Experiment set14S713 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete 2-bromoethanesulfonic acid 0.1 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS07355 -2.9 -1.1 transcription factor S compare
MMP_RS06485 -2.8 -1.0 zinc ribbon domain-containing protein compare
MMP_RS02280 -2.6 -1.0 DUF211 domain-containing protein compare
MMP_RS00130 -2.5 -1.3 nickel-responsive transcriptional regulator NikR compare
MMP_RS03300 -2.5 -0.9 TOBE domain-containing protein compare
MMP_RS03960 -2.4 -0.9 hypothetical protein compare
MMP_RS06355 -2.0 -1.9 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS04710 -2.0 -1.2 hypothetical protein compare
MMP_RS04015 -1.9 -3.1 hypothetical protein compare
MMP_RS06840 -1.9 -1.0 DNA-directed RNA polymerase subunit N compare
MMP_RS01195 -1.8 -1.2 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS08460 -1.8 -1.2 proteasome-activating nucleotidase compare
MMP_RS02900 -1.8 -0.6 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS08310 -1.7 -1.9 TMEM165/GDT1 family protein compare
MMP_RS06885 -1.7 -1.6 50S ribosome-binding GTPase compare
MMP_RS08930 -1.7 -1.7 hypothetical protein compare
MMP_RS03015 -1.7 -4.2 GTP 3' 8-cyclase MoaA compare
MMP_RS08940 -1.6 -1.3 MetS family NSS transporter small subunit compare
MMP_RS01755 -1.5 -0.8 DUF2097 domain-containing protein compare
MMP_RS08210 -1.5 -1.5 phosphatidylglycerophosphatase A compare
MMP_RS02345 -1.5 -1.1 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS02790 -1.5 -1.1 class III signal peptide-containing protein compare
MMP_RS07390 -1.5 -1.0 cell division protein FtsZ compare
MMP_RS02415 -1.5 -1.9 site-specific integrase compare
MMP_RS06340 -1.4 -4.5 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00300 -1.4 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS09020 -1.4 -0.9 hypothetical protein compare
MMP_RS01675 -1.4 -1.4 hypothetical protein compare
MMP_RS06350 -1.4 -2.9 HesA/MoeB/ThiF family protein compare
MMP_RS00945 -1.3 -1.1 PadR family transcriptional regulator compare
MMP_RS03025 -1.3 -1.6 molybdenum cofactor guanylyltransferase compare
MMP_RS03475 -1.3 -0.5 hypothetical protein compare
MMP_RS01005 -1.3 -0.9 riboflavin synthase compare
MMP_RS05920 -1.3 -0.5 50S ribosomal protein L37e compare
MMP_RS03550 -1.3 -1.2 DUF2124 domain-containing protein compare
MMP_RS07635 -1.2 -2.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS00675 -1.2 -0.8 nitroreductase family protein compare
MMP_RS01175 -1.1 -1.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS07885 -1.1 -2.3 tripartite tricarboxylate transporter permease compare
MMP_RS05515 -1.1 -1.6 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS07445 -1.1 -2.8 helix-turn-helix domain-containing protein compare
MMP_RS06700 -1.1 -4.3 hypothetical protein compare
MMP_RS08240 -1.1 -4.0 methanogenesis marker 16 metalloprotein compare
MMP_RS03340 -1.1 -0.8 ABC transporter ATP-binding protein compare
MMP_RS04610 -1.0 -2.2 Dabb family protein compare
MMP_RS01020 -1.0 -0.6 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07815 -1.0 -1.0 DUF2120 domain-containing protein compare
MMP_RS06860 -1.0 -1.1 4Fe-4S binding protein compare
