Experiment set15S700 for Methanococcus maripaludis S2

Compare to:

Formate 200 mM hypophosphite

200 most important genes:

  gene name fitness t score description  
MMP_RS02280 -2.8 -1.5 DUF211 domain-containing protein compare
MMP_RS01500 -2.0 -2.0 CBS domain-containing protein compare
MMP_RS02235 -2.0 -5.7 CBS domain-containing protein compare
MMP_RS08725 -1.7 -2.0 Ni/Fe hydrogenase subunit alpha compare
MMP_RS01940 -1.5 -2.1 MoxR family ATPase compare
MMP_RS07005 -1.5 -0.8 4Fe-4S binding protein compare
MMP_RS05815 -1.5 -1.8 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08715 -1.5 -1.1 formylmethanofuran dehydrogenase subunit B compare
MMP_RS03465 -1.4 -1.3 adenine phosphoribosyltransferase compare
MMP_RS05365 -1.3 -2.3 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS01325 -1.2 -1.2 dihydroneopterin aldolase family protein compare
MMP_RS06365 -1.2 -1.9 hypothetical protein compare
MMP_RS08210 -1.2 -1.4 phosphatidylglycerophosphatase A compare
MMP_RS06630 -1.2 -0.8 UPF0058 family protein compare
MMP_RS02245 -1.2 -1.9 hypothetical protein compare
MMP_RS00515 -1.1 -0.8 DUF655 domain-containing protein compare
MMP_RS05925 -1.0 -1.9 small nuclear ribonucleoprotein compare
MMP_RS04720 -1.0 -1.0 DedA family protein compare
MMP_RS04090 -1.0 -1.4 hypothetical protein compare
MMP_RS06730 -1.0 -0.9 phosphopantothenate/pantothenate synthetase compare
MMP_RS00695 -1.0 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06540 -1.0 -1.5 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS01055 -1.0 -2.7 hypothetical protein compare
MMP_RS07755 -1.0 -0.9 DUF555 domain-containing protein compare
MMP_RS08440 -0.9 -1.5 cell division protein SepF compare
MMP_RS06315 -0.9 -0.6 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS00130 -0.9 -1.0 nickel-responsive transcriptional regulator NikR compare
MMP_RS06515 -0.9 -1.6 UPF0489 family protein compare
MMP_RS01540 -0.9 -1.7 DUF504 domain-containing protein compare
MMP_RS04615 -0.9 -1.8 PDGLE domain-containing protein compare
MMP_RS01095 -0.9 -2.9 iron ABC transporter permease compare
MMP_RS00295 -0.9 -1.6 gamma carbonic anhydrase family protein compare
MMP_RS07625 -0.8 -1.7 cobalt ECF transporter T component CbiQ compare
MMP_RS05675 -0.8 -2.0 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS07350 -0.8 -1.0 preprotein translocase subunit Sec61beta compare
MMP_RS02595 -0.8 -1.0 putative zinc-binding protein compare
MMP_RS05640 -0.8 -1.2 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS07875 -0.8 -2.2 hypothetical protein compare
MMP_RS03875 -0.8 -2.2 hypothetical protein compare
MMP_RS06215 -0.8 -1.6 30S ribosomal protein S6e compare
MMP_RS01545 -0.8 -0.8 CBS domain-containing protein compare
MMP_RS07355 -0.8 -0.7 transcription factor S compare
MMP_RS01610 -0.7 -1.2 hypothetical protein compare
MMP_RS01970 -0.7 -2.0 TIGR04279 domain-containing protein compare
MMP_RS02415 -0.7 -1.2 site-specific integrase compare
MMP_RS04260 -0.7 -2.8 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS05910 -0.7 -1.9 cell division ATPase MinD compare
MMP_RS02955 -0.7 -1.3 DJ-1/PfpI family protein compare
