Experiment set15H19 for Pseudomonas stutzeri RCH2

Compare to:

LB with Nalidixic acid sodium salt 0.00390625 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Psest_0740 +13.0 18.4 Transcriptional regulator compare
Psest_0790 +2.3 1.4 Uncharacterized protein conserved in bacteria compare
Psest_1292 +2.2 10.5 monothiol glutaredoxin, Grx4 family compare
Psest_0969 +2.2 3.8 transcription elongation factor GreA compare
Psest_2001 +2.2 1.4 2-phosphoglycolate phosphatase, prokaryotic compare
Psest_1235 +2.2 6.0 Leucyl aminopeptidase compare
Psest_3575 +2.1 3.8 Arabinose efflux permease compare
Psest_4078 +2.1 3.7 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D compare
Psest_1947 +2.1 1.9 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_2585 +2.0 1.3 pseudouridylate synthase I compare
Psest_1144 +2.0 3.7 AmpG-related permease compare
Psest_0320 +1.9 3.4 ABC-type multidrug transport system, ATPase component compare
Psest_3400 +1.9 2.3 Copper resistance protein D. compare
Psest_3664 +1.9 2.4 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_3926 +1.9 11.6 GTP-binding protein TypA/BipA compare
Psest_1804 +1.8 3.2 Superfamily II DNA and RNA helicases compare
Psest_0307 +1.8 6.8 Cytochrome B561 compare
Psest_1879 +1.8 3.9 Trk-type K+ transport systems, membrane components compare
Psest_0999 +1.8 3.4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_2643 +1.8 3.2 Beta-glucosidase-related glycosidases compare
Psest_2857 +1.7 9.0 Rad3-related DNA helicases conserved
Psest_2724 +1.7 1.3 hypothetical protein compare
Psest_1496 +1.6 1.6 Holliday junction DNA helicase, RuvA subunit compare
Psest_0296 +1.6 6.1 glutathione synthetase, prokaryotic compare
Psest_0031 +1.6 3.3 Uncharacterized conserved protein compare
Psest_1853 +1.5 2.2 MoxR-like ATPases compare
Psest_1505 +1.5 2.5 Organic radical activating enzymes compare
Psest_2719 +1.5 2.9 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_2101 +1.5 1.7 hypothetical protein compare
Psest_1815 +1.5 8.2 pseudaminic acid synthase compare
Psest_3927 +1.5 4.1 thiazole biosynthesis/tRNA modification protein ThiI compare
Psest_1242 +1.5 2.2 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_2344 +1.5 3.0 Methyl-accepting chemotaxis protein compare
Psest_0417 +1.4 2.5 Acyl-CoA dehydrogenases compare
Psest_3185 +1.4 1.7 MoxR-like ATPases compare
Psest_2756 +1.4 1.8 hypothetical protein compare
Psest_0321 +1.4 7.7 Predicted membrane protein compare
Psest_2778 +1.4 2.1 Parvulin-like peptidyl-prolyl isomerase compare
Psest_2944 +1.4 0.9 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_2409 +1.3 1.7 Serine/threonine protein phosphatase compare
Psest_0298 +1.3 3.2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0526 +1.3 1.0 hypothetical protein compare
Psest_2613 +1.3 1.6 hypothetical protein compare
Psest_2018 +1.3 2.3 Uncharacterized conserved protein compare
Psest_1999 +1.3 1.0 pseudouridine synthase compare
Psest_1763 +1.3 2.7 hypothetical protein compare
Psest_2288 +1.3 2.6 trigger factor compare
Psest_0175 +1.3 4.4 Xaa-Pro aminopeptidase compare
Psest_1037 +1.3 1.9 acetolactate synthase, small subunit compare
Psest_3367 +1.3 1.9 translation initation factor SUI1, putative, prokaryotic compare
Psest_1563 +1.3 1.9 Protein of unknown function (DUF548). compare
