Experiment set14S759 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete no stress control

200 most important genes:

  gene name fitness t score description  
MMP_RS06285 -5.4 -2.3 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS03315 -5.0 -1.4 ferrous iron transport protein A compare
MMP_RS01385 -5.0 -0.8 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS02900 -4.9 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS05920 -4.3 -0.7 50S ribosomal protein L37e compare
MMP_RS09020 -4.2 -1.8 hypothetical protein compare
MMP_RS04780 -4.2 -3.7 ribonuclease P compare
MMP_RS08635 -4.2 -2.2 UbiA family prenyltransferase compare
MMP_RS01325 -4.2 -2.3 dihydroneopterin aldolase family protein compare
MMP_RS02280 -4.2 -0.9 DUF211 domain-containing protein compare
MMP_RS04775 -4.1 -4.1 adenosylhomocysteinase compare
MMP_RS06885 -4.0 -2.8 50S ribosome-binding GTPase compare
MMP_RS08820 -3.7 -5.6 hypothetical protein compare
MMP_RS08720 -3.6 -1.6 4Fe-4S binding protein compare
MMP_RS01020 -3.6 -1.0 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07845 -3.6 -1.9 LL-diaminopimelate aminotransferase compare
MMP_RS01005 -3.5 -1.4 riboflavin synthase compare
MMP_RS07635 -3.3 -7.6 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06625 -3.3 -2.2 DNA primase compare
MMP_RS08790 -3.2 -2.6 translation initiation factor IF-2 subunit alpha compare
MMP_RS06400 -3.0 -1.7 4Fe-4S binding protein compare
MMP_RS01500 -3.0 -2.3 CBS domain-containing protein compare
MMP_RS06730 -3.0 -2.0 phosphopantothenate/pantothenate synthetase compare
MMP_RS04685 -2.9 -3.3 DUF126 domain-containing protein compare
MMP_RS03600 -2.9 -2.3 triose-phosphate isomerase compare
MMP_RS04890 -2.9 -0.9 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS08645 -2.9 -9.3 UPF0179 family protein compare
MMP_RS04585 -2.8 -10.5 AIR synthase related protein compare
MMP_RS08460 -2.8 -2.4 proteasome-activating nucleotidase compare
MMP_RS07445 -2.7 -7.2 helix-turn-helix domain-containing protein compare
MMP_RS08300 -2.7 -1.2 metal-sulfur cluster assembly factor compare
MMP_RS00320 -2.7 -1.9 class I SAM-dependent methyltransferase compare
MMP_RS02175 -2.7 -0.9 DUF1611 domain-containing protein compare
MMP_RS01175 -2.6 -3.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06630 -2.6 -0.8 UPF0058 family protein compare
MMP_RS03035 -2.5 -4.0 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01700 -2.5 -1.1 dihydroxy-acid dehydratase compare
MMP_RS03445 -2.5 -1.0 methanogenesis marker 17 protein compare
MMP_RS08715 -2.5 -1.6 formylmethanofuran dehydrogenase subunit B compare
MMP_RS01610 -2.5 -2.3 hypothetical protein compare
MMP_RS07525 -2.4 -7.9 4Fe-4S binding protein compare
MMP_RS03640 -2.4 -2.5 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06975 -2.4 -2.4 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS05845 -2.3 -1.7 tRNA-intron lyase compare
MMP_RS01225 -2.3 -4.1 DUF5379 domain-containing protein compare
MMP_RS06120 -2.3 -1.9 UPF0147 family protein compare
MMP_RS03960 -2.3 -0.9 hypothetical protein compare
MMP_RS00895 -2.3 -4.4 hypothetical protein compare
MMP_RS00675 -2.3 -1.0 nitroreductase family protein compare
MMP_RS07200 -2.2 -6.2 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05430 -2.2 -3.8 TIGR00288 family NYN domain-containing protein compare
MMP_RS02165 -2.2 -7.7 tRNA-dihydrouridine synthase compare
MMP_RS06895 -2.1 -1.5 selenocysteine-specific translation elongation factor compare
MMP_RS07545 -2.1 -0.9 HTH domain-containing protein compare
MMP_RS02875 -2.1 -9.5 chorismate pyruvate-lyase family protein compare
MMP_RS03580 -2.1 -2.9 signal recognition particle-docking protein FtsY compare
MMP_RS02195 -2.1 -2.3 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS01335 -2.1 -2.3 prefoldin subunit beta compare
MMP_RS06110 -2.1 -3.2 ATP-dependent protease LonB compare
MMP_RS00115 -2.0 -11.0 radical SAM protein compare
MMP_RS06295 -2.0 -4.3 methanogenesis marker 14 protein compare
MMP_RS01755 -2.0 -1.1 DUF2097 domain-containing protein compare
MMP_RS07620 -2.0 -5.1 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS06020 -2.0 -3.5 archaeoflavoprotein AfpA compare
MMP_RS01380 -2.0 -4.3 PHP domain-containing protein compare
