Experiment set15S704 for Methanococcus maripaludis S2

Compare to:

Formate 100 mM hypophosphite

200 most important genes:

  gene name fitness t score description  
MMP_RS06400 -7.2 -3.5 4Fe-4S binding protein compare
MMP_RS07075 -5.5 -3.8 phosphomannomutase/phosphoglucomutase compare
MMP_RS08210 -5.2 -3.4 phosphatidylglycerophosphatase A compare
MMP_RS01955 -5.1 -3.1 hypothetical protein compare
MMP_RS06670 -5.0 -3.4 glucose-6-phosphate isomerase compare
MMP_RS01915 -4.9 -8.9 DUF354 domain-containing protein compare
MMP_RS07555 -4.9 -1.4 monovalent cation/H+ antiporter subunit E compare
MMP_RS01970 -4.7 -13.9 TIGR04279 domain-containing protein compare
MMP_RS01910 -4.7 -7.2 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS05920 -4.6 -1.3 50S ribosomal protein L37e compare
MMP_RS01920 -4.6 -18.0 glycosyltransferase family 2 protein compare
MMP_RS01890 -4.5 -4.4 nucleotide sugar dehydrogenase compare
MMP_RS01875 -4.5 -9.6 N-acetyltransferase compare
MMP_RS08720 -4.4 -2.7 4Fe-4S binding protein compare
MMP_RS01880 -4.3 -6.9 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01895 -4.3 -15.9 flippase compare
MMP_RS06630 -4.2 -1.7 UPF0058 family protein compare
MMP_RS03315 -4.2 -2.0 ferrous iron transport protein A compare
MMP_RS01500 -4.2 -3.7 CBS domain-containing protein compare
MMP_RS05555 -4.1 -2.2 DUF4040 domain-containing protein compare
MMP_RS09020 -4.0 -2.0 hypothetical protein compare
MMP_RS02355 -4.0 -4.9 30S ribosomal protein S27ae compare
MMP_RS01545 -3.9 -1.9 CBS domain-containing protein compare
MMP_RS08790 -3.9 -3.1 translation initiation factor IF-2 subunit alpha compare
MMP_RS00685 -3.7 -4.2 2-phospho-L-lactate guanylyltransferase compare
MMP_RS05640 -3.7 -6.7 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS01885 -3.6 -7.0 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS00305 -3.6 -2.9 phosphoribosyl-ATP diphosphatase compare
MMP_RS04720 -3.6 -3.9 DedA family protein compare
MMP_RS00130 -3.6 -2.0 nickel-responsive transcriptional regulator NikR compare
MMP_RS08785 -3.5 -1.7 RNA-protein complex protein Nop10 compare
MMP_RS01940 -3.5 -4.9 MoxR family ATPase compare
MMP_RS01905 -3.5 -10.8 glycosyltransferase compare
MMP_RS01175 -3.5 -5.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03700 -3.5 -11.1 sodium:proton antiporter compare
MMP_RS05515 -3.5 -8.5 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS01925 -3.4 -7.3 DUF1616 domain-containing protein compare
MMP_RS02145 -3.4 -5.7 winged helix-turn-helix transcriptional regulator compare
MMP_RS06355 -3.4 -4.2 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS07635 -3.4 -8.2 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06700 -3.4 -15.1 hypothetical protein compare
MMP_RS03025 -3.4 -7.4 molybdenum cofactor guanylyltransferase compare
MMP_RS01985 -3.3 -7.6 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS06350 -3.3 -5.9 HesA/MoeB/ThiF family protein compare
MMP_RS02165 -3.3 -10.5 tRNA-dihydrouridine synthase compare
MMP_RS01020 -3.2 -1.8 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS02345 -3.2 -4.7 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS08715 -3.1 -2.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS03015 -3.1 -12.2 GTP 3' 8-cyclase MoaA compare
MMP_RS06120 -3.1 -3.1 UPF0147 family protein compare
MMP_RS06345 -3.1 -12.5 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06230 -3.1 -4.0 helix-turn-helix domain-containing protein compare
MMP_RS06680 -3.0 -16.1 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS04585 -3.0 -9.7 AIR synthase related protein compare
MMP_RS05545 -3.0 -6.3 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS00750 -3.0 -4.4 fumarate hydratase compare
MMP_RS01900 -3.0 -16.4 hypothetical protein compare
MMP_RS07685 -3.0 -9.9 TIGR01212 family radical SAM protein compare
MMP_RS08370 -2.9 -1.2 cation:proton antiporter subunit C compare
MMP_RS07575 -2.9 -6.7 RNA ligase partner protein compare
MMP_RS03600 -2.9 -3.3 triose-phosphate isomerase compare
MMP_RS01975 -2.9 -11.5 hypothetical protein compare
MMP_RS03580 -2.9 -4.6 signal recognition particle-docking protein FtsY compare
MMP_RS00695 -2.8 -1.5 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06685 -2.8 -15.5 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08300 -2.8 -1.6 metal-sulfur cluster assembly factor compare