MMP_RS01650 -0.7 -0.7 sulfurtransferase TusA family protein compare
MMP_RS02310 -0.7 -1.2 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS08745 -0.7 -1.4 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS05420 -0.7 -1.6 DUF61 family protein compare
MMP_RS02735 -0.7 -2.0 MBL fold metallo-hydrolase compare
MMP_RS00675 -0.6 -0.6 nitroreductase family protein compare
MMP_RS00450 -0.6 -0.8 4Fe-4S binding protein compare
MMP_RS06290 -0.6 -1.9 DNA repair and recombination protein RadA compare
MMP_RS01525 -0.6 -1.2 nucleoside-diphosphate kinase compare
MMP_RS01175 -0.6 -1.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS04360 -0.6 -1.8 hypothetical protein compare
MMP_RS03580 -0.6 -1.1 signal recognition particle-docking protein FtsY compare
MMP_RS02790 -0.6 -0.7 class III signal peptide-containing protein compare
MMP_RS05825 -0.6 -1.8 peptidyl-prolyl cis-trans isomerase compare
MMP_RS07895 -0.6 -1.6 cytochrome c compare
MMP_RS01880 -0.6 -1.0 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS07695 -0.6 -2.1 DUF3236 domain-containing protein compare
MMP_RS07840 -0.5 -1.4 ribonuclease III compare
MMP_RS00125 -0.5 -0.8 DUF2798 domain-containing protein compare
MMP_RS00705 -0.5 -1.3 hypothetical protein compare
MMP_RS06495 -0.5 -1.3 YkgJ family cysteine cluster protein compare
MMP_RS06175 -0.5 -1.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS08785 -0.5 -0.6 RNA-protein complex protein Nop10 compare
MMP_RS06395 -0.5 -0.6 ThiF family adenylyltransferase compare
MMP_RS01380 -0.5 -1.2 PHP domain-containing protein compare
MMP_RS05970 -0.5 -1.6 class II SORL domain-containing protein compare
MMP_RS02175 -0.5 -0.4 DUF1611 domain-containing protein compare
MMP_RS01930 -0.5 -2.8 hypothetical protein compare
MMP_RS00905 -0.5 -1.8 phenylacetate--CoA ligase compare
MMP_RS08650 -0.5 -0.6 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS02965 -0.5 -1.5 carboxymuconolactone decarboxylase family protein compare
MMP_RS08995 -0.5 -0.7 hypothetical protein compare
MMP_RS04835 -0.5 -2.0 chemotaxis protein CheC compare
MMP_RS05295 -0.5 -2.6 minichromosome maintenance protein MCM compare
MMP_RS08335 -0.5 -2.0 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS07905 -0.5 -1.7 DUF3343 domain-containing protein compare
MMP_RS06905 -0.5 -1.0 hypothetical protein compare
MMP_RS06875 -0.5 -2.3 FAD-dependent oxidoreductase compare
MMP_RS06325 -0.5 -0.7 hypothetical protein compare
MMP_RS08320 -0.5 -1.4 molybdopterin molybdotransferase MoeA compare
MMP_RS07575 -0.5 -1.2 RNA ligase partner protein compare
MMP_RS06350 -0.5 -1.4 HesA/MoeB/ThiF family protein compare
MMP_RS07900 -0.5 -0.9 YeeE/YedE family protein compare
MMP_RS00665 -0.5 -1.4 hypothetical protein compare
MMP_RS02010 -0.5 -2.4 PHP domain-containing protein compare
MMP_RS01685 -0.5 -0.8 indolepyruvate oxidoreductase subunit beta compare
MMP_RS06170 -0.5 -1.9 ABC transporter ATP-binding protein compare
MMP_RS02340 -0.4 -0.7 DNA-directed RNA polymerase subunit E'' compare
MMP_RS08990 -0.4 -2.0 hypothetical protein compare
MMP_RS03520 -0.4 -0.7 YwbE family protein compare
