Experiment set14S737 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Calcium Chloride Dihydrate 166.666666666667 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS07380 -6.6 -1.8 transcription elongation factor Spt5 compare
MMP_RS06730 -6.4 -1.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS06285 -5.5 -1.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS08210 -5.0 -1.9 phosphatidylglycerophosphatase A compare
MMP_RS01005 -4.8 -0.9 riboflavin synthase compare
MMP_RS00110 -4.6 -3.0 hypothetical protein compare
MMP_RS03435 -4.5 -1.8 ketol-acid reductoisomerase compare
MMP_RS01755 -4.5 -0.8 DUF2097 domain-containing protein compare
MMP_RS07005 -4.5 -0.6 4Fe-4S binding protein compare
MMP_RS03315 -4.1 -1.3 ferrous iron transport protein A compare
MMP_RS00685 -4.1 -3.4 2-phospho-L-lactate guanylyltransferase compare
MMP_RS06625 -4.0 -1.9 DNA primase compare
MMP_RS06315 -3.8 -0.7 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS01325 -3.7 -2.0 dihydroneopterin aldolase family protein compare
MMP_RS04480 -3.6 -19.7 lysine 2 3-aminomutase compare
MMP_RS05550 -3.6 -0.6 cation:proton antiporter compare
MMP_RS03960 -3.5 -0.8 hypothetical protein compare
MMP_RS07445 -3.5 -7.3 helix-turn-helix domain-containing protein compare
MMP_RS00695 -3.5 -0.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01225 -3.4 -3.7 DUF5379 domain-containing protein compare
MMP_RS04485 -3.3 -14.0 putative beta-lysine N-acetyltransferase compare
MMP_RS02240 -3.3 -2.3 methanogenesis marker 7 protein compare
MMP_RS01800 -3.2 -3.1 TIGR00303 family protein compare
MMP_RS08645 -3.1 -6.9 UPF0179 family protein compare
MMP_RS03300 -3.1 -0.8 TOBE domain-containing protein compare
MMP_RS01980 -3.1 -12.6 trimeric intracellular cation channel family protein compare
MMP_RS06020 -3.0 -3.0 archaeoflavoprotein AfpA compare
MMP_RS06355 -3.0 -1.9 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01500 -3.0 -1.9 CBS domain-containing protein compare
MMP_RS06475 -3.0 -4.1 FAD-dependent oxidoreductase compare
MMP_RS02875 -3.0 -7.4 chorismate pyruvate-lyase family protein compare
MMP_RS00300 -2.9 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS04710 -2.9 -1.4 hypothetical protein compare
MMP_RS04685 -2.8 -2.3 DUF126 domain-containing protein compare
MMP_RS07525 -2.8 -5.8 4Fe-4S binding protein compare
MMP_RS06680 -2.8 -8.1 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06340 -2.8 -5.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07545 -2.7 -0.8 HTH domain-containing protein compare
MMP_RS07635 -2.7 -4.4 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS05525 -2.6 -5.1 calcium/sodium antiporter compare
MMP_RS03035 -2.6 -2.9 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS07765 -2.6 -9.0 sodium:alanine symporter family protein compare
MMP_RS03015 -2.6 -6.1 GTP 3' 8-cyclase MoaA compare
MMP_RS08635 -2.5 -1.7 UbiA family prenyltransferase compare
MMP_RS05635 -2.5 -6.5 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS06975 -2.5 -1.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07330 -2.5 -14.8 membrane protein compare
MMP_RS00895 -2.5 -2.5 hypothetical protein compare
MMP_RS06175 -2.4 -3.8 winged helix-turn-helix transcriptional regulator compare
MMP_RS07620 -2.4 -4.7 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS08820 -2.4 -4.8 hypothetical protein compare
MMP_RS01985 -2.4 -4.5 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS08435 -2.4 -2.0 Era-like GTP-binding protein compare
MMP_RS07425 -2.4 -4.9 GTP-binding protein compare
MMP_RS06035 -2.4 -8.2 glycosyltransferase family 2 protein compare
MMP_RS05515 -2.4 -5.0 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS01610 -2.4 -2.1 hypothetical protein compare
MMP_RS02900 -2.3 -0.6 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS04955 -2.3 -3.7 DNA topoisomerase I compare
MMP_RS08790 -2.3 -2.0 translation initiation factor IF-2 subunit alpha compare
MMP_RS05510 -2.3 -6.5 Rrf2 family transcriptional regulator compare
MMP_RS03555 -2.2 -5.7 transcriptional regulator compare
MMP_RS07750 -2.2 -6.4 DUF357 domain-containing protein compare
MMP_RS05865 -2.2 -3.2 hypothetical protein compare
MMP_RS03640 -2.2 -2.4 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS04585 -2.1 -6.4 AIR synthase related protein compare
