Experiment set15IT062 for Bacteroides thetaiotaomicron VPI-5482

Compare to:

BHIS with Trimethoprim 7.5 uM

200 most detrimental genes:

  gene name fitness t score description  
BT3928 +3.3 19.1 hypothetical protein (NCBI ptt file) compare
BT4453 +2.4 6.8 6-pyruvoyl-tetrahydropterin synthase (NCBI ptt file) compare
BT0738 +2.3 10.4 serine hydroxymethyltransferase (NCBI ptt file) compare
BT3866 +2.3 15.9 ammonium-dependent carbamoyl phosphate synthetase CarB2 (EC 6.3.4.16) (from data) compare
BT1844 +2.0 6.5 transcriptional regulator, putative iron uptake regulation protein (NCBI ptt file) compare
BT3253 +2.0 7.0 phosphoribosylamine--glycine ligase (NCBI ptt file) compare
BT0585 +1.8 2.6 conserved hypothetical protein (NCBI ptt file) compare
BT0173 +1.7 3.3 conserved hypothetical protein (NCBI ptt file) compare
BT1733 +1.7 10.5 putative phosphoribosylformylglycinamidine synthase (NCBI ptt file) compare
BT3072 +1.6 10.2 collagenase precursor (NCBI ptt file) compare
BT0880 +1.6 4.5 hypothetical protein (NCBI ptt file) compare
BT4041 +1.6 8.3 conserved hypothetical protein (NCBI ptt file) compare
BT1222 +1.6 4.0 6-phosphogluconate dehydrogenase,decarboxylating (NCBI ptt file) compare
BT3843 +1.6 8.6 ATP-dependent Clp protease ATP-binding subunit (NCBI ptt file) compare
BT1843 +1.5 7.6 adenylosuccinate synthetase (NCBI ptt file) compare
BT1112 +1.5 1.5 transposase (NCBI ptt file) compare
BT4211 +1.4 4.2 putative phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) compare
BT3213 +1.4 3.2 tRNA pseudouridine synthase B (NCBI ptt file) compare
BT0892 +1.4 1.8 dihydroorotate dehydrogenase (NCBI ptt file) compare
BT0429 +1.4 3.0 indolepyruvate oxidoreductase subunit iorB (NCBI ptt file) compare
BT1221 +1.3 4.9 glucose-6-phosphate 1-dehydrogenase (NCBI ptt file) compare
BT1229 +1.3 2.6 conserved hypothetical protein, putative membrane protein (NCBI ptt file) compare
BT1747 +1.3 7.4 pyruvate-flavodoxin oxidoreductase (NCBI ptt file) compare
BT4531 +1.3 6.6 conserved hypothetical protein (NCBI ptt file) compare
BT4582 +1.2 8.3 amidophosphoribosyltransferase precursor (NCBI ptt file) compare
BT0923 +1.2 3.0 putative periplasmic protein (NCBI ptt file) compare
BT2142 +1.2 2.4 conserved hypothetical protein, with a conserved domain (NCBI ptt file) compare
BT0704 +1.2 2.6 phosphoribosylglycinamide formyltransferase 2 (NCBI ptt file) compare
BT0696 +1.2 5.0 putative membrane protein (NCBI ptt file) compare
BT0596 +1.1 1.6 putative transcriptional regulator (NCBI ptt file) compare
BT0912 +1.1 2.7 DNA-binding protein HU (NCBI ptt file) compare
BT2161 +1.1 4.0 50S ribosomal protein L9 (NCBI ptt file) compare
BT0185 +1.1 1.4 conserved hypothetical protein (NCBI ptt file) compare
BT0549 +1.1 2.6 putative thioredoxin (NCBI ptt file) compare
BT0544 +1.1 3.0 ammonium transporter (NCBI ptt file) compare
BT4191 +1.1 8.6 hypothetical protein (NCBI ptt file) compare
BT1220 +1.1 3.3 6-phosphogluconolactonase (NCBI ptt file) compare
BT4556 +1.0 2.5 hypothetical protein (NCBI ptt file) compare
BT0428 +1.0 3.6 phenylacetate-coenzyme A ligase (NCBI ptt file) compare
BT2006 +1.0 1.9 hypothetical protein (NCBI ptt file) compare
BT3915 +1.0 1.9 hypothetical protein (NCBI ptt file) compare
BT4533 +1.0 6.5 conserved hypothetical protein (NCBI ptt file) compare
BT3840 +1.0 3.0 putative RNA-binding protein rbpA (NCBI ptt file) compare
BT4529 +1.0 2.5 hypothetical protein (NCBI ptt file) compare
BT3232 +1.0 2.0 gluconate 5-dehydrogenase (NCBI ptt file) compare
BT1656 +1.0 1.3 putative transcriptional regulator (NCBI ptt file) compare
BT1380 +1.0 2.4 imidazole glycerol phosphate synthase subunit hisH (NCBI ptt file) compare
