Experiment set15S702 for Methanococcus maripaludis S2

Compare to:

Formate 100 mM hypophosphite

200 most important genes:

  gene name fitness t score description  
MMP_RS03300 -4.5 -0.9 TOBE domain-containing protein compare
MMP_RS00305 -4.3 -1.9 phosphoribosyl-ATP diphosphatase compare
MMP_RS01970 -4.3 -10.4 TIGR04279 domain-containing protein compare
MMP_RS07555 -4.1 -0.8 monovalent cation/H+ antiporter subunit E compare
MMP_RS01880 -3.9 -7.5 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS06355 -3.9 -2.9 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS08300 -3.9 -1.3 metal-sulfur cluster assembly factor compare
MMP_RS07005 -3.9 -0.7 4Fe-4S binding protein compare
MMP_RS00295 -3.9 -2.2 gamma carbonic anhydrase family protein compare
MMP_RS02355 -3.7 -3.2 30S ribosomal protein S27ae compare
MMP_RS02900 -3.7 -0.7 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS00130 -3.6 -1.2 nickel-responsive transcriptional regulator NikR compare
MMP_RS03205 -3.6 -1.4 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS01885 -3.6 -4.9 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01910 -3.5 -5.9 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS01875 -3.5 -7.1 N-acetyltransferase compare
MMP_RS04890 -3.5 -0.9 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01545 -3.5 -1.2 CBS domain-containing protein compare
MMP_RS01915 -3.4 -9.1 DUF354 domain-containing protein compare
MMP_RS01175 -3.4 -3.8 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS02165 -3.4 -7.6 tRNA-dihydrouridine synthase compare
MMP_RS02110 -3.4 -2.2 hypothetical protein compare
MMP_RS00335 -3.3 -4.5 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS06120 -3.3 -2.3 UPF0147 family protein compare
MMP_RS06685 -3.2 -11.7 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06350 -3.2 -7.2 HesA/MoeB/ThiF family protein compare
MMP_RS01335 -3.2 -2.3 prefoldin subunit beta compare
MMP_RS01955 -3.2 -1.7 hypothetical protein compare
MMP_RS01985 -3.1 -7.6 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS01920 -3.1 -12.4 glycosyltransferase family 2 protein compare
MMP_RS01895 -3.1 -10.5 flippase compare
MMP_RS07600 -3.1 -2.3 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS07575 -3.1 -4.4 RNA ligase partner protein compare
MMP_RS02800 -3.0 -9.1 nucleotidyltransferase domain-containing protein compare
MMP_RS06295 -3.0 -7.9 methanogenesis marker 14 protein compare
MMP_RS03580 -3.0 -3.1 signal recognition particle-docking protein FtsY compare
MMP_RS05515 -3.0 -5.8 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS01725 -3.0 -3.6 class I SAM-dependent methyltransferase family protein compare
MMP_RS08785 -3.0 -1.0 RNA-protein complex protein Nop10 compare
MMP_RS07730 -3.0 -1.7 pyruvate synthase subunit beta compare
MMP_RS03145 -2.9 -5.9 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS06345 -2.9 -12.0 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS01890 -2.9 -3.5 nucleotide sugar dehydrogenase compare
MMP_RS04720 -2.9 -2.7 DedA family protein compare
MMP_RS00300 -2.9 -0.8 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS03960 -2.9 -1.0 hypothetical protein compare
MMP_RS02235 -2.9 -11.7 CBS domain-containing protein compare
MMP_RS03700 -2.9 -9.1 sodium:proton antiporter compare
MMP_RS04710 -2.9 -1.7 hypothetical protein compare
MMP_RS03600 -2.8 -2.2 triose-phosphate isomerase compare
MMP_RS06680 -2.8 -13.6 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03095 -2.8 -5.0 diphthine synthase compare
MMP_RS03305 -2.8 -9.6 winged helix-turn-helix domain-containing protein compare
MMP_RS07635 -2.8 -7.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06105 -2.7 -9.1 hydrogenase maturation peptidase HycI compare
MMP_RS07075 -2.7 -2.6 phosphomannomutase/phosphoglucomutase compare
MMP_RS04775 -2.7 -3.6 adenosylhomocysteinase compare
MMP_RS08635 -2.7 -1.7 UbiA family prenyltransferase compare
MMP_RS06700 -2.7 -12.1 hypothetical protein compare
MMP_RS06270 -2.7 -6.7 TIGR00300 family protein compare
MMP_RS03685 -2.7 -11.0 Mrp/NBP35 family ATP-binding protein compare
MMP_RS06400 -2.7 -1.6 4Fe-4S binding protein compare
MMP_RS02240 -2.7 -2.8 methanogenesis marker 7 protein compare
MMP_RS04875 -2.7 -4.7 energy-converting hydrogenase B subunit P compare
MMP_RS00345 -2.7 -6.3 DUF2666 domain-containing protein compare