MMP_RS06725 -2.1 -7.3 hypothetical protein compare
MMP_RS00115 -2.1 -8.5 radical SAM protein compare
MMP_RS06105 -2.0 -5.9 hydrogenase maturation peptidase HycI compare
MMP_RS06350 -2.0 -3.9 HesA/MoeB/ThiF family protein compare
MMP_RS06400 -2.0 -1.2 4Fe-4S binding protein compare
MMP_RS00520 -2.0 -1.3 RNA polymerase Rpb4 family protein compare
MMP_RS05090 -2.0 -7.2 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS00130 -2.0 -0.9 nickel-responsive transcriptional regulator NikR compare
MMP_RS06345 -2.0 -7.2 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS05430 -2.0 -3.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS00915 -2.0 -4.8 DUF116 domain-containing protein compare
MMP_RS03445 -2.0 -0.8 methanogenesis marker 17 protein compare
MMP_RS08715 -2.0 -1.2 formylmethanofuran dehydrogenase subunit B compare
MMP_RS00725 -2.0 -5.8 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS07605 -1.9 -2.8 diadenylate cyclase compare
MMP_RS02195 -1.9 -2.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS06885 -1.9 -1.7 50S ribosome-binding GTPase compare
MMP_RS03025 -1.9 -3.2 molybdenum cofactor guanylyltransferase compare
MMP_RS02245 -1.9 -2.8 hypothetical protein compare
MMP_RS02165 -1.9 -5.0 tRNA-dihydrouridine synthase compare
MMP_RS05100 -1.9 -11.5 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS00620 -1.9 -6.5 4Fe-4S binding protein compare
MMP_RS04890 -1.9 -0.6 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS00315 -1.9 -4.6 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS06940 -1.9 -3.0 polyprenyl diphosphate synthase compare
MMP_RS05640 -1.9 -4.4 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS03400 -1.8 -1.5 archease compare
MMP_RS01840 -1.8 -6.8 TIGR00289 family protein compare
MMP_RS01700 -1.8 -0.8 dihydroxy-acid dehydratase compare
MMP_RS06120 -1.8 -1.3 UPF0147 family protein compare
MMP_RS00735 -1.8 -4.3 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS06200 -1.8 -6.5 M24 family metallopeptidase compare
MMP_RS06685 -1.8 -6.8 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS01960 -1.7 -0.6 hypothetical protein compare
MMP_RS06290 -1.7 -3.3 DNA repair and recombination protein RadA compare
MMP_RS03305 -1.7 -6.4 winged helix-turn-helix domain-containing protein compare
MMP_RS01380 -1.7 -3.1 PHP domain-containing protein compare
MMP_RS05095 -1.7 -4.7 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS07700 -1.6 -6.4 DUF1188 domain-containing protein compare
MMP_RS00810 -1.6 -6.0 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS00290 -1.6 -4.1 hypothetical protein compare
MMP_RS01795 -1.6 -0.9 methanogenesis marker 6 protein compare
MMP_RS07685 -1.6 -4.5 TIGR01212 family radical SAM protein compare
MMP_RS08745 -1.6 -3.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS05545 -1.6 -4.2 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS00295 -1.6 -1.5 gamma carbonic anhydrase family protein compare
MMP_RS07775 -1.6 -4.7 alanine dehydrogenase compare
MMP_RS06930 -1.5 -6.1 MBL fold metallo-hydrolase compare
MMP_RS05765 -1.5 -3.6 M42 family metallopeptidase compare
MMP_RS06855 -1.5 -6.7 hypothetical protein compare
MMP_RS01335 -1.5 -1.7 prefoldin subunit beta compare
MMP_RS02605 -1.5 -0.7 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS01020 -1.5 -0.6 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS00555 -1.5 -5.0 MFS transporter compare
MMP_RS05075 -1.5 -8.9 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS05250 -1.5 -2.7 NFYB/HAP3 family transcription factor subunit compare
MMP_RS06630 -1.5 -0.5 UPF0058 family protein compare
MMP_RS07625 -1.5 -2.3 cobalt ECF transporter T component CbiQ compare
MMP_RS05245 -1.5 -5.3 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS06670 -1.5 -2.8 glucose-6-phosphate isomerase compare
MMP_RS01885 -1.5 -3.5 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS06270 -1.4 -2.9 TIGR00300 family protein compare
MMP_RS00305 -1.4 -1.3 phosphoribosyl-ATP diphosphatase compare
MMP_RS05920 -1.4 -0.4 50S ribosomal protein L37e compare
MMP_RS04790 -1.4 -7.2 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS00945 -1.4 -0.9 PadR family transcriptional regulator compare
MMP_RS05080 -1.4 -4.8 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS05295 -1.3 -6.0 minichromosome maintenance protein MCM compare
