain-containing protein
compare
MMP
_RS07120
+0.4
2.9
coenzyme F420 hydrogenase subunit alpha
compare
MMP
_RS07805
+0.3
2.5
ABC transporter permease
compare
MMP
_RS07345
+0.3
2.1
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS08640
+0.3
2.7
TIM barrel protein
compare
MMP
_RS07155
+0.3
2.4
MFS transporter
compare
MMP
_RS08835
+0.3
2.5
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMP
_RS01155
+0.3
2.5
XRE family transcriptional regulator
compare
MMP
_RS01275
+0.3
2.0
class III signal peptide-containing protein
compare
MMP
_RS08080
+0.3
2.8
YchF/TatD family DNA exonuclease
compare
MMP
_RS01320
+0.3
2.1
hypothetical protein
compare
MMP
_RS06585
+0.3
1.0
DMT family protein
compare
MMP
_RS00240
+0.3
2.6
type II secretion system F family protein
compare
MMP
_RS03800
+0.3
1.6
hypothetical protein
compare
MMP
_RS06930
+0.3
2.4
MBL fold metallo-hydrolase
compare
MMP
_RS06555
+0.3
1.7
cupin domain-containing protein
compare
MMP
_RS05990
+0.3
1.9
DsrE family protein
compare
MMP
_RS08830
+0.3
2.3
GTP-binding protein
compare
MMP
_RS07840
+0.3
1.5
ribonuclease III
compare
MMP
_RS00570
+0.3
0.9
protein-L-isoaspartate O-methyltransferase
compare
MMP
_RS08855
+0.3
1.8
hypothetical protein
compare
MMP
_RS01280
+0.3
2.4
DUF515 domain-containing protein
compare
MMP
_RS09050
+0.3
1.7
CAP domain-containing protein
compare
MMP
_RS00250
+0.3
2.5
Flp pilus assembly complex ATPase component TadA
compare
MMP
_RS08160
+0.3
1.6
EamA family transporter
compare
MMP
_RS00245
+0.3
2.4
type II secretion system F family protein
compare
MMP
_RS08850
+0.3
2.5
hypothetical protein
compare
MMP
_RS07835
+0.3
1.3
TldD/PmbA family protein
compare
MMP
_RS05960
+0.3
2.3
CoB--CoM heterodisulfide reductase subunit B
compare
MMP
_RS02360
+0.3
1.9
hypothetical protein
compare
MMP
_RS08665
+0.3
2.4
hypothetical protein
compare
MMP
_RS07850
+0.3
1.3
prephenate dehydratase
compare
MMP
_RS07880
+0.3
1.9
AAA family ATPase
compare
MMP
_RS03740
+0.3
1.2
indolepyruvate oxidoreductase subunit beta
compare
MMP
_RS01290
+0.3
2.2
class III signal peptide-containing protein
compare
MMP
_RS00655
+0.3
1.5
hypothetical protein
compare
MMP
_RS02495
+0.3
1.4
hypothetical protein
compare
MMP
_RS01270
+0.3
2.3
prepilin peptidase
compare
MMP
_RS02770
+0.3
1.9
hypothetical protein
compare
MMP
_RS08615
+0.3
1.1
flagellar protein G
compare
MMP
_RS08555
+0.3
1.3
hypothetical protein
compare
MMP
_RS02725
+0.3
2.1
molybdate ABC transporter permease subunit
compare
MMP
_RS05580
+0.3
2.4
glycosyltransferase
compare
MMP
_RS08390
+0.3
1.9
DUF5400 domain-containing protein
compare
MMP
_RS07185
+0.3
2.1
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS06975
+0.3
0.7
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS05715
+0.2
1.7
hypothetical protein
compare
MMP
_RS06335
+0.2
1.7
HAD family hydrolase
compare
MMP
_RS08485
+0.2
2.1
tungstate ABC transporter substrate-binding protein WtpA
compare
MMP
_RS07330
+0.2
2.2
membrane protein
compare
MMP
_RS06430
+0.2
1.7
6-carboxytetrahydropterin synthase QueD
compare
MMP
_RS01110
+0.2
1.7
FmdE family protein
compare
MMP
_RS05980
+0.2
1.9
ferritin
compare
MMP
_RS08620
+0.2
1.5
flagellar accessory protein FlaH
compare
MMP
_RS06485
+0.2
0.5
zinc ribbon domain-containing protein
compare
MMP
_RS08610
+0.2
2.1
flagellar protein F
compare
MMP
_RS07900
+0.2
1.3
YeeE/YedE family protein
compare
MMP
_RS00520
+0.2
0.6
RNA polymerase Rpb4 family protein
compare
MMP
_RS06140
+0.2
1.1
radical SAM protein
compare
MMP
_RS08205
+0.2
2.0
stage II sporulation protein M
compare
MMP
_RS05995
+0.2
1.8