BT4532 +1.0 3.1 hypothetical protein (NCBI ptt file) compare
BT1746 +0.9 1.6 conserved hypothetical protein (NCBI ptt file) compare
BT1524 +0.9 1.8 hypothetical protein (NCBI ptt file) compare
BT4339 +0.9 2.4 glutamine synthetase (NCBI ptt file) compare
BT4569 +0.9 2.8 hypothetical protein (NCBI ptt file) compare
BT4524 +0.9 3.1 conserved hypothetical protein (NCBI ptt file) compare
BT0739 +0.9 2.7 hypothetical protein (NCBI ptt file) compare
BT1186 +0.9 1.9 ABC transporter ATP-binding protein (NCBI ptt file) compare
BT1203 +0.9 2.3 putative UDP-N-acetylglucosamine 2-epimerase (NCBI ptt file) compare
BT0528 +0.9 2.6 phosphoribosylanthranilate isomerase (EC 5.3.1.24) (from data) compare
BT0418 +0.9 2.4 outer membrane porin F precursor (NCBI ptt file) compare
BT0877 +0.9 1.9 ferredoxin domain containing protein (NCBI ptt file) compare
BT0199 +0.8 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT1933 +0.8 1.8 transposase (NCBI ptt file) compare
BT1104 +0.8 0.9 small heat shock protein (NCBI ptt file) compare
BT3211 +0.8 1.1 conserved hypothetical protein (NCBI ptt file) compare
BT0517 +0.8 2.5 flavodoxin (NCBI ptt file) compare
BT2742 +0.8 0.7 integrase, site-specific recombinase (NCBI ptt file) compare
BT4503 +0.8 2.1 conserved hypothetical protein (NCBI ptt file) compare
BT2449 +0.8 1.6 hypothetical protein (NCBI ptt file) compare
BT0016 +0.8 2.8 hypothetical protein (NCBI ptt file) compare
BT1232 +0.8 1.2 hypothetical protein (NCBI ptt file) compare
BT2121 +0.8 4.4 putative Na+-driven multidrug efflux pump (NCBI ptt file) compare
BT0758 +0.8 1.5 acetyltransferase (NCBI ptt file) compare
BT0635 +0.8 2.4 putative transcriptional regulator (NCBI ptt file) compare
BT0085 +0.8 2.2 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT1854 +0.8 1.3 putative membrane-associated phospholipid phosphatase (NCBI ptt file) compare
BT4206 +0.8 1.4 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (NCBI ptt file) compare
BT3865 +0.8 2.2 hypothetical protein (NCBI ptt file) compare
BT2417 +0.8 1.3 conserved hypothetical protein (NCBI ptt file) compare
BT3911 +0.8 2.3 malate dehydrogenase (NCBI ptt file) compare
BT1915 +0.8 2.7 pyruvate carboxylase subunit A (NCBI ptt file) compare
BT1313 +0.8 2.0 muconate cycloisomerase (NCBI ptt file) compare
BT3209 +0.8 2.9 conserved hypothetical protein (NCBI ptt file) compare
BT3979 +0.7 2.0 putative methyltransferase (NCBI ptt file) compare
BT3812 +0.7 2.5 phosphoribosylaminoimidazole carboxy formyl formyltransferase; inosine-monophosphate cyclohydrolase; bifunctional purine biosynthesis protein purH (NCBI ptt file) compare
BT0327 +0.7 1.7 glutamine ABC transporter, periplasmic glutamine-binding protein (glnH) (NCBI ptt file) compare
BT1107 +0.7 1.4 ferritin A (NCBI ptt file) compare
BT4002 +0.7 1.2 ATPase, ParA family (NCBI ptt file) compare
BT2339 +0.7 2.2 conserved hypothetical protein (NCBI ptt file) compare
BT0911 +0.7 3.0 putative integration host factor IHF alpha subunit (NCBI ptt file) compare
BT4098 +0.7 1.3 Trk system K+ uptake protein trkA (NCBI ptt file) compare
BT1394 +0.7 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT3318 +0.7 3.3 signal peptidase I (NCBI ptt file) compare
BT2275 +0.7 3.1 thymidine kinase (NCBI ptt file) compare
BT1808 +0.7 1.9 conserved hypothetical protein (NCBI ptt file) compare
BT1494 +0.7 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT3229 +0.7 1.5 TatD-related DNase (NCBI ptt file) compare
BT4530 +0.7 3.8 ATP-dependent DNA helicase recG (NCBI ptt file) compare
BT3231 +0.7 2.9 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (NCBI ptt file) compare
