Experiment set15S703 for Methanococcus maripaludis S2

Compare to:

Formate 100 mM hypophosphite

200 most important genes:

  gene name fitness t score description  
MMP_RS08715 -5.8 -2.3 formylmethanofuran dehydrogenase subunit B compare
MMP_RS02355 -5.6 -3.2 30S ribosomal protein S27ae compare
MMP_RS07075 -5.2 -2.9 phosphomannomutase/phosphoglucomutase compare
MMP_RS02345 -5.2 -3.9 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS03600 -4.9 -2.9 triose-phosphate isomerase compare
MMP_RS01970 -4.8 -12.1 TIGR04279 domain-containing protein compare
MMP_RS01800 -4.8 -5.1 TIGR00303 family protein compare
MMP_RS07555 -4.6 -0.9 monovalent cation/H+ antiporter subunit E compare
MMP_RS05920 -4.5 -0.9 50S ribosomal protein L37e compare
MMP_RS03025 -4.4 -6.2 molybdenum cofactor guanylyltransferase compare
MMP_RS07005 -4.4 -0.9 4Fe-4S binding protein compare
MMP_RS08210 -4.3 -2.4 phosphatidylglycerophosphatase A compare
MMP_RS02340 -4.1 -3.0 DNA-directed RNA polymerase subunit E'' compare
MMP_RS01880 -4.1 -8.2 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS08785 -4.1 -1.1 RNA-protein complex protein Nop10 compare
MMP_RS01920 -4.1 -15.7 glycosyltransferase family 2 protein compare
MMP_RS00685 -4.0 -4.6 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01915 -4.0 -11.2 DUF354 domain-containing protein compare
MMP_RS06315 -3.9 -1.1 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS04890 -3.9 -1.1 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS03315 -3.9 -1.3 ferrous iron transport protein A compare
MMP_RS04710 -3.7 -1.8 hypothetical protein compare
MMP_RS01875 -3.6 -8.5 N-acetyltransferase compare
MMP_RS06350 -3.5 -7.4 HesA/MoeB/ThiF family protein compare
MMP_RS01910 -3.5 -8.5 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS01885 -3.5 -7.0 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS05515 -3.4 -7.7 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS08745 -3.4 -7.4 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS02245 -3.4 -4.2 hypothetical protein compare
MMP_RS06285 -3.4 -2.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS01225 -3.3 -6.3 DUF5379 domain-containing protein compare
MMP_RS04685 -3.3 -3.1 DUF126 domain-containing protein compare
MMP_RS06400 -3.3 -1.8 4Fe-4S binding protein compare
MMP_RS02240 -3.3 -2.3 methanogenesis marker 7 protein compare
MMP_RS01955 -3.3 -2.3 hypothetical protein compare
MMP_RS01890 -3.2 -4.2 nucleotide sugar dehydrogenase compare
MMP_RS01175 -3.2 -5.8 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS01020 -3.2 -1.2 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS05640 -3.2 -5.7 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS00295 -3.1 -2.7 gamma carbonic anhydrase family protein compare
MMP_RS01895 -3.1 -11.3 flippase compare
MMP_RS08720 -3.1 -1.8 4Fe-4S binding protein compare
MMP_RS03015 -3.1 -12.1 GTP 3' 8-cyclase MoaA compare
MMP_RS01220 -3.1 -7.8 hypothetical protein compare
MMP_RS01610 -3.1 -3.1 hypothetical protein compare
MMP_RS06630 -3.0 -1.2 UPF0058 family protein compare
MMP_RS02165 -3.0 -10.7 tRNA-dihydrouridine synthase compare
MMP_RS05875 -3.0 -6.6 hydroxyethylthiazole kinase compare
MMP_RS06680 -3.0 -15.3 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS08300 -3.0 -1.4 metal-sulfur cluster assembly factor compare
MMP_RS01985 -3.0 -6.3 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS03700 -3.0 -8.8 sodium:proton antiporter compare
MMP_RS07600 -2.9 -2.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06895 -2.9 -1.7 selenocysteine-specific translation elongation factor compare
MMP_RS04775 -2.9 -4.1 adenosylhomocysteinase compare
MMP_RS05250 -2.9 -2.2 NFYB/HAP3 family transcription factor subunit compare
MMP_RS01725 -2.9 -4.7 class I SAM-dependent methyltransferase family protein compare
MMP_RS02195 -2.9 -4.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS05430 -2.9 -5.1 TIGR00288 family NYN domain-containing protein compare
MMP_RS08350 -2.9 -1.0 hypothetical protein compare
MMP_RS05555 -2.9 -1.6 DUF4040 domain-containing protein compare
MMP_RS02885 -2.9 -17.4 molybdopterin biosynthesis protein compare
MMP_RS00110 -2.9 -3.3 hypothetical protein compare
MMP_RS03580 -2.9 -3.4 signal recognition particle-docking protein FtsY compare
MMP_RS01005 -2.9 -1.5 riboflavin synthase compare
