Experiment set14S746 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Novobiocin sodium salt 0.025 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS02900 -4.8 -0.7 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS01795 -4.8 -1.6 methanogenesis marker 6 protein compare
MMP_RS06895 -4.5 -1.5 selenocysteine-specific translation elongation factor compare
MMP_RS08460 -4.4 -2.6 proteasome-activating nucleotidase compare
MMP_RS05920 -4.3 -0.6 50S ribosomal protein L37e compare
MMP_RS08720 -4.0 -1.4 4Fe-4S binding protein compare
MMP_RS08210 -3.7 -2.1 phosphatidylglycerophosphatase A compare
MMP_RS01005 -3.7 -1.0 riboflavin synthase compare
MMP_RS01175 -3.5 -2.9 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS07630 -3.5 -1.7 ATP-binding cassette domain-containing protein compare
MMP_RS01265 -3.5 -2.6 hypothetical protein compare
MMP_RS01385 -3.5 -0.7 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS03445 -3.4 -0.9 methanogenesis marker 17 protein compare
MMP_RS01380 -3.4 -4.8 PHP domain-containing protein compare
MMP_RS03600 -3.4 -2.4 triose-phosphate isomerase compare
MMP_RS00305 -3.3 -1.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS00520 -3.3 -1.5 RNA polymerase Rpb4 family protein compare
MMP_RS08715 -3.3 -1.7 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07635 -3.2 -5.7 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08300 -3.2 -1.0 metal-sulfur cluster assembly factor compare
MMP_RS06730 -3.1 -1.7 phosphopantothenate/pantothenate synthetase compare
MMP_RS04710 -3.1 -1.5 hypothetical protein compare
MMP_RS06625 -3.1 -1.8 DNA primase compare
MMP_RS04890 -3.0 -0.8 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS02175 -3.0 -0.8 DUF1611 domain-containing protein compare
MMP_RS05845 -2.9 -1.5 tRNA-intron lyase compare
MMP_RS08435 -2.9 -2.3 Era-like GTP-binding protein compare
MMP_RS04685 -2.9 -2.5 DUF126 domain-containing protein compare
MMP_RS01960 -2.9 -0.8 hypothetical protein compare
MMP_RS08635 -2.9 -2.0 UbiA family prenyltransferase compare
MMP_RS02875 -2.9 -6.4 chorismate pyruvate-lyase family protein compare
MMP_RS06295 -2.9 -5.1 methanogenesis marker 14 protein compare
MMP_RS00300 -2.9 -0.6 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06230 -2.8 -2.6 helix-turn-helix domain-containing protein compare
MMP_RS06355 -2.8 -2.0 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS03960 -2.6 -0.8 hypothetical protein compare
MMP_RS01610 -2.6 -2.6 hypothetical protein compare
MMP_RS06020 -2.6 -3.8 archaeoflavoprotein AfpA compare
MMP_RS03015 -2.6 -7.2 GTP 3' 8-cyclase MoaA compare
MMP_RS08940 -2.6 -1.4 MetS family NSS transporter small subunit compare
MMP_RS08820 -2.5 -5.0 hypothetical protein compare
MMP_RS06840 -2.5 -0.9 DNA-directed RNA polymerase subunit N compare
MMP_RS01020 -2.5 -0.8 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS05765 -2.5 -5.4 M42 family metallopeptidase compare
MMP_RS01500 -2.4 -1.5 CBS domain-containing protein compare
MMP_RS06110 -2.4 -3.3 ATP-dependent protease LonB compare
MMP_RS07730 -2.4 -1.6 pyruvate synthase subunit beta compare
MMP_RS05430 -2.4 -4.5 TIGR00288 family NYN domain-containing protein compare
MMP_RS03640 -2.3 -2.8 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01755 -2.3 -0.8 DUF2097 domain-containing protein compare
MMP_RS08650 -2.3 -2.6 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS06400 -2.3 -1.3 4Fe-4S binding protein compare
MMP_RS07390 -2.3 -2.1 cell division protein FtsZ compare
MMP_RS05515 -2.2 -5.1 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS07445 -2.2 -4.6 helix-turn-helix domain-containing protein compare
MMP_RS08790 -2.2 -2.3 translation initiation factor IF-2 subunit alpha compare
MMP_RS04585 -2.2 -7.9 AIR synthase related protein compare
MMP_RS08645 -2.2 -6.4 UPF0179 family protein compare
MMP_RS01225 -2.1 -3.9 DUF5379 domain-containing protein compare
MMP_RS00130 -2.1 -1.0 nickel-responsive transcriptional regulator NikR compare
MMP_RS07755 -2.1 -1.0 DUF555 domain-containing protein compare
MMP_RS02240 -2.1 -1.7 methanogenesis marker 7 protein compare
MMP_RS05835 -2.1 -0.7 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS06975 -2.1 -1.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS03700 -2.0 -6.5 sodium:proton antiporter compare
