Experiment set14S755 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS06730		-5.9	-1.4	phosphopantothenate/pantothenate synthetase
MMP_RS00320		-5.4	-0.9	class I SAM-dependent methyltransferase
MMP_RS08715		-5.3	-1.3	formylmethanofuran dehydrogenase subunit B
MMP_RS06230		-5.2	-1.7	helix-turn-helix domain-containing protein
MMP_RS08650		-5.1	-2.6	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS01175		-5.0	-2.5	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06600		-4.9	-0.8	class III signal peptide-containing protein
MMP_RS01385		-4.6	-0.6	imidazole glycerol phosphate synthase subunit HisH
MMP_RS08460		-4.5	-2.2	proteasome-activating nucleotidase
MMP_RS02900		-4.5	-0.5	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS01005		-4.4	-0.8	riboflavin synthase
MMP_RS04775		-4.3	-2.9	adenosylhomocysteinase
MMP_RS03640		-4.2	-2.9	archaeal proteasome endopeptidase complex subunit beta
MMP_RS08300		-4.2	-0.9	metal-sulfur cluster assembly factor
MMP_RS07005		-4.2	-0.5	4Fe-4S binding protein
MMP_RS00515		-4.1	-0.7	DUF655 domain-containing protein
MMP_RS05920		-4.0	-0.5	50S ribosomal protein L37e
MMP_RS00300		-4.0	-0.5	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS09025		-3.9	-0.8	hypothetical protein
MMP_RS00685		-3.7	-2.8	2-phospho-L-lactate guanylyltransferase
MMP_RS00110		-3.6	-2.6	hypothetical protein
MMP_RS03435		-3.6	-1.6	ketol-acid reductoisomerase
MMP_RS05265		-3.6	-2.2	2-isopropylmalate synthase
MMP_RS04890		-3.6	-0.6	adenylyltransferase/cytidyltransferase family protein
MMP_RS07380		-3.6	-2.0	transcription elongation factor Spt5
MMP_RS05845		-3.6	-1.4	tRNA-intron lyase
MMP_RS07755		-3.5	-0.8	DUF555 domain-containing protein
MMP_RS00305		-3.4	-1.6	phosphoribosyl-ATP diphosphatase
MMP_RS06020		-3.4	-3.7	archaeoflavoprotein AfpA
MMP_RS03400		-3.4	-1.9	archease
MMP_RS08645		-3.4	-5.1	UPF0179 family protein
MMP_RS01755		-3.2	-0.8	DUF2097 domain-containing protein
MMP_RS03600		-3.2	-1.8	triose-phosphate isomerase
MMP_RS04685		-3.2	-2.3	DUF126 domain-containing protein
MMP_RS01020		-3.1	-0.7	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS03025		-3.1	-4.3	molybdenum cofactor guanylyltransferase
MMP_RS08210		-3.1	-1.5	phosphatidylglycerophosphatase A
MMP_RS08350		-3.1	-0.8	hypothetical protein
MMP_RS08790		-3.0	-1.8	translation initiation factor IF-2 subunit alpha
MMP_RS03300		-3.0	-0.6	TOBE domain-containing protein
MMP_RS05930		-3.0	-1.6	3-isopropylmalate dehydratase large subunit
MMP_RS07735		-3.0	-0.5	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS03315		-2.9	-1.0	ferrous iron transport protein A
MMP_RS06895		-2.9	-1.1	selenocysteine-specific translation elongation factor
MMP_RS07600		-2.8	-1.7	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS06120		-2.8	-1.6	UPF0147 family protein
MMP_RS08820		-2.8	-3.8	hypothetical protein
MMP_RS09020		-2.8	-1.1	hypothetical protein
MMP_RS07445		-2.6	-5.7	helix-turn-helix domain-containing protein
MMP_RS02165		-2.6	-6.3	tRNA-dihydrouridine synthase
MMP_RS02240		-2.5	-1.6	methanogenesis marker 7 protein
MMP_RS01500		-2.5	-1.3	CBS domain-containing protein
MMP_RS04585		-2.4	-8.8	AIR synthase related protein
MMP_RS06625		-2.4	-1.3	DNA primase
MMP_RS01225		-2.4	-3.7	DUF5379 domain-containing protein
MMP_RS03580		-2.4	-2.0	signal recognition particle-docking protein FtsY
MMP_RS06295		-2.4	-3.6	methanogenesis marker 14 protein
MMP_RS06400		-2.4	-1.0	4Fe-4S binding protein
MMP_RS02875		-2.4	-4.7	chorismate pyruvate-lyase family protein
MMP_RS07390		-2.4	-1.7	cell division protein FtsZ
MMP_RS05550		-2.4	-0.5	cation:proton antiporter
MMP_RS06340		-2.3	-4.4	phosphoadenosine phosphosulfate reductase family protein
MMP_RS03205		-2.3	-1.0	peptidyl-tRNA hydrolase Pth2
MMP_RS07525		-2.3	-6.3	4Fe-4S binding protein
MMP_RS00730		-2.3	-3.8	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS06630		-2.2	-0.5	UPF0058 family protein