FprA family A-type flavoprotein
compare
MMP
_RS07910
+0.2
1.6
NAD(P)H-hydrate dehydratase
compare
MMP
_RS01295
+0.2
1.7
hypothetical protein
compare
MMP
_RS08770
+0.2
1.8
hypothetical protein
compare
MMP
_RS04740
+0.2
1.5
DUF473 domain-containing protein
compare
MMP
_RS08995
+0.2
0.6
hypothetical protein
compare
MMP
_RS02020
+0.2
1.3
gamma-glutamylcyclotransferase
compare
MMP
_RS08755
+0.2
2.0
sodium:solute symporter family protein
compare
MMP
_RS03765
+0.2
1.6
CopG family ribbon-helix-helix protein
compare
MMP
_RS08250
+0.2
1.7
pyruvate kinase
compare
MMP
_RS01255
+0.2
1.7
amino acid ABC transporter ATP-binding protein
compare
MMP
_RS00535
+0.2
1.2
TIGR00375 family protein
compare
MMP
_RS08325
+0.2
1.6
hypothetical protein
compare
MMP
_RS00865
+0.2
1.2
SLC13 family permease
compare
MMP
_RS08940
+0.2
0.6
MetS family NSS transporter small subunit
compare
MMP
_RS00390
+0.2
1.7
ammonium transporter
compare
MMP
_RS06910
+0.2
1.4
RlmF-related methyltransferase
compare
MMP
_RS00140
+0.2
1.4
DUF192 domain-containing protein
compare
MMP
_RS01310
+0.2
1.9
hypothetical protein
compare
MMP
_RS00400
+0.2
1.6
tributyrin esterase
compare
MMP
_RS04530
+0.2
1.6
ABC transporter permease
compare
MMP
_RS08245
+0.2
1.4
DUF4013 domain-containing protein
compare
MMP
_RS02425
+0.2
1.8
hypothetical protein
compare
MMP
_RS02915
+0.2
1.4
amino acid ABC transporter permease
compare
MMP
_RS08285
+0.2
1.6
serine/threonine protein kinase
compare
MMP
_RS07150
+0.2
1.1
MTH895/ArsE family thioredoxin-like protein
compare
MMP
_RS06300
+0.2
1.6
ABC transporter substrate-binding protein
compare
MMP
_RS07970
+0.2
1.2
hypothetical protein
compare
MMP
_RS01125
+0.2
1.5
thioredoxin family protein
compare
MMP
_RS06515
+0.2
0.9
UPF0489 family protein
compare
MMP
_RS08315
+0.2
0.9
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMP
_RS01085
+0.2
0.8
hypothetical protein
compare
MMP
_RS06465
+0.2
1.8
NERD domain-containing protein
compare
MMP
_RS06050
+0.2
1.5
ZIP family metal transporter
compare
MMP
_RS01790
+0.2
1.5
restriction endonuclease
compare
MMP
_RS08480
+0.2
1.5
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS04790
+0.2
1.3
4-hydroxy-tetrahydrodipicolinate reductase
compare
MMP
_RS01115
+0.2
1.6
molybdopterin molybdotransferase MoeA
compare
MMP
_RS07640
+0.2
1.3
mechanosensitive ion channel family protein
compare
MMP
_RS02465
+0.2
1.4
hypothetical protein
compare
MMP
_RS08675
+0.2
0.8
class III signal peptide-containing protein
compare
MMP
_RS01285
+0.2
1.5
hypothetical protein
compare
MMP
_RS07095
+0.2
1.0
PspC domain-containing protein
compare
MMP
_RS01145
+0.2
1.7
ABC transporter ATP-binding protein
compare
MMP
_RS08405
+0.2
1.5
MFS transporter
compare
MMP
_RS04610
+0.2
1.0
Dabb family protein
compare
MMP
_RS08625
+0.2
1.5
type II/IV secretion system ATPase subunit
compare
MMP
_RS08430
+0.2
1.3
HAD family hydrolase
compare
MMP
_RS06000
+0.2
1.2
divalent-cation tolerance protein CutA
compare
MMP
_RS07915
+0.2
1.1
DUF4870 domain-containing protein
compare
MMP
_RS03895
+0.2
1.0
hypothetical protein
compare
MMP
_RS02550
+0.2
1.3
helix-turn-helix transcriptional regulator
compare
MMP
_RS01195
+0.2
0.5
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS02590
+0.2
1.2
low molecular weight phosphatase family protein
compare
MMP
_RS06760
+0.2
0.8
hypothetical protein
compare
MMP
_RS06665
+0.2
1.4
glycogen/starch synthase
compare
MMP
_RS07550
+0.2
1.5
L-serine ammonia-lyase iron-sulfur-dependent subunit alpha
compare
MMP
_RS01630
+0.2
1.3
N-glycosylase/DNA lyase
compare
MMP
_RS05315
+0.2
0.5
hypothetical protein