MMP_RS00120 -2.8 -4.4 LysR family transcriptional regulator compare
MMP_RS02280 -2.7 -1.5 DUF211 domain-containing protein compare
MMP_RS08070 -2.7 -11.0 DUF2096 domain-containing protein compare
MMP_RS05250 -2.7 -2.3 NFYB/HAP3 family transcription factor subunit compare
MMP_RS01725 -2.7 -4.7 class I SAM-dependent methyltransferase family protein compare
MMP_RS05765 -2.7 -8.8 M42 family metallopeptidase compare
MMP_RS00985 -2.7 -6.7 CDC48 family AAA ATPase compare
MMP_RS05430 -2.7 -4.8 TIGR00288 family NYN domain-containing protein compare
MMP_RS03305 -2.7 -12.5 winged helix-turn-helix domain-containing protein compare
MMP_RS07005 -2.7 -1.1 4Fe-4S binding protein compare
MMP_RS06285 -2.7 -3.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07730 -2.7 -2.5 pyruvate synthase subunit beta compare
MMP_RS01830 -2.6 -2.2 tRNA-Val compare
MMP_RS01945 -2.6 -7.0 DUF4350 domain-containing protein compare
MMP_RS08075 -2.6 -7.2 DUF749 domain-containing protein compare
MMP_RS05550 -2.6 -1.3 cation:proton antiporter compare
MMP_RS00235 -2.6 -10.6 HDIG domain-containing protein conserved
MMP_RS07445 -2.6 -6.2 helix-turn-helix domain-containing protein compare
MMP_RS06940 -2.6 -3.3 polyprenyl diphosphate synthase compare
MMP_RS00335 -2.6 -6.3 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS06855 -2.6 -14.2 hypothetical protein compare
MMP_RS00300 -2.6 -1.2 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS05425 -2.6 -6.9 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS01380 -2.6 -3.5 PHP domain-containing protein compare
MMP_RS07605 -2.5 -4.1 diadenylate cyclase compare
MMP_RS08745 -2.5 -6.8 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06370 -2.5 -7.9 biotin synthase BioB compare
MMP_RS02340 -2.5 -3.9 DNA-directed RNA polymerase subunit E'' compare
MMP_RS01335 -2.5 -3.3 prefoldin subunit beta compare
MMP_RS03095 -2.5 -9.5 diphthine synthase compare
MMP_RS08320 -2.5 -8.1 molybdopterin molybdotransferase MoeA compare
MMP_RS02800 -2.5 -6.4 nucleotidyltransferase domain-containing protein compare
MMP_RS06200 -2.5 -11.3 M24 family metallopeptidase compare
MMP_RS04780 -2.5 -3.7 ribonuclease P compare
MMP_RS06310 -2.5 -3.1 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS05925 -2.5 -4.4 small nuclear ribonucleoprotein compare
MMP_RS02240 -2.5 -4.4 methanogenesis marker 7 protein compare
MMP_RS04710 -2.5 -2.6 hypothetical protein compare
MMP_RS06295 -2.5 -7.0 methanogenesis marker 14 protein compare
MMP_RS07380 -2.4 -2.5 transcription elongation factor Spt5 compare
MMP_RS03685 -2.4 -14.9 Mrp/NBP35 family ATP-binding protein compare
MMP_RS02235 -2.4 -11.4 CBS domain-containing protein compare
MMP_RS00810 -2.4 -10.4 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS03140 -2.4 -14.5 hypothetical protein compare
MMP_RS06885 -2.4 -3.3 50S ribosome-binding GTPase compare
MMP_RS05875 -2.4 -6.1 hydroxyethylthiazole kinase compare
MMP_RS06715 -2.4 -16.3 cache domain-containing protein compare
MMP_RS06730 -2.4 -3.1 phosphopantothenate/pantothenate synthetase compare
MMP_RS01935 -2.4 -7.9 DUF58 domain-containing protein compare
MMP_RS03205 -2.4 -2.3 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS02195 -2.4 -4.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS00295 -2.4 -3.7 gamma carbonic anhydrase family protein compare
MMP_RS01220 -2.3 -10.3 hypothetical protein compare
MMP_RS01180 -2.3 -2.3 XTP/dITP diphosphatase compare
MMP_RS03155 -2.3 -8.4 precorrin-6A reductase compare
MMP_RS08690 -2.3 -8.7 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS02875 -2.3 -11.0 chorismate pyruvate-lyase family protein compare
MMP_RS04615 -2.3 -6.7 PDGLE domain-containing protein compare
MMP_RS04870 -2.3 -5.7 TIGR02253 family HAD-type hydrolase compare
MMP_RS02885 -2.3 -14.2 molybdopterin biosynthesis protein compare
MMP_RS08645 -2.3 -7.5 UPF0179 family protein compare
MMP_RS01225 -2.3 -6.0 DUF5379 domain-containing protein compare
MMP_RS01800 -2.3 -4.4 TIGR00303 family protein compare
MMP_RS00310 -2.3 -8.9 CBS domain-containing protein compare
MMP_RS06980 -2.3 -8.7 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS02170 -2.3 -5.4 CBS domain-containing protein compare
MMP_RS06105 -2.2 -9.4 hydrogenase maturation peptidase HycI compare
