Experiment set14S724 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Rifampicin 0.5 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS01365 -7.5 -2.2 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS01175 -6.8 -1.8 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS02875 -6.4 -6.9 chorismate pyruvate-lyase family protein compare
MMP_RS01380 -6.3 -2.8 PHP domain-containing protein compare
MMP_RS06020 -6.2 -3.1 archaeoflavoprotein AfpA compare
MMP_RS03600 -6.2 -1.5 triose-phosphate isomerase compare
MMP_RS03445 -6.1 -0.7 methanogenesis marker 17 protein compare
MMP_RS06730 -6.0 -1.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS04090 -5.9 -2.3 hypothetical protein compare
MMP_RS06400 -5.9 -1.1 4Fe-4S binding protein compare
MMP_RS07605 -5.9 -2.4 diadenylate cyclase compare
MMP_RS06840 -5.8 -0.6 DNA-directed RNA polymerase subunit N compare
MMP_RS04685 -5.7 -2.2 DUF126 domain-containing protein compare
MMP_RS01225 -5.7 -3.8 DUF5379 domain-containing protein compare
MMP_RS03960 -5.7 -0.6 hypothetical protein compare
MMP_RS03580 -5.6 -2.7 signal recognition particle-docking protein FtsY compare
MMP_RS00305 -5.5 -1.3 phosphoribosyl-ATP diphosphatase compare
MMP_RS04775 -5.5 -2.5 adenosylhomocysteinase compare
MMP_RS06230 -5.5 -1.6 helix-turn-helix domain-containing protein compare
MMP_RS05280 -5.4 -10.0 COG1361 S-layer family protein compare
MMP_RS01955 -5.3 -2.1 hypothetical protein compare
MMP_RS06110 -5.2 -2.8 ATP-dependent protease LonB compare
MMP_RS08790 -5.2 -1.5 translation initiation factor IF-2 subunit alpha compare
MMP_RS06700 -5.1 -9.8 hypothetical protein compare
MMP_RS05285 -5.1 -6.8 MMPL family transporter compare
MMP_RS04780 -5.0 -2.1 ribonuclease P compare
MMP_RS08745 -5.0 -4.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS00685 -5.0 -2.9 2-phospho-L-lactate guanylyltransferase compare
MMP_RS03315 -5.0 -0.9 ferrous iron transport protein A compare
MMP_RS07635 -4.9 -5.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS04585 -4.9 -11.2 AIR synthase related protein compare
MMP_RS01495 -4.9 -9.8 TraB/GumN family protein compare
MMP_RS06600 -4.9 -0.7 class III signal peptide-containing protein compare
MMP_RS06295 -4.9 -5.0 methanogenesis marker 14 protein compare
MMP_RS02900 -4.8 -0.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS05550 -4.8 -0.5 cation:proton antiporter compare
MMP_RS01500 -4.8 -1.5 CBS domain-containing protein compare
MMP_RS03700 -4.8 -8.8 sodium:proton antiporter compare
MMP_RS01005 -4.8 -0.7 riboflavin synthase compare
MMP_RS07730 -4.7 -1.1 pyruvate synthase subunit beta compare
MMP_RS03025 -4.7 -4.9 molybdenum cofactor guanylyltransferase compare
MMP_RS07075 -4.6 -3.1 phosphomannomutase/phosphoglucomutase compare
MMP_RS05290 -4.6 -10.4 TetR/AcrR family transcriptional regulator compare
MMP_RS09055 -4.6 -0.7 CAP domain-containing protein compare
MMP_RS03110 -4.6 -6.1 glycosyltransferase family 2 protein compare
MMP_RS00895 -4.6 -2.7 hypothetical protein compare
MMP_RS04710 -4.5 -1.4 hypothetical protein compare
MMP_RS08720 -4.5 -1.0 4Fe-4S binding protein compare
MMP_RS01610 -4.5 -2.1 hypothetical protein compare
MMP_RS03305 -4.5 -6.4 winged helix-turn-helix domain-containing protein compare
MMP_RS08460 -4.5 -2.0 proteasome-activating nucleotidase compare
MMP_RS00130 -4.4 -0.8 nickel-responsive transcriptional regulator NikR compare
MMP_RS01755 -4.4 -0.7 DUF2097 domain-containing protein compare
MMP_RS00300 -4.3 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS00320 -4.3 -1.1 class I SAM-dependent methyltransferase compare
MMP_RS07380 -4.3 -2.0 transcription elongation factor Spt5 compare
MMP_RS08600 -4.3 -1.9 flagellar protein D compare
MMP_RS02240 -4.3 -2.2 methanogenesis marker 7 protein compare
MMP_RS06175 -4.2 -3.7 winged helix-turn-helix transcriptional regulator compare
MMP_RS06285 -4.2 -1.5 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS05920 -4.2 -0.4 50S ribosomal protein L37e compare
MMP_RS01925 -4.1 -10.3 DUF1616 domain-containing protein compare
MMP_RS08435 -4.1 -1.7 Era-like GTP-binding protein compare
MMP_RS03640 -4.1 -3.0 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS05635 -4.0 -7.3 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS08650 -4.0 -2.6 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS07545 -4.0 -0.6 HTH domain-containing protein compare
