Experiment set14S717 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete dimetridazole 0.00416666666666667 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS07555 -4.5 -0.5 monovalent cation/H+ antiporter subunit E compare
MMP_RS00305 -4.0 -1.0 phosphoribosyl-ATP diphosphatase compare
MMP_RS07005 -3.5 -0.4 4Fe-4S binding protein compare
MMP_RS01020 -3.5 -0.6 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01325 -3.1 -1.3 dihydroneopterin aldolase family protein compare
MMP_RS03435 -2.9 -1.2 ketol-acid reductoisomerase compare
MMP_RS01755 -2.7 -0.6 DUF2097 domain-containing protein compare
MMP_RS03640 -2.7 -2.4 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS03315 -2.6 -0.7 ferrous iron transport protein A compare
MMP_RS05845 -2.6 -1.0 tRNA-intron lyase compare
MMP_RS07845 -2.6 -1.0 LL-diaminopimelate aminotransferase compare
MMP_RS03960 -2.6 -0.5 hypothetical protein compare
MMP_RS01005 -2.5 -0.7 riboflavin synthase compare
MMP_RS03600 -2.5 -1.3 triose-phosphate isomerase compare
MMP_RS05265 -2.4 -1.5 2-isopropylmalate synthase compare
MMP_RS03205 -2.4 -0.8 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS06730 -2.3 -1.0 phosphopantothenate/pantothenate synthetase compare
MMP_RS04090 -2.3 -1.9 hypothetical protein compare
MMP_RS01655 -2.2 -1.9 DsrE family protein compare
MMP_RS03445 -2.2 -0.5 methanogenesis marker 17 protein compare
MMP_RS07380 -2.1 -1.3 transcription elongation factor Spt5 compare
MMP_RS09020 -2.1 -0.8 hypothetical protein compare
MMP_RS04890 -2.0 -0.5 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS00300 -2.0 -0.3 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS03035 -2.0 -2.3 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS08460 -2.0 -1.5 proteasome-activating nucleotidase compare
MMP_RS01385 -1.9 -0.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS05550 -1.9 -0.4 cation:proton antiporter compare
MMP_RS07775 -1.9 -3.9 alanine dehydrogenase compare
MMP_RS06315 -1.9 -0.4 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08435 -1.9 -1.2 Era-like GTP-binding protein compare
MMP_RS00685 -1.9 -2.1 2-phospho-L-lactate guanylyltransferase compare
MMP_RS05430 -1.9 -5.1 TIGR00288 family NYN domain-containing protein compare
MMP_RS01610 -1.8 -1.5 hypothetical protein compare
MMP_RS06230 -1.8 -1.2 helix-turn-helix domain-containing protein compare
MMP_RS02900 -1.8 -0.3 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS01700 -1.8 -0.5 dihydroxy-acid dehydratase compare
MMP_RS08645 -1.8 -4.4 UPF0179 family protein compare
MMP_RS00515 -1.8 -0.6 DUF655 domain-containing protein compare
MMP_RS08605 -1.7 -3.8 flagellar protein E compare
MMP_RS06270 -1.7 -3.2 TIGR00300 family protein compare
MMP_RS08635 -1.7 -0.9 UbiA family prenyltransferase compare
MMP_RS01265 -1.6 -1.4 hypothetical protein compare
MMP_RS07525 -1.6 -5.3 4Fe-4S binding protein compare
MMP_RS01380 -1.6 -2.4 PHP domain-containing protein compare
MMP_RS08745 -1.6 -3.6 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS01545 -1.6 -0.5 CBS domain-containing protein compare
MMP_RS00040 -1.6 -4.1 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS04685 -1.6 -1.4 DUF126 domain-containing protein compare
MMP_RS01335 -1.6 -1.1 prefoldin subunit beta compare
MMP_RS05865 -1.6 -1.8 hypothetical protein compare
MMP_RS08210 -1.6 -1.0 phosphatidylglycerophosphatase A compare
MMP_RS07635 -1.6 -4.2 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS00130 -1.6 -0.6 nickel-responsive transcriptional regulator NikR compare
MMP_RS00900 -1.6 -0.9 50S ribosomal protein L39e compare
MMP_RS03305 -1.6 -4.0 winged helix-turn-helix domain-containing protein compare
MMP_RS03400 -1.5 -1.2 archease compare
MMP_RS02240 -1.5 -1.3 methanogenesis marker 7 protein compare
MMP_RS03580 -1.5 -1.7 signal recognition particle-docking protein FtsY compare
MMP_RS05515 -1.5 -3.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS00110 -1.5 -1.4 hypothetical protein compare
MMP_RS07605 -1.5 -1.6 diadenylate cyclase compare
MMP_RS00895 -1.5 -1.6 hypothetical protein compare
MMP_RS05095 -1.5 -4.6 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS04780 -1.5 -1.5 ribonuclease P compare