Psest_1029 +1.3 2.3 Regulator of competence-specific genes compare
Psest_0609 +1.3 2.2 hypothetical protein compare
Psest_1506 +1.3 5.0 queuosine biosynthesis protein QueC compare
Psest_3960 +1.2 2.1 3'(2'),5'-bisphosphate nucleotidase, bacterial compare
Psest_1179 +1.2 0.9 2-hydroxy-3-oxopropionate reductase compare
Psest_1997 +1.2 1.7 6-phosphogluconolactonase compare
Psest_1986 +1.2 1.1 3-phosphoshikimate 1-carboxyvinyltransferase compare
Psest_3890 +1.2 1.4 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_3670 +1.2 7.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
Psest_2875 +1.2 3.6 DNA mismatch repair protein MutS compare
Psest_4393 +1.2 4.0 Capsule polysaccharide export protein compare
Psest_3123 +1.2 1.8 dihydroorotase, homodimeric type compare
Psest_3060 +1.2 2.7 hypothetical protein compare
Psest_1550 +1.2 1.8 conserved hypothetical protein compare
Psest_1167 +1.2 1.1 hypothetical protein compare
Psest_2322 +1.2 3.1 Transcriptional regulators compare
Psest_3637 +1.2 0.8 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases compare
Psest_1013 +1.2 2.8 phosphoribosylamine--glycine ligase compare
Psest_1302 +1.2 2.7 Predicted thioesterase compare
Psest_3415 +1.2 8.2 hypothetical protein compare
Psest_0734 +1.1 4.2 RND family efflux transporter, MFP subunit compare
Psest_2091 +1.1 1.4 Molecular chaperone (small heat shock protein) compare
Psest_3014 +1.1 1.5 cob(I)alamin adenosyltransferase compare
Psest_2675 +1.1 1.7 Predicted membrane-bound metal-dependent hydrolases compare
Psest_0095 +1.1 2.1 phosphonate C-P lyase system protein PhnH compare
Psest_1134 +1.1 1.9 alkyl hydroperoxide reductase, F subunit compare
Psest_1434 +1.1 3.4 NADPH:quinone reductase and related Zn-dependent oxidoreductases compare
Psest_1474 +1.1 2.8 phosphoribosylaminoimidazole synthetase compare
Psest_2648 +1.1 1.8 hypothetical protein compare
Psest_0853 +1.1 2.1 6-phosphogluconolactonase compare
Psest_2906 +1.1 1.8 tRNA_Thr_CGT compare
Psest_0662 +1.1 1.2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_2911 +1.1 1.6 Protein of unknown function (DUF2945). compare
Psest_1082 +1.1 1.0 Enoyl-CoA hydratase/carnithine racemase compare
Psest_3159 +1.1 4.2 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_1282 +1.1 1.0 Amidases related to nicotinamidase compare
Psest_1139 +1.0 2.4 PAS domain S-box compare
Psest_3961 +1.0 3.8 NTP pyrophosphohydrolases including oxidative damage repair enzymes compare
Psest_2285 +1.0 1.9 ATP-dependent protease La compare
Psest_1161 +1.0 1.8 E3 Ubiquitin ligase. compare
Psest_1805 +1.0 1.3 integration host factor, beta subunit compare
Psest_3087 +1.0 3.0 Transcriptional regulator compare
Psest_3860 +1.0 1.3 Predicted permeases compare
Psest_0409 +1.0 2.2 Putative homoserine kinase type II (protein kinase fold) compare
Psest_2230 +1.0 2.5 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes compare
Psest_2278 +1.0 1.9 coenzyme PQQ biosynthesis protein PqqD compare
Psest_3377 +1.0 1.0 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_3474 +1.0 2.4 Short-chain dehydrogenases of various substrate specificities compare
Psest_0020 +1.0 2.9 K+ transport systems, NAD-binding component compare
Psest_1543 +1.0 1.8 Predicted transcription regulator, contains HTH domain (MarR family) compare