MMP_RS03400 -1.0 -1.2 archease compare
MMP_RS08675 -1.0 -2.1 class III signal peptide-containing protein compare
MMP_RS03080 -0.9 -1.3 universal stress protein compare
MMP_RS03205 -0.9 -0.8 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS06730 -0.9 -0.9 phosphopantothenate/pantothenate synthetase compare
MMP_RS03765 -0.9 -3.0 CopG family ribbon-helix-helix protein compare
MMP_RS02010 -0.9 -3.5 PHP domain-containing protein compare
MMP_RS06345 -0.9 -2.4 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS02135 -0.9 -1.6 DUF5612 domain-containing protein compare
MMP_RS07600 -0.9 -1.0 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS08595 -0.9 -0.8 flagellar protein C compare
MMP_RS02235 -0.9 -4.3 CBS domain-containing protein compare
MMP_RS00295 -0.9 -1.0 gamma carbonic anhydrase family protein compare
MMP_RS07765 -0.9 -4.2 sodium:alanine symporter family protein compare
MMP_RS00305 -0.9 -0.6 phosphoribosyl-ATP diphosphatase compare
MMP_RS03600 -0.8 -0.8 triose-phosphate isomerase compare
MMP_RS05965 -0.8 -2.3 carboxymuconolactone decarboxylase family protein compare
MMP_RS01265 -0.8 -1.5 hypothetical protein compare
MMP_RS01420 -0.8 -1.2 hypothetical protein compare
MMP_RS01385 -0.8 -0.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01100 -0.8 -0.9 ABC transporter ATP-binding protein compare
MMP_RS05540 -0.8 -2.0 hypothetical protein compare
MMP_RS08745 -0.8 -1.5 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS02480 -0.8 -1.2 hypothetical protein compare
MMP_RS07860 -0.8 -0.4 hypothetical protein compare
MMP_RS03580 -0.8 -1.0 signal recognition particle-docking protein FtsY compare
MMP_RS07420 -0.8 -2.2 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS05850 -0.8 -2.0 Ldh family oxidoreductase compare
MMP_RS06680 -0.8 -2.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06770 -0.8 -3.2 DHH family phosphoesterase compare
MMP_RS04890 -0.7 -0.4 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS06005 -0.7 -1.6 heavy-metal-associated domain-containing protein compare
MMP_RS08750 -0.7 -1.5 hypothetical protein compare
MMP_RS08650 -0.7 -1.0 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS05360 -0.7 -1.4 hypothetical protein compare
MMP_RS03110 -0.7 -2.0 glycosyltransferase family 2 protein compare
MMP_RS02840 -0.7 -2.1 DUF123 domain-containing protein compare
MMP_RS06315 -0.7 -0.4 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS00520 -0.7 -0.7 RNA polymerase Rpb4 family protein compare
MMP_RS01415 -0.7 -2.0 DUF2067 domain-containing protein compare
MMP_RS01725 -0.7 -1.6 class I SAM-dependent methyltransferase family protein compare
MMP_RS05925 -0.7 -1.3 small nuclear ribonucleoprotein compare
MMP_RS01180 -0.7 -0.9 XTP/dITP diphosphatase compare
MMP_RS03555 -0.7 -2.8 transcriptional regulator compare
MMP_RS02875 -0.7 -2.3 chorismate pyruvate-lyase family protein compare
MMP_RS04125 -0.7 -2.1 TetR/AcrR family transcriptional regulator compare
MMP_RS06175 -0.7 -2.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS01500 -0.6 -1.0 CBS domain-containing protein compare
MMP_RS06395 -0.6 -1.9 ThiF family adenylyltransferase compare
MMP_RS06460 -0.6 -2.2 pyrimidine dimer DNA glycosylase/endonuclease V compare
