Experiment set14S750 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete sodium bromide 250 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS01370 +3.0 9.7 acetate--CoA ligase family protein compare
MMP_RS07415 +2.3 8.7 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS02885 +2.1 15.8 molybdopterin biosynthesis protein compare
MMP_RS04720 +2.0 1.6 DedA family protein compare
MMP_RS08440 +1.8 1.6 cell division protein SepF compare
MMP_RS01890 +1.7 3.9 nucleotide sugar dehydrogenase compare
MMP_RS08320 +1.6 6.4 molybdopterin molybdotransferase MoeA compare
MMP_RS05640 +1.5 3.8 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS01875 +1.5 5.0 N-acetyltransferase compare
MMP_RS07075 +1.5 2.1 phosphomannomutase/phosphoglucomutase compare
MMP_RS00750 +1.3 1.7 fumarate hydratase compare
MMP_RS01970 +1.3 6.2 TIGR04279 domain-containing protein compare
MMP_RS06310 +1.3 2.3 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS03300 +1.2 1.1 TOBE domain-containing protein compare
MMP_RS06840 +1.2 1.3 DNA-directed RNA polymerase subunit N compare
MMP_RS07850 +1.2 3.6 prephenate dehydratase compare
MMP_RS01880 +1.2 2.8 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS03320 +1.2 2.8 metal-dependent transcriptional regulator compare
MMP_RS04695 +1.2 3.6 selenide water dikinase SelD compare
MMP_RS08445 +1.2 2.0 DUF2099 family protein compare
MMP_RS07860 +1.1 0.8 hypothetical protein compare
MMP_RS07955 +1.1 4.4 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06670 +1.1 2.2 glucose-6-phosphate isomerase compare
MMP_RS01885 +1.1 2.6 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01910 +1.1 4.4 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS01540 +1.1 3.0 DUF504 domain-containing protein compare
MMP_RS08310 +1.0 2.2 TMEM165/GDT1 family protein compare
MMP_RS07125 +1.0 2.4 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS01675 +1.0 1.8 hypothetical protein compare
MMP_RS07960 +1.0 5.4 sugar phosphate isomerase/epimerase compare
MMP_RS01945 +1.0 4.2 DUF4350 domain-containing protein compare
MMP_RS01920 +1.0 4.7 glycosyltransferase family 2 protein compare
MMP_RS08275 +1.0 5.0 hypothetical protein compare
MMP_RS04605 +0.9 2.0 cobalt ECF transporter T component CbiQ compare
MMP_RS06130 +0.9 1.9 peptidylprolyl isomerase compare
MMP_RS03675 +0.9 6.2 RimK family alpha-L-glutamate ligase compare
MMP_RS07555 +0.9 0.7 monovalent cation/H+ antiporter subunit E compare
MMP_RS00120 +0.9 3.0 LysR family transcriptional regulator compare
MMP_RS06545 +0.9 3.9 ferredoxin family protein compare
MMP_RS01900 +0.9 4.3 hypothetical protein compare
MMP_RS04690 +0.9 2.5 class III signal peptide-containing protein compare
MMP_RS01925 +0.9 2.9 DUF1616 domain-containing protein compare
MMP_RS07645 +0.9 3.5 aldehyde dehydrogenase family protein compare
MMP_RS02965 +0.9 1.9 carboxymuconolactone decarboxylase family protein compare
MMP_RS04620 +0.9 5.0 cobalt transporter CbiM compare
MMP_RS05315 +0.9 1.6 hypothetical protein compare
MMP_RS06705 +0.8 2.3 formate/nitrite transporter family protein compare
MMP_RS02790 +0.8 1.1 class III signal peptide-containing protein compare
MMP_RS06715 +0.8 5.4 cache domain-containing protein compare
MMP_RS03895 +0.8 1.9 hypothetical protein compare
MMP_RS06530 +0.8 2.9 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS04790 +0.8 4.9 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS01955 +0.8 1.6 hypothetical protein compare
MMP_RS00395 +0.8 1.4 MGMT family protein compare
MMP_RS02880 +0.8 3.0 AmmeMemoRadiSam system radical SAM enzyme compare
MMP_RS01525 +0.8 1.5 nucleoside-diphosphate kinase compare
MMP_RS09055 +0.8 0.8 CAP domain-containing protein compare
MMP_RS06720 +0.8 3.0 response regulator transcription factor compare
MMP_RS02870 +0.8 4.0 hypothetical protein compare
MMP_RS04615 +0.8 1.3 PDGLE domain-containing protein compare
MMP_RS02840 +0.8 1.5 DUF123 domain-containing protein compare
MMP_RS07890 +0.7 1.9 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS06365 +0.7 1.4 hypothetical protein compare