MMP_RS02905 -0.4 -0.8 2-thiouracil desulfurase family protein compare
MMP_RS03095 -0.4 -1.5 diphthine synthase compare
MMP_RS06460 -0.4 -0.9 pyrimidine dimer DNA glycosylase/endonuclease V compare
MMP_RS03425 -0.4 -2.0 hypothetical protein compare
MMP_RS03100 -0.4 -0.9 hypothetical protein compare
MMP_RS00060 -0.4 -0.4 3-dehydroquinate synthase II compare
MMP_RS06915 -0.4 -1.9 metallophosphoesterase compare
MMP_RS02480 -0.4 -0.9 hypothetical protein compare
MMP_RS02985 -0.4 -0.9 hypothetical protein compare
MMP_RS05285 -0.4 -1.8 MMPL family transporter compare
MMP_RS07925 -0.4 -1.4 haloacid dehalogenase compare
MMP_RS07815 -0.4 -0.6 DUF2120 domain-containing protein compare
MMP_RS01335 -0.4 -0.9 prefoldin subunit beta compare
MMP_RS00685 -0.4 -0.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01895 -0.4 -2.1 flippase compare
MMP_RS04030 -0.4 -1.8 hypothetical protein compare
MMP_RS07180 -0.4 -2.0 DEAD/DEAH box helicase compare
MMP_RS05845 -0.4 -0.4 tRNA-intron lyase compare
MMP_RS07635 -0.4 -1.6 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS04015 -0.4 -0.9 hypothetical protein compare
MMP_RS06475 -0.4 -0.8 FAD-dependent oxidoreductase compare
MMP_RS05515 -0.4 -1.8 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS08175 -0.4 -1.7 7-cyano-7-deazaguanine synthase compare
MMP_RS07860 -0.4 -0.3 hypothetical protein compare
MMP_RS04700 -0.4 -2.2 hypothetical protein compare
MMP_RS00135 -0.4 -1.5 DUF2121 domain-containing protein compare
MMP_RS02835 -0.4 -1.1 CGGC domain-containing protein compare
MMP_RS04710 -0.4 -0.4 hypothetical protein compare
MMP_RS08615 -0.4 -0.5 flagellar protein G compare
MMP_RS06980 -0.4 -1.6 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS04630 -0.4 -1.1 3'-5' exonuclease compare
MMP_RS02000 -0.4 -1.5 radical SAM protein compare
MMP_RS01260 -0.4 -1.2 HDIG domain-containing protein compare
MMP_RS01100 -0.4 -0.3 ABC transporter ATP-binding protein compare
MMP_RS03300 -0.4 -0.3 TOBE domain-containing protein compare
MMP_RS01865 -0.4 -0.6 GPR1/FUN34/YaaH family transporter compare
MMP_RS08075 -0.4 -1.1 DUF749 domain-containing protein compare
MMP_RS08410 -0.4 -1.1 DUF169 domain-containing protein compare
MMP_RS01975 -0.4 -1.1 hypothetical protein compare
MMP_RS02045 -0.4 -0.6 tRNA-Met compare
MMP_RS01445 -0.4 -1.5 hypothetical protein compare
MMP_RS07850 -0.3 -0.8 prephenate dehydratase compare
MMP_RS05635 -0.3 -1.4 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS01945 -0.3 -1.4 DUF4350 domain-containing protein compare
MMP_RS01950 -0.3 -1.8 hypothetical protein compare
MMP_RS00290 -0.3 -1.2 hypothetical protein compare
MMP_RS08845 -0.3 -1.9 archaellum operon transcriptional activator EarA family protein compare
MMP_RS00145 -0.3 -1.4 ATP-dependent Clp protease proteolytic subunit compare
MMP_RS07885 -0.3 -1.1 tripartite tricarboxylate transporter permease compare
MMP_RS00735 -0.3 -0.8 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS04520 -0.3 -1.2 nucleoside deaminase compare
MMP_RS06035 -0.3 -1.7 glycosyltransferase family 2 protein compare