MMP_RS00515 -2.0 -0.9 DUF655 domain-containing protein compare
MMP_RS01325 -2.0 -1.6 dihydroneopterin aldolase family protein compare
MMP_RS07380 -2.0 -1.8 transcription elongation factor Spt5 compare
MMP_RS00695 -2.0 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06725 -1.9 -6.4 hypothetical protein compare
MMP_RS03400 -1.9 -2.1 archease compare
MMP_RS06350 -1.9 -4.5 HesA/MoeB/ThiF family protein compare
MMP_RS04780 -1.9 -2.3 ribonuclease P compare
MMP_RS01085 -1.9 -1.6 hypothetical protein compare
MMP_RS00730 -1.9 -4.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS00750 -1.9 -2.0 fumarate hydratase compare
MMP_RS07525 -1.9 -5.8 4Fe-4S binding protein compare
MMP_RS02195 -1.8 -2.2 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS05865 -1.8 -2.8 hypothetical protein compare
MMP_RS04485 -1.8 -8.4 putative beta-lysine N-acetyltransferase compare
MMP_RS06600 -1.7 -1.1 class III signal peptide-containing protein compare
MMP_RS06290 -1.7 -3.1 DNA repair and recombination protein RadA compare
MMP_RS05815 -1.7 -1.9 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS07600 -1.7 -1.4 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS05540 -1.7 -2.5 hypothetical protein compare
MMP_RS03025 -1.7 -2.9 molybdenum cofactor guanylyltransferase compare
MMP_RS08570 -1.6 -7.0 coenzyme F420-0:L-glutamate ligase compare
MMP_RS03555 -1.6 -6.3 transcriptional regulator compare
MMP_RS08195 -1.6 -6.1 hypothetical protein compare
MMP_RS05020 -1.6 -2.8 hypothetical protein compare
MMP_RS08225 -1.6 -6.2 RimK family alpha-L-glutamate ligase compare
MMP_RS06630 -1.6 -0.6 UPF0058 family protein compare
MMP_RS00685 -1.5 -2.3 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07620 -1.5 -2.7 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS01365 -1.5 -2.7 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS00725 -1.5 -5.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS00040 -1.5 -4.8 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS01280 -1.5 -10.0 DUF515 domain-containing protein compare
MMP_RS09020 -1.5 -1.1 hypothetical protein compare
MMP_RS00900 -1.4 -1.4 50S ribosomal protein L39e compare
MMP_RS01285 -1.4 -6.2 hypothetical protein compare
MMP_RS06485 -1.4 -0.7 zinc ribbon domain-containing protein compare
MMP_RS01800 -1.4 -1.6 TIGR00303 family protein compare
MMP_RS07615 -1.4 -4.6 energy-coupling factor ABC transporter permease compare
MMP_RS00320 -1.4 -1.3 class I SAM-dependent methyltransferase compare
MMP_RS05545 -1.4 -3.3 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS07625 -1.4 -1.8 cobalt ECF transporter T component CbiQ compare
MMP_RS01290 -1.4 -6.4 class III signal peptide-containing protein compare
MMP_RS03125 -1.4 -4.7 cell division ATPase MinD compare
MMP_RS05355 -1.4 -0.7 hypothetical protein compare
MMP_RS00245 -1.3 -10.4 type II secretion system F family protein compare
MMP_RS08200 -1.3 -9.0 archaeosine synthase subunit alpha compare
MMP_RS06270 -1.3 -2.6 TIGR00300 family protein compare
MMP_RS06035 -1.3 -6.3 glycosyltransferase family 2 protein compare
MMP_RS03305 -1.3 -5.0 winged helix-turn-helix domain-containing protein compare
MMP_RS06885 -1.3 -1.0 50S ribosome-binding GTPase compare
MMP_RS01270 -1.3 -7.4 prepilin peptidase compare
MMP_RS06175 -1.3 -4.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS00250 -1.3 -9.3 Flp pilus assembly complex ATPase component TadA compare
MMP_RS01310 -1.3 -9.0 hypothetical protein compare
MMP_RS01295 -1.3 -7.0 hypothetical protein compare
MMP_RS02930 -1.3 -2.4 class I SAM-dependent methyltransferase compare
MMP_RS06925 -1.3 -1.4 ribonuclease VapC4 compare
MMP_RS05285 -1.3 -4.4 MMPL family transporter compare
MMP_RS00240 -1.2 -7.4 type II secretion system F family protein compare
MMP_RS05850 -1.2 -2.7 Ldh family oxidoreductase compare
MMP_RS09055 -1.2 -0.7 CAP domain-containing protein compare
MMP_RS00895 -1.2 -1.7 hypothetical protein compare
MMP_RS03315 -1.2 -0.6 ferrous iron transport protein A compare
MMP_RS02280 -1.2 -0.6 DUF211 domain-containing protein compare
MMP_RS06340 -1.2 -4.6 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS08855 -1.2 -6.1 hypothetical protein compare