MMP_RS04145 +0.7 1.4 hypothetical protein compare
MMP_RS00660 +0.7 3.4 alkaline phosphatase family protein compare
MMP_RS01930 +0.7 3.9 hypothetical protein compare
MMP_RS07705 +0.7 3.0 transcriptional regulator compare
MMP_RS01915 +0.7 3.7 DUF354 domain-containing protein compare
MMP_RS05950 +0.7 2.5 nickel-dependent hydrogenase large subunit compare
MMP_RS08390 +0.7 2.8 DUF5400 domain-containing protein compare
MMP_RS02805 +0.7 0.9 HEPN domain-containing protein compare
MMP_RS01975 +0.7 4.0 hypothetical protein compare
MMP_RS01935 +0.7 3.5 DUF58 domain-containing protein compare
MMP_RS08595 +0.7 0.6 flagellar protein C compare
MMP_RS06335 +0.7 1.8 HAD family hydrolase compare
MMP_RS06495 +0.7 2.0 YkgJ family cysteine cluster protein compare
MMP_RS07095 +0.7 2.7 PspC domain-containing protein compare
MMP_RS07925 +0.7 2.7 haloacid dehalogenase compare
MMP_RS05110 +0.7 2.5 16S ribosomal RNA methyltransferase A compare
MMP_RS01320 +0.7 1.3 hypothetical protein compare
MMP_RS00675 +0.7 0.6 nitroreductase family protein compare
MMP_RS06745 +0.7 2.0 DUF2119 domain-containing protein compare
MMP_RS06500 +0.6 3.0 ATP-binding protein compare
MMP_RS06575 +0.6 2.4 fluoride efflux transporter CrcB compare
MMP_RS02675 +0.6 1.2 hypothetical protein compare
MMP_RS01905 +0.6 3.1 glycosyltransferase compare
MMP_RS03385 +0.6 0.6 cation diffusion facilitator family transporter compare
MMP_RS06940 +0.6 0.5 polyprenyl diphosphate synthase compare
MMP_RS03405 +0.6 1.7 RNA 3'-terminal phosphate cyclase compare
MMP_RS02895 +0.6 2.7 DHH family phosphoesterase compare
MMP_RS03215 +0.6 2.9 MBL fold metallo-hydrolase compare
MMP_RS01990 +0.6 1.9 hypothetical protein compare
MMP_RS01855 +0.6 2.9 2-hydroxyacyl-CoA dehydratase family protein compare
MMP_RS08360 +0.6 1.3 hypothetical protein compare
MMP_RS01065 +0.6 3.8 alpha/beta hydrolase compare
MMP_RS07130 +0.6 2.8 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS07915 +0.6 3.3 DUF4870 domain-containing protein compare
MMP_RS08350 +0.6 0.5 hypothetical protein compare
MMP_RS06485 +0.5 0.5 zinc ribbon domain-containing protein compare
MMP_RS07120 +0.5 3.3 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS05275 +0.5 2.5 AI-2E family transporter compare
MMP_RS03485 +0.5 1.3 TIGR00267 family protein compare
MMP_RS08345 +0.5 3.1 4Fe-4S binding protein compare
MMP_RS06285 +0.5 0.6 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS03820 +0.5 2.3 EamA family transporter compare
MMP_RS06610 +0.5 1.1 DUF2334 domain-containing protein compare
MMP_RS00345 +0.5 2.0 DUF2666 domain-containing protein compare
MMP_RS06325 +0.5 0.8 hypothetical protein compare
MMP_RS00975 +0.5 3.3 HD domain-containing protein compare
MMP_RS04105 +0.5 2.5 MarR family transcriptional regulator compare
MMP_RS01950 +0.5 2.4 hypothetical protein compare
MMP_RS03150 +0.5 2.7 phosphoglycerate mutase compare
MMP_RS00565 +0.5 1.4 CBS domain-containing protein compare
MMP_RS03080 +0.5 0.7 universal stress protein compare
MMP_RS05835 +0.5 0.4 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS04965 +0.5 2.7 thioredoxin family protein compare
MMP_RS04260 +0.5 1.9 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS01430 +0.5 1.8 mechanosensitive ion channel family protein compare
MMP_RS01210 +0.5 1.7 sodium:solute symporter compare
MMP_RS00375 +0.5 2.4 ammonium transporter compare
MMP_RS02610 +0.5 2.0 DUF2162 domain-containing protein compare
MMP_RS01650 +0.5 0.5 sulfurtransferase TusA family protein compare
MMP_RS08340 +0.5 2.0 4Fe-4S binding protein compare
MMP_RS00695 +0.5 0.3 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01685 +0.5 0.9 indolepyruvate oxidoreductase subunit beta compare
MMP_RS04055 +0.5 0.8 hypothetical protein compare
MMP_RS00705 +0.5 0.8 hypothetical protein compare
MMP_RS03800 +0.5 1.3 hypothetical protein compare
MMP_RS08380 +0.5 2.3 phosphatase PAP2 family protein compare
MMP_RS05675 +0.5 0.9 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS00450 +0.5 0.8 4Fe-4S binding protein compare
MMP_RS06440 +0.5 1.4 CBS domain-containing protein compare