compare
MMP
_RS03465
+0.2
0.4
adenine phosphoribosyltransferase
compare
MMP
_RS01435
+0.2
0.9
DMT family transporter
compare
MMP
_RS02215
+0.2
1.5
ECF transporter S component
compare
MMP
_RS03350
+0.2
0.9
winged helix-turn-helix domain-containing protein
compare
MMP
_RS08700
+0.2
1.1
hypothetical protein
compare
MMP
_RS07855
+0.2
1.4
class I SAM-dependent methyltransferase
compare
MMP
_RS02385
+0.2
1.3
ATP-binding protein
compare
MMP
_RS05675
+0.2
0.6
phosphate ABC transporter ATP-binding protein PstB
compare
MMP
_RS08630
+0.2
1.2
archaellar assembly protein FlaJ
compare
MMP
_RS01305
+0.2
1.5
hypothetical protein
compare
MMP
_RS00980
+0.2
1.3
hypothetical protein
compare
MMP
_RS02595
+0.2
0.4
putative zinc-binding protein
compare
MMP
_RS08130
+0.2
1.3
IGHMBP2 family helicase
compare
MMP
_RS08670
+0.2
1.2
metallophosphoesterase
compare
MMP
_RS06190
+0.2
1.1
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
compare
MMP
_RS06550
+0.2
1.2
AMP-binding protein
compare
MMP
_RS07890
+0.2
0.8
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS09060
+0.2
1.4
hypothetical protein
compare
MMP
_RS06440
+0.2
1.2
CBS domain-containing protein
compare
MMP
_RS01855
+0.2
1.1
2-hydroxyacyl-CoA dehydratase family protein
compare
MMP
_RS07100
+0.2
1.3
hypothetical protein
compare
MMP
_RS02315
+0.2
1.2
RimK family alpha-L-glutamate ligase
compare
MMP
_RS02565
+0.2
1.4
hypothetical protein
compare
MMP
_RS02380
+0.2
1.1
ATP-binding protein
compare
MMP
_RS07985
+0.2
1.3
nitroreductase family protein
compare
MMP
_RS06045
+0.2
1.2
DNA polymerase
compare
MMP
_RS01060
+0.2
1.4
calcium/sodium antiporter
compare
MMP
_RS03450
+0.2
0.6
glycine synthesis protein GlyXS
(from data)
compare
MMP
_RS06655
+0.1
1.2
glycoside hydrolase family 15 protein
compare
MMP
_RS03965
+0.1
0.6
hypothetical protein
compare
MMP
_RS06150
+0.1
1.3
hypothetical protein
compare
MMP
_RS07570
+0.1
1.1
nucleotidyltransferase family protein
compare
MMP
_RS08455
+0.1
0.7
multiprotein bridging factor aMBF1
compare
MMP
_RS00100
+0.1
1.2
tRNA pseudouridine(13) synthase TruD
compare
MMP
_RS05895
+0.1
1.3
metallophosphoesterase
compare
MMP
_RS05490
+0.1
1.0
IMPACT family protein
compare
MMP
_RS01620
+0.1
0.8
hypothetical protein
compare
MMP
_RS06870
+0.1
1.0
DedA family protein
compare
MMP
_RS08475
+0.1
0.8
ABC transporter permease
compare
MMP
_RS04165
+0.1
0.8
TetR/AcrR family transcriptional regulator
compare
MMP
_RS05355
+0.1
0.2
hypothetical protein
compare
MMP
_RS00185
+0.1
1.2
potassium channel protein
compare
MMP
_RS00990
+0.1
0.5
hypothetical protein
compare
MMP
_RS02810
+0.1
1.1
hypothetical protein
compare
MMP
_RS04440
+0.1
1.1
nitrogenase iron protein
compare
MMP
_RS04995
+0.1
1.0
hypothetical protein
compare
MMP
_RS00630
+0.1
1.2
ECF transporter S component
compare
MMP
_RS03760
+0.1
1.0
hypothetical protein
compare
MMP
_RS00565
+0.1
0.9
CBS domain-containing protein
compare
MMP
_RS03535
+0.1
0.6
helix-turn-helix transcriptional regulator
compare
MMP
_RS01315
+0.1
1.2
DUF2341 domain-containing protein
compare
MMP
_RS04520
+0.1
0.7
nucleoside deaminase
compare
MMP
_RS08415
+0.1
0.7
radical SAM protein
compare
MMP
_RS02680
+0.1
1.1
ABC transporter permease
compare
MMP
_RS07595
+0.1
1.0
hypothetical protein
compare
MMP
_RS08490
+0.1
1.1
hypothetical protein
compare
MMP
_RS01300
+0.1
1.1
hypothetical protein
compare
MMP
_RS00960
+0.1
1.0
iron export ABC transporter permease subunit FetB
compare
MMP
_RS00640
+0.1
0.9
ABC transporter substrate-binding protein
compare
Specific Phenotypes
For 2 genes in this experiment