MMP_RS06175 -1.4 -3.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS05765 -1.4 -2.9 M42 family metallopeptidase compare
MMP_RS02345 -1.4 -1.3 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06400 -1.4 -0.6 4Fe-4S binding protein compare
MMP_RS01440 -1.4 -2.9 NAAT family transporter compare
MMP_RS03555 -1.4 -2.9 transcriptional regulator compare
MMP_RS02875 -1.4 -5.1 chorismate pyruvate-lyase family protein compare
MMP_RS05020 -1.4 -2.3 hypothetical protein compare
MMP_RS07575 -1.4 -2.0 RNA ligase partner protein compare
MMP_RS01500 -1.4 -0.8 CBS domain-containing protein compare
MMP_RS08940 -1.3 -0.6 MetS family NSS transporter small subunit compare
MMP_RS01225 -1.3 -2.3 DUF5379 domain-containing protein compare
MMP_RS04615 -1.3 -1.6 PDGLE domain-containing protein compare
MMP_RS00295 -1.3 -0.9 gamma carbonic anhydrase family protein compare
MMP_RS08725 -1.2 -0.9 Ni/Fe hydrogenase subunit alpha compare
MMP_RS07365 -1.2 -5.9 2-phosphoglycerate kinase compare
MMP_RS08590 -1.2 -2.3 flagellin compare
MMP_RS06900 -1.2 -1.4 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS02110 -1.2 -1.0 hypothetical protein compare
MMP_RS02355 -1.2 -0.9 30S ribosomal protein S27ae compare
MMP_RS09055 -1.2 -0.4 CAP domain-containing protein compare
MMP_RS00290 -1.2 -3.5 hypothetical protein compare
MMP_RS08595 -1.2 -0.6 flagellar protein C compare
MMP_RS01985 -1.2 -1.4 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS01800 -1.2 -1.5 TIGR00303 family protein compare
MMP_RS02235 -1.2 -4.1 CBS domain-containing protein compare
MMP_RS06200 -1.2 -3.1 M24 family metallopeptidase compare
MMP_RS07425 -1.1 -2.3 GTP-binding protein compare
MMP_RS08300 -1.1 -0.4 metal-sulfur cluster assembly factor compare
MMP_RS02340 -1.1 -1.0 DNA-directed RNA polymerase subunit E'' compare
MMP_RS06110 -1.1 -1.7 ATP-dependent protease LonB compare
MMP_RS02545 -1.1 -2.5 hypothetical protein compare
MMP_RS06285 -1.1 -0.7 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07615 -1.1 -2.5 energy-coupling factor ABC transporter permease compare
MMP_RS07445 -1.1 -2.5 helix-turn-helix domain-containing protein compare
MMP_RS02170 -1.1 -2.4 CBS domain-containing protein compare
MMP_RS03800 -1.1 -2.0 hypothetical protein compare
MMP_RS05930 -1.1 -0.9 3-isopropylmalate dehydratase large subunit compare
MMP_RS07730 -1.1 -0.6 pyruvate synthase subunit beta compare
MMP_RS00695 -1.0 -0.3 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01830 -1.0 -0.6 tRNA-Val compare
MMP_RS02165 -1.0 -2.7 tRNA-dihydrouridine synthase compare
MMP_RS08790 -1.0 -0.9 translation initiation factor IF-2 subunit alpha compare
MMP_RS01250 -1.0 -3.0 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS07625 -1.0 -1.3 cobalt ECF transporter T component CbiQ compare
MMP_RS08225 -1.0 -4.2 RimK family alpha-L-glutamate ligase compare
MMP_RS04870 -1.0 -2.1 TIGR02253 family HAD-type hydrolase compare
MMP_RS06035 -1.0 -4.2 glycosyltransferase family 2 protein compare
MMP_RS05420 -1.0 -2.5 DUF61 family protein compare
MMP_RS05100 -1.0 -6.7 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS05060 -1.0 -4.0 AAA family ATPase compare
MMP_RS05090 -1.0 -3.5 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS00620 -1.0 -3.0 4Fe-4S binding protein compare
MMP_RS06090 -1.0 -2.8 iron ABC transporter permease compare
MMP_RS06120 -1.0 -0.8 UPF0147 family protein compare
MMP_RS01465 -1.0 -1.1 hypothetical protein compare
MMP_RS00335 -0.9 -2.0 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS03025 -0.9 -1.9 molybdenum cofactor guanylyltransferase compare
MMP_RS08570 -0.9 -4.5 coenzyme F420-0:L-glutamate ligase compare
MMP_RS08840 -0.9 -2.9 class I SAM-dependent methyltransferase compare
MMP_RS08995 -0.9 -0.5 hypothetical protein compare
MMP_RS01110 -0.9 -1.5 FmdE family protein compare
MMP_RS03490 -0.9 -0.6 DUF2115 domain-containing protein compare
MMP_RS05500 -0.9 -2.2 2-isopropylmalate synthase compare
MMP_RS07345 -0.9 -1.8 glycine synthesis protein GlyXL (from data) compare
MMP_RS05085 -0.9 -4.7 AAA family ATPase compare
MMP_RS08400 -0.9 -1.5 MJ0307 family thioredoxin compare
