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Experiment set15S705 for
Methanococcus maripaludis S2
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200 most important genes:
gene
name
fitness
t score
description
MMP
_RS00305
-6.6
-4.3
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS00300
-6.1
-1.8
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS06700
-4.8
-17.0
hypothetical protein
compare
MMP
_RS01175
-4.6
-11.7
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS08720
-4.0
-3.4
4Fe-4S binding protein
compare
MMP
_RS06120
-3.9
-3.5
UPF0147 family protein
compare
MMP
_RS06730
-3.8
-4.1
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS01985
-3.7
-11.9
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMP
_RS01755
-3.7
-3.0
DUF2097 domain-containing protein
compare
MMP
_RS02280
-3.6
-2.1
DUF211 domain-containing protein
compare
MMP
_RS07005
-3.5
-1.5
4Fe-4S binding protein
compare
MMP
_RS01915
-3.5
-14.8
DUF354 domain-containing protein
compare
MMP
_RS05920
-3.5
-1.5
50S ribosomal protein L37e
compare
MMP
_RS06355
-3.4
-5.2
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS01005
-3.3
-3.5
riboflavin synthase
compare
MMP
_RS02345
-3.3
-5.7
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS06680
-3.3
-20.9
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS01925
-3.2
-9.3
DUF1616 domain-containing protein
compare
MMP
_RS06350
-3.1
-8.5
HesA/MoeB/ThiF family protein
compare
MMP
_RS06685
-3.0
-21.3
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS04585
-3.0
-11.5
AIR synthase related protein
compare
MMP
_RS03315
-2.9
-2.2
ferrous iron transport protein A
compare
MMP
_RS02195
-2.9
-7.0
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS03025
-2.9
-7.7
molybdenum cofactor guanylyltransferase
compare
MMP
_RS07735
-2.8
-2.1
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS07635
-2.8
-12.5
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS06285
-2.8
-5.4
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS01220
-2.8
-9.6
hypothetical protein
compare
MMP
_RS07600
-2.8
-3.4
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS08635
-2.8
-4.1
UbiA family prenyltransferase
compare
MMP
_RS03015
-2.7
-16.8
GTP 3' 8-cyclase MoaA
compare
MMP
_RS03640
-2.7
-7.0
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS05515
-2.7
-12.2
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS06475
-2.7
-6.7
FAD-dependent oxidoreductase
compare
MMP
_RS01910
-2.7
-9.2
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMP
_RS07380
-2.7
-3.4
transcription elongation factor Spt5
compare
MMP
_RS04775
-2.6
-5.3
adenosylhomocysteinase
compare
MMP
_RS01920
-2.6
-12.3
glycosyltransferase family 2 protein
compare
MMP
_RS01385
-2.6
-1.5
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS08300
-2.6
-2.3
metal-sulfur cluster assembly factor
compare
MMP
_RS02010
-2.5
-15.6
PHP domain-containing protein
compare
MMP
_RS07435
-2.5
-4.5
GMP synthase subunit A
compare
MMP
_RS01970
-2.5
-8.3
TIGR04279 domain-containing protein
compare
MMP
_RS06295
-2.5
-8.5
methanogenesis marker 14 protein
compare
MMP
_RS02165
-2.4
-10.3
tRNA-dihydrouridine synthase
compare
MMP
_RS02800
-2.4
-7.8
nucleotidyltransferase domain-containing protein
compare