MMP_RS01430 -0.6 -2.9 mechanosensitive ion channel family protein compare
MMP_RS07695 -0.6 -1.8 DUF3236 domain-containing protein compare
MMP_RS07630 -0.6 -0.6 ATP-binding cassette domain-containing protein compare
MMP_RS04055 -0.6 -0.8 hypothetical protein compare
MMP_RS00315 -0.6 -2.3 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS02545 -0.6 -2.3 hypothetical protein compare
MMP_RS07575 -0.6 -1.4 RNA ligase partner protein compare
MMP_RS06020 -0.6 -1.1 archaeoflavoprotein AfpA compare
MMP_RS05095 -0.6 -2.9 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS06585 -0.6 -0.8 DMT family protein compare
MMP_RS04850 -0.6 -3.7 UPF0254 family protein compare
MMP_RS02930 -0.6 -1.4 class I SAM-dependent methyltransferase compare
MMP_RS02265 -0.6 -1.4 nitroreductase family protein compare
MMP_RS03445 -0.6 -0.4 methanogenesis marker 17 protein compare
MMP_RS02370 -0.6 -1.2 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS04420 -0.6 -2.1 LysE family translocator compare
MMP_RS00640 -0.6 -2.1 ABC transporter substrate-binding protein compare
MMP_RS03220 -0.6 -1.2 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS04255 -0.6 -2.4 coenzyme F420 hydrogenase subunit beta compare
MMP_RS05830 -0.6 -1.2 peptidyl-prolyl cis-trans isomerase compare
MMP_RS02190 -0.6 -1.1 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS07795 -0.6 -3.1 site-2 protease family protein compare
MMP_RS04100 -0.6 -1.4 hypothetical protein compare
MMP_RS08355 -0.6 -1.5 Na(+)/H(+) antiporter subunit B compare
MMP_RS01325 -0.6 -0.8 dihydroneopterin aldolase family protein compare
MMP_RS08155 -0.5 -1.9 hypothetical protein compare
MMP_RS06590 -0.5 -0.8 GNAT family N-acetyltransferase compare
MMP_RS01335 -0.5 -1.0 prefoldin subunit beta compare
MMP_RS05510 -0.5 -2.4 Rrf2 family transcriptional regulator compare
MMP_RS02700 -0.5 -2.7 formylmethanofuran dehydrogenase subunit C compare
MMP_RS01465 -0.5 -1.5 hypothetical protein compare
MMP_RS01225 -0.5 -1.2 DUF5379 domain-containing protein compare
MMP_RS02245 -0.5 -0.7 hypothetical protein compare
MMP_RS04150 -0.5 -3.1 MFS transporter compare
MMP_RS05085 -0.5 -2.4 AAA family ATPase compare
MMP_RS05245 -0.5 -2.2 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS05695 -0.5 -2.3 phospholipase D-like domain-containing protein compare
MMP_RS02675 -0.5 -1.4 hypothetical protein compare
MMP_RS00725 -0.5 -2.0 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS00710 -0.5 -1.2 hypothetical protein compare
MMP_RS00655 -0.5 -1.0 hypothetical protein compare
MMP_RS06600 -0.5 -0.5 class III signal peptide-containing protein compare
MMP_RS06155 -0.5 -0.9 DUF4186 domain-containing protein compare
MMP_RS07805 -0.5 -2.7 ABC transporter permease compare
MMP_RS07680 -0.5 -1.2 DUF366 family protein compare
MMP_RS01570 -0.5 -0.7 hypothetical protein compare
MMP_RS06855 -0.5 -2.5 hypothetical protein compare
MMP_RS04650 -0.5 -2.6 tetratricopeptide repeat protein compare
MMP_RS01285 -0.5 -2.1 hypothetical protein compare
MMP_RS06630 -0.5 -0.2 UPF0058 family protein compare
MMP_RS03520 -0.5 -0.8 YwbE family protein compare