MMP_RS06885 -2.9 -2.6 50S ribosome-binding GTPase compare
MMP_RS04585 -2.9 -10.7 AIR synthase related protein compare
MMP_RS05765 -2.9 -8.5 M42 family metallopeptidase compare
MMP_RS03145 -2.9 -7.2 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS07635 -2.9 -8.7 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS01925 -2.9 -7.4 DUF1616 domain-containing protein compare
MMP_RS06105 -2.8 -10.9 hydrogenase maturation peptidase HycI compare
MMP_RS06700 -2.8 -12.8 hypothetical protein compare
MMP_RS06175 -2.8 -6.7 winged helix-turn-helix transcriptional regulator compare
MMP_RS00985 -2.8 -5.2 CDC48 family AAA ATPase compare
MMP_RS00345 -2.8 -6.2 DUF2666 domain-containing protein compare
MMP_RS06685 -2.8 -13.9 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS00120 -2.8 -6.9 LysR family transcriptional regulator compare
MMP_RS06855 -2.7 -12.9 hypothetical protein compare
MMP_RS01900 -2.7 -14.2 hypothetical protein compare
MMP_RS01755 -2.7 -1.5 DUF2097 domain-containing protein compare
MMP_RS01905 -2.7 -10.3 glycosyltransferase compare
MMP_RS06925 -2.7 -2.7 ribonuclease VapC4 compare
MMP_RS05925 -2.7 -3.7 small nuclear ribonucleoprotein compare
MMP_RS03305 -2.7 -10.0 winged helix-turn-helix domain-containing protein compare
MMP_RS08320 -2.7 -5.6 molybdopterin molybdotransferase MoeA compare
MMP_RS08370 -2.7 -0.7 cation:proton antiporter subunit C compare
MMP_RS02875 -2.7 -9.0 chorismate pyruvate-lyase family protein compare
MMP_RS06295 -2.7 -8.2 methanogenesis marker 14 protein compare
MMP_RS06345 -2.7 -13.1 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS07445 -2.6 -8.1 helix-turn-helix domain-containing protein compare
MMP_RS06670 -2.6 -4.9 glucose-6-phosphate isomerase compare
MMP_RS06720 -2.6 -9.1 response regulator transcription factor compare
MMP_RS00335 -2.6 -5.3 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS02800 -2.6 -9.9 nucleotidyltransferase domain-containing protein compare
MMP_RS06355 -2.6 -2.9 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS05550 -2.6 -0.9 cation:proton antiporter compare
MMP_RS03685 -2.6 -9.5 Mrp/NBP35 family ATP-binding protein compare
MMP_RS06200 -2.6 -11.8 M24 family metallopeptidase compare
MMP_RS00235 -2.6 -13.8 HDIG domain-containing protein conserved
MMP_RS06715 -2.6 -16.0 cache domain-containing protein compare
MMP_RS08165 -2.6 -2.3 phosphoglycerate dehydrogenase compare
MMP_RS02235 -2.6 -10.7 CBS domain-containing protein compare
MMP_RS06860 -2.5 -2.0 4Fe-4S binding protein compare
MMP_RS00895 -2.5 -3.4 hypothetical protein compare
MMP_RS03095 -2.5 -7.4 diphthine synthase compare
MMP_RS08075 -2.5 -6.9 DUF749 domain-containing protein compare
MMP_RS08070 -2.5 -6.5 DUF2096 domain-containing protein compare
MMP_RS04780 -2.5 -3.1 ribonuclease P compare
MMP_RS05545 -2.5 -5.9 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS03140 -2.5 -11.5 hypothetical protein compare
MMP_RS06705 -2.4 -9.7 formate/nitrite transporter family protein compare
MMP_RS08690 -2.4 -10.8 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS01545 -2.4 -1.2 CBS domain-containing protein compare
MMP_RS01795 -2.4 -1.4 methanogenesis marker 6 protein compare
MMP_RS04870 -2.4 -6.1 TIGR02253 family HAD-type hydrolase compare
MMP_RS05445 -2.4 -8.7 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS01830 -2.4 -1.7 tRNA-Val compare
MMP_RS03155 -2.4 -8.0 precorrin-6A reductase compare
MMP_RS00310 -2.4 -12.6 CBS domain-containing protein compare
MMP_RS02870 -2.4 -9.8 hypothetical protein compare
MMP_RS05440 -2.3 -9.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS07685 -2.3 -8.9 TIGR01212 family radical SAM protein compare
MMP_RS04615 -2.3 -4.6 PDGLE domain-containing protein compare
MMP_RS03300 -2.3 -0.8 TOBE domain-containing protein compare
MMP_RS05425 -2.3 -5.0 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS08635 -2.3 -2.0 UbiA family prenyltransferase compare
MMP_RS05540 -2.3 -3.4 hypothetical protein compare
MMP_RS03435 -2.3 -1.8 ketol-acid reductoisomerase compare
MMP_RS00115 -2.3 -14.3 radical SAM protein compare
MMP_RS07630 -2.3 -1.2 ATP-binding cassette domain-containing protein compare
MMP_RS05795 -2.3 -3.2 redox-regulated ATPase YchF compare
MMP_RS05245 -2.3 -12.2 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS03755 -2.3 -13.3 MarR family transcriptional regulator compare