MMP
_RS03400
-2.4
-4.3
archease
compare
MMP
_RS01955
-2.4
-3.0
hypothetical protein
compare
MMP
_RS05345
-2.4
-8.5
hypothetical protein
compare
MMP
_RS08715
-2.3
-2.7
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS03035
-2.3
-5.0
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS00685
-2.3
-6.4
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS06715
-2.3
-17.2
cache domain-containing protein
compare
MMP
_RS01800
-2.3
-4.9
TIGR00303 family protein
compare
MMP
_RS06720
-2.3
-10.7
response regulator transcription factor
compare
MMP
_RS06345
-2.3
-15.8
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS04710
-2.3
-3.7
hypothetical protein
compare
MMP
_RS00110
-2.2
-5.2
hypothetical protein
compare
MMP
_RS07605
-2.2
-6.4
diadenylate cyclase
compare
MMP
_RS05250
-2.2
-2.7
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS01900
-2.2
-11.9
hypothetical protein
compare
MMP
_RS06020
-2.2
-5.7
archaeoflavoprotein AfpA
compare
MMP
_RS08210
-2.2
-4.6
phosphatidylglycerophosphatase A
compare
MMP
_RS01725
-2.2
-7.0
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS05845
-2.1
-3.1
tRNA-intron lyase
compare
MMP
_RS01225
-2.1
-8.8
DUF5379 domain-containing protein
compare
MMP
_RS00895
-2.1
-6.1
hypothetical protein
compare
MMP
_RS00695
-2.1
-2.2
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS09020
-2.1
-2.4
hypothetical protein
compare
MMP
_RS01905
-2.1
-10.5
glycosyltransferase
compare
MMP
_RS02240
-2.1
-5.3
methanogenesis marker 7 protein
compare
MMP
_RS04890
-2.1
-1.9
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS03155
-2.1
-8.5
precorrin-6A reductase
compare
MMP
_RS07445
-2.1
-6.5
helix-turn-helix domain-containing protein
compare
MMP
_RS05875
-2.1
-7.2
hydroxyethylthiazole kinase
compare
MMP
_RS03960
-2.1
-1.9
hypothetical protein
compare
MMP
_RS06885
-2.1
-3.9
50S ribosome-binding GTPase
compare
MMP
_RS02355
-2.0
-6.5
30S ribosomal protein S27ae
compare
MMP
_RS06270
-2.0
-7.7
TIGR00300 family protein
compare
MMP
_RS06625
-2.0
-3.1
DNA primase
compare
MMP
_RS01020
-2.0
-2.4
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS08790
-2.0
-4.8
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS06400
-2.0
-3.6
4Fe-4S binding protein
compare
MMP
_RS08820
-2.0
-8.4
hypothetical protein
compare
MMP
_RS06200
-2.0
-12.5
M24 family metallopeptidase
compare
MMP
_RS05545
-2.0
-10.1
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS01500
-2.0
-3.7
CBS domain-containing protein
compare
MMP
_RS07730
-2.0
-3.5
pyruvate synthase subunit beta
compare
MMP
_RS08745
-2.0
-8.1
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS00320
-2.0
-3.9
class I SAM-dependent methyltransferase
compare
MMP
_RS01830
-1.9
-2.9
tRNA-Val
compare
MMP
_RS01610
-1.9
-4.1
hypothetical protein
compare
MMP
_RS04780
-1.9
-3.4
ribonuclease P
compare
MMP
_RS02900
-1.9
-1.1
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS03445
-1.9
-2.1
methanogenesis marker 17 protein
compare
MMP
_RS06895
-1.9
-3.4
selenocysteine-specific translation elongation factor
compare
MMP
_RS06925
-1.9
-4.4
ribonuclease VapC4
compare
MMP
_RS01265
-1.8
-3.7
hypothetical protein
compare
MMP
_RS06705
-1.8
-6.4
formate/nitrite transporter family protein
compare
MMP
_RS05265
-1.8
-3.1