MMP_RS02165 -3.9 -6.9 tRNA-dihydrouridine synthase compare
MMP_RS08840 -3.9 -10.4 class I SAM-dependent methyltransferase compare
MMP_RS04890 -3.9 -0.6 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS00725 -3.9 -8.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS06625 -3.9 -1.4 DNA primase compare
MMP_RS01975 -3.8 -13.9 hypothetical protein compare
MMP_RS08605 -3.8 -4.1 flagellar protein E compare
MMP_RS02145 -3.8 -8.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS00735 -3.8 -4.1 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS01960 -3.7 -0.6 hypothetical protein compare
MMP_RS08635 -3.7 -1.5 UbiA family prenyltransferase compare
MMP_RS06035 -3.6 -9.6 glycosyltransferase family 2 protein compare
MMP_RS01900 -3.6 -14.0 hypothetical protein compare
MMP_RS00915 -3.6 -5.9 DUF116 domain-containing protein compare
MMP_RS01020 -3.6 -0.7 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS00315 -3.6 -7.9 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS07755 -3.6 -0.8 DUF555 domain-containing protein compare
MMP_RS05640 -3.5 -6.5 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS07615 -3.5 -5.5 energy-coupling factor ABC transporter permease compare
MMP_RS06725 -3.5 -8.9 hypothetical protein compare
MMP_RS03035 -3.5 -3.5 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS03435 -3.5 -1.6 ketol-acid reductoisomerase compare
MMP_RS05930 -3.5 -1.7 3-isopropylmalate dehydratase large subunit compare
MMP_RS08820 -3.5 -3.8 hypothetical protein compare
MMP_RS00730 -3.4 -4.8 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS01385 -3.4 -0.5 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS04850 -3.4 -15.6 UPF0254 family protein compare
MMP_RS07330 -3.4 -14.6 membrane protein compare
MMP_RS03535 -3.4 -1.7 helix-turn-helix transcriptional regulator compare
MMP_RS07695 -3.3 -6.0 DUF3236 domain-containing protein compare
MMP_RS07525 -3.3 -6.2 4Fe-4S binding protein compare
MMP_RS00115 -3.3 -11.7 radical SAM protein compare
MMP_RS07200 -3.3 -5.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05580 -3.3 -12.4 glycosyltransferase compare
MMP_RS06105 -3.3 -6.9 hydrogenase maturation peptidase HycI compare
MMP_RS07390 -3.3 -2.0 cell division protein FtsZ compare
MMP_RS07820 -3.3 -3.9 UPF0104 family protein compare
MMP_RS06670 -3.2 -4.0 glucose-6-phosphate isomerase compare
MMP_RS08300 -3.2 -0.8 metal-sulfur cluster assembly factor compare
MMP_RS08715 -3.2 -1.3 formylmethanofuran dehydrogenase subunit B compare
MMP_RS09020 -3.2 -1.1 hypothetical protein compare
MMP_RS06630 -3.2 -0.5 UPF0058 family protein compare
MMP_RS05345 -3.1 -5.4 hypothetical protein compare
MMP_RS06120 -3.1 -1.6 UPF0147 family protein compare
MMP_RS06680 -3.1 -6.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS08590 -3.1 -4.0 flagellin compare
MMP_RS01220 -3.1 -4.7 hypothetical protein compare
MMP_RS06395 -3.1 -2.9 ThiF family adenylyltransferase compare
MMP_RS01800 -3.1 -2.5 TIGR00303 family protein compare
MMP_RS08645 -3.1 -4.8 UPF0179 family protein compare
MMP_RS06870 -3.0 -4.4 DedA family protein compare
MMP_RS01865 -3.0 -1.1 GPR1/FUN34/YaaH family transporter compare
MMP_RS01970 -3.0 -10.8 TIGR04279 domain-containing protein compare
MMP_RS03555 -3.0 -6.9 transcriptional regulator compare
MMP_RS06895 -2.9 -1.0 selenocysteine-specific translation elongation factor compare
MMP_RS01885 -2.9 -5.7 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01875 -2.9 -6.0 N-acetyltransferase compare
MMP_RS05430 -2.9 -2.9 TIGR00288 family NYN domain-containing protein compare
MMP_RS02470 -2.8 -1.2 helix-turn-helix transcriptional regulator compare
MMP_RS07445 -2.8 -5.0 helix-turn-helix domain-containing protein compare
MMP_RS08195 -2.8 -8.4 hypothetical protein compare
MMP_RS07700 -2.8 -6.1 DUF1188 domain-containing protein compare
MMP_RS01725 -2.8 -2.5 class I SAM-dependent methyltransferase family protein compare
MMP_RS01325 -2.8 -1.5 dihydroneopterin aldolase family protein compare
MMP_RS06975 -2.8 -1.3 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07600 -2.8 -1.6 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS08440 -2.7 -2.3 cell division protein SepF compare