MMP_RS05765 -2.7 -7.0 M42 family metallopeptidase compare
MMP_RS03015 -2.7 -11.4 GTP 3' 8-cyclase MoaA compare
MMP_RS04585 -2.7 -9.7 AIR synthase related protein compare
MMP_RS07445 -2.6 -7.7 helix-turn-helix domain-containing protein compare
MMP_RS08720 -2.6 -1.6 4Fe-4S binding protein compare
MMP_RS06720 -2.6 -9.0 response regulator transcription factor compare
MMP_RS05430 -2.6 -5.6 TIGR00288 family NYN domain-containing protein compare
MMP_RS05425 -2.6 -4.5 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS00985 -2.6 -5.6 CDC48 family AAA ATPase compare
MMP_RS02885 -2.6 -15.0 molybdopterin biosynthesis protein compare
MMP_RS07735 -2.6 -0.7 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS08070 -2.6 -6.0 DUF2096 domain-containing protein compare
MMP_RS06670 -2.6 -4.6 glucose-6-phosphate isomerase compare
MMP_RS06285 -2.6 -2.2 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS06925 -2.5 -2.0 ribonuclease VapC4 compare
MMP_RS03025 -2.5 -6.1 molybdenum cofactor guanylyltransferase compare
MMP_RS00235 -2.5 -9.8 HDIG domain-containing protein conserved
MMP_RS05250 -2.5 -1.9 NFYB/HAP3 family transcription factor subunit compare
MMP_RS06715 -2.5 -15.5 cache domain-containing protein compare
MMP_RS00310 -2.5 -11.5 CBS domain-containing protein compare
MMP_RS01830 -2.5 -1.5 tRNA-Val compare
MMP_RS04620 -2.5 -10.9 cobalt transporter CbiM compare
MMP_RS01800 -2.5 -4.2 TIGR00303 family protein compare
MMP_RS03140 -2.5 -12.8 hypothetical protein compare
MMP_RS02870 -2.4 -8.9 hypothetical protein compare
MMP_RS01005 -2.4 -1.5 riboflavin synthase compare
MMP_RS01795 -2.4 -1.6 methanogenesis marker 6 protein compare
MMP_RS06855 -2.4 -10.8 hypothetical protein compare
MMP_RS01755 -2.4 -1.3 DUF2097 domain-containing protein compare
MMP_RS03155 -2.4 -7.1 precorrin-6A reductase compare
MMP_RS06315 -2.4 -0.9 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS06885 -2.4 -2.4 50S ribosome-binding GTPase compare
MMP_RS08370 -2.4 -0.6 cation:proton antiporter subunit C compare
MMP_RS05545 -2.4 -6.1 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02280 -2.4 -0.9 DUF211 domain-containing protein compare
MMP_RS07380 -2.3 -1.7 transcription elongation factor Spt5 compare
MMP_RS00695 -2.3 -0.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS04685 -2.3 -3.0 DUF126 domain-containing protein compare
MMP_RS06200 -2.3 -9.7 M24 family metallopeptidase compare
MMP_RS01220 -2.3 -6.4 hypothetical protein compare
MMP_RS02245 -2.3 -3.1 hypothetical protein compare
MMP_RS02875 -2.3 -8.5 chorismate pyruvate-lyase family protein compare
MMP_RS04615 -2.3 -4.3 PDGLE domain-containing protein compare
MMP_RS05555 -2.3 -1.4 DUF4040 domain-containing protein compare
MMP_RS05110 -2.3 -6.8 16S ribosomal RNA methyltransferase A compare
MMP_RS05420 -2.3 -6.3 DUF61 family protein compare
MMP_RS06705 -2.3 -6.5 formate/nitrite transporter family protein compare
MMP_RS05540 -2.3 -4.7 hypothetical protein compare
MMP_RS03755 -2.2 -11.9 MarR family transcriptional regulator compare
MMP_RS06175 -2.2 -5.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS08075 -2.2 -3.5 DUF749 domain-containing protein compare
MMP_RS07580 -2.2 -2.5 DUF356 domain-containing protein compare
MMP_RS01925 -2.2 -6.1 DUF1616 domain-containing protein compare
MMP_RS01610 -2.2 -2.3 hypothetical protein compare
MMP_RS08690 -2.2 -9.2 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS05440 -2.2 -10.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS00110 -2.2 -2.5 hypothetical protein compare
MMP_RS01180 -2.2 -1.5 XTP/dITP diphosphatase compare
MMP_RS03390 -2.2 -6.0 malate dehydrogenase compare
MMP_RS02345 -2.2 -3.3 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS01905 -2.2 -8.3 glycosyltransferase compare
MMP_RS01020 -2.2 -1.0 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS05875 -2.2 -5.3 hydroxyethylthiazole kinase compare
MMP_RS08745 -2.2 -5.3 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07685 -2.2 -8.0 TIGR01212 family radical SAM protein compare
MMP_RS08455 -2.2 -4.1 multiprotein bridging factor aMBF1 compare
MMP_RS00115 -2.2 -10.7 radical SAM protein compare
MMP_RS05445 -2.1 -8.7 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS02340 -2.1 -2.2 DNA-directed RNA polymerase subunit E'' compare