MMP_RS06200 -1.2 -4.7 M24 family metallopeptidase compare
MMP_RS07735 -1.2 -0.5 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06475 -1.2 -2.5 FAD-dependent oxidoreductase compare
MMP_RS01180 -1.2 -1.2 XTP/dITP diphosphatase compare
MMP_RS03550 -1.2 -1.2 DUF2124 domain-containing protein compare
MMP_RS00570 -1.2 -1.0 protein-L-isoaspartate O-methyltransferase compare
MMP_RS01305 -1.2 -8.4 hypothetical protein compare
MMP_RS00735 -1.2 -2.3 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS04955 -1.2 -2.5 DNA topoisomerase I compare
MMP_RS03535 -1.2 -2.1 helix-turn-helix transcriptional regulator compare
MMP_RS05245 -1.2 -5.1 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS04850 -1.2 -7.2 UPF0254 family protein compare
MMP_RS07695 -1.1 -3.0 DUF3236 domain-containing protein compare
MMP_RS06395 -1.1 -2.8 ThiF family adenylyltransferase compare
MMP_RS08100 -1.1 -3.8 8-amino-7-oxononanoate synthase compare
MMP_RS04870 -1.1 -2.6 TIGR02253 family HAD-type hydrolase compare
MMP_RS01315 -1.1 -8.3 DUF2341 domain-containing protein compare
MMP_RS03580 -1.1 -1.6 signal recognition particle-docking protein FtsY compare
MMP_RS05265 -1.1 -1.3 2-isopropylmalate synthase compare
MMP_RS03440 -1.1 -0.7 MoaD/ThiS family protein compare
MMP_RS00115 -1.1 -5.2 radical SAM protein compare
MMP_RS05500 -1.1 -3.8 2-isopropylmalate synthase compare
MMP_RS05090 -1.1 -4.0 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS08860 -1.1 -3.5 MinD/ParA family protein compare
MMP_RS06865 -1.1 -1.4 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS02235 -1.1 -4.0 CBS domain-containing protein compare
MMP_RS07330 -1.0 -7.2 membrane protein compare
MMP_RS07200 -1.0 -2.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05085 -1.0 -4.6 AAA family ATPase compare
MMP_RS01985 -1.0 -2.7 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS07425 -1.0 -2.5 GTP-binding protein compare
MMP_RS02745 -1.0 -1.4 hypothetical protein compare
MMP_RS07365 -1.0 -5.1 2-phosphoglycerate kinase compare
MMP_RS05100 -1.0 -6.9 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS03035 -1.0 -2.1 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01700 -1.0 -0.6 dihydroxy-acid dehydratase compare
MMP_RS05280 -1.0 -4.6 COG1361 S-layer family protein compare
MMP_RS08675 -1.0 -1.3 class III signal peptide-containing protein compare
MMP_RS06015 -1.0 -2.6 flavodoxin family protein compare
MMP_RS03390 -1.0 -2.6 malate dehydrogenase compare
MMP_RS05635 -1.0 -4.4 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS07710 -0.9 -3.1 cell division protein FtsZ compare
MMP_RS05295 -0.9 -4.3 minichromosome maintenance protein MCM compare
MMP_RS00315 -0.9 -2.2 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01655 -0.9 -1.9 DsrE family protein compare
MMP_RS01665 -0.9 -1.8 DUF2111 domain-containing protein compare
MMP_RS01445 -0.9 -2.4 hypothetical protein compare
MMP_RS00690 -0.9 -2.8 MBL fold metallo-hydrolase compare
MMP_RS03590 -0.9 -2.1 METTL5 family protein compare
MMP_RS00110 -0.9 -1.1 hypothetical protein compare
MMP_RS05075 -0.9 -5.4 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS08310 -0.9 -1.1 TMEM165/GDT1 family protein compare
MMP_RS06120 -0.9 -1.1 UPF0147 family protein compare
MMP_RS01955 -0.9 -1.3 hypothetical protein compare
MMP_RS07700 -0.9 -3.8 DUF1188 domain-containing protein compare
MMP_RS00295 -0.9 -0.9 gamma carbonic anhydrase family protein compare
MMP_RS08290 -0.9 -2.5 DNA-binding protein Alba compare
MMP_RS03020 -0.9 -2.8 peptidylprolyl isomerase compare
MMP_RS06605 -0.9 -3.9 DUF5814 domain-containing protein compare
MMP_RS06090 -0.9 -3.3 iron ABC transporter permease compare
MMP_RS04090 -0.9 -1.6 hypothetical protein compare
MMP_RS06095 -0.8 -3.7 ABC transporter ATP-binding protein compare
MMP_RS05060 -0.8 -4.2 AAA family ATPase compare
MMP_RS05080 -0.8 -4.2 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS00710 -0.8 -1.1 hypothetical protein compare
MMP_RS00965 -0.8 -1.5 hypothetical protein compare
MMP_RS04480 -0.8 -4.6 lysine 2 3-aminomutase compare
MMP_RS03625 -0.8 -2.3 cell wall-binding protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Novobiocin sodium salt across organisms