MMP_RS00750 -2.3 -2.7 fumarate hydratase compare
MMP_RS07575 -2.3 -3.7 RNA ligase partner protein compare
MMP_RS06270 -2.2 -4.9 TIGR00300 family protein compare
MMP_RS03035 -2.2 -2.9 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01335 -2.2 -2.5 prefoldin subunit beta compare
MMP_RS08645 -2.2 -7.9 UPF0179 family protein compare
MMP_RS07615 -2.2 -7.5 energy-coupling factor ABC transporter permease compare
MMP_RS04500 -2.2 -13.1 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS03445 -2.2 -1.1 methanogenesis marker 17 protein compare
MMP_RS01330 -2.2 -14.0 DHH family phosphoesterase compare
MMP_RS06120 -2.2 -2.5 UPF0147 family protein compare
MMP_RS01045 -2.2 -9.1 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS02085 -2.1 -8.3 inosine/xanthosine triphosphatase compare
MMP_RS02145 -2.1 -5.7 winged helix-turn-helix transcriptional regulator compare
MMP_RS08000 -2.1 -13.7 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS05450 -2.1 -5.5 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS06730 -2.1 -2.1 phosphopantothenate/pantothenate synthetase compare
MMP_RS09020 -2.1 -1.4 hypothetical protein compare
MMP_RS06215 -2.0 -3.0 30S ribosomal protein S6e compare
MMP_RS05420 -2.0 -5.2 DUF61 family protein compare
MMP_RS06370 -2.0 -5.4 biotin synthase BioB compare
MMP_RS05845 -2.0 -1.8 tRNA-intron lyase compare
MMP_RS00130 -2.0 -1.2 nickel-responsive transcriptional regulator NikR compare
MMP_RS00695 -2.0 -0.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00850 -2.0 -5.3 TIGR01177 family methyltransferase compare
MMP_RS07730 -2.0 -1.6 pyruvate synthase subunit beta compare
MMP_RS04875 -2.0 -3.6 energy-converting hydrogenase B subunit P compare
MMP_RS04620 -2.0 -9.4 cobalt transporter CbiM compare
MMP_RS06310 -2.0 -3.2 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS08840 -2.0 -9.4 class I SAM-dependent methyltransferase compare
MMP_RS07415 -1.9 -7.4 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS02100 -1.9 -4.1 metallophosphoesterase compare
MMP_RS02170 -1.9 -4.6 CBS domain-containing protein compare
MMP_RS03475 -1.9 -0.6 hypothetical protein compare
MMP_RS05460 -1.9 -9.0 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS03205 -1.9 -1.5 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS02190 -1.9 -3.3 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS01665 -1.9 -4.0 DUF2111 domain-containing protein compare
MMP_RS07605 -1.9 -3.9 diadenylate cyclase compare
MMP_RS05110 -1.9 -5.7 16S ribosomal RNA methyltransferase A compare
MMP_RS07365 -1.9 -9.2 2-phosphoglycerate kinase compare
MMP_RS06940 -1.9 -3.3 polyprenyl diphosphate synthase compare
MMP_RS08600 -1.9 -2.2 flagellar protein D compare
MMP_RS07385 -1.8 -2.3 protein translocase SEC61 complex subunit gamma compare
MMP_RS01960 -1.8 -0.5 hypothetical protein compare
MMP_RS00305 -1.8 -1.5 phosphoribosyl-ATP diphosphatase compare
MMP_RS01265 -1.8 -1.6 hypothetical protein compare
MMP_RS03555 -1.8 -9.1 transcriptional regulator compare
MMP_RS07750 -1.8 -3.6 DUF357 domain-containing protein compare
MMP_RS03960 -1.8 -0.9 hypothetical protein compare
MMP_RS02280 -1.8 -0.9 DUF211 domain-containing protein compare
MMP_RS03400 -1.8 -2.6 archease compare
MMP_RS02225 -1.7 -6.6 carbohydrate kinase family protein compare
MMP_RS08790 -1.7 -1.9 translation initiation factor IF-2 subunit alpha compare
MMP_RS06770 -1.7 -7.8 DHH family phosphoesterase compare
MMP_RS00475 -1.7 -8.5 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS08105 -1.7 -6.2 6-carboxyhexanoate--CoA ligase compare
MMP_RS02880 -1.7 -6.1 AmmeMemoRadiSam system radical SAM enzyme compare
MMP_RS08095 -1.7 -5.5 dethiobiotin synthase compare
MMP_RS06980 -1.7 -6.8 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS01380 -1.7 -3.1 PHP domain-containing protein compare
MMP_RS02110 -1.7 -2.1 hypothetical protein compare
MMP_RS01840 -1.7 -7.4 TIGR00289 family protein compare
MMP_RS07735 -1.7 -0.8 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06230 -1.7 -2.2 helix-turn-helix domain-containing protein compare
MMP_RS04605 -1.6 -4.2 cobalt ECF transporter T component CbiQ compare


Specific Phenotypes

For 25 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis S2

For stress Sodium hypophosphite across organisms