MMP_RS05125 -1.3 -6.7 D-aminoacyl-tRNA deacylase compare
MMP_RS05085 -1.3 -5.3 AAA family ATPase compare
MMP_RS01655 -1.3 -2.6 DsrE family protein compare
MMP_RS05555 -1.3 -0.9 DUF4040 domain-containing protein compare
MMP_RS07580 -1.3 -1.6 DUF356 domain-containing protein compare
MMP_RS01875 -1.3 -3.8 N-acetyltransferase compare
MMP_RS02175 -1.3 -0.5 DUF1611 domain-containing protein compare
MMP_RS00050 -1.3 -3.5 AarF/UbiB family protein compare
MMP_RS06015 -1.3 -3.3 flavodoxin family protein compare
MMP_RS05580 -1.3 -6.7 glycosyltransferase compare
MMP_RS05020 -1.3 -2.3 hypothetical protein compare
MMP_RS00730 -1.3 -2.8 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS03550 -1.3 -1.0 DUF2124 domain-containing protein compare
MMP_RS01175 -1.3 -1.6 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03095 -1.2 -3.8 diphthine synthase compare
MMP_RS07630 -1.2 -0.9 ATP-binding cassette domain-containing protein compare
MMP_RS06840 -1.2 -0.6 DNA-directed RNA polymerase subunit N compare
MMP_RS06230 -1.2 -1.3 helix-turn-helix domain-containing protein compare
MMP_RS04990 -1.2 -4.3 aquaporin family protein compare
MMP_RS00320 -1.2 -1.1 class I SAM-dependent methyltransferase compare
MMP_RS06395 -1.2 -2.8 ThiF family adenylyltransferase compare
MMP_RS01445 -1.2 -3.4 hypothetical protein compare
MMP_RS04850 -1.2 -8.2 UPF0254 family protein compare
MMP_RS02010 -1.2 -3.9 PHP domain-containing protein compare
MMP_RS05845 -1.2 -0.9 tRNA-intron lyase compare
MMP_RS07615 -1.2 -2.9 energy-coupling factor ABC transporter permease compare
MMP_RS08460 -1.2 -1.4 proteasome-activating nucleotidase compare
MMP_RS08165 -1.2 -1.1 phosphoglycerate dehydrogenase compare
MMP_RS06295 -1.2 -2.8 methanogenesis marker 14 protein compare
MMP_RS05060 -1.2 -5.3 AAA family ATPase compare
MMP_RS05540 -1.2 -1.6 hypothetical protein compare
MMP_RS08105 -1.2 -4.1 6-carboxyhexanoate--CoA ligase compare
MMP_RS05055 -1.1 -6.4 DUF166 domain-containing protein compare
MMP_RS04090 -1.1 -1.3 hypothetical protein compare
MMP_RS01720 -1.1 -0.9 replication factor C large subunit compare
MMP_RS00310 -1.1 -5.5 CBS domain-containing protein compare
MMP_RS01250 -1.1 -5.0 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS07600 -1.1 -1.0 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS07845 -1.1 -0.9 LL-diaminopimelate aminotransferase compare
MMP_RS07200 -1.1 -2.2 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS01495 -1.1 -4.8 TraB/GumN family protein compare
MMP_RS08300 -1.1 -0.6 metal-sulfur cluster assembly factor compare
MMP_RS06865 -1.1 -1.4 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS08615 -1.1 -1.0 flagellar protein G compare
MMP_RS00040 -1.1 -3.3 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS02410 -1.1 -1.6 ABC transporter substrate-binding protein compare
MMP_RS01665 -1.1 -2.2 DUF2111 domain-containing protein compare
MMP_RS01890 -1.1 -2.0 nucleotide sugar dehydrogenase compare
MMP_RS06525 -1.1 -0.7 YciI family protein compare
MMP_RS08225 -1.1 -4.3 RimK family alpha-L-glutamate ligase compare
MMP_RS07535 -1.1 -4.3 4Fe-4S binding protein compare
MMP_RS07770 -1.0 -3.0 alanine racemase compare
MMP_RS08570 -1.0 -4.3 coenzyme F420-0:L-glutamate ligase compare
MMP_RS05815 -1.0 -1.2 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS04500 -1.0 -6.7 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS02935 -1.0 -1.9 A24 family peptidase compare
MMP_RS05265 -1.0 -1.0 2-isopropylmalate synthase compare
MMP_RS03560 -1.0 -6.2 Na+/H+ antiporter NhaC family protein compare
MMP_RS03600 -1.0 -0.8 triose-phosphate isomerase compare
MMP_RS02345 -1.0 -1.7 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS05535 -1.0 -2.4 hypothetical protein compare
MMP_RS02545 -1.0 -2.5 hypothetical protein compare
MMP_RS08200 -1.0 -6.2 archaeosine synthase subunit alpha compare
MMP_RS03700 -0.9 -2.9 sodium:proton antiporter compare
MMP_RS05070 -0.9 -2.7 4Fe-4S dicluster domain-containing protein compare
MMP_RS07350 -0.9 -0.9 preprotein translocase subunit Sec61beta compare


Specific Phenotypes

For 1 genes in this experiment

For stress Calcium chloride dihydrate in Methanococcus maripaludis S2

For stress Calcium chloride dihydrate across organisms