MMP_RS08660 +0.5 1.6 DHH family phosphoesterase compare
MMP_RS00990 +0.5 1.1 hypothetical protein compare
MMP_RS06520 +0.5 1.2 DUF1786 domain-containing protein compare
MMP_RS00670 +0.5 1.0 TIM barrel protein compare
MMP_RS01775 +0.5 0.8 TIGR00297 family protein compare
MMP_RS08215 +0.5 0.8 DUF483 domain-containing protein compare
MMP_RS03535 +0.5 1.0 helix-turn-helix transcriptional regulator compare
MMP_RS01870 +0.5 3.0 acyl-CoA dehydratase activase compare
MMP_RS02740 +0.4 1.1 hypothetical protein compare
MMP_RS06150 +0.4 2.1 hypothetical protein compare
MMP_RS01630 +0.4 1.5 N-glycosylase/DNA lyase compare
MMP_RS00980 +0.4 2.5 hypothetical protein compare
MMP_RS05445 +0.4 1.7 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS04530 +0.4 1.2 ABC transporter permease compare
MMP_RS08700 +0.4 2.0 hypothetical protein compare
MMP_RS04035 +0.4 0.9 hypothetical protein compare
MMP_RS01240 +0.4 0.4 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS01010 +0.4 1.9 DUF4352 domain-containing protein compare
MMP_RS04960 +0.4 2.0 cytochrome c biogenesis CcdA family protein compare
MMP_RS04445 +0.4 2.3 P-II family nitrogen regulator compare
MMP_RS01895 +0.4 1.9 flippase compare
MMP_RS06050 +0.4 1.3 ZIP family metal transporter compare
MMP_RS03965 +0.4 0.8 hypothetical protein compare
MMP_RS01155 +0.4 1.5 XRE family transcriptional regulator compare
MMP_RS03340 +0.4 0.4 ABC transporter ATP-binding protein compare
MMP_RS05940 +0.4 1.2 corrinoid protein compare
MMP_RS02550 +0.4 1.4 helix-turn-helix transcriptional regulator compare
MMP_RS01835 +0.4 2.2 hypothetical protein compare
MMP_RS08600 +0.4 0.7 flagellar protein D compare
MMP_RS08605 +0.4 1.3 flagellar protein E compare
MMP_RS02905 +0.4 1.5 2-thiouracil desulfurase family protein compare
MMP_RS08335 +0.4 1.1 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS08590 +0.4 0.5 flagellin compare
MMP_RS05435 +0.4 1.8 5'/3'-nucleotidase SurE compare
MMP_RS02300 +0.4 1.2 NAD(P)H-dependent oxidoreductase compare
MMP_RS02745 +0.4 0.8 hypothetical protein compare
MMP_RS06445 +0.4 1.3 DUF89 domain-containing protein compare
MMP_RS03495 +0.4 1.1 Na/Pi cotransporter family protein compare
MMP_RS03335 +0.4 1.3 ABC transporter permease compare
MMP_RS05365 +0.4 0.7 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS06370 +0.4 1.2 biotin synthase BioB compare
MMP_RS05795 +0.3 1.1 redox-regulated ATPase YchF compare
MMP_RS05530 +0.3 1.7 signal peptide peptidase SppA compare
MMP_RS02770 +0.3 1.0 hypothetical protein compare
MMP_RS03815 +0.3 1.5 excinuclease ABC subunit UvrA compare
MMP_RS05975 +0.3 1.5 hypothetical protein compare
MMP_RS07710 +0.3 1.0 cell division protein FtsZ compare
MMP_RS02380 +0.3 1.6 ATP-binding protein compare
MMP_RS06990 +0.3 0.9 CatB-related O-acetyltransferase compare
MMP_RS06570 +0.3 0.9 DUF190 domain-containing protein compare
MMP_RS06585 +0.3 0.5 DMT family protein compare
MMP_RS00235 +0.3 1.6 HDIG domain-containing protein compare
MMP_RS01645 +0.3 1.2 SWIM zinc finger family protein compare
MMP_RS01605 +0.3 1.5 hypothetical protein compare
MMP_RS03830 +0.3 1.7 exodeoxyribonuclease VII large subunit compare
MMP_RS06305 +0.3 1.7 transporter substrate-binding domain-containing protein compare
MMP_RS08975 +0.3 0.7 hypothetical protein compare
MMP_RS03420 +0.3 0.6 acetolactate synthase small subunit compare
MMP_RS02325 +0.3 1.3 epoxyqueuosine reductase compare
MMP_RS08315 +0.3 0.6 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS02360 +0.3 1.3 hypothetical protein compare
MMP_RS05910 +0.3 0.6 cell division ATPase MinD compare
MMP_RS06550 +0.3 1.1 AMP-binding protein compare
MMP_RS03775 +0.3 0.5 4Fe-4S dicluster domain-containing protein compare
MMP_RS01850 +0.3 1.9 phosphate ABC transporter substrate-binding protein compare
MMP_RS06735 +0.3 0.9 class I SAM-dependent rRNA methyltransferase compare
MMP_RS07085 +0.3 1.9 ribonuclease HII compare
MMP_RS05955 +0.3 0.6 CoB--CoM heterodisulfide reductase subunit C compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress sodium bromide across organisms