MMP_RS07625 -2.0 -3.6 cobalt ECF transporter T component CbiQ compare
MMP_RS00685 -1.9 -3.6 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07390 -1.9 -2.0 cell division protein FtsZ compare
MMP_RS03555 -1.9 -8.3 transcriptional regulator compare
MMP_RS07600 -1.9 -1.5 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS03025 -1.9 -4.9 molybdenum cofactor guanylyltransferase compare
MMP_RS07380 -1.8 -2.2 transcription elongation factor Spt5 compare
MMP_RS05265 -1.8 -2.0 2-isopropylmalate synthase compare
MMP_RS07765 -1.8 -7.7 sodium:alanine symporter family protein compare
MMP_RS07615 -1.7 -5.2 energy-coupling factor ABC transporter permease compare
MMP_RS00300 -1.7 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06680 -1.6 -8.2 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS04870 -1.6 -3.6 TIGR02253 family HAD-type hydrolase compare
MMP_RS07425 -1.6 -5.4 GTP-binding protein compare
MMP_RS01545 -1.6 -0.9 CBS domain-containing protein compare
MMP_RS06855 -1.6 -6.8 hypothetical protein compare
MMP_RS00305 -1.6 -1.6 phosphoribosyl-ATP diphosphatase compare
MMP_RS05245 -1.6 -7.5 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS01250 -1.6 -6.1 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS01800 -1.6 -1.8 TIGR00303 family protein compare
MMP_RS00110 -1.5 -2.2 hypothetical protein compare
MMP_RS07750 -1.5 -5.2 DUF357 domain-containing protein compare
MMP_RS07685 -1.5 -5.3 TIGR01212 family radical SAM protein compare
MMP_RS07580 -1.5 -2.0 DUF356 domain-containing protein compare
MMP_RS05545 -1.5 -4.0 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS06725 -1.5 -4.0 hypothetical protein compare
MMP_RS05865 -1.4 -3.3 hypothetical protein compare
MMP_RS01720 -1.4 -1.0 replication factor C large subunit compare
MMP_RS06230 -1.4 -1.8 helix-turn-helix domain-containing protein compare
MMP_RS01980 -1.4 -8.3 trimeric intracellular cation channel family protein compare
MMP_RS06215 -1.4 -1.5 30S ribosomal protein S6e compare
MMP_RS02345 -1.4 -2.6 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS07775 -1.4 -4.0 alanine dehydrogenase compare
MMP_RS08435 -1.4 -1.9 Era-like GTP-binding protein compare
MMP_RS07605 -1.4 -2.3 diadenylate cyclase compare
MMP_RS01265 -1.3 -1.1 hypothetical protein compare
MMP_RS05510 -1.3 -4.1 Rrf2 family transcriptional regulator compare
MMP_RS01985 -1.3 -3.7 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS05815 -1.3 -1.1 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS02240 -1.3 -1.4 methanogenesis marker 7 protein compare
MMP_RS00730 -1.3 -3.3 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS06340 -1.3 -6.2 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS02190 -1.3 -2.2 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS00295 -1.3 -1.3 gamma carbonic anhydrase family protein compare
MMP_RS06685 -1.2 -6.1 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS00695 -1.2 -0.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00725 -1.2 -3.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS06270 -1.2 -2.3 TIGR00300 family protein compare
MMP_RS07755 -1.2 -0.6 DUF555 domain-containing protein compare
MMP_RS04850 -1.2 -7.1 UPF0254 family protein compare
MMP_RS02805 -1.2 -1.1 HEPN domain-containing protein compare
MMP_RS08595 -1.2 -0.9 flagellar protein C compare
MMP_RS00735 -1.1 -3.3 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS06475 -1.1 -1.8 FAD-dependent oxidoreductase compare
MMP_RS00315 -1.1 -3.8 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS00130 -1.1 -0.9 nickel-responsive transcriptional regulator NikR compare
MMP_RS00620 -1.1 -3.6 4Fe-4S binding protein compare
MMP_RS06015 -1.1 -6.5 flavodoxin family protein compare
MMP_RS04985 -1.1 -3.3 DUF2180 family protein compare
MMP_RS06200 -1.1 -4.6 M24 family metallopeptidase compare
MMP_RS08200 -1.1 -7.8 archaeosine synthase subunit alpha compare
MMP_RS05515 -1.1 -4.6 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06315 -1.1 -0.6 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08600 -1.1 -1.8 flagellar protein D compare
MMP_RS01840 -1.1 -4.5 TIGR00289 family protein compare
MMP_RS07365 -1.1 -5.6 2-phosphoglycerate kinase compare
MMP_RS03305 -1.0 -3.3 winged helix-turn-helix domain-containing protein compare