MMP_RS02280		-2.1	-0.6	DUF211 domain-containing protein
MMP_RS03960		-2.1	-0.6	hypothetical protein
MMP_RS01380		-2.1	-2.6	PHP domain-containing protein
MMP_RS00900		-2.1	-1.1	50S ribosomal protein L39e
MMP_RS06725		-2.1	-3.7	hypothetical protein
MMP_RS05245		-2.1	-6.9	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS01800		-2.1	-2.1	TIGR00303 family protein
MMP_RS07200		-2.0	-3.6	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS02480		-2.0	-1.6	hypothetical protein
MMP_RS00735		-2.0	-2.7	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS07425		-2.0	-3.4	GTP-binding protein
MMP_RS05250		-1.9	-2.5	NFYB/HAP3 family transcription factor subunit
MMP_RS04090		-1.9	-1.7	hypothetical protein
MMP_RS07625		-1.9	-2.3	cobalt ECF transporter T component CbiQ
MMP_RS06015		-1.9	-3.8	flavodoxin family protein
MMP_RS07385		-1.9	-1.8	protein translocase SEC61 complex subunit gamma
MMP_RS00115		-1.8	-7.6	radical SAM protein
MMP_RS08635		-1.8	-1.2	UbiA family prenyltransferase
MMP_RS07620		-1.8	-2.7	energy-coupling factor ABC transporter substrate-binding protein
MMP_RS07635		-1.8	-2.1	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS07605		-1.8	-1.9	diadenylate cyclase
MMP_RS03385		-1.8	-0.7	cation diffusion facilitator family transporter
MMP_RS00810		-1.8	-4.0	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS05430		-1.7	-2.3	TIGR00288 family NYN domain-containing protein
MMP_RS08280		-1.7	-1.9	proteasome assembly chaperone family protein
MMP_RS05765		-1.7	-3.1	M42 family metallopeptidase
MMP_RS06475		-1.7	-3.0	FAD-dependent oxidoreductase
MMP_RS03465		-1.7	-0.9	adenine phosphoribosyltransferase
MMP_RS03445		-1.7	-0.6	methanogenesis marker 17 protein
MMP_RS01335		-1.6	-1.5	prefoldin subunit beta
MMP_RS03555		-1.6	-4.5	transcriptional regulator
MMP_RS08600		-1.6	-1.1	flagellar protein D
MMP_RS00895		-1.6	-2.2	hypothetical protein
MMP_RS01600		-1.6	-1.6	50S ribosomal protein L15e
MMP_RS03450		-1.6	-1.5	glycine synthesis protein GlyXS (from data)
MMP_RS05545		-1.6	-2.8	pyridoxal phosphate-dependent aminotransferase
MMP_RS08435		-1.5	-1.3	Era-like GTP-binding protein
MMP_RS06285		-1.5	-1.1	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS06110		-1.5	-1.8	ATP-dependent protease LonB
MMP_RS00315		-1.5	-3.3	Nif3-like dinuclear metal center hexameric protein
MMP_RS03035		-1.5	-2.2	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS00725		-1.5	-3.5	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS05815		-1.5	-1.1	NOL1/NOP2/sun family putative RNA methylase
MMP_RS02495		-1.5	-1.3	hypothetical protein
MMP_RS07615		-1.5	-3.3	energy-coupling factor ABC transporter permease
MMP_RS06200		-1.5	-4.8	M24 family metallopeptidase
MMP_RS01980		-1.5	-6.0	trimeric intracellular cation channel family protein
MMP_RS00850		-1.5	-3.1	TIGR01177 family methyltransferase
MMP_RS08165		-1.5	-1.4	phosphoglycerate dehydrogenase
MMP_RS01250		-1.5	-5.0	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS06325		-1.4	-0.9	hypothetical protein
MMP_RS02815		-1.4	-1.2	hypothetical protein
MMP_RS03305		-1.4	-3.0	winged helix-turn-helix domain-containing protein
MMP_RS01610		-1.4	-1.0	hypothetical protein
MMP_RS05875		-1.4	-1.6	hydroxyethylthiazole kinase
MMP_RS06855		-1.4	-4.6	hypothetical protein
MMP_RS07730		-1.4	-1.0	pyruvate synthase subunit beta
MMP_RS05835		-1.4	-0.4	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS04985		-1.4	-4.0	DUF2180 family protein
MMP_RS04850		-1.3	-7.4	UPF0254 family protein
MMP_RS04485		-1.3	-4.4	putative beta-lysine N-acetyltransferase
MMP_RS01985		-1.3	-3.1	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS02235		-1.3	-4.4	CBS domain-containing protein
MMP_RS06975		-1.3	-1.1	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS07685		-1.3	-4.4	TIGR01212 family radical SAM protein