MMP_RS07580 -2.7 -2.2 DUF356 domain-containing protein compare
MMP_RS07630 -2.7 -1.2 ATP-binding cassette domain-containing protein compare
MMP_RS04870 -2.7 -3.1 TIGR02253 family HAD-type hydrolase compare
MMP_RS01880 -2.7 -3.8 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS05265 -2.7 -1.5 2-isopropylmalate synthase compare
MMP_RS07625 -2.7 -2.2 cobalt ECF transporter T component CbiQ compare
MMP_RS03205 -2.6 -1.1 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS02195 -2.6 -2.4 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07845 -2.6 -1.1 LL-diaminopimelate aminotransferase compare
MMP_RS07710 -2.6 -5.9 cell division protein FtsZ compare
MMP_RS07425 -2.6 -4.5 GTP-binding protein compare
MMP_RS07620 -2.6 -2.7 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS06885 -2.6 -1.6 50S ribosome-binding GTPase compare
MMP_RS06270 -2.5 -3.9 TIGR00300 family protein compare
MMP_RS04720 -2.5 -1.9 DedA family protein compare
MMP_RS06685 -2.5 -7.1 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06370 -2.5 -3.3 biotin synthase BioB compare
MMP_RS07875 -2.5 -4.5 hypothetical protein compare
MMP_RS06475 -2.5 -3.5 FAD-dependent oxidoreductase compare
MMP_RS05765 -2.5 -3.5 M42 family metallopeptidase compare
MMP_RS08785 -2.4 -0.6 RNA-protein complex protein Nop10 compare
MMP_RS06340 -2.4 -5.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00985 -2.4 -3.3 CDC48 family AAA ATPase compare
MMP_RS00110 -2.4 -1.8 hypothetical protein compare
MMP_RS04955 -2.4 -4.8 DNA topoisomerase I compare
MMP_RS01990 -2.4 -2.9 hypothetical protein compare
MMP_RS00515 -2.4 -0.7 DUF655 domain-containing protein compare
MMP_RS06015 -2.4 -5.0 flavodoxin family protein compare
MMP_RS03385 -2.3 -0.8 cation diffusion facilitator family transporter compare
MMP_RS01265 -2.3 -1.5 hypothetical protein compare
MMP_RS03400 -2.3 -1.6 archease compare
MMP_RS07420 -2.3 -2.7 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS03585 -2.2 -2.7 Hsp20/alpha crystallin family protein compare
MMP_RS05355 -2.2 -0.7 hypothetical protein compare
MMP_RS01795 -2.2 -0.8 methanogenesis marker 6 protein compare
MMP_RS05845 -2.2 -1.1 tRNA-intron lyase compare
MMP_RS05295 -2.2 -7.5 minichromosome maintenance protein MCM compare
MMP_RS06375 -2.1 -3.1 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS06925 -2.1 -1.2 ribonuclease VapC4 compare
MMP_RS07900 -2.1 -1.9 YeeE/YedE family protein compare
MMP_RS06315 -2.1 -0.5 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS07355 -2.1 -0.6 transcription factor S compare
MMP_RS08095 -2.1 -5.1 dethiobiotin synthase compare
MMP_RS05815 -2.0 -1.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS06290 -2.0 -3.1 DNA repair and recombination protein RadA compare
MMP_RS01950 -2.0 -6.1 hypothetical protein compare
MMP_RS06345 -2.0 -6.3 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS03095 -2.0 -4.6 diphthine synthase compare
MMP_RS06770 -2.0 -7.1 DHH family phosphoesterase compare
MMP_RS08165 -2.0 -1.7 phosphoglycerate dehydrogenase compare
MMP_RS01930 -2.0 -7.3 hypothetical protein compare
MMP_RS03390 -1.9 -3.7 malate dehydrogenase compare
MMP_RS01455 -1.9 -4.2 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS01335 -1.9 -1.7 prefoldin subunit beta compare
MMP_RS02190 -1.9 -2.3 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS01940 -1.9 -3.0 MoxR family ATPase compare
MMP_RS06930 -1.9 -6.3 MBL fold metallo-hydrolase compare
MMP_RS02800 -1.9 -2.8 nucleotidyltransferase domain-containing protein compare
MMP_RS00695 -1.9 -0.5 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06940 -1.9 -2.2 polyprenyl diphosphate synthase compare
MMP_RS08200 -1.9 -9.7 archaeosine synthase subunit alpha compare
MMP_RS04500 -1.9 -9.8 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS02280 -1.8 -0.5 DUF211 domain-containing protein compare
MMP_RS01890 -1.8 -2.0 nucleotide sugar dehydrogenase compare
MMP_RS05245 -1.8 -6.9 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS08615 -1.8 -1.2 flagellar protein G compare


Specific Phenotypes

For 2 genes in this experiment

For stress Rifampicin in Methanococcus maripaludis S2

For stress Rifampicin across organisms