2-isopropylmalate synthase
compare
MMP
_RS05815
-1.8
-1.6
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS06130
-1.8
-3.8
peptidylprolyl isomerase
compare
MMP
_RS07545
-1.8
-1.7
HTH domain-containing protein
compare
MMP
_RS06340
-1.7
-8.8
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS02135
-1.7
-4.7
DUF5612 domain-containing protein
compare
MMP
_RS04685
-1.7
-4.2
DUF126 domain-containing protein
compare
MMP
_RS04720
-1.7
-2.7
DedA family protein
compare
MMP
_RS07755
-1.7
-2.5
DUF555 domain-containing protein
compare
MMP
_RS01960
-1.7
-1.0
hypothetical protein
compare
MMP
_RS02245
-1.7
-6.8
hypothetical protein
compare
MMP
_RS02340
-1.7
-4.8
DNA-directed RNA polymerase subunit E''
compare
MMP
_RS00810
-1.7
-8.8
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMP
_RS02190
-1.7
-3.4
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS00295
-1.7
-4.8
gamma carbonic anhydrase family protein
compare
MMP
_RS01795
-1.7
-3.0
methanogenesis marker 6 protein
compare
MMP
_RS07580
-1.6
-3.4
DUF356 domain-containing protein
compare
MMP
_RS06535
-1.6
-7.1
2-oxoacid:acceptor oxidoreductase family protein
compare
MMP
_RS06940
-1.6
-3.3
polyprenyl diphosphate synthase
compare
MMP
_RS06315
-1.6
-1.6
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS06545
-1.6
-6.8
ferredoxin family protein
compare
MMP
_RS06105
-1.6
-8.0
hydrogenase maturation peptidase HycI
compare
MMP
_RS08460
-1.6
-3.8
proteasome-activating nucleotidase
compare
MMP
_RS05550
-1.6
-1.4
cation:proton antiporter
compare
MMP
_RS03205
-1.6
-2.7
peptidyl-tRNA hydrolase Pth2
compare
MMP
_RS04955
-1.6
-4.7
DNA topoisomerase I
compare
MMP
_RS07845
-1.6
-2.7
LL-diaminopimelate aminotransferase
compare
MMP
_RS08435
-1.5
-3.7
Era-like GTP-binding protein
compare
MMP
_RS03700
-1.5
-6.9
sodium:proton antiporter
compare
MMP
_RS06840
-1.5
-1.7
DNA-directed RNA polymerase subunit N
compare
MMP
_RS06670
-1.5
-2.8
glucose-6-phosphate isomerase
compare
MMP
_RS03435
-1.5
-2.1
ketol-acid reductoisomerase
compare
MMP
_RS05540
-1.5
-3.3
hypothetical protein
compare
MMP
_RS07750
-1.5
-5.6
DUF357 domain-containing protein
compare
MMP
_RS01325
-1.5
-2.9
dihydroneopterin aldolase family protein
compare
MMP
_RS03250
-1.5
-3.5
MJ1244 family protein
compare
MMP
_RS07200
-1.5
-6.1
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS01700
-1.5
-1.9
dihydroxy-acid dehydratase
compare
MMP
_RS00750
-1.5
-3.0
fumarate hydratase
compare
MMP
_RS07575
-1.5
-4.0
RNA ligase partner protein
compare
MMP
_RS06230
-1.5
-3.5
helix-turn-helix domain-containing protein
compare
MMP
_RS06310
-1.5
-2.3
NAD(P)/FAD-dependent oxidoreductase
compare
MMP
_RS07525
-1.4
-7.2
4Fe-4S binding protein
compare
MMP
_RS01665
-1.4
-4.9
DUF2111 domain-containing protein
compare
MMP
_RS06540
-1.4
-4.8
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMP
_RS03555
-1.4
-8.5
transcriptional regulator
compare
MMP
_RS05925
-1.4
-5.8
small nuclear ribonucleoprotein
compare
MMP
_RS01875
-1.4
-6.5
N-acetyltransferase
compare
MMP
_RS00515
-1.4
-1.8
DUF655 domain-containing protein
compare
MMP
_RS03475
-1.4
-1.1
hypothetical protein
compare
MMP
_RS04870
-1.4
-5.5
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS08320
-1.4
-6.2
molybdopterin molybdotransferase MoeA