Psest_3478 +0.9 0.8 Cytochrome B561 compare
Psest_1382 +0.9 2.9 Transcription elongation factor compare
Psest_1974 +0.9 2.0 integration host factor, alpha subunit compare
Psest_1643 +0.9 0.8 hypothetical protein compare
Psest_0414 +0.9 1.7 biotin biosynthesis protein BioC compare
Psest_4088 +0.9 2.5 Transcriptional regulators compare
Psest_1952 +0.9 2.4 hypothetical protein compare
Psest_1498 +0.9 1.0 tol-pal system-associated acyl-CoA thioesterase compare
Psest_1078 +0.9 2.0 acetyl-CoA:acetoacetate CoA transferase, A subunit (EC 2.8.3.8) (from data) compare
Psest_1635 +0.9 7.1 Signal transduction histidine kinase compare
Psest_3237 +0.9 1.3 hypothetical protein compare
Psest_4314 +0.9 2.6 ABC-type metal ion transport system, ATPase component compare
Psest_3780 +0.9 2.4 Transcriptional regulator compare
Psest_1295 +0.9 2.9 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_2624 +0.9 1.5 hypothetical protein compare
Psest_0516 +0.9 3.9 D-alanyl-D-alanine carboxypeptidase compare
Psest_2775 +0.9 2.0 Glycerol-3-phosphate dehydrogenase compare
Psest_3031 +0.9 0.5 hypothetical protein compare
Psest_2276 +0.9 2.0 Aldehyde dehydrogenase (EC 1.2.1.3) (from data) compare
Psest_0207 +0.9 2.4 hypothetical protein compare
Psest_4364 +0.9 2.4 16S rRNA (guanine(527)-N(7))-methyltransferase GidB compare
Psest_3190 +0.9 2.6 pyruvate kinase compare
Psest_2698 +0.9 1.5 benzoate 1,2-dioxygenase, small subunit compare
Psest_1665 +0.9 2.5 hypothetical protein compare
Psest_3222 +0.9 1.9 Putative threonine efflux protein compare
Psest_1954 +0.9 1.7 hypothetical protein compare
Psest_0805 +0.9 1.1 hypothetical protein compare
Psest_0133 +0.8 0.9 type VI secretion protein, VC_A0107 family compare
Psest_4330 +0.8 1.6 Protein of unknown function (DUF2909). compare
Psest_2730 +0.8 2.0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_3371 +0.8 4.7 type IV pilus modification protein PilV compare
Psest_1431 +0.8 1.4 hypothetical protein compare
Psest_2764 +0.8 0.7 hypothetical protein compare
Psest_3155 +0.8 2.0 hypothetical protein compare
Psest_1704 +0.8 0.8 Dehydrogenases (flavoproteins) compare
Psest_2442 +0.8 1.2 hypothetical protein compare
Psest_2428 +0.8 1.7 hypothetical protein compare
Psest_1852 +0.8 1.9 Uncharacterized conserved protein compare
Psest_3702 +0.8 2.3 Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase compare
Psest_1259 +0.8 2.4 23S rRNA m2A2503 methyltransferase compare
Psest_3513 +0.8 1.2 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (from data) compare
Psest_3189 +0.8 1.3 hypothetical protein compare
Psest_1241 +0.8 3.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
Psest_1801 +0.8 3.1 3-deoxy-7-phosphoheptulonate synthase, class II compare
Psest_2950 +0.8 1.4 putative NAD(P)H quinone oxidoreductase, PIG3 family compare
Psest_2976 +0.8 0.7 hypothetical protein compare
Psest_4286 +0.8 4.2 Glutamine synthetase compare
Psest_2483 +0.8 1.7 Predicted redox protein, regulator of disulfide bond formation compare
Psest_1304 +0.8 3.3 Nucleotidyltransferase/DNA polymerase involved in DNA repair compare
Psest_1121 +0.8 3.6 Hypoxanthine-guanine phosphoribosyltransferase compare
Psest_1070 +0.8 1.7 Predicted membrane protein compare
Psest_2748 +0.8 0.7 Transcriptional regulator compare