MMP_RS04685 -2.2 -4.5 DUF126 domain-containing protein compare
MMP_RS03145 -2.2 -9.7 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS08000 -2.2 -14.7 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS04605 -2.2 -7.0 cobalt ECF transporter T component CbiQ compare
MMP_RS02870 -2.1 -10.1 hypothetical protein compare
MMP_RS01610 -2.1 -2.3 hypothetical protein compare
MMP_RS07750 -2.1 -5.4 DUF357 domain-containing protein compare
MMP_RS03960 -2.1 -1.4 hypothetical protein compare
MMP_RS01045 -2.1 -7.3 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS01930 -2.1 -10.6 hypothetical protein compare
MMP_RS06720 -2.1 -11.7 response regulator transcription factor compare
MMP_RS07390 -2.1 -2.2 cell division protein FtsZ compare
MMP_RS01005 -2.1 -2.3 riboflavin synthase compare
MMP_RS04775 -2.1 -4.1 adenosylhomocysteinase compare
MMP_RS06315 -2.1 -1.2 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS01950 -2.1 -6.7 hypothetical protein compare
MMP_RS08820 -2.1 -4.3 hypothetical protein compare
MMP_RS05245 -2.0 -11.4 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS01840 -2.0 -7.5 TIGR00289 family protein compare
MMP_RS03475 -2.0 -1.0 hypothetical protein compare
MMP_RS06175 -2.0 -7.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS04875 -2.0 -7.0 energy-converting hydrogenase B subunit P compare
MMP_RS01960 -2.0 -0.8 hypothetical protein compare
MMP_RS01330 -2.0 -12.2 DHH family phosphoesterase compare
MMP_RS07735 -2.0 -1.3 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS05445 -2.0 -8.8 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS07365 -2.0 -10.7 2-phosphoglycerate kinase compare
MMP_RS07580 -2.0 -4.6 DUF356 domain-containing protein compare
MMP_RS07755 -2.0 -1.8 DUF555 domain-containing protein compare
MMP_RS05440 -1.9 -8.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS06860 -1.9 -2.4 4Fe-4S binding protein compare
MMP_RS03035 -1.9 -5.4 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS04620 -1.9 -9.9 cobalt transporter CbiM compare
MMP_RS01325 -1.9 -3.1 dihydroneopterin aldolase family protein compare
MMP_RS01795 -1.9 -1.5 methanogenesis marker 6 protein compare
MMP_RS08650 -1.9 -3.5 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS03445 -1.9 -1.6 methanogenesis marker 17 protein compare
MMP_RS04890 -1.9 -1.3 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS03640 -1.8 -4.4 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS08840 -1.8 -10.5 class I SAM-dependent methyltransferase compare
MMP_RS06270 -1.8 -5.6 TIGR00300 family protein compare
MMP_RS02245 -1.8 -4.1 hypothetical protein compare
MMP_RS04500 -1.8 -11.4 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS00115 -1.8 -10.8 radical SAM protein compare
MMP_RS00895 -1.8 -3.6 hypothetical protein compare
MMP_RS01665 -1.8 -4.0 DUF2111 domain-containing protein compare
MMP_RS01265 -1.8 -2.1 hypothetical protein compare
MMP_RS06895 -1.8 -2.5 selenocysteine-specific translation elongation factor compare
MMP_RS03250 -1.8 -2.4 MJ1244 family protein compare
MMP_RS00345 -1.8 -7.9 DUF2666 domain-containing protein compare
MMP_RS05110 -1.8 -8.0 16S ribosomal RNA methyltransferase A compare
MMP_RS00110 -1.8 -3.3 hypothetical protein compare
MMP_RS05450 -1.8 -5.2 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS04480 -1.8 -13.7 lysine 2 3-aminomutase compare
MMP_RS03400 -1.7 -3.4 archease compare
MMP_RS04485 -1.7 -10.2 putative beta-lysine N-acetyltransferase compare
MMP_RS03390 -1.7 -6.7 malate dehydrogenase compare
MMP_RS07630 -1.7 -1.7 ATP-binding cassette domain-containing protein compare
MMP_RS07600 -1.7 -3.1 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS01755 -1.7 -1.7 DUF2097 domain-containing protein compare
MMP_RS01385 -1.7 -0.9 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS05540 -1.7 -2.7 hypothetical protein compare
MMP_RS08095 -1.6 -6.5 dethiobiotin synthase compare
MMP_RS00060 -1.6 -2.3 3-dehydroquinate synthase II compare
MMP_RS00720 -1.6 -9.9 metal-dependent hydrolase compare
MMP_RS07435 -1.6 -1.7 GMP synthase subunit A compare
MMP_RS06925 -1.6 -2.8 ribonuclease VapC4 compare


Specific Phenotypes

For 7 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis S2

For stress Sodium hypophosphite across organisms