MMP_RS05450 -0.5 -1.1 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS06665 -0.5 -2.5 glycogen/starch synthase compare
MMP_RS08645 -0.5 -1.6 UPF0179 family protein compare
MMP_RS02000 -0.5 -1.5 radical SAM protein compare
MMP_RS02940 -0.5 -1.9 TatD family hydrolase compare
MMP_RS06400 -0.5 -0.5 4Fe-4S binding protein compare
MMP_RS01150 -0.5 -1.2 aldo/keto reductase compare
MMP_RS06555 -0.5 -0.9 cupin domain-containing protein compare
MMP_RS05580 -0.5 -2.9 glycosyltransferase compare
MMP_RS06900 -0.5 -0.9 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS07970 -0.5 -1.2 hypothetical protein compare
MMP_RS02225 -0.5 -2.0 carbohydrate kinase family protein compare
MMP_RS02015 -0.5 -2.1 amidohydrolase compare
MMP_RS06480 -0.4 -1.3 ABC transporter substrate-binding protein compare
MMP_RS07615 -0.4 -1.4 energy-coupling factor ABC transporter permease compare
MMP_RS00290 -0.4 -1.5 hypothetical protein compare
MMP_RS00770 -0.4 -1.0 hypothetical protein compare
MMP_RS02045 -0.4 -0.6 tRNA-Met compare
MMP_RS06385 -0.4 -2.1 hypothetical protein compare
MMP_RS08820 -0.4 -1.1 hypothetical protein compare
MMP_RS00915 -0.4 -1.4 DUF116 domain-containing protein compare
MMP_RS07645 -0.4 -1.8 aldehyde dehydrogenase family protein compare
MMP_RS06200 -0.4 -2.0 M24 family metallopeptidase compare
MMP_RS03590 -0.4 -1.3 METTL5 family protein compare
MMP_RS06445 -0.4 -1.5 DUF89 domain-containing protein compare
MMP_RS07710 -0.4 -1.6 cell division protein FtsZ compare
MMP_RS07380 -0.4 -0.6 transcription elongation factor Spt5 compare
MMP_RS02870 -0.4 -1.7 hypothetical protein compare
MMP_RS02800 -0.4 -1.4 nucleotidyltransferase domain-containing protein compare
MMP_RS02695 -0.4 -1.7 formylmethanofuran dehydrogenase subunit A compare
MMP_RS01985 -0.4 -1.2 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS07720 -0.4 -2.2 4Fe-4S binding protein compare
MMP_RS04595 -0.4 -1.8 hypothetical protein compare
MMP_RS08605 -0.4 -1.0 flagellar protein E compare
MMP_RS04355 -0.4 -2.9 ribonuclease H family protein compare
MMP_RS03235 -0.4 -1.3 tRNA pseudouridine(13) synthase TruD compare
MMP_RS02970 -0.4 -1.5 hypothetical protein compare
MMP_RS03460 -0.4 -2.0 U32 family peptidase compare
MMP_RS03830 -0.4 -1.4 exodeoxyribonuclease VII large subunit compare
MMP_RS05865 -0.4 -0.7 hypothetical protein compare
MMP_RS09025 -0.4 -0.4 hypothetical protein compare
MMP_RS02680 -0.4 -1.4 ABC transporter permease compare
MMP_RS05635 -0.4 -1.6 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS01030 -0.4 -1.2 MTAP family purine nucleoside phosphorylase compare
MMP_RS01780 -0.4 -1.8 TrmJ/YjtD family RNA methyltransferase compare
MMP_RS01460 -0.4 -1.0 hypothetical protein compare
MMP_RS06035 -0.4 -1.6 glycosyltransferase family 2 protein compare
MMP_RS05500 -0.4 -1.4 2-isopropylmalate synthase compare
MMP_RS05070 -0.4 -1.8 4Fe-4S dicluster domain-containing protein compare
MMP_RS00825 -0.4 -0.7 fumarylacetoacetate hydrolase family protein compare
MMP_RS01240 -0.4 -0.6 7-cyano-7-deazaguanine synthase QueC compare


Specific Phenotypes

For 2 genes in this experiment

For stress 2-bromoethanesulfonic acid in Methanococcus maripaludis S2

For stress 2-bromoethanesulfonic acid across organisms