MMP_RS07700		-1.2	-4.7	DUF1188 domain-containing protein
MMP_RS07365		-1.2	-4.6	2-phosphoglycerate kinase
MMP_RS02245		-1.2	-1.8	hypothetical protein
MMP_RS02145		-1.2	-2.7	winged helix-turn-helix transcriptional regulator
MMP_RS02190		-1.2	-1.4	sulfopyruvate decarboxylase subunit alpha
MMP_RS07875		-1.2	-1.7	hypothetical protein
MMP_RS05830		-1.2	-2.2	peptidyl-prolyl cis-trans isomerase
MMP_RS03910		-1.2	-1.4	hypothetical protein
MMP_RS00430		-1.2	-1.9	hypothetical protein
MMP_RS07775		-1.2	-3.4	alanine dehydrogenase
MMP_RS01720		-1.2	-1.0	replication factor C large subunit
MMP_RS08200		-1.2	-6.6	archaeosine synthase subunit alpha
MMP_RS01435		-1.2	-2.8	DMT family transporter
MMP_RS07575		-1.2	-2.2	RNA ligase partner protein
MMP_RS06270		-1.2	-1.9	TIGR00300 family protein
MMP_RS07860		-1.1	-0.3	hypothetical protein
MMP_RS04980		-1.1	-5.5	DUF2193 domain-containing protein
MMP_RS05540		-1.1	-1.5	hypothetical protein
MMP_RS00040		-1.1	-3.3	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS01570		-1.1	-0.8	hypothetical protein
MMP_RS02170		-1.1	-1.5	CBS domain-containing protein
MMP_RS03800		-1.1	-1.7	hypothetical protein
MMP_RS08195		-1.1	-4.0	hypothetical protein
MMP_RS03145		-1.1	-2.4	fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
MMP_RS07880		-1.1	-3.9	AAA family ATPase
MMP_RS06585		-1.0	-0.8	DMT family protein
MMP_RS04870		-1.0	-1.6	TIGR02253 family HAD-type hydrolase
MMP_RS06155		-1.0	-1.3	DUF4186 domain-containing protein
MMP_RS00050		-1.0	-2.9	AarF/UbiB family protein
MMP_RS00570		-1.0	-1.0	protein-L-isoaspartate O-methyltransferase
MMP_RS06920		-1.0	-3.9	AAA family ATPase
MMP_RS01445		-1.0	-3.1	hypothetical protein
MMP_RS01655		-1.0	-0.9	DsrE family protein
MMP_RS01420		-1.0	-1.0	hypothetical protein
MMP_RS05070		-1.0	-2.5	4Fe-4S dicluster domain-containing protein
MMP_RS03350		-1.0	-2.2	winged helix-turn-helix domain-containing protein
MMP_RS06930		-1.0	-3.5	MBL fold metallo-hydrolase
MMP_RS08370		-1.0	-0.3	cation:proton antiporter subunit C
MMP_RS02745		-1.0	-0.7	hypothetical protein
MMP_RS06885		-1.0	-1.0	50S ribosome-binding GTPase
MMP_RS07540		-1.0	-1.4	CBS domain-containing protein
MMP_RS02675		-1.0	-1.1	hypothetical protein
MMP_RS00720		-1.0	-2.8	metal-dependent hydrolase
MMP_RS05700		-1.0	-3.5	TfuA-related McrA-glycine thioamidation protein
MMP_RS03680		-1.0	-3.7	hypothetical protein
MMP_RS02410		-1.0	-1.2	ABC transporter substrate-binding protein
MMP_RS08675		-0.9	-1.1	class III signal peptide-containing protein
MMP_RS01260		-0.9	-1.2	HDIG domain-containing protein
MMP_RS00185		-0.9	-4.4	potassium channel protein
MMP_RS01575		-0.9	-2.2	aldolase
MMP_RS01195		-0.9	-0.5	metalloregulator ArsR/SmtB family transcription factor
MMP_RS01700		-0.9	-0.4	dihydroxy-acid dehydratase
MMP_RS05365		-0.9	-0.7	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
MMP_RS03325		-0.9	-2.2	hypothetical protein
MMP_RS00665		-0.9	-1.9	hypothetical protein
MMP_RS03470		-0.9	-3.3	phosphoadenosine phosphosulfate reductase family protein
MMP_RS06175		-0.9	-2.2	winged helix-turn-helix transcriptional regulator
MMP_RS00295		-0.9	-0.8	gamma carbonic anhydrase family protein
MMP_RS01325		-0.8	-0.6	dihydroneopterin aldolase family protein
MMP_RS05020		-0.8	-1.6	hypothetical protein
MMP_RS07750		-0.8	-1.6	DUF357 domain-containing protein
MMP_RS02940		-0.8	-2.3	TatD family hydrolase
MMP_RS03490		-0.8	-0.7	DUF2115 domain-containing protein
MMP_RS08225		-0.8	-2.7	RimK family alpha-L-glutamate ligase
MMP_RS01745		-0.8	-2.2	AMP phosphorylase
MMP_RS08570		-0.8	-2.7	coenzyme F420-0:L-glutamate ligase
MMP_RS07115		-0.8	-2.2	MBL fold metallo-hydrolase
MMP_RS07845		-0.8	-0.5	LL-diaminopimelate aminotransferase
MMP_RS05100		-0.8	-5.1	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress 3-nitroxypropanol across organisms