Experiment set14S712 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Polymyxin B sulfate 0.1 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS01795 -5.9 -1.6 methanogenesis marker 6 protein compare
MMP_RS01020 -5.8 -0.9 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS03960 -5.6 -0.9 hypothetical protein compare
MMP_RS08210 -5.5 -2.3 phosphatidylglycerophosphatase A compare
MMP_RS08635 -5.2 -2.0 UbiA family prenyltransferase compare
MMP_RS02900 -4.8 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS07005 -4.4 -0.7 4Fe-4S binding protein compare
MMP_RS05920 -4.3 -0.7 50S ribosomal protein L37e compare
MMP_RS01500 -4.2 -2.2 CBS domain-containing protein compare
MMP_RS03435 -4.2 -2.2 ketol-acid reductoisomerase compare
MMP_RS06230 -4.2 -3.3 helix-turn-helix domain-containing protein compare
MMP_RS06285 -4.1 -2.2 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS08820 -3.9 -5.7 hypothetical protein compare
MMP_RS04890 -3.9 -0.9 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS06700 -3.8 -11.1 hypothetical protein compare
MMP_RS08715 -3.7 -2.0 formylmethanofuran dehydrogenase subunit B compare
MMP_RS01380 -3.7 -5.6 PHP domain-containing protein compare
MMP_RS03205 -3.7 -1.4 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS07630 -3.7 -1.7 ATP-binding cassette domain-containing protein compare
MMP_RS06110 -3.7 -4.3 ATP-dependent protease LonB compare
MMP_RS01005 -3.6 -1.1 riboflavin synthase compare
MMP_RS04685 -3.5 -3.3 DUF126 domain-containing protein compare
MMP_RS07635 -3.5 -7.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08300 -3.4 -1.3 metal-sulfur cluster assembly factor compare
MMP_RS00915 -3.4 -7.7 DUF116 domain-containing protein compare
MMP_RS06630 -3.4 -0.8 UPF0058 family protein compare
MMP_RS04780 -3.4 -3.0 ribonuclease P compare
MMP_RS06400 -3.4 -1.5 4Fe-4S binding protein compare
MMP_RS03445 -3.3 -1.0 methanogenesis marker 17 protein compare
MMP_RS01175 -3.3 -3.1 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08790 -3.3 -2.5 translation initiation factor IF-2 subunit alpha compare
MMP_RS05515 -3.2 -5.5 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS08460 -3.2 -2.3 proteasome-activating nucleotidase compare
MMP_RS03015 -3.1 -7.6 GTP 3' 8-cyclase MoaA compare
MMP_RS03600 -3.1 -2.4 triose-phosphate isomerase compare
MMP_RS01325 -3.1 -2.0 dihydroneopterin aldolase family protein compare
MMP_RS06355 -3.0 -2.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06680 -2.9 -11.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06350 -2.9 -5.6 HesA/MoeB/ThiF family protein compare
MMP_RS07445 -2.9 -6.7 helix-turn-helix domain-containing protein compare
MMP_RS03640 -2.9 -3.9 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01800 -2.9 -3.6 TIGR00303 family protein compare
MMP_RS06870 -2.8 -5.7 DedA family protein compare
MMP_RS05930 -2.6 -2.2 3-isopropylmalate dehydratase large subunit compare
MMP_RS04585 -2.6 -7.5 AIR synthase related protein compare
MMP_RS07625 -2.6 -3.7 cobalt ECF transporter T component CbiQ compare
MMP_RS05865 -2.5 -3.1 hypothetical protein compare
MMP_RS01225 -2.5 -4.0 DUF5379 domain-containing protein compare
MMP_RS07845 -2.4 -1.7 LL-diaminopimelate aminotransferase compare
MMP_RS00305 -2.4 -1.7 phosphoribosyl-ATP diphosphatase compare
MMP_RS06175 -2.4 -6.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS04775 -2.3 -2.5 adenosylhomocysteinase compare
MMP_RS05835 -2.3 -0.8 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS05430 -2.3 -3.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS08435 -2.3 -2.0 Era-like GTP-binding protein compare
MMP_RS02875 -2.3 -8.3 chorismate pyruvate-lyase family protein compare
MMP_RS06885 -2.2 -2.5 50S ribosome-binding GTPase compare
MMP_RS00685 -2.2 -3.6 2-phospho-L-lactate guanylyltransferase compare
MMP_RS00115 -2.2 -10.1 radical SAM protein compare
MMP_RS06475 -2.2 -3.7 FAD-dependent oxidoreductase compare
MMP_RS05845 -2.2 -1.7 tRNA-intron lyase compare
MMP_RS06295 -2.2 -4.8 methanogenesis marker 14 protein compare
MMP_RS00130 -2.2 -1.2 nickel-responsive transcriptional regulator NikR compare
MMP_RS07525 -2.2 -6.1 4Fe-4S binding protein compare
MMP_RS06120 -2.1 -2.0 UPF0147 family protein compare