MMP_RS02635 -0.9 -3.7 class I SAM-dependent methyltransferase compare
MMP_RS07755 -0.9 -0.4 DUF555 domain-containing protein compare
MMP_RS08370 -0.9 -0.2 cation:proton antiporter subunit C compare
MMP_RS01175 -0.9 -0.9 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08600 -0.8 -0.9 flagellar protein D compare
MMP_RS08200 -0.8 -5.8 archaeosine synthase subunit alpha compare
MMP_RS06020 -0.8 -1.6 archaeoflavoprotein AfpA compare
MMP_RS05075 -0.8 -4.3 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS08165 -0.8 -0.8 phosphoglycerate dehydrogenase compare
MMP_RS07200 -0.8 -2.5 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS00395 -0.8 -0.6 MGMT family protein compare
MMP_RS02905 -0.8 -1.6 2-thiouracil desulfurase family protein compare
MMP_RS03145 -0.8 -2.3 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS08720 -0.8 -0.4 4Fe-4S binding protein compare
MMP_RS08195 -0.8 -3.6 hypothetical protein compare
MMP_RS00705 -0.8 -0.8 hypothetical protein compare
MMP_RS05440 -0.8 -3.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS08555 -0.8 -1.4 hypothetical protein compare
MMP_RS01720 -0.8 -0.8 replication factor C large subunit compare
MMP_RS04220 -0.8 -3.0 queuosine precursor transporter compare
MMP_RS05920 -0.8 -0.2 50S ribosomal protein L37e compare
MMP_RS01290 -0.8 -3.2 class III signal peptide-containing protein compare
MMP_RS06625 -0.8 -0.5 DNA primase compare
MMP_RS02245 -0.8 -1.0 hypothetical protein compare
MMP_RS06975 -0.7 -0.7 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS01635 -0.7 -2.8 thiamine pyrophosphate-dependent enzyme compare
MMP_RS02540 -0.7 -2.2 DUF2283 domain-containing protein compare
MMP_RS04060 -0.7 -2.3 hypothetical protein compare
MMP_RS01085 -0.7 -0.6 hypothetical protein compare
MMP_RS06735 -0.7 -2.4 class I SAM-dependent rRNA methyltransferase compare
MMP_RS07545 -0.7 -0.3 HTH domain-containing protein compare
MMP_RS03060 -0.7 -2.5 MBL fold metallo-hydrolase compare
MMP_RS05490 -0.7 -2.4 IMPACT family protein compare
MMP_RS05635 -0.7 -1.4 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS03470 -0.7 -3.7 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS04980 -0.7 -4.0 DUF2193 domain-containing protein compare
MMP_RS02415 -0.7 -0.8 site-specific integrase compare
MMP_RS02650 -0.7 -2.2 flavodoxin family protein compare
MMP_RS07190 -0.7 -2.5 chromosome segregation protein SMC compare
MMP_RS02175 -0.7 -0.2 DUF1611 domain-containing protein compare
MMP_RS08280 -0.7 -0.9 proteasome assembly chaperone family protein compare
MMP_RS06350 -0.7 -1.7 HesA/MoeB/ThiF family protein compare
MMP_RS07535 -0.7 -3.3 4Fe-4S binding protein compare
MMP_RS02280 -0.7 -0.2 DUF211 domain-containing protein compare
MMP_RS07630 -0.7 -0.4 ATP-binding cassette domain-containing protein compare
MMP_RS06630 -0.7 -0.2 UPF0058 family protein compare
MMP_RS01330 -0.7 -4.2 DHH family phosphoesterase compare
MMP_RS00985 -0.7 -1.5 CDC48 family AAA ATPase compare
MMP_RS06710 -0.7 -1.7 selenium-binding protein compare
MMP_RS07640 -0.7 -2.0 mechanosensitive ion channel family protein compare
MMP_RS06015 -0.7 -1.0 flavodoxin family protein compare
MMP_RS08430 -0.7 -1.9 HAD family hydrolase compare
MMP_RS01030 -0.7 -1.4 MTAP family purine nucleoside phosphorylase compare
MMP_RS02475 -0.7 -1.7 hypothetical protein compare
MMP_RS04900 -0.7 -4.2 hypothetical protein compare
MMP_RS01490 -0.7 -2.5 tetratricopeptide repeat protein compare
MMP_RS06915 -0.7 -1.4 metallophosphoesterase compare
MMP_RS02745 -0.7 -0.7 hypothetical protein compare
MMP_RS05140 -0.7 -1.1 helix-turn-helix transcriptional regulator compare
MMP_RS02740 -0.7 -1.4 hypothetical protein compare
MMP_RS05245 -0.7 -3.2 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS01200 -0.7 -1.7 hypothetical protein compare
MMP_RS07330 -0.7 -3.7 membrane protein compare
MMP_RS00535 -0.7 -0.8 TIGR00375 family protein compare
MMP_RS05875 -0.7 -1.4 hydroxyethylthiazole kinase compare
MMP_RS06215 -0.7 -0.8 30S ribosomal protein S6e compare
MMP_RS03680 -0.7 -2.5 hypothetical protein compare
MMP_RS08585 -0.7 -2.1 flagellin compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Dimetridazole across organisms