MMP_RS05450 -2.1 -4.2 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS06860 -2.1 -1.6 4Fe-4S binding protein compare
MMP_RS01225 -2.1 -4.7 DUF5379 domain-containing protein compare
MMP_RS01900 -2.1 -11.6 hypothetical protein compare
MMP_RS04090 -2.1 -2.5 hypothetical protein compare
MMP_RS08820 -2.1 -5.4 hypothetical protein compare
MMP_RS02195 -2.1 -3.3 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS04870 -2.1 -3.1 TIGR02253 family HAD-type hydrolase compare
MMP_RS06730 -2.1 -1.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS01500 -2.1 -1.4 CBS domain-containing protein compare
MMP_RS00120 -2.1 -5.7 LysR family transcriptional regulator compare
MMP_RS08485 -2.1 -8.2 tungstate ABC transporter substrate-binding protein WtpA conserved
MMP_RS08320 -2.1 -6.6 molybdopterin molybdotransferase MoeA compare
MMP_RS04500 -2.1 -12.1 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS02170 -2.1 -4.4 CBS domain-containing protein compare
MMP_RS01260 -2.1 -3.9 HDIG domain-containing protein compare
MMP_RS06895 -2.0 -1.5 selenocysteine-specific translation elongation factor compare
MMP_RS08000 -2.0 -11.6 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS07845 -2.0 -1.9 LL-diaminopimelate aminotransferase compare
MMP_RS02100 -2.0 -3.3 metallophosphoesterase compare
MMP_RS05245 -2.0 -9.6 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS05925 -2.0 -2.9 small nuclear ribonucleoprotein compare
MMP_RS06370 -2.0 -3.8 biotin synthase BioB compare
MMP_RS01330 -2.0 -12.2 DHH family phosphoesterase compare
MMP_RS03400 -2.0 -2.0 archease compare
MMP_RS05460 -2.0 -9.2 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS02145 -1.9 -4.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS07615 -1.9 -6.5 energy-coupling factor ABC transporter permease compare
MMP_RS01380 -1.9 -3.7 PHP domain-containing protein compare
MMP_RS01665 -1.9 -3.8 DUF2111 domain-containing protein compare
MMP_RS08645 -1.9 -3.2 UPF0179 family protein compare
MMP_RS04605 -1.9 -3.5 cobalt ECF transporter T component CbiQ compare
MMP_RS03555 -1.9 -6.1 transcriptional regulator compare
MMP_RS08335 -1.9 -5.1 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS08165 -1.9 -2.2 phosphoglycerate dehydrogenase compare
MMP_RS00685 -1.9 -3.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07605 -1.9 -2.5 diadenylate cyclase compare
MMP_RS05795 -1.9 -4.7 redox-regulated ATPase YchF compare
MMP_RS01840 -1.9 -5.6 TIGR00289 family protein compare
MMP_RS00750 -1.9 -2.0 fumarate hydratase compare
MMP_RS03315 -1.8 -0.8 ferrous iron transport protein A compare
MMP_RS01045 -1.8 -6.7 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS01250 -1.8 -4.2 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS08210 -1.8 -1.7 phosphatidylglycerophosphatase A compare
MMP_RS03250 -1.8 -2.2 MJ1244 family protein compare
MMP_RS07625 -1.8 -2.6 cobalt ECF transporter T component CbiQ compare
MMP_RS06770 -1.8 -7.3 DHH family phosphoesterase compare
MMP_RS06215 -1.8 -2.3 30S ribosomal protein S6e compare
MMP_RS01385 -1.8 -0.6 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS03035 -1.8 -3.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01265 -1.8 -2.5 hypothetical protein compare
MMP_RS07415 -1.8 -7.1 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS09020 -1.7 -1.1 hypothetical protein compare
MMP_RS00850 -1.7 -3.0 TIGR01177 family methyltransferase compare
MMP_RS07365 -1.7 -7.3 2-phosphoglycerate kinase compare
MMP_RS06940 -1.7 -2.9 polyprenyl diphosphate synthase compare
MMP_RS08840 -1.7 -10.2 class I SAM-dependent methyltransferase compare
MMP_RS02135 -1.7 -3.4 DUF5612 domain-containing protein compare
MMP_RS06230 -1.7 -2.3 helix-turn-helix domain-containing protein compare
MMP_RS05845 -1.7 -1.3 tRNA-intron lyase compare
MMP_RS03445 -1.7 -0.9 methanogenesis marker 17 protein compare
MMP_RS06020 -1.6 -3.0 archaeoflavoprotein AfpA compare
MMP_RS02085 -1.6 -7.5 inosine/xanthosine triphosphatase compare
MMP_RS04485 -1.6 -9.2 putative beta-lysine N-acetyltransferase compare
MMP_RS08105 -1.6 -5.1 6-carboxyhexanoate--CoA ligase compare
MMP_RS01975 -1.6 -6.6 hypothetical protein compare


Specific Phenotypes

For 25 genes in this experiment

For stress Sodium hypophosphite in Methanococcus maripaludis S2

For stress Sodium hypophosphite across organisms