MMP_RS03035 -2.1 -3.5 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS00300 -2.1 -0.6 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS08720 -2.1 -1.3 4Fe-4S binding protein compare
MMP_RS06625 -2.0 -1.8 DNA primase compare
MMP_RS02240 -2.0 -2.4 methanogenesis marker 7 protein compare
MMP_RS06840 -2.0 -0.9 DNA-directed RNA polymerase subunit N compare
MMP_RS06685 -2.0 -8.1 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS03305 -2.0 -6.6 winged helix-turn-helix domain-containing protein compare
MMP_RS08645 -2.0 -6.1 UPF0179 family protein compare
MMP_RS02165 -1.9 -6.1 tRNA-dihydrouridine synthase compare
MMP_RS06975 -1.9 -1.7 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS00515 -1.9 -0.8 DUF655 domain-containing protein compare
MMP_RS06895 -1.9 -1.3 selenocysteine-specific translation elongation factor compare
MMP_RS01250 -1.9 -5.8 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS07200 -1.9 -5.8 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05765 -1.8 -4.1 M42 family metallopeptidase compare
MMP_RS06345 -1.8 -6.8 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06270 -1.8 -5.6 TIGR00300 family protein compare
MMP_RS01700 -1.8 -0.9 dihydroxy-acid dehydratase compare
MMP_RS05525 -1.8 -5.8 calcium/sodium antiporter compare
MMP_RS07620 -1.8 -3.5 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS02800 -1.7 -4.8 nucleotidyltransferase domain-containing protein compare
MMP_RS01985 -1.7 -3.1 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS03580 -1.7 -3.1 signal recognition particle-docking protein FtsY compare
MMP_RS07575 -1.7 -3.4 RNA ligase partner protein compare
MMP_RS09020 -1.7 -1.1 hypothetical protein compare
MMP_RS01755 -1.6 -0.9 DUF2097 domain-containing protein compare
MMP_RS02355 -1.6 -1.6 30S ribosomal protein S27ae compare
MMP_RS07380 -1.6 -1.8 transcription elongation factor Spt5 compare
MMP_RS00295 -1.6 -1.7 gamma carbonic anhydrase family protein compare
MMP_RS03400 -1.6 -1.6 archease compare
MMP_RS08745 -1.6 -4.3 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06340 -1.6 -4.5 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00730 -1.6 -3.8 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS03555 -1.6 -7.1 transcriptional regulator compare
MMP_RS06925 -1.6 -1.8 ribonuclease VapC4 compare
MMP_RS05555 -1.5 -1.0 DUF4040 domain-containing protein compare
MMP_RS00725 -1.5 -5.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS01220 -1.5 -4.1 hypothetical protein compare
MMP_RS08600 -1.5 -2.2 flagellar protein D compare
MMP_RS00110 -1.5 -1.9 hypothetical protein compare
MMP_RS05815 -1.5 -1.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS06730 -1.5 -1.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS06855 -1.5 -5.7 hypothetical protein compare
MMP_RS08595 -1.5 -0.9 flagellar protein C compare
MMP_RS05540 -1.5 -1.7 hypothetical protein compare
MMP_RS07735 -1.5 -0.6 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS07615 -1.5 -4.6 energy-coupling factor ABC transporter permease compare
MMP_RS00895 -1.5 -3.2 hypothetical protein compare
MMP_RS03025 -1.5 -3.3 molybdenum cofactor guanylyltransferase compare
MMP_RS05095 -1.4 -5.8 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS08445 -1.4 -3.6 DUF2099 family protein compare
MMP_RS07365 -1.4 -7.1 2-phosphoglycerate kinase compare
MMP_RS04870 -1.4 -3.3 TIGR02253 family HAD-type hydrolase compare
MMP_RS05085 -1.4 -5.6 AAA family ATPase compare
MMP_RS05250 -1.4 -2.2 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08860 -1.4 -2.8 MinD/ParA family protein compare
MMP_RS00695 -1.4 -0.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06020 -1.3 -2.5 archaeoflavoprotein AfpA compare
MMP_RS00290 -1.3 -5.1 hypothetical protein compare
MMP_RS05075 -1.3 -9.1 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS00320 -1.3 -1.4 class I SAM-dependent methyltransferase compare
MMP_RS08650 -1.3 -2.0 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS08940 -1.3 -1.1 MetS family NSS transporter small subunit compare
MMP_RS05245 -1.3 -5.3 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS01980 -1.2 -6.9 trimeric intracellular cation channel family protein compare
MMP_RS06105 -1.2 -4.4 hydrogenase maturation peptidase HycI compare
MMP_RS01365 -1.2 -1.7 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS06200 -1.2 -5.5 M24 family metallopeptidase compare