MMP_RS04150 -0.3 -1.6 MFS transporter compare
MMP_RS02005 -0.3 -1.6 RNA ligase compare
MMP_RS01140 -0.3 -1.3 molybdate ABC transporter permease subunit compare
MMP_RS06335 -0.3 -0.9 HAD family hydrolase compare
MMP_RS06155 -0.3 -0.8 DUF4186 domain-containing protein compare
MMP_RS00900 -0.3 -0.4 50S ribosomal protein L39e compare
MMP_RS02135 -0.3 -0.8 DUF5612 domain-containing protein compare
MMP_RS03485 -0.3 -0.9 TIGR00267 family protein compare
MMP_RS08470 -0.3 -1.1 ATP-binding cassette domain-containing protein compare
MMP_RS01920 -0.3 -0.9 glycosyltransferase family 2 protein compare
MMP_RS04305 -0.3 -0.5 hypothetical protein compare
MMP_RS05430 -0.3 -1.5 TIGR00288 family NYN domain-containing protein compare
MMP_RS01115 -0.3 -1.4 molybdopterin molybdotransferase MoeA compare
MMP_RS02720 -0.3 -0.9 molybdate ABC transporter substrate-binding protein compare
MMP_RS08645 -0.3 -1.3 UPF0179 family protein compare
MMP_RS02995 -0.3 -1.1 acyl-CoA thioesterase compare
MMP_RS06920 -0.3 -1.8 AAA family ATPase compare
MMP_RS03800 -0.3 -0.9 hypothetical protein compare
MMP_RS04690 -0.3 -0.7 class III signal peptide-containing protein compare
MMP_RS06575 -0.3 -0.8 fluoride efflux transporter CrcB compare
MMP_RS08760 -0.3 -0.8 hypothetical protein compare
MMP_RS08365 -0.3 -0.8 energy conserving hydrogenase EhbF compare
MMP_RS06545 -0.3 -1.1 ferredoxin family protein compare
MMP_RS04315 -0.3 -1.6 corrinoid protein compare
MMP_RS02800 -0.3 -1.4 nucleotidyltransferase domain-containing protein compare
MMP_RS00385 -0.3 -1.0 P-II family nitrogen regulator compare
MMP_RS07150 -0.3 -1.0 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS03585 -0.3 -0.6 Hsp20/alpha crystallin family protein compare
MMP_RS04735 -0.3 -1.3 tautomerase family protein compare
MMP_RS03020 -0.3 -0.8 peptidylprolyl isomerase compare
MMP_RS08630 -0.3 -1.3 archaellar assembly protein FlaJ compare
MMP_RS04745 -0.3 -1.6 proteasome assembly chaperone family protein compare
MMP_RS08260 -0.3 -1.0 DUF99 family protein compare
MMP_RS00475 -0.3 -1.0 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03015 -0.3 -1.4 GTP 3' 8-cyclase MoaA compare
MMP_RS00110 -0.3 -0.5 hypothetical protein compare
MMP_RS02225 -0.3 -1.3 carbohydrate kinase family protein compare
MMP_RS06280 -0.3 -1.3 alpha-glucan family phosphorylase compare
MMP_RS05865 -0.3 -0.4 hypothetical protein compare
MMP_RS03655 -0.3 -1.4 DUF1894 domain-containing protein compare
MMP_RS08670 -0.3 -1.0 metallophosphoesterase compare
MMP_RS06005 -0.3 -0.9 heavy-metal-associated domain-containing protein compare
MMP_RS03225 -0.3 -1.1 acetolactate decarboxylase compare
MMP_RS08315 -0.3 -0.8 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS03735 -0.3 -1.7 indolepyruvate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06090 -0.3 -1.1 iron ABC transporter permease compare
MMP_RS05535 -0.3 -0.9 hypothetical protein compare
MMP_RS02815 -0.3 -0.5 hypothetical protein compare
MMP_RS00620 -0.3 -1.2 4Fe-4S binding protein compare
MMP_RS08235 -0.3 -0.9 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium hypophosphite across organisms