BT3303 +0.7 4.2 ATP-dependent RNA helicase (NCBI ptt file) compare
BT4561 +0.7 2.1 conserved hypothetical protein, putative integral membrane protein (NCBI ptt file) compare
BT2168 +0.6 3.5 coproporphyrinogen III oxidase (NCBI ptt file) compare
BT1855 +0.6 1.8 putative methyl transferase (NCBI ptt file) compare
BT1395 +0.6 2.2 conserved hypothetical protein (NCBI ptt file) compare
BT0847 +0.6 2.0 hypothetical protein (NCBI ptt file) compare
BT1728 +0.6 3.0 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT0018 +0.6 1.9 hypothetical protein (NCBI ptt file) compare
BT2134 +0.6 2.5 putative HD superfamily hydrolase (NCBI ptt file) compare
BT1976 +0.6 1.2 hypothetical protein (NCBI ptt file) compare
BT2141 +0.6 2.3 putative N-acetylmuramoyl-L-alanine amidase amiA (NCBI ptt file) compare
BT3415 +0.6 2.3 hypothetical protein (NCBI ptt file) compare
BT4700 +0.6 1.5 isochorismate synthase entC (NCBI ptt file) compare
BT0638 +0.6 1.5 putative methionine aminopeptidase A (NCBI ptt file) compare
BT1916 +0.6 2.8 conserved hypothetical protein (NCBI ptt file) compare
BT2274 +0.6 3.1 hypothetical protein (NCBI ptt file) compare
BT3268 +0.6 1.2 glucose-inhibited division protein A (NCBI ptt file) compare
BT4466 +0.6 1.4 hypothetical protein (NCBI ptt file) compare
BT1921 +0.6 2.4 hypothetical protein (NCBI ptt file) compare
BT1943 +0.6 2.4 hypothetical protein (NCBI ptt file) compare
BT0545 +0.6 1.4 nitrogen regulatory protein P-II (NCBI ptt file) compare
BT0568 +0.6 3.1 hypothetical protein (NCBI ptt file) compare
BT2542 +0.6 2.6 putative haloacid dehalogenase-like hydrolase (NCBI ptt file) compare
BT1905 +0.6 1.6 conserved hypothetical protein (NCBI ptt file) compare
BT3320 +0.6 3.1 dihydrodipicolinate reductase (NCBI ptt file) compare
BT1130 +0.6 0.9 hypothetical protein (NCBI ptt file) compare
BT2974 +0.6 1.3 hypothetical protein (NCBI ptt file) compare
BT0853 +0.6 2.3 putative methyltransferase (NCBI ptt file) compare
BT3369 +0.6 1.4 putative glycosyltransferase (NCBI ptt file) compare
BT0319 +0.6 1.2 hypothetical protein (NCBI ptt file) compare
BT3267 +0.6 2.8 adenine phosphoribosyltransferase (NCBI ptt file) compare
BT0783 +0.6 1.2 hypothetical protein (NCBI ptt file) compare
BT3323 +0.6 2.1 hypothetical protein (NCBI ptt file) compare
BT1752 +0.6 1.1 hypothetical protein (NCBI ptt file) compare
BT0820 +0.6 1.6 conserved hypothetical protein (NCBI ptt file) compare
BT4720 +0.6 2.7 putative RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT0869 +0.6 1.0 hypothetical protein (NCBI ptt file) compare
BT0582 +0.6 1.1 conserved hypothetical protein (NCBI ptt file) compare
BT4382 +0.6 2.5 hypothetical protein (NCBI ptt file) compare
BT3772 +0.6 1.0 ribosomal large subunit pseudouridine synthase D (NCBI ptt file) compare
BT1153 +0.6 3.4 phosphoserine aminotransferase (NCBI ptt file) compare
BT2973 +0.6 2.9 transcriptional regulator (NCBI ptt file) compare
BT0736 +0.6 1.9 putative transport protein (NCBI ptt file) compare
BT1217 +0.6 1.8 two-component system response regulator (NCBI ptt file) compare
BT0058 +0.6 2.2 hypothetical protein (NCBI ptt file) compare
BT1084 +0.6 1.6 hypothetical protein (NCBI ptt file) compare
BT2115 +0.6 1.8 hypothetical protein (NCBI ptt file) compare
BT1050 +0.6 2.2 hypothetical protein (NCBI ptt file) compare
BT1986 +0.6 2.2 putative ribose 5-phosphate isomerase (NCBI ptt file) compare
BT1868 +0.6 1.2 conserved hypothetical protein (NCBI ptt file) compare
BT0056 +0.6 2.5 putative glycosyltransferase (NCBI ptt file) compare
BT3165 +0.6 2.8 tRNA/rRNA methyltransferase (NCBI ptt file) compare