MMP_RS05100 -1.2 -8.8 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS05070 -1.2 -3.6 4Fe-4S dicluster domain-containing protein compare
MMP_RS05295 -1.2 -4.9 minichromosome maintenance protein MCM compare
MMP_RS05080 -1.2 -6.7 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS03300 -1.2 -0.6 TOBE domain-containing protein compare
MMP_RS06760 -1.2 -2.1 hypothetical protein compare
MMP_RS06865 -1.2 -1.2 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS08590 -1.2 -2.8 flagellin compare
MMP_RS04955 -1.2 -3.8 DNA topoisomerase I compare
MMP_RS05800 -1.2 -5.5 B12-binding domain-containing radical SAM protein compare
MMP_RS05285 -1.1 -3.8 MMPL family transporter compare
MMP_RS01385 -1.1 -0.5 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS05060 -1.1 -6.3 AAA family ATPase compare
MMP_RS07765 -1.1 -5.2 sodium:alanine symporter family protein compare
MMP_RS07755 -1.1 -0.8 DUF555 domain-containing protein compare
MMP_RS05355 -1.1 -0.7 hypothetical protein compare
MMP_RS08200 -1.1 -7.3 archaeosine synthase subunit alpha compare
MMP_RS07535 -1.1 -4.8 4Fe-4S binding protein compare
MMP_RS06290 -1.1 -3.0 DNA repair and recombination protein RadA compare
MMP_RS08370 -1.1 -0.4 cation:proton antiporter subunit C compare
MMP_RS05280 -1.1 -5.5 COG1361 S-layer family protein compare
MMP_RS00040 -1.0 -4.0 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS06315 -1.0 -0.5 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08605 -1.0 -2.9 flagellar protein E compare
MMP_RS05875 -1.0 -2.6 hydroxyethylthiazole kinase compare
MMP_RS07545 -1.0 -0.5 HTH domain-containing protein compare
MMP_RS07695 -1.0 -4.3 DUF3236 domain-containing protein compare
MMP_RS02480 -1.0 -1.3 hypothetical protein compare
MMP_RS05090 -1.0 -5.8 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS06930 -1.0 -6.0 MBL fold metallo-hydrolase compare
MMP_RS04875 -1.0 -2.5 energy-converting hydrogenase B subunit P compare
MMP_RS03550 -1.0 -1.3 DUF2124 domain-containing protein compare
MMP_RS00810 -1.0 -2.4 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07685 -1.0 -4.1 TIGR01212 family radical SAM protein compare
MMP_RS00315 -1.0 -4.0 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS00520 -1.0 -0.9 RNA polymerase Rpb4 family protein compare
MMP_RS05265 -0.9 -1.6 2-isopropylmalate synthase compare
MMP_RS02340 -0.9 -1.3 DNA-directed RNA polymerase subunit E'' compare
MMP_RS08225 -0.9 -5.0 RimK family alpha-L-glutamate ligase compare
MMP_RS02190 -0.9 -1.8 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS06525 -0.9 -0.8 YciI family protein compare
MMP_RS02930 -0.9 -2.2 class I SAM-dependent methyltransferase compare
MMP_RS05055 -0.9 -5.2 DUF166 domain-containing protein compare
MMP_RS01830 -0.9 -0.9 tRNA-Val compare
MMP_RS00325 -0.9 -1.0 RNA-binding protein compare
MMP_RS08750 -0.9 -1.5 hypothetical protein compare
MMP_RS07700 -0.9 -4.7 DUF1188 domain-containing protein compare
MMP_RS00735 -0.9 -2.7 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS08840 -0.9 -4.9 class I SAM-dependent methyltransferase compare
MMP_RS07420 -0.9 -1.8 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS00050 -0.9 -3.2 AarF/UbiB family protein compare
MMP_RS03095 -0.9 -2.8 diphthine synthase compare
MMP_RS00310 -0.9 -5.0 CBS domain-containing protein compare
MMP_RS05545 -0.9 -2.6 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS05925 -0.9 -1.7 small nuclear ribonucleoprotein compare
MMP_RS01545 -0.9 -0.6 CBS domain-containing protein compare
MMP_RS00720 -0.8 -2.7 metal-dependent hydrolase compare
MMP_RS04850 -0.8 -5.3 UPF0254 family protein compare
MMP_RS01330 -0.8 -4.6 DHH family phosphoesterase compare
MMP_RS05345 -0.8 -2.1 hypothetical protein compare
MMP_RS00965 -0.8 -1.3 hypothetical protein compare
MMP_RS01495 -0.8 -3.1 TraB/GumN family protein compare
MMP_RS03470 -0.8 -3.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07385 -0.8 -1.1 protein translocase SEC61 complex subunit gamma compare
MMP_RS07730 -0.8 -0.8 pyruvate synthase subunit beta compare
MMP_RS01725 -0.8 -1.8 class I SAM-dependent methyltransferase family protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress Polymyxin B sulfate in Methanococcus maripaludis S2

For stress Polymyxin B sulfate across organisms