Psest_1313 +0.8 0.7 Uncharacterized conserved small protein compare
Psest_1691 +0.8 1.1 aminodeoxychorismate lyase compare
Psest_0902 +0.8 2.4 Predicted transcriptional regulators compare
Psest_4324 +0.8 2.3 DNA repair photolyase compare
Psest_3700 +0.8 1.0 hypothetical protein compare
Psest_2969 +0.8 2.1 Methylase of chemotaxis methyl-accepting proteins compare
Psest_1424 +0.8 1.4 Lipoate-protein ligase A compare
Psest_1293 +0.8 0.8 VanZ like family. compare
Psest_1775 +0.7 1.5 Predicted ATPase (AAA+ superfamily) compare
Psest_4273 +0.7 3.5 Lysophospholipase compare
Psest_0831 +0.7 0.7 hypothetical protein compare
Psest_3296 +0.7 0.7 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain compare
Psest_2863 +0.7 2.8 Transcriptional regulator compare
Psest_4280 +0.7 1.5 ABC-type spermidine/putrescine transport system, permease component II compare
Psest_3048 +0.7 0.9 hypothetical protein compare
Psest_3416 +0.7 3.9 Predicted ATPase (AAA+ superfamily) compare
Psest_2405 +0.7 0.8 NAD-dependent protein deacetylases, SIR2 family compare
Psest_2441 +0.7 2.8 hypothetical protein compare
Psest_0587 +0.7 1.1 Domain of Unknown Function (DUF326). compare
Psest_0660 +0.7 1.3 Methyl-accepting chemotaxis protein compare
Psest_0511 +0.7 0.7 rRNA large subunit m3Psi methyltransferase RlmH compare
Psest_1877 +0.7 1.0 AraC-type DNA-binding domain-containing proteins compare
Psest_2630 +0.7 1.5 hypothetical protein compare
Psest_3712 +0.7 2.8 Type II secretory pathway, component ExeA (predicted ATPase) compare
Psest_0732 +0.7 1.6 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_2061 +0.7 1.6 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Psest_2470 +0.7 1.0 hypothetical protein compare
Psest_3563 +0.7 1.7 ABC-type transport system, involved in lipoprotein release, permease component compare
Psest_1197 +0.7 2.5 Ureidoglycolate hydrolase compare
Psest_2248 +0.7 0.8 Predicted transcriptional regulators compare
Psest_3230 +0.7 2.3 Uncharacterized conserved protein compare
Psest_3662 +0.7 1.0 DnaJ-domain-containing proteins 1 compare
Psest_0151 +0.7 1.7 Response regulator with putative antiterminator output domain compare
Psest_0279 +0.7 2.6 methionine biosynthesis protein MetW compare
Psest_3413 +0.7 1.5 hypothetical protein compare
Psest_1587 +0.7 2.6 hypothetical protein compare
Psest_3998 +0.7 2.5 glutamate--cysteine ligase compare
Psest_3013 +0.7 1.0 cobyrinic acid a,c-diamide synthase compare
Psest_2671 +0.7 0.8 Transcriptional regulator compare
Psest_2056 +0.7 2.6 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_3500 +0.7 1.2 Acetyltransferases, including N-acetylases of ribosomal proteins compare
Psest_3813 +0.7 2.3 ribonuclease PH compare
Psest_2370 +0.7 1.5 Protein of unknown function (DUF1652). compare
Psest_3219 +0.7 2.2 Zn-dependent hydrolases, including glyoxylases compare
Psest_4271 +0.7 2.5 Predicted proline hydroxylase compare
Psest_2918 +0.7 1.5 amino acid ABC transporter substrate-binding protein, PAAT family (TC 3.A.1.3.-) compare
Psest_3314 +0.7 2.1 ribosomal subunit interface protein compare


Specific Phenotypes

For 4 genes in this experiment

For stress Nalidixic acid sodium salt in Pseudomonas stutzeri RCH2

For stress Nalidixic acid sodium salt across organisms