BT2127 +0.6 2.8 putative beta-phosphoglucomutase (NCBI ptt file) compare
BT0098 +0.6 0.8 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT1698 +0.6 1.0 conserved hypothetical protein (NCBI ptt file) compare
BT1374 +0.6 3.0 diaminopimelate decarboxylase (EC 4.1.1.20) (from data) compare
BT4702 +0.6 1.2 dihydroxynapthoic acid synthetase (NCBI ptt file) compare
BT3022 +0.6 0.9 hypothetical protein (NCBI ptt file) compare
BT0339 +0.6 2.1 alpha-glucosidase (NCBI ptt file) compare
BT4490 +0.6 1.4 hypothetical protein (NCBI ptt file) compare
BT4360 +0.5 3.4 hypothetical protein (NCBI ptt file) compare
BT0033 +0.5 1.2 hypothetical protein (NCBI ptt file) compare
BT0310 +0.5 1.8 lipoate-protein ligase A (NCBI ptt file) compare
BT2348 +0.5 1.8 conserved hypothetical protein, IS related (NCBI ptt file) compare
BT2280 +0.5 1.4 hypothetical protein (NCBI ptt file) compare
BT1615 +0.5 2.7 aminoacyl-histidine dipeptidase (NCBI ptt file) compare
BT1201 +0.5 1.4 conserved hypothetical protein (NCBI ptt file) compare
BT2685 +0.5 1.5 hypothetical protein (NCBI ptt file) compare
BT4765 +0.5 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT3614 +0.5 2.3 putative oxidoreductase (NCBI ptt file) compare
BT3980 +0.5 0.9 hypothetical protein (NCBI ptt file) compare
BT1539 +0.5 1.8 cytidine deaminase (NCBI ptt file) compare
BT0913 +0.5 1.7 putative Fe-S oxidoreductase (NCBI ptt file) compare
BT0231 +0.5 0.9 excisionase (NCBI ptt file) compare
BT0249 +0.5 1.0 5-methyltetrahydrofolate--homocysteine methyltransferase or methionine synthase (NCBI ptt file) compare
BT0930 +0.5 1.3 hypothetical protein (NCBI ptt file) compare
BT2799 +0.5 2.2 putative PfkB family carbohydrate kinase (NCBI ptt file) compare
BT0785 +0.5 3.1 glutamine synthetase I (NCBI ptt file) compare
BT2689 +0.5 2.2 conserved hypothetical protein (NCBI ptt file) compare
BT1152 +0.5 1.8 D-3-phosphoglycerate dehydrogenase (NCBI ptt file) compare
BT0902 +0.5 1.2 hypothetical protein (NCBI ptt file) compare
BT1009 +0.5 1.2 dihydroorotate dehydrogenase (NCBI ptt file) compare
BT1320 +0.5 2.2 putative transcriptional regulator, phosphate uptake regulation (NCBI ptt file) compare
BT4618 +0.5 1.5 conserved hypothetical protein (NCBI ptt file) compare
BT0067 +0.5 1.0 hypothetical protein (NCBI ptt file) compare
BT4141 +0.5 2.1 hypothetical protein (NCBI ptt file) compare
BT4193 +0.5 3.6 dipeptidyl peptidase IV (NCBI ptt file) compare
BT2059 +0.5 0.7 TonB (NCBI ptt file) compare
BT2688 +0.5 1.3 outer membrane efflux protein (NCBI ptt file) compare
BT0073 +0.5 2.3 putative ABC transporter, ATP-binding protein (NCBI ptt file) compare
BT4285 +0.5 2.2 hypothetical protein (NCBI ptt file) compare
BT3438 +0.5 1.2 hypothetical protein (NCBI ptt file) compare
BT1326 +0.5 0.8 TPR-domain containing protein (NCBI ptt file) compare
BT3491 +0.5 1.8 glutaminase A (NCBI ptt file) compare
BT0618 +0.5 0.8 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfC (NCBI ptt file) compare
BT4557 +0.5 2.8 hypothetical protein (NCBI ptt file) compare
BT0543 +0.5 2.0 glutamine synthetase (NCBI ptt file) compare
BT3443 +0.5 1.7 conserved hypothetical protein with a conserved domain (NCBI ptt file) compare
BT4030 +0.5 2.4 hypothetical protein (NCBI ptt file) compare
BT1988 +0.5 2.2 hypothetical protein (NCBI ptt file) compare
BT0153 +0.5 1.5 hypothetical protein (NCBI ptt file) compare
BT1252 +0.5 1.5 hypothetical protein (NCBI ptt file) compare
BT2340 +0.5 1.5 conserved hypothetical protein (NCBI ptt file) compare


Specific Phenotypes

For 1 genes in this experiment

For stress Trimethoprim in Bacteroides thetaiotaomicron VPI-5482

For stress Trimethoprim across organisms