MMP_RS06865 -1.0 -1.6 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS08915 -1.0 -1.6 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS05765 -1.0 -2.7 M42 family metallopeptidase compare
MMP_RS04955 -1.0 -2.5 DNA topoisomerase I compare
MMP_RS05540 -1.0 -1.7 hypothetical protein compare
MMP_RS08165 -1.0 -1.3 phosphoglycerate dehydrogenase compare
MMP_RS02100 -1.0 -2.2 metallophosphoesterase compare
MMP_RS04090 -1.0 -1.5 hypothetical protein compare
MMP_RS00290 -1.0 -4.0 hypothetical protein compare
MMP_RS06930 -1.0 -4.7 MBL fold metallo-hydrolase compare
MMP_RS04990 -1.0 -3.9 aquaporin family protein compare
MMP_RS03095 -1.0 -2.8 diphthine synthase compare
MMP_RS03205 -1.0 -0.8 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS01600 -0.9 -1.4 50S ribosomal protein L15e compare
MMP_RS06925 -0.9 -0.8 ribonuclease VapC4 compare
MMP_RS03110 -0.9 -2.3 glycosyltransferase family 2 protein compare
MMP_RS07700 -0.9 -4.7 DUF1188 domain-containing protein compare
MMP_RS00310 -0.9 -5.4 CBS domain-containing protein compare
MMP_RS03490 -0.9 -1.2 DUF2115 domain-containing protein compare
MMP_RS05095 -0.9 -3.3 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS07880 -0.9 -4.1 AAA family ATPase compare
MMP_RS01180 -0.9 -0.7 XTP/dITP diphosphatase compare
MMP_RS00810 -0.9 -3.9 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS06700 -0.9 -4.7 hypothetical protein compare
MMP_RS01795 -0.9 -0.7 methanogenesis marker 6 protein compare
MMP_RS00040 -0.9 -2.1 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS01220 -0.9 -2.9 hypothetical protein compare
MMP_RS00050 -0.9 -3.8 AarF/UbiB family protein compare
MMP_RS00720 -0.9 -3.2 metal-dependent hydrolase compare
MMP_RS02170 -0.9 -2.5 CBS domain-containing protein compare
MMP_RS07535 -0.9 -4.4 4Fe-4S binding protein compare
MMP_RS01665 -0.9 -2.0 DUF2111 domain-containing protein compare
MMP_RS06395 -0.8 -2.4 ThiF family adenylyltransferase compare
MMP_RS01830 -0.8 -0.9 tRNA-Val compare
MMP_RS02985 -0.8 -1.8 hypothetical protein compare
MMP_RS02025 -0.8 -4.4 DNA-directed DNA polymerase compare
MMP_RS08290 -0.8 -2.8 DNA-binding protein Alba compare
MMP_RS07575 -0.8 -1.8 RNA ligase partner protein compare
MMP_RS01365 -0.8 -1.4 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS03400 -0.8 -1.0 archease compare
MMP_RS03350 -0.8 -1.7 winged helix-turn-helix domain-containing protein compare
MMP_RS06600 -0.8 -0.7 class III signal peptide-containing protein compare
MMP_RS03020 -0.8 -2.0 peptidylprolyl isomerase compare
MMP_RS06175 -0.8 -3.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS04980 -0.8 -4.4 DUF2193 domain-containing protein compare
MMP_RS06095 -0.8 -4.0 ABC transporter ATP-binding protein compare
MMP_RS08225 -0.8 -3.9 RimK family alpha-L-glutamate ligase compare
MMP_RS00705 -0.8 -0.9 hypothetical protein compare
MMP_RS00825 -0.8 -1.9 fumarylacetoacetate hydrolase family protein compare
MMP_RS06935 -0.8 -3.4 protease complex subunit PrcB family protein compare
MMP_RS05080 -0.7 -4.0 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS00985 -0.7 -2.0 CDC48 family AAA ATPase compare
MMP_RS08570 -0.7 -4.4 coenzyme F420-0:L-glutamate ligase compare
MMP_RS03210 -0.7 -4.6 tRNA guanosine(15) transglycosylase TgtA compare
MMP_RS07815 -0.7 -0.8 DUF2120 domain-containing protein compare
MMP_RS06105 -0.7 -3.0 hydrogenase maturation peptidase HycI compare
MMP_RS05020 -0.7 -1.1 hypothetical protein compare
MMP_RS08555 -0.7 -1.5 hypothetical protein compare
MMP_RS06355 -0.7 -0.8 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS03450 -0.7 -0.9 glycine synthesis protein GlyXS (from data) compare
MMP_RS07005 -0.7 -0.3 4Fe-4S binding protein compare
MMP_RS00570 -0.7 -0.9 protein-L-isoaspartate O-methyltransferase compare
MMP_RS01780 -0.7 -2.6 TrmJ/YjtD family RNA methyltransferase compare
MMP_RS05100 -0.7 -4.8 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS05800 -0.7 -2.8 B12-binding domain-containing radical SAM protein compare
MMP_RS02145 -0.7 -1.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS02940 -0.7 -3.1 TatD family hydrolase compare
MMP_RS03875 -0.7 -1.3 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in no stress control experiments