compare
MMP
_RS03305
-1.4
-9.1
winged helix-turn-helix domain-containing protein
compare
MMP
_RS08105
-1.3
-9.0
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS00985
-1.3
-5.5
CDC48 family AAA ATPase
compare
MMP
_RS08445
-1.3
-5.8
DUF2099 family protein
compare
MMP
_RS03140
-1.3
-9.9
hypothetical protein
compare
MMP
_RS00520
-1.3
-2.3
RNA polymerase Rpb4 family protein
compare
MMP
_RS07075
-1.3
-2.8
phosphomannomutase/phosphoglucomutase
compare
MMP
_RS01885
-1.3
-4.6
Gfo/Idh/MocA family oxidoreductase
compare
MMP
_RS03600
-1.3
-3.3
triose-phosphate isomerase
compare
MMP
_RS05425
-1.3
-5.0
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS07190
-1.3
-7.7
chromosome segregation protein SMC
compare
MMP
_RS04605
-1.3
-4.7
cobalt ECF transporter T component CbiQ
compare
MMP
_RS08645
-1.3
-7.4
UPF0179 family protein
compare
MMP
_RS05640
-1.3
-5.5
UTP--glucose-1-phosphate uridylyltransferase GalU
compare
MMP
_RS00115
-1.3
-10.0
radical SAM protein
compare
MMP
_RS01880
-1.3
-4.7
DegT/DnrJ/EryC1/StrS family aminotransferase
compare
MMP
_RS08440
-1.2
-3.9
cell division protein SepF
compare
MMP
_RS04615
-1.2
-3.5
PDGLE domain-containing protein
compare
MMP
_RS06370
-1.2
-4.8
biotin synthase BioB
compare
MMP
_RS06630
-1.2
-1.5
UPF0058 family protein
compare
MMP
_RS07685
-1.2
-7.6
TIGR01212 family radical SAM protein
compare
MMP
_RS02145
-1.2
-4.2
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS08095
-1.2
-7.4
dethiobiotin synthase
compare
MMP
_RS04500
-1.2
-9.4
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS01545
-1.2
-1.9
CBS domain-containing protein
compare
MMP
_RS05765
-1.2
-6.9
M42 family metallopeptidase
compare
MMP
_RS06725
-1.2
-7.2
hypothetical protein
compare
MMP
_RS05930
-1.2
-2.4
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS05555
-1.2
-1.9
DUF4040 domain-containing protein
compare
MMP
_RS08100
-1.2
-7.8
8-amino-7-oxononanoate synthase
compare
MMP
_RS03145
-1.1
-6.9
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS03095
-1.1
-5.7
diphthine synthase
compare
MMP
_RS00290
-1.1
-4.1
hypothetical protein
compare
MMP
_RS08330
-1.1
-4.6
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS04875
-1.1
-4.1
energy-converting hydrogenase B subunit P
compare
MMP
_RS02230
-1.1
-8.0
sodium-dependent transporter
compare
MMP
_RS02885
-1.1
-9.0
molybdopterin biosynthesis protein
compare
MMP
_RS01365
-1.0
-1.8
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS07630
-1.0
-1.8
ATP-binding cassette domain-containing protein
compare
MMP
_RS01890
-1.0
-2.9
nucleotide sugar dehydrogenase
compare
MMP
_RS02875
-1.0
-6.7
chorismate pyruvate-lyase family protein
compare
MMP
_RS02170
-1.0
-6.0
CBS domain-containing protein
compare
MMP
_RS05245
-1.0
-6.9
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMP
_RS01895
-1.0
-6.7
flippase
compare
MMP
_RS07790
-1.0
-6.7
segregation/condensation protein A
compare
MMP
_RS08335
-0.9
-5.9
NADH-quinone oxidoreductase subunit B family protein
compare
MMP
_RS04015
-0.9
-1.5
hypothetical protein
compare
MMP
_RS00900
-0.9
-2.4
50S ribosomal protein L39e
compare
MMP
_RS07955
-0.9
-4.2
FumA C-terminus/TtdB family hydratase beta subunit
compare
Specific Phenotypes
For 2 genes in this experiment